BR112015005351A2 - sistemas para distribuição de drogas e métodos para tratamento de disfunção de esvaziamento da bexiga e outros distúrbios do trato urinário inferior - Google Patents
sistemas para distribuição de drogas e métodos para tratamento de disfunção de esvaziamento da bexiga e outros distúrbios do trato urinário inferiorInfo
- Publication number
- BR112015005351A2 BR112015005351A2 BR112015005351A BR112015005351A BR112015005351A2 BR 112015005351 A2 BR112015005351 A2 BR 112015005351A2 BR 112015005351 A BR112015005351 A BR 112015005351A BR 112015005351 A BR112015005351 A BR 112015005351A BR 112015005351 A2 BR112015005351 A2 BR 112015005351A2
- Authority
- BR
- Brazil
- Prior art keywords
- bladder
- methods
- drug delivery
- trospium
- delivery systems
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 208000026723 Urinary tract disease Diseases 0.000 title abstract 2
- 230000004064 dysfunction Effects 0.000 title abstract 2
- 208000014001 urinary system disease Diseases 0.000 title abstract 2
- OYYDSUSKLWTMMQ-JKHIJQBDSA-N trospium Chemical compound [N+]12([C@@H]3CC[C@H]2C[C@H](C3)OC(=O)C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CCCC1 OYYDSUSKLWTMMQ-JKHIJQBDSA-N 0.000 abstract 4
- 229960001491 trospium Drugs 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 206010069632 Bladder dysfunction Diseases 0.000 abstract 1
- 210000005068 bladder tissue Anatomy 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261702576P | 2012-09-18 | 2012-09-18 | |
| PCT/US2013/060479 WO2014047221A1 (en) | 2012-09-18 | 2013-09-18 | Drug delivery systems and methods for treatment of bladder voiding dysfunction|and other lower urinary tract disorders by using trospium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015005351A2 true BR112015005351A2 (pt) | 2017-07-04 |
Family
ID=49301639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015005351A BR112015005351A2 (pt) | 2012-09-18 | 2013-09-18 | sistemas para distribuição de drogas e métodos para tratamento de disfunção de esvaziamento da bexiga e outros distúrbios do trato urinário inferior |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10500200B2 (https=) |
| EP (1) | EP2897616A1 (https=) |
| JP (2) | JP6600256B2 (https=) |
| KR (1) | KR102141433B1 (https=) |
| CN (2) | CN104684556A (https=) |
| AU (1) | AU2013318146B2 (https=) |
| BR (1) | BR112015005351A2 (https=) |
| CA (1) | CA2883855C (https=) |
| IL (1) | IL237498B (https=) |
| MX (2) | MX379066B (https=) |
| RU (1) | RU2670749C9 (https=) |
| SG (1) | SG11201502104YA (https=) |
| WO (1) | WO2014047221A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| JP6463266B2 (ja) | 2012-08-31 | 2019-01-30 | タリス バイオメディカル エルエルシー | 膀胱癌の治療のためのオキサリプラチンを含む薬物送達システム及び方法 |
| AU2013308465B2 (en) | 2012-08-31 | 2018-05-17 | Taris Biomedical Llc | Drug delivery systems and methods for treatment of prostate disease comprising gemicitabine |
| BR112015005351A2 (pt) * | 2012-09-18 | 2017-07-04 | Taris Biomedical Llc | sistemas para distribuição de drogas e métodos para tratamento de disfunção de esvaziamento da bexiga e outros distúrbios do trato urinário inferior |
| US20150250717A1 (en) | 2014-03-06 | 2015-09-10 | Taris Biomedical Llc | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
