CN104740463A - Kidney-nourishing and qi-benefiting medicine for lithangiuria and preparation method of kidney-nourishing and qi-benefiting medicine - Google Patents

Abstract

The invention discloses a kidney-nourishing and qi-benefiting medicine for lithangiuria. The kidney-nourishing and qi-benefiting medicine is prepared from the following raw materials in parts by weight: 9-12 parts of fine licorice roots, 5-10 parts of paeony, 8-12 parts of cortex sclerotii poriae, 10-15 parts of semen lepidii, 8-16 parts of radix stemonae, 9-12 parts of raw oyster shell, 5-12 parts of cyclea polytata, 6-9 parts of radix angelicae, 8-15 parts of processed peach kernel, 6-9 parts of folium citri reticulatae, 6-15 parts of rubia tinctorum madder roots, 9-16 parts of rhizoma atractylodis macrocephalae (fried with earth), 8-16 parts of spreading violet, 4-9 parts of radix cyathulae, 4-9 parts of uncaria rhynchophylla, 4-9 parts of bamboo shavings, 10-15 parts of fructus psoraleae and 6-12 parts of tabasheer (smashed). The kidney-nourishing and qi-benefiting medicine has the excellent effects that the formulation composition is analyzed by the theory of the traditional Chinese medicine; a preparation method of reasonable and stable active components is researched according to the research results of the physicochemical property and the pharmacological action of the components contained in various medicines; and the medicine disclosed by the invention is in supplement each other, has the efficacy of inducing decomposition of calculi, treating stranguria, inducing diuresis and eliminating stagnation, and has a good treatment effect on different degrees of symptoms of kidney stones.

Description

Lithangiuria is tonified Qi of the kidney medicament and preparation method

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of lithangiuria and to tonify Qi of the kidney medicament and preparation method.

Background technology

Lithangiuria is one of modal urological diseases.Lithangiuria is formed at kidney and intravesical.All calculus occurred at human body renal pelvis, ureter, bladder, urethra, are referred to as urinary system calculus, also known as urinary calculus.Urinary calculus is global commonly encountered diseases, and in the change of China along with dietary structure and the change of water quality, its sickness rate has the trend increased year by year.And being mainly in person between twenty and fifty, male is more than women.The symptoms such as common sudden angor, hematuria, dysuria, urine retention, bring huge misery to patient.

Primary disease belongs to motherland's medical science " stranguria caused by urinary stone ", " sand Stranguria ", " stranguria with blood " category.The formation of calculus, motherland's medical science thinks to be the result of the factor effect such as " damp and hot ", " blood stasis ".Functioning of bladder is unfavorable, the damp-heat accumulation part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, and urine decocts by damp and hot, accumulates over a long period, and turbidity is condensed and forms calculus, calculus stasis water channel, and the stasis of blood is stagnant must not let out down, and juice QI-blood circulation is smooth, qi depression to blood stasis, stagnation of QI and blood may bring about pain.Modern medicine study thinks that the principal element of stars duct ligation stone is: (1) epidemiologic factor: comprise the factors such as age, occupation, socioeconomic status, dietary constituents and structure, weather, metabolism and heredity.(2) urine factor: as in urine, calcium, oxalic acid, uric acid output increase; Crystal formation content of material is suppressed to reduce in urine; (3) urinary tract infection etc.Current treatment lithangiuria one adopts Drug therapy, and two is operative treatments, because operative treatment patient trauma is large, easy recurrence, therefore, adopt Drug therapy to be conventional technological means at present, though western medicine energy rapid relief of symptoms, but safety is low, bring larger burden and infringement to the kidney of patient, Chinese medicine lithangiuria can effectively improve calculus elimination factor, shortens calculus efflux time, reduce Relapse rate and can renal function be improved, obtaining extensive promotion and application clinically.

Application publication number CN 103446217 A(application number 201210188921.6) Chinese invention patent document disclose a kind of Chinese medicine for the treatment of lithangiuria, be made up of the component of following weight portion: Herba portulacae 110-130 gram, Flos Lonicerae 50-70 gram, brown sugar 80-100 gram.Application publication number CN 103041199 A(application number 201210558995.4) Chinese invention patent document disclose a kind of Chinese medicine composition for the treatment of lithangiuria, be made up of the crude drug of following weight parts: Fructus Gardeniae 10, the Rhizoma Anemarrhenae 10, Stigma Maydis 15, Folium Pyrrosiae 8, Rhizoma Imperatae 12, Cortex Moutan 12, Fructus Corni 9, Spica Prunellae 9, Semen Plantaginis 8, Radix Clematidis 8, the Radix Linderae 10, Herba Artemisiae Scopariae 6, Radix Achyranthis Bidentatae 6, Radix Angelicae Sinensis 12.Application publication number CN 103550679 A(application number 201310461007.9) Chinese invention patent document disclose a kind of Traditional Chinese medicine formula for treatment of lithangiuria, be made up of the crude drug of following weight: Herba Lysimachiae 60g, Endothelium Corneum Gigeriae Galli 15g, Fructus Crataegi 15g, Rhizoma Curcumae 15g, Radix Paeoniae Rubra 15g, Cortex Moutan 15g, Semen Persicae 10g, Flos Carthami 10g ， Herba Polygoni Avicularis 15g, Semen Plantaginis 15g, Talcum 20g, Radix Glycyrrhizae 6g.

For the patient that calculus is less, western medical treatment generally to drink more water, to jog, jumping exercise is treated to master, effect is also imprecise; For the patient that calculus is larger, be then essential therapeutic arsenals with external stone crushing, somewhat expensive, also can bring wound to health, has certain side effect; Therefore, develop a kind of Chinese traditional treatment method that is safe and effective, non-invasive and have important clinical value.

Summary of the invention

For the deficiencies in the prior art, the object of this invention is to provide that one is prepared simply, taking convenience, safely and effectively lithangiuria tonify Qi of the kidney medicament and preparation method.Curative effect of medicine of the present invention is remarkable and without any side effects, easy to utilize.

