CN104758831A - Traditional Chinese medicine composition for stopping bleeding after delivery - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicine and in particular relates to a traditional Chinese medicine composition for stopping bleeding after delivery and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following Chinese herbal raw materials in parts by weight: 3-8 parts of motherwort herb, 3-8 parts of pseudo-ginseng, 3-8 parts of root of sinkiang arnebia, 3-8 parts of Chinese angelica, 3-8 parts of hairyvein agrimonia herband bud, 3-8 parts of fortune eupatorium herb, 3-8 parts of selfheal, 5-15 parts of zedoary rhizome, 3-8 parts of common scouring rush herb, 3-8 parts of flower of silktree albizzia, 3-5 parts of moutan bark, 3-5 parts of eucommia bark, 5-8 parts of daggertooth pike conger eggs, 5-8 parts of girald pteroxygonum root, 3-5 parts of heterophylly faalsestarwort root and 5-8 parts of longans. The traditional Chinese medicine composition is capable of achieving the effects of promoting the uterus to shrink, arresting sweating and stopping bleeding by use of the actions of the Chinese herbs, and is remarkable in curative effect on profuse uterine bleeding due to extravasated blood stasis and capable of avoiding the anaphylactic reaction caused by medicine residue in the body; and besides, the preparation method of the traditional Chinese medicine composition is simple and easy to implement.

Description

A kind of Chinese medicine composition for hemostasis in puerperal

Technical field

The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine composition for hemostasis in puerperal.

Background technology

After delivery of baby, 24 hours internal hemorrhage amounts are called postpartum hemorrhage more than 500mL person, and 80% occurred in 2 hours puerperal.Late postpartum hemorrhage refers to that childbirth is after 24 hours, bleeds profusely in the uterus occurred within puerperal, is more common in 1 ~ 2 week puerperal.Postpartum hemorrhage is the serious complication of term, is cause one of four of maternal death large reasons.Be first reason causing maternal death in recent years at China's postpartum hemorrhage, particularly in Far-away Backward Areas, this situation is more outstanding always.The sickness rate of postpartum hemorrhage accounts for 2% ~ 3% of childbirth sum, and because the subjective factors measuring and collect amount of bleeding is comparatively large, actual sickness rate is higher.

The pathogenic factor of postpartum hemorrhage is followed successively by uterine contractions fatigue, soft birth canal laceration, placenta factors and coagulation disorders.Four large reasons can merge existence, also can reciprocal causation.Clinical treatment is generally hemostasis and treatment of blood transfusion, but most uterine contraction agent has side effect, and is not suitable for allergic constitution puerpera, narrow application range.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine composition for hemostasis in puerperal and preparation method thereof, by the effect of Chinese medicine, reach the effect promoting the hemostasis of uterine contraction, arresting sweating, caused metrorrhagia is not gone out for congestion evident in efficacy, medicine can be avoided to remain in vivo cause allergic reaction, and there is simple and easy to do preparation method.

The invention provides a kind of Chinese medicine composition for hemostasis in puerperal, formulated by the raw material of Chinese medicine of following parts by weight: Herba Leonuri 3 ~ 8 parts, Radix Notoginseng 3 ~ 8 parts, Radix Arnebiae (Radix Lithospermi) 3 ~ 8 parts, Radix Angelicae Sinensis 3 ~ 8 parts, Herba Agrimoniae 3 ~ 8 parts, Herba Eupatorii 3 ~ 8 parts, Spica Prunellae 3 ~ 8 parts, Rhizoma Curcumae 5 ~ 15 parts, Herba Equiseti Hiemalis 3 ~ 8 parts, Flos Albiziae 3 ~ 8 parts, Cortex Moutan 3 ~ 5 parts, the Cortex Eucommiae 3 ~ 5 parts, 5 ~ 8 parts, Muraenesocis cinereus ovum, Radix Pteroxygoni Giraldii 5 ~ 8 parts, Radix Pseudostellariae 3 ~ 5 parts and Arillus Longan 5 ~ 8 parts.

More preferably formulated by the raw material of Chinese medicine of following parts by weight: Herba Leonuri 6 parts, Radix Notoginseng 5 parts, Radix Arnebiae (Radix Lithospermi) 6 parts, Radix Angelicae Sinensis 6 parts, Herba Agrimoniae 6 parts, Herba Eupatorii 6 parts, Spica Prunellae 6 parts, Rhizoma Curcumae 10 parts, Herba Equiseti Hiemalis 7 parts, Flos Albiziae 6 parts, Cortex Moutan 4 parts, the Cortex Eucommiae 4 parts, 8 parts, Muraenesocis cinereus ovum, Radix Pteroxygoni Giraldii 8 parts, Radix Pseudostellariae 5 parts and Arillus Longan 5 parts.

