CN104666926A

CN104666926A - Hypertension improving agent

Info

Publication number: CN104666926A
Application number: CN201310630228.4A
Authority: CN
Inventors: 赖虹杜
Original assignee: Shaanxi Health And Happiness Chinese Medicine Health Preserving Academy
Current assignee: Shaanxi Health And Happiness Chinese Medicine Health Preserving Academy
Priority date: 2013-12-02
Filing date: 2013-12-02
Publication date: 2015-06-03

Abstract

The invention relates to a hypertension improving agent which is prepared from the following traditional Chinese medicinal materials in parts by weight: 10-15 parts of salviae miltiorrhizae, 6-10 parts of selfheal, 10-20 parts of mulberry leaves, 10-15 parts of bunge cherry seeds, 6-10 parts of spina date seeds, 8-15 parts of artemisia capillaries, 10-15 parts of cortex lycii radicis, 6-10 parts of cortex mori radicis and 6-10 parts of dendrobe. The hypertension improving agent is prepared from the following traditional Chinese medicinal materials in parts by weight: 12 parts of salviae miltiorrhizae, 8 parts of selfheal, 15 parts of mulberry leaves, 12 parts of bunge cherry seeds, 8 parts of spina date seeds, 12 parts of artemisia capillaries, 10 parts of cortex lycii radicis, 8 parts of cortex mori radicis and 8 parts of dendrobe. The hypertension improving agent is capable of improving the disease, treating hypertension and minimizing side effects. The hypertension improving agent aims at effectively lowering the blood pressure of patients, reducing side effects, calming the liver, and suppressing yang.

Description

A kind of hypertension-ameliorating agent

Technical field

The present invention relates to a kind of hypertension-ameliorating agent.

Background technology

Hypertension is a kind of a kind of commonly encountered diseases affecting health of people, harm humans.In state-owned 11% people suffer from hypertension, the whole world has the people of 10% to suffer from hypertension, and patient presses the speed increase of 1.5-2% every year.Suffers from the generation that hypertension often can cause Other diseases; countries in the world medical worker is all at the hypertensive active drug of development treatment; although the antihypertensive drug kind of current Clinical practice is more; but due to weak effect during single drug; side effect is more; general employing several drugs use in conjunction, and need take throughout one's life, bring a lot of inconvenience to the life of patient.

Therefore, we need a kind of few side effects, safely and effectively depressor.

Summary of the invention

The invention provides a kind of hypertension-ameliorating agent, improve and treat hypertension, and allow minimize side effects, the object of the invention is to effectively to reduce patients' blood and blood glucose, the generation of minimizing side effect, suppressing the hyperactive liver and subsiding YANG.

For this reason, the invention provides following Chinese medicine: comprise Radix Salviae Miltiorrhizae 10-15 part, Spica Prunellae 6-10 part, Folium Mori 10-20 part, Semen Pruni 10-15 part, Semen Ziziphi Spinosae 6-10 part, Herba Artemisiae Scopariae 8-15 part, Cortex Lycii 10-15 part, Cortex Mori 6-10 part, Herba Dendrobii 6-10 part.

Above-mentioned Chinese medicine is formed by following weight parts raw material of Chinese medicine medicine system of closing: Radix Salviae Miltiorrhizae 12 parts, Spica Prunellae 8 parts, 15 parts, Folium Mori, Semen Pruni 12 parts, Semen Ziziphi Spinosae 8 parts, Herba Artemisiae Scopariae 12 parts, Cortex Lycii 10 parts, Cortex Mori 8 parts, Herba Dendrobii 8 parts.

Medical material selected by the present invention and pharmacology as follows:

Radix Salviae Miltiorrhizae: bitter, be slightly cold.GUIXIN, Liver Channel.Can coronary artery dilator, increase coronary flow, improve core ischemia, infraction and cardiac function, the formation of thrombosis can be suppressed, improve microcirculation, promote liver cell regeneration, blood fat, blood glucose can be reduced.

Spica Prunellae: bitter, acrid, cold.Return liver, gallbladder meridian.Inorganic salt part has hypotensive effect; Decoct can reduce blood pressure and mitigation symptoms clinically.

