CN104694310A - Grape wine with lipid lowering effect - Google Patents

Grape wine with lipid lowering effect Download PDF

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CN104694310A
CN104694310A CN201510125441.9A CN201510125441A CN104694310A CN 104694310 A CN104694310 A CN 104694310A CN 201510125441 A CN201510125441 A CN 201510125441A CN 104694310 A CN104694310 A CN 104694310A
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fat
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reducing effect
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CN104694310B (en
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孙燕霞
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Hubei Chang'e Biological Co ltd
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G1/00Preparation of wine or sparkling wine

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Abstract

The invention discloses grape wine with a lipid lowering effect. The grape wine is mainly formed by, by mass, 4-9 parts of semen descurainiae, 5-10 parts of lignum dalbergiae odorifereae, 3-8 parts of radix curcumae, 6-11 parts of lily, 8-12 parts of apricots and 340-520 parts of grapes. The grape wine has the effects of promoting qi to activate blood, nourishing yin and moistening the lungs, is safe and free from side effects and can adjust the body function when drunk for a long term.

Description

A kind of grape wine with fat-reducing effect
Technical field
The present invention relates to field of grape wine, particularly relate to a kind of grape wine with fat-reducing effect.
Background technology
Grape wine refers to that form through all or part of fermentation brew, alcoholic strength is more than or equal to the alcoholic beverages of 7% with grape or Sucus Vitis viniferae for raw material.Show through medical research: the nutrition of grape is very high, and be that the grape wine of raw material has also contained multiple amino acids, minerals and vitamins with grape, these materials are all the nutritious prod that human body must supplement and absorb.The composition useful to human body contained in known grape wine approximately just has 600 kinds.Nutritive value vinous have also been obtained thus to be approved widely.
Publication No. CN 104232391 A(application number 201410512781.2) Chinese patent literature disclose a kind of hypertension and hyperlipemia grape wine and preparation method thereof, this grape wine is made up of following raw material by weight ratio: fresh grape 85-95 part, yeast 7-9 part, white sugar 15-30 part, fresh ginger 20-40 part, head of garlic 20-35 part, Semen Cassiae 15-20 part.Publication No. CN 103409267 A(application number 201310343300.5) Chinese patent literature disclose a kind of health wine, be prepared from by the raw material of following weight part: grape wine 500 ~ 1000 parts, hawthorn extract 200 ~ 450 parts, chrysanthemum 50 ~ 100 parts, Chinese traditional medicines depressing lipid liquid 150 ~ 300 parts, sweeting agent 90 ~ 200 parts.Publication No. CN 104293552 A(application number 201410496535.2) Chinese patent literature disclose a kind of fat-reducing grape wine and preparation method thereof; It is combined by grape wine, Stigma Maydis, Cortex Clausenae Excavatae fruit, Rose, Rhizoma Sparganii and Gorgon fruit to make, there is make grape wine except itself all health-care effect, have more Weight-reducing and lipid-lowering, tonifying spleen reinforced the kidney, help the puckery essence of gas, the stasis of blood of dispelling is stimulated the menstrual flow, broken blood eliminating mass, promoting the circulation of qi disappear long-pending, spleen-and-stomach-invigorating, hypoglycemic, reducing blood-fat and the various health care functions such as hypotensive, and taste flavor is special, the demand of different market and crowd can be met.
Current people are with growth in the living standard, more and more pay attention to health and health care, grape wine becomes an indispensable part, but its single health-care effect can not satisfy the demands, therefore should strengthen research in this respect, strive for the grape wine developing more effects.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the wide a kind of grape wine with fat-reducing effect of safe and applicable.
Technical scheme of the present invention is:
There is a grape wine for fat-reducing effect, be prepared from primarily of following raw materials according, be mass parts: Semen Lepidii (Semen Descurainiae) 4-9; Dalbergia wood 5-10; Root tuber of aromatic turmeric 3-8; Lily 6-11; Almond 8-12; Grape wine 340-520.