Preparation method takes raw material of Chinese medicine according to formula and joins in container, adds water to cover powder and soak 25-30 minute, then add water and no powder 5-7 centimetre, decocts with high heat and uses slow fire boiling 30-40 minute again instead to seething with excitement, get filtrate; And then add water and do not have powder 5-7 centimetre, decoct with high heat and uses slow fire boiling 30-40 minute again instead to boiling, then remove slag and get filtrate, twice filtrate merges.

Pharmacology analysis:

Herba Leonuri: bitter, pungent, is slightly cold.Return liver, pericardium channel.Promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.

Muraenesocis cinereus ovum: strengthening by means of tonics.Main body void is frail; Liver cirrhosis; Fatty liver; Neurasthenia; Anemia.

Radix Notoginseng: hemostasis dissipating blood stasis, subduing swelling and relieving pain, has dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.Cure mainly spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast ventral spine pain, tumbling down swells and ache.

Cortex Moutan: bitter, pungent, is slightly cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.

Radix Arnebiae (Radix Lithospermi): sweet, salty, cold.GUIXIN, Liver Channel.Removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.

Radix Angelicae Sinensis: pungent, sweet, warm.Promoting blood circulation and breaking stagnation, menstruction regulating and pain relieving.Control menoxenia.

Herba Agrimoniae: bitter, puckery is flat.GUIXIN, Liver Channel.Astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.For hemoptysis, spit blood, metrostaxis, malaria, dysentery, de-power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia.

Herba Eupatorii: pungent, flat.Return spleen, stomach, lung meridian.Removing dampness by means of aromatics, appetizing of being amusing, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, heat-damp in summer table disease, feeling of fullness in the head is uncomfortable in chest.

Spica Prunellae: pungent, bitter, cold.Return liver, gallbladder meridian.Relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.

Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.Circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.

Herba Equiseti Hiemalis: sweetness and bitterness, flat.Enter lung, liver, gallbladder meridian.Promoting tissue regeneration by removing blood stasis, relaxing muscles and tendons and activating QI and blood in the collateral.Infusing drugs in wine takes, the strong muscles and bones of energy, dispelling the wind and dampness pathogens osteodynia.Leaf controls traumatic injury, synthetism.

Flos Albiziae: sweet, flat.GUIXIN, liver, lung meridian.Resolving stagnation for tranquilization, promoting blood circulation and detumescence.For irritability, melancholy insomnia, lung abscess skin ulcer swells, and falls and flutters the pain of injury.

The Cortex Eucommiae: sweet, temperature.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, antiabortive.For lumbago due to renal deficiency, muscles and bones is unable, blood leaking in gestation, frequent fetal movement; Hypertension.

Radix Pteroxygoni Giraldii: bitter, cold.Removing heat from blood repercussive, damp eliminating is detoxified.Control haematemesis, epistaxis, have blood in stool, dysentery, bleeding not during menses, rheumatic arthralgia, furuncle, burn.

Radix Pseudostellariae: sweet, micro-hardship is flat.Return spleen, lung meridian.Replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.

Arillus Longan: sweet, flat warm, nontoxic.Enter the heart, spleen, stomach.Reinforcing the heart spleen, replenishing QI and blood, strengthening the spleen and stomach, supports muscle.Worry impairing spleen, dizzy, insomnia, severe palpitation, emptyly wins, and after being ill or puerperal asthenia, and to lose blood disease due to insufficiency of the spleen caused hematochezia.

The present invention is Chinese medicine preparation sheerly, by the effect of Chinese medicine, reach the effect promoting the hemostasis of uterine contraction, arresting sweating, caused metrorrhagia is not gone out for congestion evident in efficacy, medicine can be avoided to remain in vivo cause allergic reaction, and there is simple and easy to do preparation method.

Outcome measure:

Effective: in the 15min that takes medicine, the bleeding of activeness disappears, sign recovers normal.

Effective: in the 30min that takes medicine, the bleeding of activeness is alleviated, sign starts to recover normal.

Invalid: all diseases are without improvement.

Therapeutic outcome: treatment patient 60 example, takes medicine of the present invention when there is bleeding, a potion, potion 200g.Effective 50 examples, account for 83%; Take a turn for the better 4 examples, accounts for 6.7%; Invalid 6 examples, account for 10%.

