CN104758423A - Traditional Chinese medicine prescription for treating gallstone - Google Patents
Traditional Chinese medicine prescription for treating gallstone Download PDFInfo
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- CN104758423A CN104758423A CN201510192959.4A CN201510192959A CN104758423A CN 104758423 A CN104758423 A CN 104758423A CN 201510192959 A CN201510192959 A CN 201510192959A CN 104758423 A CN104758423 A CN 104758423A
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Abstract
The invention discloses a traditional Chinese medicine prescription for treating gallstone. The traditional Chinese medicine prescription is prepared from the following main raw materials in parts by mass: 10-13 parts of white peony root, 11-13 parts of herb of lilac pink, 10-13 parts of small centipeda herb, 7-12 parts of brooklet anemine root, 12-18 parts of cape jasmine fruit, 9-12 parts of herb of Chinese goldsaxifrage, 5-7 parts of pyrrosia leaf, 8-13 parts of szechwan chinaberry fruit, 10-13 parts of herb of spicate clerodendranthus, 9-16 parts of Indian buead, 10-15 parts of bitter orange, 3-5 parts of mirabilite and 9-13 parts of herb of Japanese hop. The traditional Chinese medicine prescription has the effects of discharging liver and regulating qi, clearing heat and promoting dieresis, as well as removing blood stasis and dispersing phlegm, can effectively promote bilification, and is beneficial for discharging stones.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly a kind of Chinese medicinal formulae for the treatment of cholelithiasis.
Background technology
Cholelithiasis refers to the disease caused by calculus occurred in gallbladder, is a kind of commonly encountered diseases.Can cause the disease of the symptoms such as violent stomachache, jaundice, fever, being also called cholelithiasis, is modal biliary tract.Be mainly seen in adult, women is more than male, and within 40 years old, sequela rate increases with the age and increases.Calculus is cholesterol calculus or the mixed calculus based on cholesterol and black bile pigment calculus.Along with growth in the living standard, the change of dietary habit, the improvement of sanitary condition, the cholelithiasis of China changes into based on gallbladder cholesterol calculus for main gradually by with the bile pigment calculus of bile duct.
Chinese medicine thinks that the formation of cholelithiasis is relevant to gallbladder liver, and gallbladder depends on liver, and the operation of gallbladder and irritability and taste assimilate food elite, has excretion absurd creature function.Due to eating and drinking without temperance, or eating and drinking too much at one meal, impairing the spleen and stomach, dysfunction of the spleen in transportation, water-damp not being transformed, amass and wet into expectorant, raw in expectorant is mixed, hinder mechanism of qi, the catharsis of depression and stagnation of QI bile is not normal, strongly fragrant heat-transformation fire-transformation of a specified duration, phlegm-damp heat-dissipating, damp and hotly ties mutually with expectorant, and combination of phlegm and heat damp-heat accumulation stone becomes cholelithiasis for a long time.In addition, surfeit delicious food savoury, or insobriety at ordinary times, or surfeit is pungent, make in damp-heat in middle-JIAO raw, soil is counter insults wood, and damp and hot fumigation is in liver and gall, and liver and gall are lost in catharsis, and cholestasis is accumulate steaming also can form cholelithiasis by damp and hot.
Cholelithiasis happens occasionally in daily life, and especially along with the increasing of people's operating pressure, undesirable element custom etc. all can increase the probability of suffering from cholelithiasis.The cause of disease of cholelithiasis is very complicated, anyly affects cholesterol and bile acid concentration ratio changes and cause the factor of cholestasis to cause calculus.As certain areas and race resident, estrogen, obesity, gestation, high fat diet, long-term parenteral, diabetes, hyperlipemia, pacing stomach or gastrointestinal anastomosis Post operation, terminal ileum disease and ileal resection is postoperative, liver cirrhosis, hemolytic anemia etc.In China, the cholelithiasis sickness rate of southwest is relatively high, may be relevant with dietary habit.
