CN104689078A - Blood activating external application ointment for promoting injured bone healing and preparation method thereof - Google Patents

Blood activating external application ointment for promoting injured bone healing and preparation method thereof Download PDF

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CN104689078A
CN104689078A CN201510141519.6A CN201510141519A CN104689078A CN 104689078 A CN104689078 A CN 104689078A CN 201510141519 A CN201510141519 A CN 201510141519A CN 104689078 A CN104689078 A CN 104689078A
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rhizoma
herba
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吴洪霞
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Abstract

The invention discloses a blood activating external application ointment for promoting injured bone healing. The blood activating external application ointment is prepared from, by weight, 5-15 parts of ligusticum wallichii, 8-17 parts of bletilla striata, 6-12 parts of cimicifugae foetidae, 5-15 parts of cortex periplocae, 6-10 parts of panax notoginseng, 5-15 parts of dandelions,10-14 parts of coptis chinensis, 7-13 parts of radix clematidis, 8-14 parts of lycopodium clavatum, 3-9 parts of monkshood, 4-11 parts of fructus cnidii, 9-16 parts of solidago virgaurea, 3-8 parts of garden balsam stems, 8-15 parts of rhizoma dioscoreae nipponicae, 2-4 parts of woodlice, 6-8 parts of dysosma versipellis, 5-7 parts of gerbera and 15-18 parts of honeysuckle. The tendon relaxing and blood activating pill is based on the principle of promoting injured bone healing in traditional Chinese medics and Chinese medicines. The selected traditional Chinese medicine materials have the functions of relaxing tendons, activating blood, removing blood stases, and activating meridians to stop pain, the blood activating external application ointment is low in manufacturing cost, will not cause economical burdens on patients when used for a long time and therefore is ideal medicine for promoting injured bone healing.

Description

A kind of external application ointment machin its preparation method of invigorating blood circulation promoting the injury of the bone to heal
Technical field
The invention discloses one to invigorate blood circulation external application ointment, especially promote the external application ointment machin its preparation method of invigorating blood circulation of injury of the bone healing.Belong to traditional Chinese medicine field.
Background technology
In Traditional Chinese Medicine, bone injury is a more wide in range concept, comprises fracture, joint dislocation, the injury of tendon and muscle, bone injury, bone
The diseases such as membrane damage, also comprise the diseases such as hyperosteogeny, scapulohumeral periarthritis, cervical spondylosis, prolapse of lumbar intervertebral disc, rheumatic arthritis, to these diseases, the Therapeutic Method of doctor trained in Western medicine is generally oral drugs or is aided with physical therapy, massage etc., its effect also just controls symptom development, and be difficult to radical cure, and oral western medicine also has certain toxic and side effects.
In the method for existing promotion bone injury healing, Authorization Notice No. CN 101933999 B(application number 200910065367.0) the medicine that patent discloses a kind of set a broken bone, it is characterized in that being prepared from by the raw material of following weight parts: Radix Codonopsis 10-15, Poria 10-15, Fructus Lycii 10-15, Rhizoma Atractylodis Macrocephalae 8-12, Radix Salviae Miltiorrhizae 15-20, Fructus Chaenomelis 8-12, Radix Achyranthis Bidentatae 10-15, Radix Angelicae Sinensis 8-12, Cortex Periplocae 5-10.Authorization Notice No. CN 102526328 B(application number 201210039216.X) the medicine that patent discloses a kind of set a broken bone, it is characterized in that, each raw material is by following weight proportion composition: major ingredient: Radix Angelicae Sinensis 5-10 part, Radix Salviae Miltiorrhizae 10-15 part, Radix Linderae 10-15 part, Caulis Lonicerae 15-30 part, Radix Rehmanniae Preparata 12-15 part, Rhizoma Polygoni Cuspidati 5-10 part, Ramulus Mori 8-10 part, Ramulus Sambuci Williamsii 6-10 part, Folium Artemisiae Argyi 15-20 part, soil Fructus Cnidii 11-15 part, Cortex Eucommiae 5-10 part, Radix Dipsaci 5-10 part, Semen Strychni 5-8 part, Ramulus Cinnamomi 9-13 part, Rhizoma Et Radix Notopterygii 10-15 part, Rhizoma Atractylodis 5-10 part, Folium Artemisiae Argyi 15-20 part, Radix Clematidis 15-20 part, Caulis Spatholobi 8-10 part, Cortex Periplocae 10-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 7-10 part, Scorpio 10-15 part, Radix Angelicae Dahuricae 5-10 part, Radix Paeoniae Rubra 8-10 part, Cornu Cervi Pantotrichum 4-8 part, Moschus 3-5 part
Chinese medicine occupies very consequence in promotion bone injury healing as can be seen here, but its main dosage form of existing patent is decoction, for promoting the effect of bone injury healing and not as compositions ideal, can causing extra burden to the health of patient.
Summary of the invention
For the present situation of existing promotion injury of the bone healing curative effect deficiency, an object of the present invention is to provide a kind of external application ointment of invigorating blood circulation promoting the injury of the bone to heal, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The external application ointment of invigorating blood circulation promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from: Rhizoma Chuanxiong 5-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 8-17 part, Rhizoma Cimicifugae 6-12 part, Cortex Periplocae 5-15 part, Radix Notoginseng 6-10 part, Herba Taraxaci 5-15 part, Rhizoma Coptidis 10-14 part, Radix Clematidis 7-13 part, Herba Lycopodii 8-14 part, Radix Aconiti Lateralis Preparata 3-9 part, Fructus Cnidii 4-11 part, Herba Solidaginis 9-16 part, Herba speranskiae tuberculatae 3-8 part, Rhizoma Dioscoreae Nipponicae 8-15 part, Eupolyphaga Seu Steleophaga 2-4 part, Radix et Rhizoma Dysosmatis 6-8 part, Herba Leibnitziae 5-7 part, Flos Lonicerae 15-18 part.
A kind of external application ointment of invigorating blood circulation promoting the injury of the bone to heal, the scheme be more preferably, takes off the primary raw material stating weight proportion and is prepared from: Rhizoma Chuanxiong 8-13 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 12-14 part, Rhizoma Cimicifugae 8-10 part, Cortex Periplocae 8-13 part, Radix Notoginseng 7-9 part, Herba Taraxaci 8-13 part, Rhizoma Coptidis 11-13 part, Radix Clematidis 9-11 part, Herba Lycopodii 10-12 part, Radix Aconiti Lateralis Preparata 5-7 part, Fructus Cnidii 6-9 part, Herba Solidaginis 11-15 part, Herba speranskiae tuberculatae 4-7 part, Rhizoma Dioscoreae Nipponicae 10-13 part, Eupolyphaga Seu Steleophaga 2.5-3.5 part, Radix et Rhizoma Dysosmatis 6.5-7.5 part, Herba Leibnitziae 5.5-6.5 part, Flos Lonicerae 16-17 part.
The external application ointment of invigorating blood circulation promoting the injury of the bone to heal, best scheme, takes off the primary raw material stating weight proportion and is prepared from: Rhizoma Chuanxiong 11 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 13 parts, Rhizoma Cimicifugae 9 parts, Cortex Periplocae 12 parts, Radix Notoginseng 8 parts, Herba Taraxaci 11.5 parts, Rhizoma Coptidis 12 parts, Radix Clematidis 10 parts, Herba Lycopodii 11 parts, Radix Aconiti Lateralis Preparata 6 parts, Fructus Cnidii 7.5 parts, Herba Solidaginis 13 parts, Herba speranskiae tuberculatae 5 parts, Rhizoma Dioscoreae Nipponicae 11.5 parts, Eupolyphaga Seu Steleophaga 3 parts, Radix et Rhizoma Dysosmatis 7 parts, Herba Leibnitziae 6 parts, Flos Lonicerae 16.5 parts.
The preparation process of above-mentioned external application ointment of invigorating blood circulation is as follows:
1. get Eupolyphaga Seu Steleophaga to clean, drain away the water, get Eupolyphaga Seu Steleophaga weight 1-3 edible oil doubly, put into the hot pot dryouied, drop into Eupolyphaga Seu Steleophaga, frying 3-7 minute when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;
2. Rhizoma Chuanxiong, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 80-120 mesh sieve stand-by;
3. Rhizoma Cimicifugae, Cortex Periplocae, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, and slightly stewing 5-15 hour, takes out and drain yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;
4. Radix Clematidis, Herba Lycopodii, Radix Aconiti Lateralis Preparata, Fructus Cnidii, Herba Solidaginis, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 20-40 minute, cover lid, at decoction 5-15 minute, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 4-8 days in the sunlight, dries 10-20 minute slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;
5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Add Cera Flava after thick paste being heated to 30-40 DEG C, after Cera Flava dissolves completely, bottle and obtain ointment.
The preparation method of above-mentioned external application ointment of invigorating blood circulation, 1. step gets Eupolyphaga Seu Steleophaga weight 1.5-2.5 edible oil doubly (preferred, to get the edible oil of Eupolyphaga Seu Steleophaga weight 2 times).
The preparation method of above-mentioned external application ointment of invigorating blood circulation, step 2. fine powder crosses 90-110 mesh sieve (preferred, fine powder, crosses 100 mesh sieves).
The preparation method of above-mentioned external application ointment of invigorating blood circulation, step is slightly stewing 8-13 hour 3., takes out and drains yellow wine (preferred, slightly stewing 10 hours, to take out and drain yellow wine).
The preparation method of above-mentioned external application ointment of invigorating blood circulation, 4. step decocts with water to boiling, turns slow fire boiling 25-35 minute (preferred, to decoct with water to boiling, turn slow fire boiling 30 minutes).
The preparation method of above-mentioned external application ointment of invigorating blood circulation, step 4. filtering residue is exposed to the sun 5-7 days in the sunlight, dries slowly 13-18 minute (preferred, filtering residue is exposed to the sun 6 days in the sunlight, be placed in little fire on iron plate dry 15 minutes slowly) being placed in little fire on iron plate.
The preparation method of above-mentioned external application ointment of invigorating blood circulation, step adds Cera Flava (preferred, to add Cera Flava after thick paste being heated to 35 DEG C) after 5. thick paste being heated to 33-38 DEG C.
Using method: for making the present invention's external application ointment of invigorating blood circulation reach optimum therapeuticing effect, every day twice, half an hour after meal sooner or later, getting 5-10g, take after mixing it with hot water, 10 days is a course for the treatment of.
This external application ointment of invigorating blood circulation, to chronic bronchitis Be very effective, not only has effect of relaxing muscles and tendons to promote blood circulation, can also promote that the injury of the bone heals, and causes lethargy for prolonged illness, and look tired person has good medical treatment effect.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Rhizoma Chuanxiong: blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
The Pseudobulbus Bletillae (Rhizoma Bletillae): function cures mainly: astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.Meridian distribution of property and flavor: bitter in the mouth, sweet, puckery, cold in nature, returns lung, liver, stomach warp.There is astringing to arrest bleeding, the merit of detumescence and promoting granulation, for all cards of interior external haemorrhage and carbuncle, scald, rhagadia manus et pedis, anal fissure etc.
Rhizoma Cimicifugae: return lung, spleen, large intestine, stomach warp.Seasonal epidemic pathogens epidemic disease, headache cold and heat, laryngalgia, aphtha, macule is not saturating; Sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women is collapsed, band, and uterus drops; Carbuncle sore tumefacting virus.
Cortex Periplocae: acrid in the mouth, hardship, warm in nature.Return through liver, kidney, heart channel.Function has inducing diuresis to remove edema, wind-damp dispelling, effect of bone and muscle strengthening.Cure mainly and be used for the treatment of edema of lower limbs, shortness of breath and palpitation, anemofrigid-damp arthralgia, soreness of the waist and knees.
Radix Notoginseng: sweet, the micro-hardship of nature and flavor, temperature.Gui Jing returns liver, stomach warp.Effect dissipating blood stasis stops blooding, subduing swelling and relieving pain.Cure mainly for spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Herba Taraxaci: containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in Herba Taraxaci plant.Nature and flavor are sweet, micro-hardship, cold.Return liver, stomach warp.There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Control pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc.Herba Taraxaci is raw-eaten, stir-fry and eat, cook soup, is the plant of dietotherapeutic.
Rhizoma Coptidis: nature and flavor bitter in the mouth, cold in nature.Return through GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect heat clearing and damp drying, eliminating fire and detoxication.Cure mainly damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, and carbuncle treats skin ulcer; External treatment eczema, eczema, auditory meatus is suppurated.
Radix Clematidis: have wind-damp dispelling, the effect of the meridian dredging.Cure mainly: for rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness.
Herba Lycopodii: return through liver,spleen,kidney warp.Effect has expelling wind and removing dampness, effect of relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly for joint aches, joint stuffiness.
Radix Aconiti Lateralis Preparata: acrid in the mouth, sweet, extremely hot in nature.Return through GUIXIN, kidney, spleen channel.Effect recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispersing cold for relieving pain.Cure mainly for YANG-depletion collapse, cold extremities faint pulse, deficiency of heart-YANG, obstruction of qi in the chest and cardialgia, deficiency and coldness is vomited and diarrhoea, coldness and pain in the epigastrium, kidney yang deficiency, sexual impotence cold womb, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Fructus Cnidii: there is dampness and dispel the wind, killing parasites for relieving itching, effect of warming the kidney to invigorate YANG.Be usually used in pudendal pruritus leukorrhagia, eczema pruritus, arthralgia chiefly caused by damp pathogen lumbago, impotence due to deficiency of the kidney, cold womb is infertile.
Herba Solidaginis: base is former: be herb or the root of Compositae Herba Solidaginis platymiscium Herba Solidaginis.Composition: aerial parts is containing saponin component: Herba Solidaginis glycosides, activities of Solidago virgaurea L saponin 3 that is 3, Solidago saponin, solidago canadesis saponin, huge Herba Solidaginis saponin, the triterpene glycosides etc. of Polygalacic acid.The property of medicine: pungent, bitter, cool.Function cures mainly: wind and heat dispersing, removing toxic substances and promoting subsidence of swelling.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, cough due to lung-heat, jaundice, pyretic stranguria, carbuncle furuncle, venom, traumatic injury.
Herba speranskiae tuberculatae: expelling wind and removing dampness, the pungent temperature of these product, Xin Nenghang falls apart, and temperature overcomes the coldness wet.Eight Liver Channel, therefore energy expelling wind and removing dampness, as Compendium of Material Medica is said: Herba speranskiae tuberculatae " controls all rheumatalgia contractures of muscles and bones.If " cause limbs pain because of wind-cold damp pathogen invasion and attack limbs meridians, numb, joint stuffiness.Can select these product, expelling wind and cold victory is wet, and pathogenic factor goes, then all disease spontaneous recovery.2. relaxing muscles and tendons and activating QI and blood in the collateral, the pungent loose temperature of these product is led to, and enters Liver Channel, and liver governing tendons. therefore these product have effect of relaxing muscles and tendons and activating QI and blood in the collateral.For the heresy of affection of exogenous wind-cold, lose a surname through gas, disease is seen that limbs muscle arteries and veins shrinks and is taken out urgency, can not relax and turn freely.Can select Herba speranskiae tuberculatae, expelling wind and cold, relaxing muscles and tendons and activating QI and blood in the collateral controls it.As " the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " namely selects these product, control muscles and bones contracture.3. promoting blood circulation and stopping pain, the pungent loose temperature of these product is led to, and enters Liver Channel blood system, therefore can promoting blood circulation and stopping pain.To upper and lower, trusted subordinate's waist knee joint, inside and outside various pain, all can select these product to control it, and get its pungent temperature and be apt to away, the merit of promoting the circulation of QI of invigorating blood circulation, vim and vigour general rule is not bitterly.4. solution poisons rash, the secret red medicine writing paper of spirit " say: " treat pyretic toxicity." " Yang Cheng Empirical formula " select this product, control toxic swelling from the beginning of." the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " then uses these product, controls eczema scrotum, sore swollen toxin.Therefore Herba speranskiae tuberculatae treatment skin ulcer tinea toxic swelling can be thought, eczema scrotum, general many decoction being used as a lotion.Because this medicine washout also has priming to penetrate meridians, blood vessels, and dispel the wind, invigorate blood circulation, the feature of pain relieving.
Rhizoma Dioscoreae Nipponicae: another name Dioscorea nipponica Mak. Ningpo Yam Rhizome, Rhizoma Dioscoreae Nipponicae, Dioscorea nipponica bone, ground joist, Rhizoma Smilacis Bockii, chicken bone, mountain Radix Dichroae, Radix Dichroae, parthenocissus, tip of a whip dish.Flavor efficacy is bitter, flat.Return liver, lung meridian.Function relaxing muscles and tendons to promote blood circulation, timid wind pain relieving, relieving cough and asthma, timid expectorant.Be applicable to lumbago and skelalgia, muscles and bones numbness, traumatic injury, lumbar sprain and QI divergeny, cough pant.
Eupolyphaga Seu Steleophaga: there is removing blood stasis, effect of reunion of fractured tendons and bones.For traumatic injury, the injury of tendon and muscle is fractured, blood stasis amenorrhea, and postpartum stagnation is suffered from abdominal pain, addiction abdominal mass mass in the abdomen.
Radix et Rhizoma Dysosmatis: base is former: be the root and rhizome of Berberidaceae Dysosma plant Radix et Rhizoma Dysosmatis, Dysosma Pleiantha and dysosma veitchii Fu.Composition: 1. Radix et Rhizoma Dysosmatis rhizome is containing lignanoid: podophyllotoxin, picropodophyllin; Flavonoid: diphyllin kaempferol, Quercetin etc.2. Dysosma Pleiantha rhizome is containing lignanoid: podophyllotoxin, dehydropodophyllotoxin, podophyllotoxone etc.3. dysosma veitchii Fu root is containing deoxypodophyllotoxin ,-peltain, podophyllotoxin, kaempferol-3--D-Glucose glycosides, glucose, sucrose and-sitosterol.The property of medicine: bitter, pungent, temperature.Poisonous.Return lung, Liver Channel.Function cures mainly: removing toxic substances of reducing phlegm, eliminating stasis and resolving masses.Cure mainly cough, laryngopharynx swelling and pain, scrofula, goiter, nameless gall, herpes zoster, venom, traumatic injury, rheumatic arthralgia.
Herba Leibnitziae: having another name called and burn golden grass, little fire weed, shank grass, is the herb of Compositae Gerbera plant Herba Leibnitziae.The property of medicine: this product is crispaturaed agglomerating, in withered green, rhizome is short, and lower raw most thin fibrous root, achene spindle, two ends are shunk, feeble QI, and bitter in the mouth is cold in nature.Composition: aerial parts, containing coumarin kind compound, contains Virginia prune glucoside again, nail-like boil glycosides.Find according to modern pharmacological research, this medical instrument has antibacterial, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling effect, for cough due to lung-heat, and damp-heat dysentery, pyretic stranguria, rheumatic arthritis etc.
Flos Lonicerae: its effect mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
The present invention invigorate blood circulation external application ointment based on Chinese medicine promote the injury of the bone healing principle.The medical material selected all has relaxing muscles and tendons to promote blood circulation, promotes effect of injury of the bone healing, carries out determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs in various degree, belong to the prescription for the treatment of both the principal and secondary aspects of a disease for the injury of the bone, has fabulous therapeutical effect to the healing of the promotion injury of the bone.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1: a kind of external application ointment of invigorating blood circulation promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Chuanxiong 5 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8 parts, Rhizoma Cimicifugae 6 parts, Cortex Periplocae 5 parts, Radix Notoginseng 6 parts, Herba Taraxaci 5 parts, Rhizoma Coptidis 10 parts, Radix Clematidis 7 parts, Herba Lycopodii 8 parts, Radix Aconiti Lateralis Preparata 3 parts, Fructus Cnidii 4 parts, Herba Solidaginis 9 parts, Herba speranskiae tuberculatae 3 parts, Rhizoma Dioscoreae Nipponicae 8 parts, Eupolyphaga Seu Steleophaga 2 parts, Radix et Rhizoma Dysosmatis 6 parts, Herba Leibnitziae 5 parts, Flos Lonicerae 15 parts.
The preparation method of the external application ointment of invigorating blood circulation of above-mentioned promotion injury of the bone healing, step is as follows:
1. get Eupolyphaga Seu Steleophaga to clean, drain away the water, get the edible oil of Eupolyphaga Seu Steleophaga weight 1 times, put into the hot pot dryouied, drop into Eupolyphaga Seu Steleophaga, frying 3 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;
2. Rhizoma Chuanxiong, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 80 mesh sieves stand-by;
3. Rhizoma Cimicifugae, Cortex Periplocae, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 5 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;
4. Radix Clematidis, Herba Lycopodii, Radix Aconiti Lateralis Preparata, Fructus Cnidii, Herba Solidaginis, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 20 minutes, cover lid, decoction 5 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 4 days in the sunlight, dries 10-minute slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;
5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Add Cera Flava after thick paste being heated to 30 DEG C, after Cera Flava dissolves completely, bottle and obtain ointment.
embodiment 2: a kind of external application ointment of invigorating blood circulation promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Chuanxiong 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 17 parts, Rhizoma Cimicifugae 12 parts, Cortex Periplocae 15 parts, Radix Notoginseng 10 parts, Herba Taraxaci 15 parts, Rhizoma Coptidis 14 parts, Radix Clematidis 13 parts, Herba Lycopodii 14 parts, Radix Aconiti Lateralis Preparata 9 parts, Fructus Cnidii 11 parts, Herba Solidaginis 16 parts, Herba speranskiae tuberculatae 8 parts, Rhizoma Dioscoreae Nipponicae 15 parts, Eupolyphaga Seu Steleophaga 4 parts, Radix et Rhizoma Dysosmatis 8 parts, Herba Leibnitziae 7 parts, Flos Lonicerae 18 parts.
The preparation method of the external application ointment of invigorating blood circulation of above-mentioned promotion injury of the bone healing, step is as follows:
1. get Eupolyphaga Seu Steleophaga to clean, drain away the water, get the edible oil of Eupolyphaga Seu Steleophaga weight 3 times, put into the hot pot dryouied, drop into Eupolyphaga Seu Steleophaga, frying 7 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;
2. Rhizoma Chuanxiong, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 120 mesh sieves stand-by;
3. Rhizoma Cimicifugae, Cortex Periplocae, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 15 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;
4. Radix Clematidis, Herba Lycopodii, Radix Aconiti Lateralis Preparata, Fructus Cnidii, Herba Solidaginis, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 40 minutes, cover lid, decoction 15 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 8 days in the sunlight, dries 20 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;
5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Add Cera Flava after thick paste being heated to 40 DEG C, after Cera Flava dissolves completely, bottle and obtain ointment.
embodiment: 3the external application ointment of invigorating blood circulation promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Chuanxiong 8 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Rhizoma Cimicifugae 8 parts, Cortex Periplocae 8 parts, Radix Notoginseng 7 parts, Herba Taraxaci 8 parts, Rhizoma Coptidis 11 parts, Radix Clematidis 9 parts, Herba Lycopodii 10 parts, Radix Aconiti Lateralis Preparata 5 parts, Fructus Cnidii 6 parts, Herba Solidaginis 11 parts, Herba speranskiae tuberculatae 4 parts, Rhizoma Dioscoreae Nipponicae 10 parts, Eupolyphaga Seu Steleophaga 2.5 parts, Radix et Rhizoma Dysosmatis 6.5 parts, Herba Leibnitziae 5.5 parts, Flos Lonicerae 16 parts.
The preparation method of the external application ointment of invigorating blood circulation of above-mentioned promotion injury of the bone healing, step is as follows:
1. get Eupolyphaga Seu Steleophaga to clean, drain away the water, get the edible oil of Eupolyphaga Seu Steleophaga weight 1.5 times, put into the hot pot dryouied, drop into Eupolyphaga Seu Steleophaga, frying 4 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;
2. Rhizoma Chuanxiong, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 90 mesh sieves stand-by;
3. Rhizoma Cimicifugae, Cortex Periplocae, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 8 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;
4. Radix Clematidis, Herba Lycopodii, Radix Aconiti Lateralis Preparata, Fructus Cnidii, Herba Solidaginis, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 25 minutes, cover lid, decoction 8 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 5 days in the sunlight, dries 13 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;
5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Add Cera Flava after thick paste being heated to 33 DEG C, after Cera Flava dissolves completely, bottle and obtain ointment.
embodiment 4:the external application ointment of invigorating blood circulation promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Chuanxiong 13 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 14 parts, Rhizoma Cimicifugae 10 parts, Cortex Periplocae 13 parts, Radix Notoginseng 9 parts, Herba Taraxaci 13 parts, Rhizoma Coptidis 13 parts, Radix Clematidis 11 parts, Herba Lycopodii 12 parts, Radix Aconiti Lateralis Preparata 7 parts, Fructus Cnidii 9 parts, Herba Solidaginis 15 parts, Herba speranskiae tuberculatae 7 parts, Rhizoma Dioscoreae Nipponicae 13 parts, Eupolyphaga Seu Steleophaga 3.5 parts, Radix et Rhizoma Dysosmatis 7.5 parts, Herba Leibnitziae 6.5 parts, Flos Lonicerae 17 parts.
The preparation method of the external application ointment of invigorating blood circulation of above-mentioned promotion injury of the bone healing, step is as follows:
1. get Eupolyphaga Seu Steleophaga to clean, drain away the water, get the edible oil of Eupolyphaga Seu Steleophaga weight 2.5 times, put into the hot pot dryouied, drop into Eupolyphaga Seu Steleophaga, frying 6 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;
2. Rhizoma Chuanxiong, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 110 mesh sieves stand-by;
3. Rhizoma Cimicifugae, Cortex Periplocae, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 13 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;
4. Radix Clematidis, Herba Lycopodii, Radix Aconiti Lateralis Preparata, Fructus Cnidii, Herba Solidaginis, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 35 minutes, cover lid, decoction 13 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 7 days in the sunlight, dries 18 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;
5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Add Cera Flava after thick paste being heated to 38 DEG C, after Cera Flava dissolves completely, bottle and obtain ointment.
embodiment 5:the external application ointment of invigorating blood circulation promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Chuanxiong 11 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 13 parts, Rhizoma Cimicifugae 9 parts, Cortex Periplocae 12 parts, Radix Notoginseng 8 parts, Herba Taraxaci 11.5 parts, Rhizoma Coptidis 12 parts, Radix Clematidis 10 parts, Herba Lycopodii 11 parts, Radix Aconiti Lateralis Preparata 6 parts, Fructus Cnidii 7.5 parts, Herba Solidaginis 13 parts, Herba speranskiae tuberculatae 5 parts, Rhizoma Dioscoreae Nipponicae 11.5 parts, Eupolyphaga Seu Steleophaga 3 parts, Radix et Rhizoma Dysosmatis 7 parts, Herba Leibnitziae 6 parts, Flos Lonicerae 16.5 parts.
The preparation method of the external application ointment of invigorating blood circulation of above-mentioned promotion injury of the bone healing, step is as follows:
1. get Eupolyphaga Seu Steleophaga to clean, drain away the water, get the edible oil of Eupolyphaga Seu Steleophaga weight 2 times, put into the hot pot dryouied, drop into Eupolyphaga Seu Steleophaga, frying 5 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;
2. Rhizoma Chuanxiong, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 100 mesh sieves stand-by;
3. Rhizoma Cimicifugae, Cortex Periplocae, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 10 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;
4. Radix Clematidis, Herba Lycopodii, Radix Aconiti Lateralis Preparata, Fructus Cnidii, Herba Solidaginis, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 30 minutes, cover lid, decoction 10 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 6 days in the sunlight, dries 15 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;
5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Add Cera Flava after thick paste being heated to 35 DEG C, after Cera Flava dissolves completely, bottle and obtain ointment.
experimental exampleone: in order to verify the effect of Chinese medicine composition of the present invention (embodiment 5), we have extracted 400 patients and have carried out the experiment of medicine, be divided into experimental group and matched group, experimental group is taken embodiment 5 gained and to be invigorated blood circulation external application ointment, and matched group takes other Chinese medicine promoting injury of the bone healing and Western medicine medicine.Inclusion criteria: through being diagnosed as chronic bronchitis patient, disease 1-10 in age, has chronic bronchitis clinical symptoms one or more.Curative effect situation criterion: 1, cure.After drug administration, malaise symptoms disappears completely; 2, effective.After drug administration, malaise symptoms alleviates or partial disappearance; 3, invalid.After drug administration, malaise symptoms is unchanged.
Table 1: two groups of Clinical efficacy comparison [example] tables 1
Table 1
The present invention's external application ointment cure rate compared with other promotes the medicine that the injury of the bone heals of invigorating blood circulation is high, total effective rate is 99%, and successful is better than matched group, and the external application ointment of invigorating blood circulation of this invention is cheap, ordinary people life-time service, also can not increase health and pecuniary burden.A routine side effect profile is there is not in clinical experiment, safety is far above the similar Chinese and western drugs promoting injury of the bone healing, and instant effect, making the healing of chronic bronchitis be no longer can to ask and unavailable, is promote that the injury of the bone heals ideal safe external application ointment of invigorating blood circulation at present.

Claims (10)

1. the external application ointment of invigorating blood circulation promoting the injury of the bone to heal, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 5-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 8-17 part, Rhizoma Cimicifugae 6-12 part, Cortex Periplocae 5-15 part, Radix Notoginseng 6-10 part, Herba Taraxaci 5-15 part, Rhizoma Coptidis 10-14 part, Radix Clematidis 7-13 part, Herba Lycopodii 8-14 part, Radix Aconiti Lateralis Preparata 3-9 part, Fructus Cnidii 4-11 part, Herba Solidaginis 9-16 part, Herba speranskiae tuberculatae 3-8 part, Rhizoma Dioscoreae Nipponicae 8-15 part, Eupolyphaga Seu Steleophaga 2-4 part, Radix et Rhizoma Dysosmatis 6-8 part, Herba Leibnitziae 5-7 part, Flos Lonicerae 15-18 part.
2. the external application ointment of invigorating blood circulation of promotion injury of the bone healing according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 8-13 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 12-14 part, Rhizoma Cimicifugae 8-10 part, Cortex Periplocae 8-13 part, Radix Notoginseng 7-9 part, Herba Taraxaci 8-13 part, Rhizoma Coptidis 11-13 part, Radix Clematidis 9-11 part, Herba Lycopodii 10-12 part, Radix Aconiti Lateralis Preparata 5-7 part, Fructus Cnidii 6-9 part, Herba Solidaginis 11-15 part, Herba speranskiae tuberculatae 4-7 part, Rhizoma Dioscoreae Nipponicae 10-13 part, Eupolyphaga Seu Steleophaga 2.5-3.5 part, Radix et Rhizoma Dysosmatis 6.5-7.5 part, Herba Leibnitziae 5.5-6.5 part, Flos Lonicerae 16-17 part.
3. the external application ointment of invigorating blood circulation of promotion injury of the bone healing according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 11 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 13 parts, Rhizoma Cimicifugae 9 parts, Cortex Periplocae 12 parts, Radix Notoginseng 8 parts, Herba Taraxaci 11.5 parts, Rhizoma Coptidis 12 parts, Radix Clematidis 10 parts, Herba Lycopodii 11 parts, Radix Aconiti Lateralis Preparata 6 parts, Fructus Cnidii 7.5 parts, Herba Solidaginis 13 parts, Herba speranskiae tuberculatae 5 parts, Rhizoma Dioscoreae Nipponicae 11.5 parts, Eupolyphaga Seu Steleophaga 3 parts, Radix et Rhizoma Dysosmatis 7 parts, Herba Leibnitziae 6 parts, Flos Lonicerae 16.5 parts.
4. the preparation method of the external application ointment of invigorating blood circulation of the promotion injury of the bone healing according to any one of claim 1-3, is characterized in that: step is as follows:
1. get Eupolyphaga Seu Steleophaga to clean, drain away the water, get Eupolyphaga Seu Steleophaga weight 1-3 edible oil doubly, put into the hot pot dryouied, drop into Eupolyphaga Seu Steleophaga, frying 3-7 minute when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;
2. Rhizoma Chuanxiong, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 80-120 mesh sieve stand-by;
3. Rhizoma Cimicifugae, Cortex Periplocae, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, and slightly stewing 5-15 hour, takes out and drain yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;
4. Radix Clematidis, Herba Lycopodii, Radix Aconiti Lateralis Preparata, Fructus Cnidii, Herba Solidaginis, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 20-40 minute, cover lid, at decoction 5-15 minute, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 4-8 days in the sunlight, dries 10-20 minute slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;
5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Add Cera Flava after thick paste being heated to 30-40 DEG C, after Cera Flava dissolves completely, bottle and obtain ointment.
5. the preparation method of external application ointment of invigorating blood circulation according to claim 4, is characterized in that: 1. step gets Eupolyphaga Seu Steleophaga weight 1.5-2.5 edible oil doubly (preferred, to get the edible oil of Eupolyphaga Seu Steleophaga weight 2 times).
6. the preparation method of external application ointment of invigorating blood circulation according to claim 4, is characterized in that: step 2. fine powder crosses 90-110 mesh sieve (preferred, fine powder, crosses 100 mesh sieves).
7. the preparation method of external application ointment of invigorating blood circulation according to claim 4, is characterized in that: step is slightly stewing 8-13 hour 3., takes out and drains yellow wine (preferred, slightly stewing 10 hours, to take out and drain yellow wine).
8. the preparation method of external application ointment of invigorating blood circulation according to claim 4, is characterized in that: 4. step decocts with water to boiling, turns slow fire boiling 25-35 minute (preferred, to decoct with water to boiling, turn slow fire boiling 30 minutes).
9. the preparation method of external application ointment of invigorating blood circulation according to claim 4, it is characterized in that: step 4. filtering residue is exposed to the sun 5-7 days in the sunlight, slowly dry 13-18 minute (preferred, filtering residue is exposed to the sun 6 days in the sunlight, be placed in little fire on iron plate dry 15 minutes slowly) being placed in little fire on iron plate.
10. the preparation method of external application ointment of invigorating blood circulation according to claim 4, is characterized in that: step adds Cera Flava (preferred, to add Cera Flava after thick paste being heated to 35 DEG C) after 5. thick paste being heated to 33-38 DEG C.
CN201510141519.6A 2015-03-30 2015-03-30 Blood activating external application ointment for promoting injured bone healing and preparation method thereof Pending CN104689078A (en)

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