| US10912933B2 (en) | 2014-08-19 | 2021-02-09 | The Regents Of The University Of California | Implants for localized drug delivery and methods of use thereof |
| GB201506526D0 (en) | 2015-04-17 | 2015-06-03 | Uropharma Ltd And Synesis Llc | Medicinal composition |
| CN106706832A (zh) * | 2015-08-06 | 2017-05-24 | 舒泰神（北京）生物制药股份有限公司 | 一种测定曲司氯铵含量的方法 |
| SG11201907033SA (en) | 2017-02-01 | 2019-08-27 | Taris Biomedical Llc | In vivo drug delivery devices and methods for drug delivery |
| SG10201913998YA (en) | 2017-07-25 | 2020-03-30 | Taris Biomedical Llc | Methods of treating tumor metastasis |
| TWI841554B (zh) | 2018-03-21 | 2024-05-11 | 丹麥商珍美寶股份有限公司 | 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法 |
| TW202506732A (zh) | 2018-05-07 | 2025-02-16 | 丹麥商珍美寶股份有限公司 | 使用抗ｐｄ－１抗體與抗組織因子抗體－藥物共軛體之組合以治療癌症之方法 |
| CN112839653A (zh) * | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
| TWI844571B (zh) | 2018-10-30 | 2024-06-11 | 丹麥商珍美寶股份有限公司 | 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法 |
| CN113939277B (zh) * | 2019-04-30 | 2024-04-09 | 特瑞纲制药有限公司 | 用于药物输注到膀胱中和治疗膀胱疾病的制剂和方法 |
| CN115515657A (zh) | 2020-03-20 | 2022-12-23 | 加利福尼亚大学董事会 | 用于局部药物递送的可植入药物递送设备 |
| US11344526B2 (en) | 2020-03-20 | 2022-05-31 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11338119B2 (en) | 2020-03-20 | 2022-05-24 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11173291B2 (en) | 2020-03-20 | 2021-11-16 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| KR102596697B1 (ko) | 2021-05-20 | 2023-11-01 | 김정우 | 바위솔 추출물을 유효성분으로 포함하는 화장품 조성물 및 그 제조 방법 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE172117T1 (de) * | 1996-11-27 | 1998-10-15 | Pfleger R Chem Fab | Verwendung von trospiumchlorid zur herstellung eines arzneimittels zur behandlung von blasenkrankheiten |
| EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
| WO2004052440A1 (en) * | 2002-12-11 | 2004-06-24 | Coloplast A/S | A urinary catheter device with a pharmaceutically active composition |
| AU2004206846B2 (en) | 2003-01-16 | 2009-05-28 | University Of Rochester | Quaternary antimuscarinic compounds for the treatment of bladder diseases |
| ES2322148T3 (es) | 2004-08-11 | 2009-06-17 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Medicamentos que contienen anticolinergicos para el tratamiento en las vias urinarias. |
| US20060217405A1 (en) * | 2005-03-17 | 2006-09-28 | Indevus Pharmaceuticals, Inc. | Interstitial cystitis treatment |
| US7390816B2 (en) | 2005-06-21 | 2008-06-24 | Bridge Pharma, Inc. | Methods for treating urinary incontinence in patients suffering from memory disorders |
| JP5265359B2 (ja) | 2005-08-11 | 2013-08-14 | マサチューセッツ インスティテュート オブ テクノロジー | 膀胱内薬物送達デバイスおよび方法 |
| EP1967202A1 (en) | 2007-03-05 | 2008-09-10 | AEterna Zentaris GmbH | Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity |
| US9586035B2 (en) * | 2007-12-11 | 2017-03-07 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens |
| EA201170297A1 (ru) | 2008-08-09 | 2011-08-30 | Массачусетс Инститьют Оф Текнолоджи | Имплантируемое устройство для доставки лекарственных средств и способ лечения мужской мочеполовой системы и окружающих тканей |
| CN102470237A (zh) | 2009-06-26 | 2012-05-23 | 塔里斯生物医药公司 | 用于可植入药物递送装置的固体药物片剂 |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| PL3884988T3 (pl) | 2009-12-17 | 2025-09-08 | Taris Biomedical Llc | Urządzenie implantowalne z tolerancją wewnątrzpęcherzową |