At present, the medicine for the treatment of cholelithiasis is a lot, publication number CN 103272189 A(application number 201310242331.1) patent document discloses a kind of medicine for the treatment of cholelithiasis, be made up of the crude drug of following weight: Spora Lygodii 20g, Fructus Gardeniae 20g, Herba Lysimachiae 15g, Radix Bupleuri 15g, Herba Dendrobii 10g, Spica Prunellae 10g, Herba Hedyotidis Diffusae 10g, Herba Taraxaci 10g, Radix Et Rhizoma Rhei 10g, Semen Plantaginis 10g, Rhizoma Curcumae Longae 10g, Radix Clematidis 10g, Herba Scutellariae Barbatae 10g, Herba Silybi mariani 10g, Radix Salviae Miltiorrhizae 10g, Rhizoma Dioscoreae 10g, Pericarpium Citri Reticulatae Viride 10g, Radix Angelicae Sinensis 10g, Fructus Corni 10g, Radix Pseudostellariae 10g, Rhizoma Polygoni Cuspidati 10g, Bulbus Fritillariae Thunbergii 10g, Radix Paeoniae Alba 10g, Radix Codonopsis 8g, Stigma Maydis 8g, Squama Manis 8g, Pericarpium Citri 8g, Semen Coicis 8g, Semen Persicae 8g, Rhizoma Alismatis 8g, Caulis Spatholobi 5g and Radix Glycyrrhizae 10g.Publication number CN 104288296 A(application number 201410625113.0) patent document discloses a kind of Chinese medicine composition for the treatment of cholelithiasis, be prepared from by 8 taste medical materials such as Herba Glechomae, Talcum, the Radix Astragali, Herba Artemisiae Scopariae, Pericarpium Citri Reticulatae Viride, Semen Plantaginis, the Radix Aucklandiae and Radix Glycyrrhizaes.Publication number CN 103933478 A(application number 201410162225.7) patent document discloses a kind of medicine for the treatment of cholelithiasis, it is made up of the raw material of following parts by weight: Oletum Trogopterori 5-10 part, Rhizoma Cyperi 10-20 part, Radix Curcumae 20-30 part, Herba Artemisiae Scopariae 15-25 part, Herba Portulacae 30-40 part, Herba Centipedae 1-5 part, RADIX CURCUMAE from Sichuan of China 1-5 part, Rhizoma Pinelliae Preparata 5-10 part, Radix Aucklandiae 5-15 part.
Current gallstone treatment method mainly operative treatment, external knock wave shock wave lithotripsy etc.Operation risk is high, and expense is large, and relapse rate is high, and may leave sequela; External knock wave shock wave lithotripsy the patient to some functional defecies and biliary tract stenosis or blocking should not be suitable for, and shock wave has certain injury to human organ; And for the medicine of calculus lithodialysis on market today, unsatisfactory curative effect, side effect is large.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind of Chinese medicinal formulae for the treatment of cholelithiasis, has depressed liver-energy dispersing and QI regulating, clearing away heat-damp and promoting diuresis, and effect of blood stasis-eliminating and stagnation-dissipating has obvious curative effect to cholelithiasis.Another object of the present invention is just to provide the preparation method of the Chinese medicinal formulae of above-mentioned treatment cholelithiasis.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicinal formulae for cholelithiasis, take off the primary raw material stating weight proportion and be prepared from: Radix Paeoniae Alba 10-13 part; Herba Dianthi 11-13 part; Herba Centipedae 10-13 part; Radix Anemones Rivularis 7-12 part; Fructus Gardeniae 12-18 part; Golden saxifrage 9-12 part; Folium Pyrrosiae 5-7 part; Fructus Toosendan 8-13 part; Herba clerodendranthi spicati 10-13 part; Poria 9-16 part; Fructus Aurantii 10-15 part; Natrii Sulfas 3-5 part; Herba humuli scandentis 9-13 part.
Treat a Chinese medicinal formulae for cholelithiasis, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Radix Paeoniae Alba 11-12 part; Herba Dianthi 11.5-12.5 part; Herba Centipedae 11-12 part; Radix Anemones Rivularis 8-11 part; Fructus Gardeniae 14-16 part; Golden saxifrage 10-11 part; Folium Pyrrosiae 5.5-6.5 part; Fructus Toosendan 9-12 part; Herba clerodendranthi spicati 11-12 part; Poria 11-14 part; Fructus Aurantii 11-14 part; Natrii Sulfas 3.5-4.5 part; Herba humuli scandentis 10-12 part.