Preferred scheme is, Semen Lepidii (Semen Descurainiae) 4-9; Dalbergia wood 5-10; Root tuber of aromatic turmeric 3-8; Lily 6-11; Almond 8-12; Grape wine 340-520.
What be more preferably is, Semen Lepidii (Semen Descurainiae) 4-9; Dalbergia wood 5-10; Root tuber of aromatic turmeric 3-8; Lily 6-11; Almond 8-12; Grape wine 340-520.
Described a kind of preparation of wine with fat-reducing effect, step is as follows:
(1) get Semen Lepidii (Semen Descurainiae) and almond removing crust, spray salt solution, infiltrate 5-10 minute (preferred: to infiltrate 7.5 minutes), be placed in hot pot and stir-fry to yellow, taking-up cools, and pulverizes and sieves, and loads in dialysis tubing;
(2) dalbergia wood, root tuber of aromatic turmeric and lily are cleaned removal of impurities, put into marmite, soak 10 minutes, intense fire is heated to boiling, then adds step (1) gained dialysis tubing, turns little fire and decocts, close fire and filter, collect filtrate;
(3) by step (2) the remaining dregs of a decoction, add water and continue to decoct 20-30 minute (preferably: continue to decoct 22-28 minute; Be more preferably: continue decoction 25 minutes), mix with step (2) gained filtrate after filtering, be evaporated to 1/3 of original volume;
(4) grape removed carpopodium, clean, drain, pinch brokenly with hand, load in vial, account for 2/3 of vial cumulative volume, add rock sugar and the mixing of step (3) gained concentrated solution, fermentation is preserved in sealing, uncaps every day and ventilates and stir 3 minutes;
(5) by step (4) made fermented liquid sterile gauze press filtration, under being placed in 20 DEG C of conditions, strict seal, carries out Secondary Fermentation, removes precipitation, filter to obtain clear liquor after fermentation ends, and load in Glass Containers, sealing is kept in Dark Place, and obtains grape wine.
Described a kind of preparation of wine with fat-reducing effect, it is (preferred: to pulverize 100-120 mesh sieve that step (1) pulverized 80-140 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
Described a kind of preparation of wine with fat-reducing effect, the 5-7 that step (2) amount of water is boiled raw materials quality is doubly (preferred: the 5.5-6.5 that amount of water is boiled raw materials quality is doubly; Be more preferably: 6 times that amount of water is boiled raw materials quality).
Described a kind of preparation of wine with fat-reducing effect, step (2) turns little fire and decocts 24-42 minute (preferably: turn little fire and decoct 30-36 minute; Be more preferably: turn little fire and decoct 33 minutes).
Described a kind of preparation of wine with fat-reducing effect, the amount of step (4) rock sugar is the 0.2-0.3 of grape quality doubly (preferred: the amount of rock sugar is 0.25 times of grape quality).
Described a kind of preparation of wine with fat-reducing effect, fermentation time is preserved in step (4) sealing, and to be 8-16 days (preferred: it is 10-14 days that fermentation time is preserved in sealing; Be more preferably: it is 12 days that fermentation time is preserved in sealing).
Described a kind of preparation of wine with fat-reducing effect, it is (preferred: the Secondary Fermentation time is 28-32 days that step (5) the Secondary Fermentation time is 24-36 days; Be more preferably: the Secondary Fermentation time is 30 days).
A kind of grape wine scientific formulation with fat-reducing effect provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, the present invention fill a prescription Clinical Practice sum up form, be applicable to the crowd of Different age group;
2, products obtained therefrom of the present invention has effect of promoting flow of QI and blood, Yin nourishing and lung moistening, Be very effective;
3, the present invention's Chinese medicinal materials used, safety has no side effect, the adjustable physical function of long-term taking.
Embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1there is a grape wine for fat-reducing effect, be prepared from (every part of 50g) primarily of following bulk drugs: Semen Lepidii (Semen Descurainiae) 4 parts, dalbergia wood 5 parts, root tuber of aromatic turmeric 3 parts, lily 6 parts, 8 parts, almond, grape wine 340 parts.Above-mentioned a kind of preparation of wine with fat-reducing effect is:
(1) get Semen Lepidii (Semen Descurainiae) and almond removing crust, spray salt solution, infiltrate 5 minutes, be placed in hot pot and stir-fry to yellow, taking-up cools, and pulverizes 80 mesh sieves, loads in dialysis tubing;
(2) dalbergia wood, root tuber of aromatic turmeric and lily are cleaned removal of impurities, put into marmite, add the water soaking 10 minutes of boiled raw materials quality 5 times, intense fire is heated to boiling, then adds step (1) gained dialysis tubing, turns little fire and decocts 24 minutes, close fire and filter, collect filtrate;
(3) by step (2) the remaining dregs of a decoction, add water and continue decoction 20 minutes, mix with step (2) gained filtrate after filtering, be evaporated to 1/3 of original volume;
(4) kyoto grape removed carpopodium, clean, drain, pinch brokenly with hand, load in vial, account for 2/3 of vial cumulative volume, add rock sugar and the mixing of step (3) gained concentrated solution of grape quality 0.2 times, fermentation 8 days is preserved in sealing, uncaps every day and ventilates and stir 3 minutes;
(5), by step (4) made fermented liquid sterile gauze press filtration, under being placed in 20 DEG C of conditions, strict seal, carries out Secondary Fermentation, time is 24 days, removes precipitation, filter to obtain clear liquor after fermentation ends, load in Glass Containers, sealing is kept in Dark Place, and obtains grape wine.
embodiment 2there is a grape wine for fat-reducing effect, be prepared from (every part of 50g) primarily of following bulk drugs: Semen Lepidii (Semen Descurainiae) 9 parts, dalbergia wood 10 parts, root tuber of aromatic turmeric 8 parts, lily 11 parts, 12 parts, almond, grape wine 520 parts.Above-mentioned a kind of preparation of wine with fat-reducing effect is:
(1) get Semen Lepidii (Semen Descurainiae) and almond removing crust, spray salt solution, infiltrate 10 minutes, be placed in hot pot and stir-fry to yellow, taking-up cools, and pulverizes 140 mesh sieves, loads in dialysis tubing;
(2) dalbergia wood, root tuber of aromatic turmeric and lily are cleaned removal of impurities, put into marmite, add the water soaking 10 minutes of boiled raw materials quality 7 times, intense fire is heated to boiling, then adds step (1) gained dialysis tubing, turns little fire and decocts 42 minutes, close fire and filter, collect filtrate;
(3) by step (2) the remaining dregs of a decoction, add water and continue decoction 30 minutes, mix with step (2) gained filtrate after filtering, be evaporated to 1/3 of original volume;
(4) Vitis Amurensis removed carpopodium, clean, drain, pinch brokenly with hand, load in vial, account for 2/3 of vial cumulative volume, add rock sugar and the mixing of step (3) gained concentrated solution of grape quality 0.3 times, fermentation 16 days is preserved in sealing, uncaps every day and ventilates and stir 3 minutes;
(5), by step (4) made fermented liquid sterile gauze press filtration, under being placed in 20 DEG C of conditions, strict seal, carries out Secondary Fermentation, time is 36 days, removes precipitation, filter to obtain clear liquor after fermentation ends, load in Glass Containers, sealing is kept in Dark Place, and obtains grape wine.
Typical case: xxx, women, 35 years old.Patient likes eating greasy food, and infrequently moves, and causes obese, and health check-up is found suffers from hyperlipidemia and hypertension symptom, and once took the medicines such as Xuezhikang, rate and blood-lipid decreased is not obvious, because of without other uncomfortable diseases, does not just think that Long-term taking medicine is treated.
Introduce through friend and take a kind of grape wine with fat-reducing effect of this example gained, each 40-80ml, one day twice, after patient takes one month, the mental status is clearly better, sufficient sleeping, after adhering to taking three months, return examination in hospital, rate and blood-lipid decreased is to normal range, and hyperglycemic symptoms is also significantly alleviated.
embodiment 3there is a grape wine for fat-reducing effect, be prepared from (every part of 50g) primarily of following bulk drugs: Semen Lepidii (Semen Descurainiae) 5 parts, dalbergia wood 6 parts, root tuber of aromatic turmeric 4 parts, lily 7 parts, 9 parts, almond, grape wine 390 parts.Above-mentioned a kind of preparation of wine with fat-reducing effect is:
(1) get Semen Lepidii (Semen Descurainiae) and almond removing crust, spray salt solution, infiltrate 5 minutes, be placed in hot pot and stir-fry to yellow, taking-up cools, and pulverizes 100 mesh sieves, loads in dialysis tubing;
(2) dalbergia wood, root tuber of aromatic turmeric and lily are cleaned removal of impurities, put into marmite, add the water soaking 10 minutes of boiled raw materials quality 5.5 times, intense fire is heated to boiling, then adds step (1) gained dialysis tubing, turns little fire and decocts 30 minutes, close fire and filter, collect filtrate;
(3) by step (2) the remaining dregs of a decoction, add water and continue decoction 22 minutes, mix with step (2) gained filtrate after filtering, be evaporated to 1/3 of original volume;
(4) kyoto grape removed carpopodium, clean, drain, pinch brokenly with hand, load in vial, account for 2/3 of vial cumulative volume, add rock sugar and the mixing of step (3) gained concentrated solution of grape quality 0.2 times, fermentation 10 days is preserved in sealing, uncaps every day and ventilates and stir 3 minutes;
(5), by step (4) made fermented liquid sterile gauze press filtration, under being placed in 20 DEG C of conditions, strict seal, carries out Secondary Fermentation, time is 28 days, removes precipitation, filter to obtain clear liquor after fermentation ends, load in Glass Containers, sealing is kept in Dark Place, and obtains grape wine.
embodiment 4there is a grape wine for fat-reducing effect, be prepared from (every part of 50g) primarily of following bulk drugs: Semen Lepidii (Semen Descurainiae) 8 parts, dalbergia wood 9 parts, root tuber of aromatic turmeric 7 parts, lily 10 parts, 11 parts, almond, grape wine 470 parts.Above-mentioned a kind of preparation of wine with fat-reducing effect is:
(1) get Semen Lepidii (Semen Descurainiae) and almond removing crust, spray salt solution, infiltrate 10 minutes, be placed in hot pot and stir-fry to yellow, taking-up cools, and pulverizes 120 mesh sieves, loads in dialysis tubing;
(2) dalbergia wood, root tuber of aromatic turmeric and lily are cleaned removal of impurities, put into marmite, add the water soaking 10 minutes of boiled raw materials quality 6.5 times, intense fire is heated to boiling, then adds step (1) gained dialysis tubing, turns little fire and decocts 36 minutes, close fire and filter, collect filtrate;
(3) by step (2) the remaining dregs of a decoction, add water and continue decoction 28 minutes, mix with step (2) gained filtrate after filtering, be evaporated to 1/3 of original volume;
(4) Vitis Amurensis removed carpopodium, clean, drain, pinch brokenly with hand, load in vial, account for 2/3 of vial cumulative volume, add rock sugar and the mixing of step (3) gained concentrated solution of grape quality 0.3 times, fermentation 14 days is preserved in sealing, uncaps every day and ventilates and stir 3 minutes;
(5), by step (4) made fermented liquid sterile gauze press filtration, under being placed in 20 DEG C of conditions, strict seal, carries out Secondary Fermentation, time is 32 days, removes precipitation, filter to obtain clear liquor after fermentation ends, load in Glass Containers, sealing is kept in Dark Place, and obtains grape wine.
Typical case: xxx, women, 48 years old.Main suit: to have a dizzy spell, chest distress and palpitation symptoms half a year; Medical history: occurred having a dizzy spell without obvious inducement before patient half a year, the symptom such as chest distress and palpitation symptoms, just pant under activity, spiritlessness and weakness a little, to examination in hospital, is diagnosed as hyperlipidemia.