Attached several routine case is described further:

Case 1: Jiao, female, 32 years old, two tires are income institute when December 23 days 9 just before giving birth.Produce inspection: palace is high by 38, abdominal circumference 107, fetal rhythm is normal, and blood pressure is normal, and palace mouth opens 3 centimetres, first appears, S=-2, and fetal membrane does not break, and uterine contraction 30 seconds/1-2 divides, by force.Edema of pair of lower extremities prolongs and abdominal part, and B ultrasonic prompting fetal survival, single tire, polyhydramnios, fetal gut is slightly expanded, biparietal diameter 9.57CM, head circumference 34 centimetres.Routine urinalysis prompting protein negative.Wait to produce in delivery room after routine blood test prompting hemoglobin 95G/L. is admitted to hospital, open 7 centimetres, S=0 in December palace mouth on 24 zero point, fetal membrane breaks, and color is clear, forewaters about 300 milliliters.0. 50 points of palace mouths are opened entirely, and hold one's breath half an hour Descending of fetal head of S=+1. is slow, and S=+2, uterine contraction is strong, and 30 seconds/1-2 divides.Consider that two journeys are stagnated and prepare row cesarean section.Sew up myometrium after delivery of baby, check and find that uterine incision has oozing of blood, director's sewing hemostasis, massage uterus, uterine contraction agent there all is not effect, and the soft picture in uterus is bag-shaped.Hemorrhage general 500 milliliters, then take Chinese medicine preparation of the present invention, hemorrhage minimizing after 10 minutes, after half an hour, amount of bleeding recovers normal at once.

Case 2: the Qin so-and-so, female, 29 years old, with menolipsis 40+2 week, require that operation is admitted to hospital.Contracting agent, weak effect.The uterus cluster that carries out (than Yang Shi) is sewed up, and rear metrorrhagia reduces.Post operative diagnosis: 1. pregnant 1 produce 40+3 week pregnant LOA Cesarean esction 2. malformed uterus (saddle) 3. postpartum hemorrhage.Then give Chinese medicine preparation of the present invention to take, bleeding is prevented, and sign recovers normal.

Detailed description of the invention

Embodiment 1:

For a Chinese medicine composition for hemostasis in puerperal, formulated by the raw material of Chinese medicine of following parts by weight: Herba Leonuri 6 parts, Radix Notoginseng 5 parts, Radix Arnebiae (Radix Lithospermi) 6 parts, Radix Angelicae Sinensis 6 parts, Herba Agrimoniae 6 parts, Herba Eupatorii 6 parts, Spica Prunellae 6 parts, Rhizoma Curcumae 10 parts, Herba Equiseti Hiemalis 7 parts, Flos Albiziae 6 parts, Cortex Moutan 4 parts, the Cortex Eucommiae 4 parts, 8 parts, Muraenesocis cinereus ovum, Radix Pteroxygoni Giraldii 8 parts, Radix Pseudostellariae 5 parts and Arillus Longan 5 parts.

Preparation method takes raw material of Chinese medicine according to formula and joins in container, adds water to cover powder and soak 28 minutes, then add water and do not have powder 6 centimetres, decocts with high heat and uses slow fire boiling again instead 35 minutes to boiling, get filtrate; And then add water and do not have powder 6 centimetres, decoct with high heat and uses slow fire boiling again instead 35 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.

Claims (2)

1., for a Chinese medicine composition for hemostasis in puerperal, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Leonuri 3 ~ 8 parts, Radix Notoginseng 3 ~ 8 parts, Radix Arnebiae (Radix Lithospermi) 3 ~ 8 parts, Radix Angelicae Sinensis 3 ~ 8 parts, Herba Agrimoniae 3 ~ 8 parts, Herba Eupatorii 3 ~ 8 parts, Spica Prunellae 3 ~ 8 parts, Rhizoma Curcumae 5 ~ 15 parts, Herba Equiseti Hiemalis 3 ~ 8 parts, Flos Albiziae 3 ~ 8 parts, Cortex Moutan 3 ~ 5 parts, the Cortex Eucommiae 3 ~ 5 parts, 5 ~ 8 parts, Muraenesocis cinereus ovum, Radix Pteroxygoni Giraldii 5 ~ 8 parts, Radix Pseudostellariae 3 ~ 5 parts and Arillus Longan 5 ~ 8 parts.

2. as claimed in claim 1 a kind of for puerperal hemostasis Chinese medicine composition, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Leonuri 6 parts, Radix Notoginseng 5 parts, Radix Arnebiae (Radix Lithospermi) 6 parts, Radix Angelicae Sinensis 6 parts, Herba Agrimoniae 6 parts, Herba Eupatorii 6 parts, Spica Prunellae 6 parts, Rhizoma Curcumae 10 parts, Herba Equiseti Hiemalis 7 parts, Flos Albiziae 6 parts, Cortex Moutan 4 parts, the Cortex Eucommiae 4 parts, 8 parts, Muraenesocis cinereus ovum, Radix Pteroxygoni Giraldii 8 parts, Radix Pseudostellariae 5 parts and Arillus Longan 5 parts.