Treat a Chinese medicinal formulae for cholelithiasis, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from
:the Radix Paeoniae Alba 11.5 parts; Herba Dianthi 12 parts; Herba Centipedae 11.5 parts; Radix Anemones Rivularis 9 parts; Fructus Gardeniae 15 parts; Golden saxifrage 10.5 parts; Folium Pyrrosiae 6 parts; Fructus Toosendan 11 parts; Herba clerodendranthi spicati 11.5 parts; 12 parts, Poria; Fructus Aurantii 13 parts; 4 parts, Natrii Sulfas; Herba humuli scandentis 11 parts.
Present invention also offers the preparation method Chinese medicinal formulae of above-mentioned treatment cholelithiasis being made pharmaceutically acceptable powder, decoction, pill, tablet and granule.
The preparation method of the Chinese medicinal formulae powder of described treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loading steams in container, airtight, and water proof heating 6-10 hour, takes out, dry, pulverize, excessively 100-140 mesh sieve (preferred 110-130 mesh sieve excessively, was more preferably 120 mesh sieves);
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dry in the air cool, pulverize, excessively 100-140 mesh sieve (preferred 110-130 mesh sieve excessively, was more preferably 120 mesh sieves);
(3) by Natrii Sulfas porphyrize, 100-140 mesh sieve (preferred 110-130 mesh sieve excessively, was more preferably 120 mesh sieves) excessively;
(4) Radix Paeoniae Alba, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis are placed in pot, moderate heat fried dry, pulverize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(5) by step (1)-(4) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
The preparation method of the Chinese medicinal formulae powder of above-mentioned treatment cholelithiasis, the consumption of the preferred yellow wine of step (1) is the 20%-40% of Radix Anemones Rivularis quality, and the consumption being more preferably yellow wine is 30% of Radix Anemones Rivularis quality.
Instructions of taking: at every turn get 8-10g, is placed in tea bag, soaks, every day 2-3 time, 2 days courses for the treatment of by the warm waters of about 50 DEG C.
The preparation method of the Chinese medicinal formulae decoction of described treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 40-50 minute, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filters, merging filtrate, be concentrated into 1/2 of original volume, obtain decoction.
Instructions of taking: each 60-90ml, with the warm water delivery service of about 35 DEG C, every day 2-3 time, 2 days courses for the treatment of.
The preparation method of the Chinese medicinal formulae pill of described treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 40-50 minute, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filter, merging filtrate, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste, make pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm).
Instructions of taking: each 10-15 ball, every day 3 times, 2 days courses for the treatment of.
The preparation method of the Chinese medicinal formulae tablet of described treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 40-50 minute, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filters, merging filtrate, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste, make tablet.
Instructions of taking: each 2-3 sheet, every day 3 times, 2 days courses for the treatment of.
The preparation method of the Chinese medicinal formulae granule of described treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soaks 30 minutes, moderate heat decocts 40-50 minute, add step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filters, merging filtrate, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste, add simple syrup, mixing, makes uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
The preparation method of the Chinese medicinal formulae granule of above-mentioned treatment cholelithiasis, the consumption of the preferred simple syrup of step (4) is the 5%-7% of thick paste quality, and the consumption being more preferably simple syrup is 6% of thick paste quality.
Instructions of taking: each 1 bag, every day 3 times, 2 days courses for the treatment of.
Technical advantage of the present invention is mainly reflected in:
1, Chinese medicinal formulae of the present invention absorbs fast, good effect, short treating period, and comprehensive killing pathogenic bacteria effectively stops cholelithiasis regrowth.Simultaneously can lithodialysis rapidly, final calculus is smashed and is excreted, and function of gallbladder promoting diuresis, thoroughly cures cholelithiasis.
2, a large amount of clinical observation result shows that Chinese medicinal formulae of the present invention has depressed liver-energy dispersing and QI regulating, clearing away heat-damp and promoting diuresis, and effect of blood stasis-eliminating and stagnation-dissipating, effectively promotes bile secretion, is conducive to the discharge of calculus.
3, selected materials great majority of the present invention are Chinese medicine material, and medical material is easy to get, and cost is low.
4, the present invention adopts the preparation of pure natural medical material, and all meticulous compatibility forms, and drug effect is lastingly powerful, determined curative effect, does not injure the intestines and stomach, has no side effect, and can not produce drug dependence.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a Chinese medicinal formulae for cholelithiasis, take off the primary raw material stating weight proportion and be prepared from (getting 70g for every part): the Radix Paeoniae Alba 10 parts; Herba Dianthi 11 parts; Herba Centipedae 10 parts; Radix Anemones Rivularis 7 parts; Fructus Gardeniae 12 parts; Golden saxifrage 9 parts; Folium Pyrrosiae 5 parts; Fructus Toosendan 8 parts; Herba clerodendranthi spicati 10 parts; 9 parts, Poria; Fructus Aurantii 10 parts; 3 parts, Natrii Sulfas; Herba humuli scandentis 9 parts.
The preparation method of the Chinese medicinal formulae powder of above-mentioned treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, and load and steam in container, airtight, water proof heats 8 hours, takes out, dry, pulverize, and crosses 120 mesh sieves;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 35 minutes, takes out, and sieve removes Testa Tritici, dries in the air cool, pulverizes, and crosses 120 mesh sieves;
(3) by Natrii Sulfas porphyrize, 120 mesh sieves are crossed;
(4) Radix Paeoniae Alba, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis are placed in pot, moderate heat fried dry, pulverize, cross 140 mesh sieves;
(5) by step (1)-(4) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
Instructions of taking: at every turn get 10g, is placed in tea bag, soaks, every day 3 times, 2 days courses for the treatment of by the warm waters of about 50 DEG C.
embodiment 2treat a Chinese medicinal formulae for cholelithiasis, take off the primary raw material stating weight proportion and be prepared from (every part of 20g): the Radix Paeoniae Alba 13 parts; Herba Dianthi 13 parts; Herba Centipedae 13 parts; Radix Anemones Rivularis 12 parts; Fructus Gardeniae 18 parts; Golden saxifrage 12 parts; Folium Pyrrosiae 7 parts; Fructus Toosendan 13 parts; Herba clerodendranthi spicati 13 parts; 16 parts, Poria; Fructus Aurantii 15 parts; 5 parts, Natrii Sulfas; Herba humuli scandentis 13 parts.
The preparation method of the Chinese medicinal formulae decoction of above-mentioned treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, and load and steam in container, airtight, water proof heats 8 hours, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 35 minutes, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 45 minutes, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 35 minutes, filter, merging filtrate, be concentrated into 1/2 of original volume, obtain decoction.
Instructions of taking: each 80ml, every day 3 times, 2 days courses for the treatment of.
model case onexue XX, man, 49 years old, people from Ganzhou City of Jiangxi Province.Suffer from more than 10 years of cholelithiasis, do not carry out operative treatment always, often have epigastric discomfort, just can alleviate preferably after taking calculus medicine and antibiotic medicine.Go hospital doctor all to advise he excises gallbladder at every turn, but he because fearing operation in tow always.Pain increases the weight of in recent years, duration extension, and B ultrasonic shows: the about 4*3cm calculus of gallbladder, gallbladder wall thickness, stones in intrahepatic bile duct is broadening.
After taking 2 courses for the treatment of of Chinese medicinal formulae decoction (embodiment 2) of gained of the present invention treatment cholelithiasis, symptom obviously alleviates, pain transference cure.After continuing to take 2 courses for the treatment of, check B ultrasonic: calculus disappears completely, and gallbladder no abnormality seen, reaches clinical cure.Later stage follows up a case by regular visits to and learns and fully recover, and gallbladder does not occur calculus more so far.
embodiment 3treat a Chinese medicinal formulae for cholelithiasis, take off the primary raw material stating weight proportion and be prepared from (getting 50g for every part): the Radix Paeoniae Alba 11 parts; Herba Dianthi 11.5 parts; Herba Centipedae 11 parts; Radix Anemones Rivularis 8 parts; Fructus Gardeniae 14 parts; Golden saxifrage 10 parts; Folium Pyrrosiae 5.5 parts; Fructus Toosendan 9 parts; Herba clerodendranthi spicati 11 parts; 11 parts, Poria; Fructus Aurantii 11 parts; 3.5 parts, Natrii Sulfas; Herba humuli scandentis 10 parts.
The preparation method of the Chinese medicinal formulae pill of above-mentioned treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, and load and steam in container, airtight, water proof heats 8 hours, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 35 minutes, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 45 minutes, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 35 minutes, filter, merging filtrate, being concentrated into relative density is 1.15(25 DEG C) thick paste, make the pill that diameter is 4mm.
Instructions of taking: each 10 balls, every day 3 times, 2 days courses for the treatment of.
embodiment 4treat a Chinese medicinal formulae for cholelithiasis, take off the primary raw material stating weight proportion and be prepared from (getting 25g for every part): the Radix Paeoniae Alba 12 parts; Herba Dianthi 12.5 parts; Herba Centipedae 12 parts; Radix Anemones Rivularis 11 parts; Fructus Gardeniae 16 parts; Golden saxifrage 11 parts; Folium Pyrrosiae 6.5 parts; Fructus Toosendan 12 parts; Herba clerodendranthi spicati 12 parts; 14 parts, Poria; Fructus Aurantii 14 parts; 4.5 parts, Natrii Sulfas; Herba humuli scandentis 12 parts.
The preparation method of the Chinese medicinal formulae tablet of above-mentioned treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, and load and steam in container, airtight, water proof heats 8 hours, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 35 minutes, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 45 minutes, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 35 minutes, filter, merging filtrate, being concentrated into relative density is 1.15(25 DEG C) thick paste, make tablet.
Instructions of taking: each 2-3 sheet, every day 3 times, 2 days courses for the treatment of.
model case twoxu XX, female, 38 years old, people from Zibo City of Shandong Province.Start before half wheat harvesting period to occur right Upper abdominal pain, paroxysmal colic, about ensiform process of sternum, pain once in a while, gradually starts to take on to the right, back, left hand diffuses.Often there is right Upper abdominal pain in ensuing time back warp, is paroxysmal colic, companion's nausea and vomiting.Remove examination in hospital, through B ultrasonic display cholelithiasis 28mm, gallbladder wall is crude, is diagnosed as cholelithiasis.Expectant treatment is after one week, and nothing is obviously alleviated.
After taking 2 courses for the treatment of of Chinese medicinal formulae tablet (embodiment 4) of gained of the present invention treatment cholelithiasis, stomachache obviously alleviates, and B ultrasonic display cholelithiasis obviously diminishes.After continuing to take 2 courses for the treatment of, all malaise symptoms disappear, and B ultrasonic shows cholelithiasis and disappears completely, reaches clinical cure.Tracing observation 1 year, without recurrence.
embodiment 5treat a Chinese medicinal formulae for cholelithiasis, take off the primary raw material stating weight proportion and be prepared from (getting 30g for every part): the Radix Paeoniae Alba 11.5 parts; Herba Dianthi 12 parts; Herba Centipedae 11.5 parts; Radix Anemones Rivularis 9 parts; Fructus Gardeniae 15 parts; Golden saxifrage 10.5 parts; Folium Pyrrosiae 6 parts; Fructus Toosendan 11 parts; Herba clerodendranthi spicati 11.5 parts; 12 parts, Poria; Fructus Aurantii 13 parts; 4 parts, Natrii Sulfas; Herba humuli scandentis 11 parts.
The preparation method of the Chinese medicinal formulae granule of above-mentioned treatment cholelithiasis, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, and load and steam in container, airtight, water proof heats 8 hours, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 35 minutes, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soaks 30 minutes, moderate heat decocts 45 minutes, add step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 35 minutes, filter, merging filtrate, being concentrated into relative density is 1.15(25 DEG C) thick paste, add simple syrup, mixing, makes uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
Instructions of taking: each 1 bag, every day 3 times, 2 days courses for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Radix Paeoniae Alba: bitter in the mouth, acid, cold in nature.Return liver, spleen channel.For the dry root of ranunculaceae plant Radix Paeoniae.There is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, effect of astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Herba Dianthi: bitter in the mouth, cold in nature.GUIXIN, small intestine meridian.For the dry aerial parts of pinkwort Herba Dianthi or Dianthus chinensis.There is inducing diuresis for treating stranguria syndrome, effect that removing blood stasis stimulates the menstrual flow.For pyretic stranguria, stranguria with blood.Stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, menstruation apolipsis.
Herba Centipedae: acrid in the mouth, warm in nature.Return lung, Liver Channel.For the dry herb of feverfew Herba Centipedae.There is clearing the nasal passage, effect of cough-relieving.For headche due to wind-cold, cough with copious phlegm, has a stuffy nose obstructed, nasal sinusitis watery nasal discharge.
Radix Anemones Rivularis: bitter in the mouth, pungent, warm in nature.Return lung, stomach, Liver Channel.For the root of the grass that ranunculaceae plant Radix Anemones Rivularis and little Hua tiger slap.Containing betulic acid, Herba Veronicastri Sibirici Saponin, Radix Anemones Rivularis Saponin A, B, C, D and Saponin AR-1, AR-3.There is heat-clearing and toxic substances removing, relaxing muscles and tendons to promote blood circulation, effect of reducing swelling and alleviating pain.For laryngopharynx swelling and pain, mumps, scrofula tuberculosis, swollen ulcer drug, malaria, cough, jaundice due to damp-heat, rheumatalgia, stomachache, toothache, traumatic injury.
Fructus Gardeniae: bitter in the mouth, cold in nature.GUIXIN, lung, tri-jiao channel.Another name SHANZHIZI etc.For the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae.There is pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, effect of removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, yellow cellulitis dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Golden saxifrage: bitter in the mouth, cold in nature.For the herb of the golden waist of Saxifragaceae golden saxifrage platymiscium China.There is heat clearing away, diuresis, jaundice eliminating, calculus removing effect.For icterohepatitis, cystitis, Biliary Calculi.
Folium Pyrrosiae: sweet in the mouth, hardship, cold nature.Return lung, urinary bladder channel.For the dried leaves of Plants of Polypodiaceae pyrrosia sheareriChing, Folium Pyrrosiae or pyrrosia petiolosaChing.There is inducing diuresis for treating stranguria syndrome, effect of clearing away heat to stop bleeding.For pyretic stranguria, stranguria with blood, stone forest, urinary obstruction, drenches the puckery pain of drop, spits blood, epistaxis, hematuria, metrorrhagia, and lung-heat danger is coughed.
Fructus Toosendan: bitter in the mouth, cold in nature.Return liver, small intestinal, urinary bladder channel.Another name is Fructus Toosendan, Fructus Toosendan, Fructus Toosendan are real.For the dry mature fruit of Meliaceae plant Fructus Toosendan, primary medicinal component is Fructus Toosendan element, alkaloid etc.There are soothing liver-QI promoting the circulation of QI to relieve pain, effect of anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.Bitter cold is fallen and is let out, can clearing away liver-fire, let out hot and suffocating, promoting the circulation of QI to relieve pain.
Herba clerodendranthi spicati: sweet in the mouth, bitter in the mouth, cool in nature.For the herb of Labiatae kidney Tea plant kidney tea.Containing triterpenes, flavonoid, volatile oil and other compositions.There is heat clearing away, diuresis, calculus removing effect.For acute and chronic nephritis, cystitis, lithangiuria, cholelithiasis, rheumatic arthritis.
Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.For the dry sclerotia of On Polyporaceae Poria.Have promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieve internal heat anticancer effect.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia, dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, and malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.For the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.There is regulating the flow of QI to ease the stomach, effect of the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, uterine prolapse.
Natrii Sulfas: salty in the mouth, hardship, cold in nature.Return stomach, large intestine channel.For Sulfates mineral Natrii Sulfas race Natrii Sulfas, through the crystalline solid of processing and refining.Main containing aqueous sulfuric acid sodium (Na
2sO
410H
2o).There is purging heat to relax the bowels, moistening for dryness and softening hard mass, the effect of detumescence of relieving inflammation or internal heat.For excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache; External treatment acute mastitis, hemorrhoid tumor.
Herba humuli scandentis: sweet in the mouth, hardship, cold in nature.For the herb of Moraceae humulus plants Herba humuli scandentis.Containing luteolin, glycoside, choline, agedoite and volatilization wet goods.There is heat-clearing and toxic substances removing, effect of inducing diuresis to remove edema.For pulmonary tuberculosis hectic fever, gastroenteritis, dysentery, cold, fever, dysuria, pyelonephritis, acute nephritis, cystitis, urinary system calculus; Carbuncle furuncle and phyma poison is controlled in external, eczema, venom.
test examplein order to verify the curative effect of the Chinese medicinal formulae (embodiment 5) of gained of the present invention treatment cholelithiasis, do contrast test in July ,-2010 in February, 2009:
General data: screening 260 routine Patients with Cholelithiasis, wherein male patient 94 people, female patient 166 people; Minimal ages 23 years old, max age 62 years old, 44.9 years old mean age; 23-40 year 93 people, 41-50 year 94 people, 51-62 year 73 people, be divided into experimental group and matched group two groups (wherein experimental group 160 people at random, matched group 100 people), two groups are compared there was no significant difference (P > 0.05), have comparability in sex, age, the course of disease, state of an illness scoring etc.
Diagnostic criteria: 1. B ultrasonic display gallbladder intracystic stones, thickening of capsule wall of gallbladder, crude, gallbladder volume increase; 2. clinical main manifestations is right flank portion pain, can back porch back of the body radiation to the right, companion's abdominal distention, poor appetite, stomachache or gastric fullness, vexed anxiety etc., also only can not show as right flank portion feeling of distension and oppression discomfort, yellowish urine, lazy tired power, mood smooth etc.
Exclusion standard: 1. have the important organ dysfunction persons such as severe cardiac, liver, kidney; 2. gestation or women breast-feeding their children, allergic constitution person; 3. be associated with severe complication and be badly in need of operative treatment person, as perforation of gallbladder, acute diffuse peritonitis or Acute necrotising pancreatitis etc.; 4. ultrasound diagnosis prompting neck of gallbladder does not obviously block person; 5. Subtotal gastrectomy patient was.
Usage and dosage: experimental group takes the Chinese medicinal formulae granule of gained of the present invention treatment cholelithiasis, each 1 bag, every day 3 times, 2 days courses for the treatment of.Matched group uses other medicine (as DANSHU soft capsule, Ursodeoxycholic Acid Tablets etc.), wherein, and DANSHU soft capsule: oral, a 1-2 grain, 3 times on the one; Or follow the doctor's advice.Ursodeoxycholic Acid Tablets: be grown up oral: every day 8-10mg/kg, early, evening have meal time gradation give.
Criterion of therapeutical effect: cure: the malaise symptoms such as epigastrium pain disappear, B is super to be checked without calculus shade in gallbladder, and gallbladder wall and contractile function recover normal, follow up a case by regular visits to and do not recur for 1 year.Effective: clinical symptoms and sign obviously alleviate, B ultrasonic confirms discharge section calculus, and gallbladder wall and contractile function obviously improve.Invalid: clinical symptoms and sign can have and to alleviate or unchanged, and B is super checks that calculus is without change.
4 courses for the treatment of of medication treatment, observe latter 3 months for the treatment of.The Comparison of therapeutic of the experimental group of the matched group taking other drug and the Chinese medicinal formulae taking gained of the present invention treatment cholelithiasis, result is as shown in table 1:
Table 1
As can be seen from Table 1, take the cure rate of the Chinese medicinal formulae of gained of the present invention treatment cholelithiasis up to 72.5%, effective percentage is up to 98.13%; And the cure rate taking other drug only 43%, effective percentage also only has 80%, and inefficiency is up to 20%.Can find out that successful that the present invention treats the Chinese medicinal formulae of cholelithiasis is better than the effect of other drug significantly.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or obtain undoubtedly according to the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat a Chinese medicinal formulae for cholelithiasis, it is characterized in that, take off the primary raw material stating quality proportioning and be prepared from: Radix Paeoniae Alba 10-13 part; Herba Dianthi 11-13 part; Herba Centipedae 10-13 part; Radix Anemones Rivularis 7-12 part; Fructus Gardeniae 12-18 part; Golden saxifrage 9-12 part; Folium Pyrrosiae 5-7 part; Fructus Toosendan 8-13 part; Herba clerodendranthi spicati 10-13 part; Poria 9-16 part; Fructus Aurantii 10-15 part; Natrii Sulfas 3-5 part; Herba humuli scandentis 9-13 part.
2. Chinese medicinal formulae according to claim 1, is characterized in that, takes off the primary raw material stating quality proportioning and is prepared from: Radix Paeoniae Alba 11-12 part; Herba Dianthi 11.5-12.5 part; Herba Centipedae 11-12 part; Radix Anemones Rivularis 8-11 part; Fructus Gardeniae 14-16 part; Golden saxifrage 10-11 part; Folium Pyrrosiae 5.5-6.5 part; Fructus Toosendan 9-12 part; Herba clerodendranthi spicati 11-12 part; Poria 11-14 part; Fructus Aurantii 11-14 part; Natrii Sulfas 3.5-4.5 part; Herba humuli scandentis 10-12 part.
3. Chinese medicinal formulae according to claim 1, is characterized in that, takes off the primary raw material stating quality proportioning and is prepared from: the Radix Paeoniae Alba 11.5 parts; Herba Dianthi 12 parts; Herba Centipedae 11.5 parts; Radix Anemones Rivularis 9 parts; Fructus Gardeniae 15 parts; Golden saxifrage 10.5 parts; Folium Pyrrosiae 6 parts; Fructus Toosendan 11 parts; Herba clerodendranthi spicati 11.5 parts; 12 parts, Poria; Fructus Aurantii 13 parts; 4 parts, Natrii Sulfas; Herba humuli scandentis 11 parts.
4., according to the arbitrary described Chinese medicinal formulae of claim 1-3, it is characterized in that, the preparation method of described powder, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loading steams in container, airtight, and water proof heating 6-10 hour, takes out, dry, pulverize, excessively 100-140 mesh sieve (preferred 110-130 mesh sieve excessively, was more preferably 120 mesh sieves);
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dry in the air cool, pulverize, excessively 100-140 mesh sieve (preferred 110-130 mesh sieve excessively, was more preferably 120 mesh sieves);
(3) by Natrii Sulfas porphyrize, 100-140 mesh sieve (preferred 110-130 mesh sieve excessively, was more preferably 120 mesh sieves) excessively;
(4) Radix Paeoniae Alba, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis are placed in pot, moderate heat fried dry, pulverize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);
(5) by step (1)-(4) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
5. the preparation method of Chinese medicinal formulae powder according to claim 4, is characterized in that: the consumption of the preferred yellow wine of step (1) is the 20%-40% of Radix Anemones Rivularis quality, and the consumption being more preferably yellow wine is 30% of Radix Anemones Rivularis quality.
6., according to the arbitrary described Chinese medicinal formulae of claim 1-3, it is characterized in that, the preparation method of described decoction, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 40-50 minute, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filters, merging filtrate, be concentrated into 1/2 of original volume, obtain decoction.
7., according to the arbitrary described Chinese medicinal formulae of claim 1-3, it is characterized in that, the preparation method of described pill, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 40-50 minute, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filter, merging filtrate, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste, make pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm).
8., according to the arbitrary described Chinese medicinal formulae of claim 1-3, it is characterized in that, the preparation method of described tablet, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soak 30 minutes, moderate heat decocts 40-50 minute, adds step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filters, merging filtrate, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste, make tablet.
9., according to the arbitrary described Chinese medicinal formulae of claim 1-3, it is characterized in that, the preparation method of described granule, step is as follows:
(1) be placed in glass container by Radix Anemones Rivularis, add yellow wine, mix thoroughly, moistening is sucked to wine, loads and steams in container, airtight, and water proof heating 6-10 hour, takes out, dry;
(2) pot is burnt heat, add Testa Tritici, continue to fry to when smoldering, add Fructus Gardeniae, Fructus Toosendan and Poria, constantly stir, moderate heat fries 30-40 minute, takes out, and sieve removes Testa Tritici, dries in the air cool;
(3) cleaned by the Radix Paeoniae Alba, section, is placed in glass container, adds Chinese liquor (consumption of preferred Chinese liquor is the 10%-15% of Radix Paeoniae Alba quality, and the consumption being more preferably Chinese liquor is 13% of Radix Paeoniae Alba quality), moistening, fried dry;
(4) Natrii Sulfas is placed in marmite, soaks 30 minutes, moderate heat decocts 40-50 minute, add step (1)-(3) gains, Herba Dianthi, Herba Centipedae, golden saxifrage, Folium Pyrrosiae, Herba clerodendranthi spicati, Fructus Aurantii and Herba humuli scandentis, decoct twice, each 30-40 minute, filters, merging filtrate, being concentrated into relative density is 1.10-1.20(25 DEG C) thick paste, add simple syrup, mixing, makes uniform granule, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
10. the preparation method of Chinese medicinal formulae granule according to claim 9, is characterized in that: the consumption of the preferred simple syrup of step (4) is the 5%-7% of thick paste quality, and the consumption being more preferably simple syrup is 6% of thick paste quality.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1879852A (en) * | 2006-04-29 | 2006-12-20 | 赵玉才 | A gall stone-treating medicine |
| CN103585591A (en) * | 2013-11-28 | 2014-02-19 | 唐翔 | Traditional Chinese medicine for treating gallstones |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879852A (en) * | 2006-04-29 | 2006-12-20 | 赵玉才 | A gall stone-treating medicine |
| CN103585591A (en) * | 2013-11-28 | 2014-02-19 | 唐翔 | Traditional Chinese medicine for treating gallstones |
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