Untoward reaction is produced because taking Western medicine, just the methods for the treatment of asked about everywhere, through recommending to take a kind of grape wine with fat-reducing effect of this example gained, each 40-80ml, one day twice, after patient takes two weeks, uncomfortable disease alleviates to some extent, continues to take two months, spirit and muscle power significantly promote, uncomfortable disease basically eliminate, consolidate again a course for the treatment of, rate and blood-lipid decreased is to normal range.
embodiment 5there is a grape wine for fat-reducing effect, be prepared from (every part of 50g) primarily of following bulk drugs: Semen Lepidii (Semen Descurainiae) 6.5 parts, dalbergia wood 7.5 parts, root tuber of aromatic turmeric 5.5 parts, lily 8.5 parts, 10 parts, almond, grape wine 430 parts.Above-mentioned a kind of preparation of wine with fat-reducing effect is:
(1) get Semen Lepidii (Semen Descurainiae) and almond removing crust, spray salt solution, infiltrate 7.5 minutes, be placed in hot pot and stir-fry to yellow, taking-up cools, and pulverizes 110 mesh sieves, loads in dialysis tubing;
(2) dalbergia wood, root tuber of aromatic turmeric and lily are cleaned removal of impurities, put into marmite, add the water soaking 10 minutes of boiled raw materials quality 6 times, intense fire is heated to boiling, then adds step (1) gained dialysis tubing, turns little fire and decocts 33 minutes, close fire and filter, collect filtrate;
(3) by step (2) the remaining dregs of a decoction, add water and continue decoction 25 minutes, mix with step (2) gained filtrate after filtering, be evaporated to 1/3 of original volume;
(4) kyoto grape removed carpopodium, clean, drain, pinch brokenly with hand, load in vial, account for 2/3 of vial cumulative volume, add rock sugar and the mixing of step (3) gained concentrated solution of grape quality 0.25 times, fermentation 12 days is preserved in sealing, uncaps every day and ventilates and stir 3 minutes;
(5) by step (4) made fermented liquid sterile gauze press filtration, under being placed in 20 DEG C of conditions, strict seal, carries out Secondary Fermentation 30 days, removes precipitation, filter to obtain clear liquor after fermentation ends, and load in Glass Containers, sealing is kept in Dark Place, and obtains grape wine.
The pharmacology of the present invention's main Chinese medicine material used is as follows:
Semen Lepidii (Semen Descurainiae): base is former: be the seed of cress Lepidium apetalum, North America semolina or descurainia sophia (l.) webb ex prantl.Chemical Composition: the fatty oil of Lepidium apetalum seed, sinigrin, protein, carbohydrate.Nature and flavor: arduous, cold.Gui Jing: enter lung, urinary bladder channel.Function cures mainly: the capable water of lower gas.Control lung heap soil or fertilizer over and around the roots and breathe heavily urgency, phlegm bank is coughed, oedema turgor.
Dalbergia wood: property is pungent, temperature.Return liver, the spleen channel.There is promoting flow of QI and blood, pain relieving, hemostasia effect.Be generally used for epigastric pain, hypochondriac pain due to stagnation of liverQI, obstruction of qi in the chest shouting pain, injury from falling down, traumatic hemorrhage.
Root tuber of aromatic turmeric: base is former: be the block root of zingiberaceous plant turmeric, root tuber of aromatic turmeric or curcuma zedoary.Property pungent, bitter, cold.Return liver, the heart, lung channel.Can regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Be generally used for through closing dysmenorrhoea, chest and abdomen swelling and pain, shouting pain, pyreticosis coma, epilepsy is gone mad, and jaundice urine is red.
Lily: base is former: be liliaceous plant lily, Lilium tenuifolium, white trumpet lily and the scale leaf belonging to various plants bulb together thereof.Nature and flavor with return through: sweet, cold.The thoughts of returning home, lung channel.There is Yin nourishing and lung moistening, effect of clearing away the heart fire and tranquillizing.For deficiency of Yin cough caused by dryness, labor is coughed hemoptysis, and dysphoria is palpitated with fear, and insomnia and dreamful sleep is absent-minded.
Almond: base is former: be the dry seed of the bitters such as rosaceous plant apricot or ansu apricot.Composition: containing Vitamin B17 about 3%, fatty oil (Prunus amygdalus oil) about 50%, protein and various total free aminoacids.Nature and flavor: bitter, temperature, poisonous.Enter lung, large intestine channel.There is expelling phlegm for arresting cough, relieving asthma, effect of ease constipation.For controlling exogenous cough, breathe heavily full, larynx numbness, the dry constipation of intestines.Concoct: almond: pick clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean.
Grape (selecting kyoto grape or Vitis Amurensis): nature and flavor: sweet acid is flat.Gui Jing: enter lung, spleen, kidney channel.Function cures mainly: fill blood, strengthening the bones and muscles, diuresis.Control deficient qi and blood, cough due to deficiency of the lung, palpitation and night sweat, Bi condition, gonorrhoea, edema.
test example 1a kind of clinical application with the grape wine (embodiment 5) of fat-reducing effect of gained of the present invention:
Choose crowd: in December ,-2014 in January, 2014, according to medical case history, patient 372 example of hyperlipidemia is suffered from five hospital's screenings, wherein the male sex 194 example, women 178 example, the range of age 20-64 year, 38.9 ± 2.4 years old mean age, Case definition is: general with grownup's Diagnostic Value of Fasting Serum total cholesterol more than 572 mM/ls, triglyceride level, more than 1.70 mM/ls, is diagnosed as hyperlipidaemia.5.2 ~ 5.7 mM/ls of persons, total cholesterol is called that marginality raises.。
Before test, patient is divided into two groups at random, experimental group 232 example and control group 140 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes a kind of grape wine with fat-reducing effect of gained of the present invention, one day twice, each 40-80ml; Control group takes other conventional medicines (zhibituo, Simvastatin, FENOBRATE top grade).Take four months continuously, treatments period is observed two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptom is all eliminated, and lipids contents drops to normal range; (2) effective: clinical symptom basically eliminate, lipids contents is close to normal range; (3) invalid: before and after treatment, symptom and sign are without change.
Clinical effectiveness: the treatment result of two groups is as shown in table 1:
As shown in Table 1, the total effective rate of experimental group is 97.0%, and the total effective rate of control group is 80.7%, significantly lower than the result for the treatment of of experimental group, illustrates that gained grape wine of the present invention effectively can reduce blood fat, evident in efficacy.
Before and after treatment, the uncomfortable disease number of cases of two groups is as shown in table 2:
As shown in Table 2, take gained of the present invention experimental group result for the treatment of vinous remarkable, uncomfortable disease is improved obviously, and curative effect is obviously better than the control group patient using conventional medicine.
Gained grape wine of the present invention, select the Semen Lepidii (Semen Descurainiae) of the capable water of lower gas, the dalbergia wood of promoting blood circulation and stopping pain, the root tuber of aromatic turmeric of regulating qi to disperse stagnation, the lily of clearing away the heart fire and tranquillizing, the almond of ease constipation of relievining asthma, then with the health-care effect of grape wine itself, plurality of raw materials acts synergistically, and all has significant curative effect for the uncomfortable disease caused by hyperlipidemia.
It should be pointed out that embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. there is a grape wine for fat-reducing effect, it is characterized in that, be prepared from primarily of following raw materials according, be mass parts: Semen Lepidii (Semen Descurainiae) 4-9; Dalbergia wood 5-10; Root tuber of aromatic turmeric 3-8; Lily 6-11; Almond 8-12; Grape 340-520.
2. a kind of grape wine with fat-reducing effect as claimed in claim 1, is characterized in that, Semen Lepidii (Semen Descurainiae) 5-8; Dalbergia wood 6-9; Root tuber of aromatic turmeric 4-7; Lily 7-10; Almond 9-11; Grape 390-470.
3. a kind of grape wine with fat-reducing effect as claimed in claim 1, is characterized in that, Semen Lepidii (Semen Descurainiae) 6.5; Dalbergia wood 7.5; Root tuber of aromatic turmeric 5.5; Lily 8.5; Almond 10; Grape 430.
4. a kind of preparation of wine with fat-reducing effect as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) get Semen Lepidii (Semen Descurainiae) and almond removing crust, spray salt solution, infiltrate 5-10 minute (preferred: to infiltrate 7.5 minutes), be placed in hot pot and stir-fry to yellow, taking-up cools, and pulverizes and sieves, and loads in dialysis tubing;
(2) dalbergia wood, root tuber of aromatic turmeric and lily are cleaned removal of impurities, put into marmite, soak 10 minutes, intense fire is heated to boiling, then adds step (1) gained dialysis tubing, turns little fire and decocts, close fire and filter, collect filtrate;
(3) by step (2) the remaining dregs of a decoction, add water and continue to decoct 20-30 minute (preferably: continue to decoct 22-28 minute; Be more preferably: continue decoction 25 minutes), mix with step (2) gained filtrate after filtering, be evaporated to 1/3 of original volume;
(4) grape removed carpopodium, clean, drain, pinch brokenly with hand, load in vial, account for 2/3 of vial cumulative volume, add rock sugar and the mixing of step (3) gained concentrated solution, fermentation is preserved in sealing, uncaps every day and ventilates and stir 3 minutes;
(5) by step (4) made fermented liquid sterile gauze press filtration, under being placed in 20 DEG C of conditions, strict seal, carries out Secondary Fermentation, removes precipitation, filter to obtain clear liquor after fermentation ends, and load in Glass Containers, sealing is kept in Dark Place, and obtains grape wine.
5. a kind of preparation of wine with fat-reducing effect as claimed in claim 4, is characterized in that, it is (preferred: to pulverize 100-120 mesh sieve that step (1) pulverized 80-140 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
6. a kind of preparation of wine with fat-reducing effect as claimed in claim 4, is characterized in that, the 5-7 that step (2) amount of water is boiled raw materials quality is doubly (preferred: the 5.5-6.5 that amount of water is boiled raw materials quality doubly; Be more preferably: 6 times that amount of water is boiled raw materials quality).
7. a kind of preparation of wine with fat-reducing effect as claimed in claim 4, is characterized in that, step (2) turn little fire decoct 24-42 minute (preferred: to turn little fire and decoct 30-36 minute; Be more preferably: turn little fire and decoct 33 minutes).
8. a kind of preparation of wine with fat-reducing effect as claimed in claim 4, is characterized in that, the amount of step (4) rock sugar is the 0.2-0.3 of grape quality doubly (preferred: the amount of rock sugar is 0.25 times of grape quality).
9. a kind of preparation of wine with fat-reducing effect as claimed in claim 4, is characterized in that, step (4) sealing preserve fermentation time be 8-16 days (preferred: it is 10-14 days that fermentation time is preserved in sealing; Be more preferably: it is 12 days that fermentation time is preserved in sealing).
10. a kind of preparation of wine with fat-reducing effect as claimed in claim 4, is characterized in that, step (5) the Secondary Fermentation time be 24-36 days (preferred: the Secondary Fermentation time is 28-32 days; Be more preferably: the Secondary Fermentation time is 30 days).
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CN201610201853.0A CN105695204A (en) 2015-03-23 2015-03-23 Preparation method of wine with lipid reducing function
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CN106492119A (en) * 2016-12-02 2017-03-15 四川天联药业有限公司 Blood fat reducing granules containing seed of pepper weed or flixweed tansymustard

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KR101223682B1 (en) * 2010-09-30 2013-01-22 이상수 Method for producing functional cosmetic composition and the cosmetic
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CN106047547A (en) * 2016-05-27 2016-10-26 马艳敏 Red koji wine and preparation method thereof
CN106492119A (en) * 2016-12-02 2017-03-15 四川天联药业有限公司 Blood fat reducing granules containing seed of pepper weed or flixweed tansymustard

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