| US20110218488A1 (en) | 2010-03-05 | 2011-09-08 | Taris Biomedical, Inc. | Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites |
| JP5945544B2 (ja) | 2010-10-06 | 2016-07-05 | タリス バイオメディカル エルエルシー | 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法 |
| US9457176B2 (en) | 2010-10-06 | 2016-10-04 | Taris Biomedical Llc | Implantable drug delivery device with bladder retention feature |
| US9114111B2 (en) | 2011-01-10 | 2015-08-25 | Allergan, Inc. | Methods for sustained treatment of bladder pain and irritative voiding |
| AU2012211960B2 (en) | 2011-02-04 | 2016-12-01 | Taris Biomedical Llc | Implantable device for controlled release of low solubility drug |
| BR112015005351A2 (pt) * | 2012-09-18 | 2017-07-04 | Taris Biomedical Llc | sistemas para distribuição de drogas e métodos para tratamento de disfunção de esvaziamento da bexiga e outros distúrbios do trato urinário inferior |
| PT2968880T (pt) | 2013-03-15 | 2025-07-07 | Taris Biomedical Llc | Dispositivos de aplicação de fármaco com componente permeável a fármaco |
-
2013
- 2013-09-18 BR BR112015005351A patent/BR112015005351A2/pt not_active Application Discontinuation
- 2013-09-18 RU RU2015112196A patent/RU2670749C9/ru active
- 2013-09-18 CN CN201380046758.2A patent/CN104684556A/zh active Pending
- 2013-09-18 CN CN202010161062.6A patent/CN111450093A/zh active Pending
- 2013-09-18 WO PCT/US2013/060479 patent/WO2014047221A1/en not_active Ceased
- 2013-09-18 EP EP13771696.5A patent/EP2897616A1/en active Pending
- 2013-09-18 AU AU2013318146A patent/AU2013318146B2/en not_active Ceased
- 2013-09-18 KR KR1020157008403A patent/KR102141433B1/ko active Active
- 2013-09-18 JP JP2015532177A patent/JP6600256B2/ja active Active
- 2013-09-18 MX MX2015003110A patent/MX379066B/es unknown
- 2013-09-18 CA CA2883855A patent/CA2883855C/en active Active
- 2013-09-18 SG SG11201502104YA patent/SG11201502104YA/en unknown
-
2015
- 2015-03-02 IL IL237498A patent/IL237498B/en active IP Right Grant
- 2015-03-11 MX MX2020002465A patent/MX2020002465A/es unknown
- 2015-03-16 US US14/658,699 patent/US10500200B2/en active Active
-
2018
- 2018-02-02 JP JP2018017300A patent/JP2018080208A/ja active Pending
-
2019
- 2019-12-06 US US16/706,009 patent/US11850244B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015003110A (es) | 2015-06-05 |
| KR102141433B1 (ko) | 2020-08-05 |
| CN104684556A (zh) | 2015-06-03 |
| US20150182516A1 (en) | 2015-07-02 |
| WO2014047221A1 (en) | 2014-03-27 |
| SG11201502104YA (en) | 2015-05-28 |
| RU2015112196A (ru) | 2016-11-10 |
| KR20150058271A (ko) | 2015-05-28 |
| RU2670749C2 (ru) | 2018-10-25 |
| AU2013318146B2 (en) | 2018-05-10 |
| US20200108057A1 (en) | 2020-04-09 |
| CA2883855A1 (en) | 2014-03-27 |
| US11850244B2 (en) | 2023-12-26 |
| JP2018080208A (ja) | 2018-05-24 |
| AU2013318146A1 (en) | 2015-03-19 |
| MX379066B (es) | 2025-03-04 |
| IL237498B (en) | 2018-01-31 |
| MX2020002465A (es) | 2020-07-13 |
| JP2015529688A (ja) | 2015-10-08 |
| EP2897616A1 (en) | 2015-07-29 |
| CA2883855C (en) | 2020-09-15 |
| RU2670749C9 (ru) | 2018-12-13 |
| JP6600256B2 (ja) | 2019-10-30 |
| WO2014047221A9 (en) | 2015-05-21 |
| US10500200B2 (en) | 2019-12-10 |
| IL237498A0 (en) | 2015-04-30 |
| CN111450093A (zh) | 2020-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |