CN104684556A - 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 - Google Patents

通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 Download PDF

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Publication number
CN104684556A
CN104684556A CN201380046758.2A CN201380046758A CN104684556A CN 104684556 A CN104684556 A CN 104684556A CN 201380046758 A CN201380046758 A CN 201380046758A CN 104684556 A CN104684556 A CN 104684556A
Authority
CN
China
Prior art keywords
bladder
trospium
days
trospium cation
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380046758.2A
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English (en)
Chinese (zh)
Inventor
丹尼斯·吉辛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Liris Biomedical Inc
Original Assignee
Taris Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taris Biomedical Inc filed Critical Taris Biomedical Inc
Priority to CN202010161062.6A priority Critical patent/CN111450093A/zh
Publication of CN104684556A publication Critical patent/CN104684556A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
CN201380046758.2A 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 Pending CN104684556A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010161062.6A CN111450093A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261702576P 2012-09-18 2012-09-18
US61/702,576 2012-09-18
PCT/US2013/060479 WO2014047221A1 (en) 2012-09-18 2013-09-18 Drug delivery systems and methods for treatment of bladder voiding dysfunction|and other lower urinary tract disorders by using trospium

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202010161062.6A Division CN111450093A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法

Publications (1)

Publication Number Publication Date
CN104684556A true CN104684556A (zh) 2015-06-03

Family

ID=49301639

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201380046758.2A Pending CN104684556A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法
CN202010161062.6A Pending CN111450093A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法

Family Applications After (1)

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CN202010161062.6A Pending CN111450093A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法

Country Status (13)

Country Link
US (2) US10500200B2 (https=)
EP (1) EP2897616A1 (https=)
JP (2) JP6600256B2 (https=)
KR (1) KR102141433B1 (https=)
CN (2) CN104684556A (https=)
AU (1) AU2013318146B2 (https=)
BR (1) BR112015005351A2 (https=)
CA (1) CA2883855C (https=)
IL (1) IL237498B (https=)
MX (2) MX379066B (https=)
RU (1) RU2670749C9 (https=)
SG (1) SG11201502104YA (https=)
WO (1) WO2014047221A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112839653A (zh) * 2018-08-01 2021-05-25 塔里斯生物医药公司 使用曲司氯铵治疗膀胱过度活动症的方法
CN113939277A (zh) * 2019-04-30 2022-01-14 特瑞纲制药有限公司 用于药物输注到膀胱中和治疗膀胱疾病的制剂和方法

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LT4124339T (lt) 2014-03-06 2025-11-10 Vaisto įvedimo sistemos ir būdai šlapimo pūslės vėžiui gydyti gemcitabinu
CN106573133B (zh) * 2014-08-19 2020-03-03 加利福尼亚大学董事会 用于局部药物递送的植入物及其使用方法
GB201506526D0 (en) 2015-04-17 2015-06-03 Uropharma Ltd And Synesis Llc Medicinal composition
CN106706832A (zh) * 2015-08-06 2017-05-24 舒泰神（北京）生物制药股份有限公司 一种测定曲司氯铵含量的方法
PT3432970T (pt) 2017-02-01 2021-05-26 Taris Biomedical Llc Dispositivos de administração de fármaco in vivo
BR112020000832A2 (pt) 2017-07-25 2020-07-21 Taris Biomedical Llc métodos para tratar metástase tumoral
TWI841554B (zh) 2018-03-21 2024-05-11 丹麥商珍美寶股份有限公司 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法
WO2019217455A1 (en) 2018-05-07 2019-11-14 Genmab A/S Methods of treating cancer with a combination of an anti-pd-1 antibody and an anti-tissue factor antibody-drug conjugate
TWI844571B (zh) 2018-10-30 2024-06-11 丹麥商珍美寶股份有限公司 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法
US11173291B2 (en) 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
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US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112839653A (zh) * 2018-08-01 2021-05-25 塔里斯生物医药公司 使用曲司氯铵治疗膀胱过度活动症的方法
CN113939277A (zh) * 2019-04-30 2022-01-14 特瑞纲制药有限公司 用于药物输注到膀胱中和治疗膀胱疾病的制剂和方法
CN113939277B (zh) * 2019-04-30 2024-04-09 特瑞纲制药有限公司 用于药物输注到膀胱中和治疗膀胱疾病的制剂和方法

Also Published As

Publication number Publication date
JP2015529688A (ja) 2015-10-08
CA2883855C (en) 2020-09-15
JP6600256B2 (ja) 2019-10-30
IL237498B (en) 2018-01-31
CN111450093A (zh) 2020-07-28
CA2883855A1 (en) 2014-03-27
BR112015005351A2 (pt) 2017-07-04
IL237498A0 (en) 2015-04-30
RU2015112196A (ru) 2016-11-10
MX2020002465A (es) 2020-07-13
WO2014047221A9 (en) 2015-05-21
SG11201502104YA (en) 2015-05-28
JP2018080208A (ja) 2018-05-24
WO2014047221A1 (en) 2014-03-27
EP2897616A1 (en) 2015-07-29
AU2013318146B2 (en) 2018-05-10
RU2670749C2 (ru) 2018-10-25
KR20150058271A (ko) 2015-05-28
RU2670749C9 (ru) 2018-12-13
MX2015003110A (es) 2015-06-05
US20150182516A1 (en) 2015-07-02
MX379066B (es) 2025-03-04
AU2013318146A1 (en) 2015-03-19
US20200108057A1 (en) 2020-04-09
KR102141433B1 (ko) 2020-08-05
US11850244B2 (en) 2023-12-26
US10500200B2 (en) 2019-12-10

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Application publication date: 20150603

RJ01 Rejection of invention patent application after publication