Technical scheme of the present invention is:

Lithangiuria is tonified Qi of the kidney medicament, is prepared from, is weight portion: Radix Glycyrrhizae uralensis 9-12 by following bulk drugs; Radix Paeoniae 5-10; Cortex Sclerotii Poriae 8-12; Semen Lepidii (Semen Descurainiae) 10-15; Radix Stemonae 8-16; Concha Ostreae 9-12; Radix Ilicis Asprellae rattan 5-12; Radix Angelicae Dahuricae 6-9; Semen Persicae 8-15 processed; Folium Citri tangerinae 6-9; Radix Rubiae 6-15; The Rhizoma Atractylodis Macrocephalae (parching with earth) 9-16; Herba Violae diffusae 8-16; Radix Cyathulae 4-9; Ramulus Uncariae Cum Uncis 4-9; Caulis Bambusae In Taenia 4-9; Fructus Psoraleae 10-15; Concretio Silicea Bambusae (smashing) 6-12.

In preferred scheme, Radix Glycyrrhizae uralensis 10-11; Radix Paeoniae 6-9; Cortex Sclerotii Poriae 9-11; Semen Lepidii (Semen Descurainiae) 11-14; Radix Stemonae 10-14; Concha Ostreae 10-11; Radix Ilicis Asprellae rattan 7-10; Radix Angelicae Dahuricae 7-8; Semen Persicae 10-13 processed; Folium Citri tangerinae 7-8; Radix Rubiae 8-13; The Rhizoma Atractylodis Macrocephalae (parching with earth) 11-14; Herba Violae diffusae 10-14; Radix Cyathulae 5-8; Ramulus Uncariae Cum Uncis 5-8; Caulis Bambusae In Taenia 5-8; Fructus Psoraleae 11-14; Concretio Silicea Bambusae (smashing) 8-10.

Be more preferably, Radix Glycyrrhizae uralensis 10.5; Radix Paeoniae 7.5; Cortex Sclerotii Poriae 10; Semen Lepidii (Semen Descurainiae) 12.5; The Radix Stemonae 12; Concha Ostreae 10.5; Radix Ilicis Asprellae rattan 8.5; The Radix Angelicae Dahuricae 7.5; Semen Persicae 11.5 processed; Folium Citri tangerinae 7.5; Radix Rubiae 10.5; The Rhizoma Atractylodis Macrocephalae (parching with earth) 12.5; Herba Violae diffusae 12; Radix Cyathulae 6.5; Ramulus Uncariae Cum Uncis 6.5; Caulis Bambusae In Taenia 6.5; Fructus Psoraleae 12.5; Concretio Silicea Bambusae (smashing) 9.

Lithangiuria is tonified Qi of the kidney medicament, and be made into pharmaceutically acceptable decoction, preparation method is as follows:

(1) Semen Lepidii (Semen Descurainiae) is put in frying pan, and slow fire adds to be propagandized hotly to there being detonans, and taking-up cools, and porphyrize is for subsequent use; Concha Ostreae is cleaned, and put on smokeless stove fire and be calcined to canescence, taking-up cools, and pulverizes for subsequent use; Soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, cools, grinds for subsequent use;

(2) Concretio Silicea Bambusae is smashed to pieces, is ground into fine powder, and the crude drug mixing after same step (1) process, sieves, obtain mixing fine powders for subsequent use;

(3) crude drug except Semen Lepidii (Semen Descurainiae), Concha Ostreae, Concretio Silicea Bambusae and the Rhizoma Atractylodis Macrocephalae is placed in extraction pot, add clear water to soak, intense fire is heated to boil, turn slow fire boiling three times, first time decocts 42-60 minute (preferably first time decocts 50 minutes), second time decocts 35-50 minute (preferably second time decocts 42 minutes), third time adds step (2) gained mixing fine powders before decocting, slow fire continues to decoct 22-46 minute (preferred slow fire continues decoction 34 minutes), merge three decocting liquids, cotton cloth filters, and obtains filtrate;

(4) above-mentioned filtrate is concentrated into 1/3 of original volume, sterilizing, cooling, encapsulation, to obtain final product.

Above-mentioned lithangiuria is tonified Qi of the kidney the preparation method of decoction, and preferred scheme is, crosses 70-110 mesh sieve (preferred cross 80-100 mesh sieve, mistake 90 mesh sieve be more preferably) in step (2).

Above-mentioned lithangiuria is tonified Qi of the kidney the preparation method of decoction, and preferred scheme is, adds the clear water (preferably adding the clear water of 7-9 times amount, the clear water adding 8 times amount be more preferably) of 6-10 times amount in step (3).

Above-mentioned lithangiuria is tonified Qi of the kidney the preparation method of decoction, and preferred scheme is, the time of soaking in step (3) is 2-5 hour (the preferred time of soaking is 3-4 hour, and the time of the immersion be more preferably is 3.5 hours).

The preparation method of described thick paste agent is:

(1) get Radix Cyathulae sheet, the saline solution adding 2% is mixed thoroughly, puts in medicine pot, and slow fire heats, fried dry, and taking-up cools, for subsequent use; Soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, cools for subsequent use;

(2) by step (1) process after the same Radix Glycyrrhizae uralensis of crude drug, Radix Paeoniae, Cortex Sclerotii Poriae, the Radix Stemonae, Radix Ilicis Asprellae rattan, the Radix Angelicae Dahuricae, Radix Rubiae, BAICAO, Ramulus Uncariae Cum Uncis and Caulis Bambusae In Taenia be together placed in Chinese medicinal pot, add water and do not have powder, slow fire boiling twice, each respectively decoction 35-55 minute (preferably each each decoction 45 minutes), merge twice decocting liquid, filter, obtain filtrate, for subsequent use;

(3) Fructus Psoraleae, Concretio Silicea Bambusae, Semen Persicae processed, Semen Lepidii (Semen Descurainiae), Concha Ostreae and Folium Citri tangerinae are pulverized respectively, mixing, cross 70-90 mesh sieve (preferred mistake 80 mesh sieve), for subsequent use;

(4) joined in step (2) gained filtrate by step (3) gained raw material medicated powder, being evaporated to 70 DEG C of relative densities is the thick paste of 1.28-1.30, sterilizing, cooling, and encapsulation, to obtain final product.

The preparation method of described capsule is:

(1) soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, smashs to pieces for subsequent use;

(2) surplus stock medicine is placed in air drier, in 40-60 DEG C of dry 50-70 minute (being preferable over 50 DEG C of dryings 60 minutes), is ground into fine powder, for subsequent use;

(3) by step (1) and the mixing of step (2) gained fine powder, cross 100-140 mesh sieve (preferred mistake 120 mesh sieve), add the sucrose fine of 7%, stir, incapsulate shell according to the metering (preferably according to the metering of 0.4 g/ grain) of 0.3-0.5g/ grain, to obtain final product.

The preparation method of described powder is:

(1) soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, smashs to pieces for subsequent use;

(2) surplus stock medicine is placed in air drier, in 40-60 DEG C of dry 50-70 minute (being preferable over 50 DEG C of dryings 60 minutes), is ground into fine powder, for subsequent use;

(3) by step (1) and the mixing of step (2) gained fine powder, cross 60-100 mesh sieve (preferred mistake 80 mesh sieve), be distributed into bag according to the metering (preferably according to the metering of 8 g/ bags) of 5-10g/ bag, obtain final product.

Scientific formula of the present invention, preparation method is simple, easy to use, Be very effective.In addition, excellent results of the present invention also shows:

1,the present invention uses theory of Chinese medical science to analyze prescription composition, and according to each physicochemical property of flavour of a drug ingredient and the result of study of pharmacological action, research obtains the preparation method of reasonable, stable active component;

2,medicine of the present invention supplements and complements each other, and has that fossil is treating stranguria, effect of heat-clearing and toxic substances removing, diuretic eliminating stagnation, all has good therapeutical effect to lithangiuria symptom in various degree;

3,medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Radix Glycyrrhizae uralensis: base is former: be tip part or the radicula of the root of glycyrrhizic legume.Nature and flavor: " Elementary Medicine ": " cold in nature." function cures mainly: relieve inflammation or internal heat, removing toxic substances.Control pain and stranguria with turbid discharge in penis.

Radix Paeoniae: base is former: be the root of Paeoniaceae plant peony, CHUANSHAO medicine, Paeonia obovata Maxim., hair leaf Paeonia obovata Maxim., Paeonia mairei Lévl., Paeonia anomala and tuber Radix Paeoniae.Nature and flavor: bitter, sour, are slightly cold.Gui Jing: return liver, spleen channel.Effect: nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG.

Cortex Sclerotii Poriae: base is former: be the crust of Polyporaceae plant poria cocos sclerotium.Nature and flavor: sweet light are flat.Gui Jing: return: kidney, urinary bladder channel.Function cures mainly: diuretic, detumescence.To harness the river swollen general edema.

Semen Lepidii (Semen Descurainiae): base is former: be the seed of crucifer Lepidium sativum L., North America semolina or descurainia sophia (l.) webb ex prantl.Nature and flavor: arduous, cold.Gui Jing: enter lung, urinary bladder channel.Function cures mainly: therapeutic method to keep the adverse QI flowing downwards row water.Control lung and stop up dyspnea with rapid respiration, expectorant bank is coughed, edema distension.

The Radix Stemonae: base is former: be the tuber of Stemonaceae plant Radix stemonae japonicae, Radix Stemonae or radix stemonae tuberosae etc.Pharmacological action: 1. antibacterial action: during in vitro tests the Radix Stemonae (kind is not identified) decoct and the immersion of radix stemonae tuberosae ethanol to various pathogens as streptococcus pneumoniae, beta hemolysis type streptococcus, meningococcus, staphylococcus aureus, Staphylococcus albus and dysentery bacterium, Bacillus typhi, Salmonella paratyphi, escherichia coli, Bacillus proteus, diphtheria corynebacterium, pneumobacillus, bacillus pestis, anthrax bacillus, bacillus subtilis, and vibrio cholera, Bacillus tuberculosis etc. have bacteriostasis in various degree; 2. insecticidal action: the infusion of Radix stemonae japonicae and other kind of Radix Stemonae (kind is not identified) and ethanol immersion, all has killing action to mosquitos and flies larva, head louse, clothing louse and Cimex bedbug etc.The high concentration Radix Stemonae (kind fail to understand) in vitro and can kill Mus pinworm.Nature and flavor: sweetness and bitterness, tepor.Gui Jing: enter lung meridian.Function cures mainly: gentle lung qi, cough-relieving, parasite killing.Control cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.

Concha Ostreae (Concha Ostreae): base is former: this product is the shell of the long Concha Ostreae of Ostreidae animal, Dalian Bay Concha Ostreae or Crassostrea rivularis.Nature and flavor: salty, are slightly cold.Gui Jing: return liver, gallbladder, kidney channel.Effect: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly: for insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.

Radix Ilicis Asprellae rattan: base is former: be root or the rattan of menispermaceous plants powder vane rings rattan.Nature and flavor: bitter; Cold.Gui Jing: lung; Large intestine; Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Wind-expelling pain-stopping; Relieving stranguria by diuresis.Main anemopyretic cold; Cough; Laryngopharynx swelling and pain; Diphtheria; Acute toothache; Intestinal is scorching; Dysentery; Urinary tract infection and lithangiuria; Rheumatalgia; Sore swollen toxin; Venom.

The Radix Angelicae Dahuricae: base is former: be the root of samphire Angelica dahurica, angelica anomala, Radix angelicae dahuricae or Yunnan cattle Radix Saposhnikoviae.Chemical analysis: containing isoimperatorin, imperatorin, bergapton, phellopterin, oxypeucedanin etc.Nature and flavor: pungent, temperature.Gui Jing: enter lung, thigh, stomach warp.Function cures mainly: dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.

Semen Persicae processed: preparation method: Semen Persicae removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean.Nature and flavor: bitter, sweet, flat.Gui Jing: enter the heart, liver, large intestine channel.Function cures mainly: blood stasis removing and clots absorbing, moisturizes laxation.Control amenorrhea, lump in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.

Folium Citri tangerinae: source: be the leaf of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae.Character: dried leaves multireel contracts, in Pedicellus et Pericarpium Trapae shape oblong or ellipse after open and flat, surperficial celadon or yellow green, smooth, can according to seeing numerous transparent glandule points to light.Nature and flavor: toil are flat.Gui Jing: Zhu Zhenheng: " enter liver channel of foot-Jueyin edema caused by disorder of QI." function cures mainly: soothing the liver, circulation of qi promoting, reduces phlegm, detumescence poison.Control hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.

Radix Rubiae: base is former: be the root and rhizome of Maguireothamnus speciosus Radix Rubiae.Chemical analysis: the root of Radix Rubiae is containing purple alizarin, alizarin, psedopurpurin, madder color.Pharmacological action: 1. cough-relieving, phlegm-dispelling functions; 2. to the effect of smooth muscle: to isolated rabbit ileum, Radix Rubiae decoct can to the contraction of anti-acetylcholine.Nature and flavor: bitter, cold.Gui Jing: enter the heart.Liver Channel.Function cures mainly: promoting the circulation of blood is stopped blooding, dredge the meridian passage, eliminating phlegm and stopping cough.Control haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, rheumatic arthralgia, traumatic injury, the stasis of blood is stagnant to swell and ache, jaundice, chronic tracheitis.

The Rhizoma Atractylodis Macrocephalae: base is former: this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Chemical analysis: containing volatile oil 1.4%, main component is atractylol, atractylone etc., and containing vitamin A.Nature and flavor: bitter, sweet, temperature.Gui Jing: return spleen, stomach warp.Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.Cure mainly: for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.

Herba Violae diffusae: base is former: be the herb of Jian Cai section plant Climbing Viloet Herb.Nature and flavor: bitter, cold.Function cures mainly: dispel the wind, heat clearing away, diuresis, removing toxic substances.Control cough due to pathogenic wind-heat, dysentery, stranguria with turbid discharge, carbuncle sore tumefacting virus, blepharitis, scald.

Radix Cyathulae: base is former: this product is the dry root of amaranthaceous plant Radix Cyathulae.Character: this product is in closely cylindrical, and micro-distortion, omits thin downwards or have minority branch.Surface yellowish-brown or taupe, tool indulges the hole skin of wrinkle, supporting root trace and most transverse projections.Nature and flavor: sweet, micro-hardship are flat.Gui Jing: return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Cure mainly: for amenorrhea carcinoma, retention of placenta, arthralgia, sufficient health clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.

Ramulus Uncariae Cum Uncis: base is former: be Maguireothamnus speciosus Ramulus Uncariae Cum Uncis or Uncaria sinensis (Oliv.) Havil. and the buckle branch belonging to various plants together thereof.Chemical analysis: stem and branch with belt hook leaf is containing Ramulus Uncariae cum Uncis alkali, isorhynchophylline, corynoxeine, different corynoxeine, corynantheine alkali, dihydrocorynantheine alkali, hirsutine, hirsuteine.Nature and flavor: sweet are cool.Gui Jing: enter liver, heart channel.Pharmacological action: 1. sedation; 2. hypotensive effect.Function cures mainly: heat clearing away suppressing the hyperactive liver, and relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Control pediatric epilepsy scared Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclamposia.

Caulis Bambusae In Taenia: base is former: this product is the dry intermediate layer of stem stalk of grass bambusa breviflora Munro, major part allusion quotation bamboo or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.Character: this product is curling agglomerating irregular strand or elongated flake.Nature and flavor: sweet, are slightly cold.Gui Jing: attach to the lung and stomach meridians.Effect: removing heat-phlegm, relieves restlessness and prevents vomiting.Curing mainly: for phlegm-heat cough. expectorant held under the arm by gallbladder fire, and dysphoria with smothery sensation is vomitted, palpitation with fear insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.

Fructus Psoraleae: base is former: be the fruit of legumes psoraleae.Chemical analysis: fruit is containing volatile oil about 20%, organic acid, a kind of methyl glucoside, alkali soluble resins, fixedness terpenoid oil, Saponin.Seed containing Coumarins psoralen and isopsorapen altogether about 1.1%, flavonoid bavachin, bavachinin, isobavachin and chalcone Bavachalcone, corylifolinin, monoterpene amphyl Bakuchiol; Still containing volatile oil, resin, fatty oil.Spend fatty oil, volatile oil, sterol, alkaloid etc.This plant is also containing Raffinose.Nature and flavor: pungent, temperature.Gui Jing: enter kidney channel.Function cures mainly: reinforcing the kidney and supporting YANG.Control cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and is coughed.External curing vitiligo.

Concretio Silicea Bambusae: base is former: this product is the dried block of juice in the stalk such as grass Chinese textile bamboo or schizostachyum chinense Rendle.Character: this product is irregular fast or granule, not of uniform size.Surface dusty blue, lark or canescence, the pure white color had, translucent, slightly gloss.Body is light, and matter is hard and crisp, and easily broken, hygroscopicity is strong.Feeble QI, lightly seasoned.Nature and flavor: sweet, cold.Gui Jing: GUIXIN, Liver Channel.Effect: clear heat and eliminate phlegm, cool heart arresting convulsion.Cure mainly: for calentura coma, middle wind-phlegm fan, the hot diarrhea induced by fright of children's's expectorant, tic, night cry.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.

embodiment 1lithangiuria is tonified Qi of the kidney medicament, is prepared from, is weight portion (80g/ part): Radix Glycyrrhizae uralensis 9 parts by following bulk drugs; Radix Paeoniae 5 parts; Cortex Sclerotii Poriae 8 parts; Semen Lepidii (Semen Descurainiae) 10 parts; The Radix Stemonae 8 parts; Concha Ostreae 9 parts; 5 parts, Radix Ilicis Asprellae rattan; The Radix Angelicae Dahuricae 6 parts; 8 parts, Semen Persicae processed; Folium Citri tangerinae 6 parts; Radix Rubiae 6 parts; The Rhizoma Atractylodis Macrocephalae (parching with earth) 9 parts; Herba Violae diffusae 8 parts; Radix Cyathulae 4 parts; Ramulus Uncariae Cum Uncis 4 parts; Caulis Bambusae In Taenia 4 parts; Fructus Psoraleae 10 parts; Concretio Silicea Bambusae (smashing) 6 parts.

The tonify Qi of the kidney preparation method of decoction of above-mentioned lithangiuria is:

(1) Semen Lepidii (Semen Descurainiae) is put in frying pan, and slow fire adds to be propagandized hotly to there being detonans, and taking-up cools, and porphyrize is for subsequent use; Concha Ostreae is cleaned, and put on smokeless stove fire and be calcined to canescence, taking-up cools, and pulverizes for subsequent use; Soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, cools, grinds for subsequent use;

(2) Concretio Silicea Bambusae is smashed to pieces, is ground into fine powder, and the crude drug mixing after same step (1) process, crosses 70 mesh sieves, obtain mixing fine powders for subsequent use;

(3) crude drug except Semen Lepidii (Semen Descurainiae), Concha Ostreae, Concretio Silicea Bambusae and the Rhizoma Atractylodis Macrocephalae is placed in extraction pot, the clear water adding 6 times amount soaks 2 hours, intense fire is heated to boil, and turns slow fire boiling three times, and first time decocts 42 minutes, second time decocts 35 minutes, third time adds step (2) gained mixing fine powders before decocting, and slow fire continues decoction 22 minutes, merges three decocting liquids, cotton cloth filters, and obtains filtrate;

(4) above-mentioned filtrate is concentrated into 1/3 of original volume, sterilizing, cooling, encapsulation, to obtain final product.

The instructions of taking of decoction of the present invention is: twice daily, each 80-100mL, warmly takes, 7 days courses for the treatment of.

Model case: Liu XX, female, 39 years old, certain institute researcher.Patient is to our hospital on July 11st, 2011.Patient's readme: occurred lumbago symptom without obvious inducement before 5 months, once in local hospital inspection, blood test is conventional, renal function is all normal, does not carry out systematic treating.Patient's lumbago aggravation two months ago, companion frequent micturition, dysurea symptom.Come my institute to check: patient's lumbago, when drowning, puckery pain unbearably; Pouring drop is not well, yellowish fur, stringy and rolling pulse; Routine urinalysis: occult blood (+), calcium oxalate crystal 3+/HP, urine creatine 4106umol/L, plain abdominal radiograph prompting has calculus.Be diagnosed as renal calculus.

Take the present embodiment gained lithangiuria to tonify Qi of the kidney decoction, instructions of taking: twice daily, each 80-100mL, warmly to take, 7 days courses for the treatment of.After treating a course for the treatment of, lumbago obviously alleviates, and plain abdominal radiograph prompting calculus moves down; Continue two courses for the treatment of of medication, patient discharges calculus smoothly, and other symptoms all disappear, and patient's self-induction is fully recovered.Pay a return visit after three months, without recurrence.

embodiment 2lithangiuria is tonified Qi of the kidney medicament, is prepared from, is weight portion (60g/ part): Radix Glycyrrhizae uralensis 12 parts by following bulk drugs; Radix Paeoniae 10 parts; Cortex Sclerotii Poriae 12 parts; Semen Lepidii (Semen Descurainiae) 15 parts; The Radix Stemonae 16 parts; Concha Ostreae 12 parts; 12 parts, Radix Ilicis Asprellae rattan; The Radix Angelicae Dahuricae 9 parts; 15 parts, Semen Persicae processed; Folium Citri tangerinae 9 parts; Radix Rubiae 15 parts; The Rhizoma Atractylodis Macrocephalae (parching with earth) 16 parts; Herba Violae diffusae 16 parts; Radix Cyathulae 9 parts; Ramulus Uncariae Cum Uncis 9 parts; Caulis Bambusae In Taenia 9 parts; Fructus Psoraleae 15 parts; Concretio Silicea Bambusae (smashing) 12 parts.

The tonify Qi of the kidney preparation method of thick paste agent of above-mentioned lithangiuria is:

(1) get Radix Cyathulae sheet, the saline solution adding 2% is mixed thoroughly, puts in medicine pot, and slow fire heats, fried dry, and taking-up cools, for subsequent use; Soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, cools for subsequent use;

(2) by step (1) process after the same Radix Glycyrrhizae uralensis of crude drug, Radix Paeoniae, Cortex Sclerotii Poriae, the Radix Stemonae, Radix Ilicis Asprellae rattan, the Radix Angelicae Dahuricae, Radix Rubiae, BAICAO, Ramulus Uncariae Cum Uncis and Caulis Bambusae In Taenia be together placed in Chinese medicinal pot, add water and do not have powder, slow fire boiling twice, each each decoction 45 minutes, merge twice decocting liquid, filter, obtain filtrate, for subsequent use;

(3) Fructus Psoraleae, Concretio Silicea Bambusae, Semen Persicae processed, Semen Lepidii (Semen Descurainiae), Concha Ostreae and Folium Citri tangerinae are pulverized respectively, mixing, cross 80 mesh sieves, for subsequent use;

(4) joined in step (2) gained filtrate by step (3) gained raw material medicated powder, being evaporated to 70 DEG C of relative densities is the thick paste of 1.28-1.30, sterilizing, cooling, and encapsulation, to obtain final product.

The instructions of taking of thick paste agent of the present invention is: every day three times, get 2-3 soupspoon, warm water is taken after mixing it with water at every turn, 7 days courses for the treatment of.

embodiment 3lithangiuria is tonified Qi of the kidney medicament, is prepared from, is weight portion (75g/ part): Radix Glycyrrhizae uralensis 10 parts by following bulk drugs; Radix Paeoniae 6 parts; Cortex Sclerotii Poriae 9 parts; Semen Lepidii (Semen Descurainiae) 11 parts; The Radix Stemonae 10 parts; Concha Ostreae 10 parts; 7 parts, Radix Ilicis Asprellae rattan; The Radix Angelicae Dahuricae 7 parts; 10 parts, Semen Persicae processed; Folium Citri tangerinae 7 parts; Radix Rubiae 8 parts; The Rhizoma Atractylodis Macrocephalae (parching with earth) 11 parts; Herba Violae diffusae 10 parts; Radix Cyathulae 5 parts; Ramulus Uncariae Cum Uncis 5 parts; Caulis Bambusae In Taenia 5 parts; Fructus Psoraleae 11 parts; Concretio Silicea Bambusae (smashing) 8 parts.

The tonify Qi of the kidney preparation method of capsule of above-mentioned lithangiuria is:

(1) soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, smashs to pieces for subsequent use;

(2) surplus stock medicine is placed in air drier, in 50 DEG C of dryings 60 minutes, is ground into fine powder, for subsequent use;

(3) by step (1) and the mixing of step (2) gained fine powder, cross 120 mesh sieves, add the sucrose fine of 7%, stir, incapsulate shell according to the metering of 0.4 g/ grain, to obtain final product.

The instructions of taking of gained capsule of the present invention is: every day three times, each 4-6 grain, and warm water takes, 7 days courses for the treatment of.

embodiment 4lithangiuria is tonified Qi of the kidney medicament, is prepared from, is weight portion (65g/ part): Radix Glycyrrhizae uralensis 11 parts by following bulk drugs; Radix Paeoniae 9 parts; Cortex Sclerotii Poriae 11 parts; Semen Lepidii (Semen Descurainiae) 14 parts; The Radix Stemonae 14 parts; Concha Ostreae 11 parts; 10 parts, Radix Ilicis Asprellae rattan; The Radix Angelicae Dahuricae 8 parts; 13 parts, Semen Persicae processed; Folium Citri tangerinae 8 parts; Radix Rubiae 13 parts; The Rhizoma Atractylodis Macrocephalae (parching with earth) 14 parts; Herba Violae diffusae 14 parts; Radix Cyathulae 8 parts; Ramulus Uncariae Cum Uncis 8 parts; Caulis Bambusae In Taenia 8 parts; Fructus Psoraleae 14 parts; Concretio Silicea Bambusae (smashing) 10 parts.

The tonify Qi of the kidney preparation method of powder of above-mentioned lithangiuria is:

(1) soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, smashs to pieces for subsequent use;

(2) surplus stock medicine is placed in air drier, in 50 DEG C of dryings 60 minutes, is ground into fine powder, for subsequent use;

(3) by step (1) and the mixing of step (2) gained fine powder, cross 80 mesh sieves, enter bag according to the metering, distributing, packaging of 8 g/ bags, to obtain final product.

The instructions of taking of gained powder of the present invention is: twice daily, each 1-2 bag, and hot water is taken after mixing it with water, 7 days courses for the treatment of.

Model case a: XX, man, 46 years old, workman.Patient is to our hospital on May 11st, 2012.Patient's readme: occurred right lower abdomen pain without obvious inducement before one month, dysuria, once carried out anti-inflammatory treatment in local institute, DeGrain, introduces my institute afterwards check medical through friend.Check: patient's right lower abdomen pain is obvious, and frequent micturition is short red, drench drop not well, yellowish fur, stringy and rolling pulse.Lab testing: the light tenderness in ureter traveling district, right side, Shuan Shen district is not full, and waist costal fovea exists, and kidney does not touch, and You Shen district tapping pain, is diagnosed as ureteral calculus through x-ray and ultrasound diagnosis.

Take the present embodiment gained lithangiuria to tonify Qi of the kidney powder, instructions of taking: twice daily, each 1-2 bag, hot water is taken after mixing it with water, 7 days courses for the treatment of.After taking a course for the treatment of, patient pain alleviates, and calculus reduces obviously before comparatively treating, and continues two courses for the treatment of of medication, checks and finds that calculus disappears, and other symptoms and sign are eliminated, and patient fully recovers.

embodiment 5lithangiuria is tonified Qi of the kidney medicament, is prepared from, is weight portion (70g/ part): Radix Glycyrrhizae uralensis 10.5 parts by following bulk drugs; Radix Paeoniae 7.5 parts; Cortex Sclerotii Poriae 10 parts; Semen Lepidii (Semen Descurainiae) 12.5 parts; The Radix Stemonae 12 parts; Concha Ostreae 10.5 parts; 8.5 parts, Radix Ilicis Asprellae rattan; The Radix Angelicae Dahuricae 7.5 parts; 11.5 parts, Semen Persicae processed; Folium Citri tangerinae 7.5 parts; Radix Rubiae 10.5 parts; The Rhizoma Atractylodis Macrocephalae (parching with earth) 12.5 parts; Herba Violae diffusae 12 parts; Radix Cyathulae 6.5 parts; Ramulus Uncariae Cum Uncis 6.5 parts; Caulis Bambusae In Taenia 6.5 parts; Fructus Psoraleae 12.5 parts; Concretio Silicea Bambusae (smashing) 9 parts.

The tonify Qi of the kidney preparation method of decoction of above-mentioned lithangiuria is:

(1) Semen Lepidii (Semen Descurainiae) is put in frying pan, and slow fire adds to be propagandized hotly to there being detonans, and taking-up cools, and porphyrize is for subsequent use; Concha Ostreae is cleaned, and put on smokeless stove fire and be calcined to canescence, taking-up cools, and pulverizes for subsequent use; Soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, cools, grinds for subsequent use;

(2) Concretio Silicea Bambusae is smashed to pieces, is ground into fine powder, and the crude drug mixing after same step (1) process, crosses 90 mesh sieves, obtain mixing fine powders for subsequent use;

(3) crude drug except Semen Lepidii (Semen Descurainiae), Concha Ostreae, Concretio Silicea Bambusae and the Rhizoma Atractylodis Macrocephalae is placed in extraction pot, the clear water adding 8 times amount soaks 3.5 hours, intense fire is heated to boil, and turns slow fire boiling three times, and first time decocts 50 minutes, second time decocts 42 minutes, third time adds step (2) gained mixing fine powders before decocting, and slow fire continues decoction 34 minutes, merges three decocting liquids, cotton cloth filters, and obtains filtrate;

(4) above-mentioned filtrate is concentrated into 1/3 of original volume, sterilizing, cooling, encapsulation, to obtain final product.

The instructions of taking of decoction of the present invention is: twice daily, each 80-100mL, warmly takes, 7 days courses for the treatment of.

test example 1gained lithangiuria of the present invention is tonified Qi of the kidney the clinical practice of medicament (embodiment 5):

1. data and method

1.1 physical data

In November ,-2013 in May, 2010, screen 346 routine patients in 5 hospitals, wherein male 210 example, women 136 example, the age 18-59 year, 42.5 years old mean age; Patient's course of disease was at 7 days-2 months.All patients all make a definite diagnosis the lithangiuria suffered from various degree through x-ray, B ultrasonic or plain abdominal radiograph.Wherein renal calculus 127 example, ureteral calculus 100 example, vesical calculus 53 example, calculus of urethra 66 example.

1.2 diagnostic criteria

(1) Western medicine diagnose standard:

The kidney having typical case to break out or ureteral colic, companion's naked eyes or microscopic hematuria; Or have waist and belly dull pain, sour swollen discomfort; The symptom such as dysuria, urine retention; Uroscopy: urine R-RBC increases, and accompanying infection is visible more leukocyte or pus cell; Imaging examination: B ultrasonic, x-ray or endoscopy show calculus to be existed.

(2) tcm diagnosis standard:

Card is shown in that lumbago, few abdomen are anxious full, and frequent micturition is short red, and when drowning, puckery pain unbearably; Pouring drop is not well, or fever with aversion to cold, yellowish fur, stringy and rolling pulse.

1.3 Therapeutic Method

All patients are divided into experimental group and matched group at random, and two groups of patients, in age, the state of an illness, calculus size etc., through statistical procedures no significant difference (P > 0.05), have comparability.Experimental group is taken gained lithangiuria of the present invention and to be tonified Qi of the kidney decoction, instructions of taking: twice daily, each 80-100mL, warmly takes, 7 days courses for the treatment of.Matched group uses other drug (as medicines such as PAISHI KELI, SHILINTONG PIAN and uralyts).Observe three courses for the treatment of of treatment altogether.

1.4 curative effect determinate standard

Recovery from illness: calculus is discharged, and collects calculus specimen, check B ultrasonic, plain abdominal radiograph, calculus shade disappears; Effective: though calculus does not move, B ultrasonic and plain abdominal radiograph are observed continuously, and calculus diminishes or cracking Fragmentation Phenomena appears in calculus; Invalid: calculus is without movement, and size is without change.(total effective rate=cure rate+effective percentage)

1.5 therapeutic outcome

Two groups of therapeutic outcomes are as shown in table 1.

Table 1: take two groups of patient treatment outcome after this product

Therapeutic effect: cure 151 examples (73.3%), effective 52 examples (25.2%), invalid 3 examples (1.5%), total effective rate is 98.5%, and treatment group successful is better than matched group.

The present invention select Radix Glycyrrhizae uralensis, Radix Paeoniae, Cortex Sclerotii Poriae, Semen Lepidii (Semen Descurainiae), the Radix Stemonae, Concha Ostreae, Radix Ilicis Asprellae rattan, the Radix Angelicae Dahuricae, Semen Persicae processed, Folium Citri tangerinae, Radix Rubiae, the Rhizoma Atractylodis Macrocephalae, Herba Violae diffusae and Radix Cyathulae etc. totally 18 taste primary raw material medicines be prepared from.Fang Zhong, Radix Glycyrrhizae uralensis, Radix Ilicis Asprellae rattan have effect of Qinghuo Jiedu; Cortex Sclerotii Poriae, Radix Angelicae Dahuricae inducing diuresis to remove edema; Semen Lepidii (Semen Descurainiae) therapeutic method to keep the adverse QI flowing downwards row water; The antibacterial insecticidal action of the Radix Stemonae is remarkable; The nourishing YIN of Concha Ostreae YANG hyperactivity suppressing, hard masses softening and resolving; Folium Citri tangerinae is soothing the liver, circulation of qi promoting; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic; Radix Cyathulae easing joint movement, inducing diuresis for treating stranguria syndrome.All medicines share, and play the effects such as fossil is treating stranguria, heat-clearing and toxic substances removing, diuretic eliminating stagnation altogether.After treating three courses for the treatment of, treatment group total effective rate is 98.5%, and matched group is 78.6%.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. lithangiuria is tonified Qi of the kidney medicament, it is characterized in that, is prepared from by following bulk drugs, be weight portion: Radix Glycyrrhizae uralensis 9-12; Radix Paeoniae 5-10; Cortex Sclerotii Poriae 8-12; Semen Lepidii (Semen Descurainiae) 10-15; Radix Stemonae 8-16; Concha Ostreae 9-12; Radix Ilicis Asprellae rattan 5-12; Radix Angelicae Dahuricae 6-9; Semen Persicae 8-15 processed; Folium Citri tangerinae 6-9; Radix Rubiae 6-15; The Rhizoma Atractylodis Macrocephalae (parching with earth) 9-16; Herba Violae diffusae 8-16; Radix Cyathulae 4-9; Ramulus Uncariae Cum Uncis 4-9; Caulis Bambusae In Taenia 4-9; Fructus Psoraleae 10-15; Concretio Silicea Bambusae (smashing) 6-12.

2. lithangiuria as claimed in claim 1 is tonified Qi of the kidney medicament, it is characterized in that, is prepared from by following bulk drugs, be weight portion: Radix Glycyrrhizae uralensis 10-11; Radix Paeoniae 6-9; Cortex Sclerotii Poriae 9-11; Semen Lepidii (Semen Descurainiae) 11-14; Radix Stemonae 10-14; Concha Ostreae 10-11; Radix Ilicis Asprellae rattan 7-10; Radix Angelicae Dahuricae 7-8; Semen Persicae 10-13 processed; Folium Citri tangerinae 7-8; Radix Rubiae 8-13; The Rhizoma Atractylodis Macrocephalae (parching with earth) 11-14; Herba Violae diffusae 10-14; Radix Cyathulae 5-8; Ramulus Uncariae Cum Uncis 5-8; Caulis Bambusae In Taenia 5-8; Fructus Psoraleae 11-14; Concretio Silicea Bambusae (smashing) 8-10.

3. lithangiuria as claimed in claim 1 is tonified Qi of the kidney medicament, it is characterized in that, is prepared from by following bulk drugs, be weight portion: Radix Glycyrrhizae uralensis 10.5; Radix Paeoniae 7.5; Cortex Sclerotii Poriae 10; Semen Lepidii (Semen Descurainiae) 12.5; The Radix Stemonae 12; Concha Ostreae 10.5; Radix Ilicis Asprellae rattan 8.5; The Radix Angelicae Dahuricae 7.5; Semen Persicae 11.5 processed; Folium Citri tangerinae 7.5; Radix Rubiae 10.5; The Rhizoma Atractylodis Macrocephalae (parching with earth) 12.5; Herba Violae diffusae 12; Radix Cyathulae 6.5; Ramulus Uncariae Cum Uncis 6.5; Caulis Bambusae In Taenia 6.5; Fructus Psoraleae 12.5; Concretio Silicea Bambusae (smashing) 9.

4. the lithangiuria as described in as arbitrary in claim 1-3 is tonified Qi of the kidney medicament, and it is characterized in that, be made into pharmaceutically acceptable decoction, preparation method is as follows:

(1) Semen Lepidii (Semen Descurainiae) is put in frying pan, and slow fire adds to be propagandized hotly to there being detonans, and taking-up cools, and porphyrize is for subsequent use; Concha Ostreae is cleaned, and put on smokeless stove fire and be calcined to canescence, taking-up cools, and pulverizes for subsequent use; Soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, cools, grinds for subsequent use;

(2) Concretio Silicea Bambusae is smashed to pieces, is ground into fine powder, and the crude drug mixing after same step (1) process, sieves, obtain mixing fine powders for subsequent use;

(3) crude drug except Semen Lepidii (Semen Descurainiae), Concha Ostreae, Concretio Silicea Bambusae and the Rhizoma Atractylodis Macrocephalae is placed in extraction pot, add clear water to soak, intense fire is heated to boil, turn slow fire boiling three times, first time decocts 42-60 minute (preferably first time decocts 50 minutes), second time decocts 35-50 minute (preferably second time decocts 42 minutes), third time adds step (2) gained mixing fine powders before decocting, slow fire continues to decoct 22-46 minute (preferred slow fire continues decoction 34 minutes), merge three decocting liquids, cotton cloth filters, and obtains filtrate;

(4) above-mentioned filtrate is concentrated into 1/3 of original volume, sterilizing, cooling, encapsulation, to obtain final product.

5. lithangiuria according to claim 4 is tonified Qi of the kidney the preparation method of decoction, it is characterized in that, crosses 70-110 mesh sieve (preferred cross 80-100 mesh sieve, mistake 90 mesh sieve be more preferably) in step (2).

6. lithangiuria according to claim 4 is tonified Qi of the kidney the preparation method of decoction, it is characterized in that, adds the clear water (preferably adding the clear water of 7-9 times amount, the clear water adding 8 times amount be more preferably) of 6-10 times amount in step (3).

7. lithangiuria according to claim 4 is tonified Qi of the kidney the preparation method of decoction, it is characterized in that, the time of soaking in step (3) is 2-5 hour (the preferred time of soaking is 3-4 hour, and the time of the immersion be more preferably is 3.5 hours).

8. the lithangiuria as described in as arbitrary in claim 1-3 is tonified Qi of the kidney medicament, and it is characterized in that, be made into pharmaceutically acceptable thick paste agent, preparation method is as follows:

(1) get Radix Cyathulae sheet, the saline solution adding 2% is mixed thoroughly, puts in medicine pot, and slow fire heats, fried dry, and taking-up cools, for subsequent use; Soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, cools for subsequent use;

(2) by step (1) process after the same Radix Glycyrrhizae uralensis of crude drug, Radix Paeoniae, Cortex Sclerotii Poriae, the Radix Stemonae, Radix Ilicis Asprellae rattan, the Radix Angelicae Dahuricae, Radix Rubiae, BAICAO, Ramulus Uncariae Cum Uncis and Caulis Bambusae In Taenia be together placed in Chinese medicinal pot, add water and do not have powder, slow fire boiling twice, each respectively decoction 35-55 minute (preferably each each decoction 45 minutes), merge twice decocting liquid, filter, obtain filtrate, for subsequent use;

(3) Fructus Psoraleae, Concretio Silicea Bambusae, Semen Persicae processed, Semen Lepidii (Semen Descurainiae), Concha Ostreae and Folium Citri tangerinae are pulverized respectively, mixing, cross 70-90 mesh sieve (preferred mistake 80 mesh sieve), for subsequent use;

(4) joined in step (2) gained filtrate by step (3) gained raw material medicated powder, being evaporated to 70 DEG C of relative densities is the thick paste of 1.28-1.30, sterilizing, cooling, and encapsulation, to obtain final product.

9. the lithangiuria as described in as arbitrary in claim 1-3 is tonified Qi of the kidney medicament, and it is characterized in that, be made into pharmaceutically acceptable capsule, preparation method is as follows:

(1) soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, smashs to pieces for subsequent use;

(2) surplus stock medicine is placed in air drier, in 40-60 DEG C of dry 50-70 minute (being preferable over 50 DEG C of dryings 60 minutes), is ground into fine powder, for subsequent use;

(3) by step (1) and the mixing of step (2) gained fine powder, cross 100-140 mesh sieve (preferred mistake 120 mesh sieve), add the sucrose fine of 7%, stir, incapsulate shell according to the metering (preferably according to the metering of 0.4 g/ grain) of 0.3-0.5g/ grain, to obtain final product.

10. the lithangiuria as described in as arbitrary in claim 1-3 is tonified Qi of the kidney medicament, and it is characterized in that, be made into pharmaceutically acceptable powder, preparation method is as follows:

(1) soil is placed in medicine pot, moderate heat heats, and after making popular, adds Rhizoma Atractylodis Macrocephalae sheet, and when frying to Rhizoma Atractylodis Macrocephalae Wai Jiao Neihuang County, take out, sieve removes soil, smashs to pieces for subsequent use;

(2) surplus stock medicine is placed in air drier, in 40-60 DEG C of dry 50-70 minute (being preferable over 50 DEG C of dryings 60 minutes), is ground into fine powder, for subsequent use;

(3) by step (1) and the mixing of step (2) gained fine powder, cross 60-100 mesh sieve (preferred mistake 80 mesh sieve), be distributed into bag according to the metering (preferably according to the metering of 8 g/ bags) of 5-10g/ bag, obtain final product.