Folium Mori: Folium Mori: bitter, sweet, cold.Return lung, Liver Channel.Dispelling wind and heat pathogens, liver heat removing and eyesight improving (processed with honey is longer than nourishing the lung to arrest cough).Reduce blood pressure and diuresis; Have zoopery hyperglycemia and fall hypoglycemic effect.

Semen Pruni: pungent, bitter, sweet, flat.Return spleen, large intestine, small intestine meridian.Moisturize laxation, the therapeutic method to keep the adverse QI flowing downwards, diuretic.Anemia of pregnant woman is cautious use of.Semen Pruni tincture has obvious hypotensive activity.

Semen Ziziphi Spinosae: sweet, sour is flat.GUIXIN, liver, gallbladder, spleen channel.Tranquilizing by nourishing the heart, arresting sweating.This product is important alimentary sedative.There are calmness, syngignoscism.Can reduce blood pressure and suppress the formation of animal renal hypertension.

Herba Artemisiae Scopariae: bitter, pungent, be slightly cold.Return spleen, stomach, liver, gallbladder meridian.Clearing away damp-heat, jaundice eliminating subcutaneous ulcer.Treatment hepatitis drug of first choice.Treatment hyperlipemia and coronary heart disease.Again for cholelithiasis, normal and Radix Et Rhizoma Rhei, Herba Lysimachiae, Radix Curcumae etc.Function of gallbladder promoting is had to protect the liver, blood fat reducing, blood pressure lowering and antibacterial action.

Cortex Mori: sweet, cold.Return lung meridian.Eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.Have hypotensive effect, it is effective that modern age is used for hypertension.There is diuresis, comparatively polychloride can be taken out of, and have calmness and hypotensive effect.

Cortex Lycii: sweet, cold.Return lung, kidney channel.Removing heat from blood moves back steaming, eliminating heat from the lung.Preserved material, decoct, tincture and injection all have obvious hypotensive effect.Slight hypoglycemic activity is had to rabbit.And have the effect reducing serum total cholesterol content.

Herba Dendrobii: sweet, light, is slightly cold.Attach to the lung and stomach meridians.Reinforcing stomach reg fluid, replenishing YIN and removing heat.This product also has the effect of improving eyesight and strong waist knee joint.Dendrobine can cause the medium degree hyperglycemia of laboratory animal, and heavy dose of have inhibitory action to heart, breathing, and can reduce blood pressure.

Medicine of the present invention based on suppressing the hyperactive liver and subsiding YANG, nourishing the liver and kidney, eliminate the phlegm and invigorate blood circulation, and have vessel softening, reduce blood glucose, enhancing human body immunity power effect, be mainly used in reduce hypertension.

Detailed description of the invention

Embodiment 1:

Filter out Radix Salviae Miltiorrhizae 12 parts, Spica Prunellae 8 parts, 15 parts, Folium Mori, Semen Pruni 12 parts, Semen Ziziphi Spinosae 8 parts, Herba Artemisiae Scopariae 12 parts, Cortex Lycii 10 parts, Cortex Mori 8 parts, Herba Dendrobii 8 parts, 30 parts are divided into be the consumption of month, every day gets portion and decocts, cold water soak 20 minutes are first used before decoction, pulled out into marmite, after the cold water of medical material 3 times of reinjecting boils with high heat, use slow fire instead and simmer 30 minutes, midway need stir twice.After cooked, take concoction, every agent medicine can decoction twice.Second time injects the water continuation decoction of 2 times, and decocting time can shorten 10 points of kinds.Sooner or later service once, contraindication in pregnancy.

Embodiment 2:

After filtering out Radix Salviae Miltiorrhizae 12 parts, Spica Prunellae 8 parts, 15 parts, Folium Mori, Semen Pruni 12 parts, Semen Ziziphi Spinosae 8 parts, Herba Artemisiae Scopariae 12 parts, Cortex Lycii 10 parts, Cortex Mori 8 parts, Herba Dendrobii 8 parts, drying and crushing crosses 120 mesh sieves, add Mel and make big honeyed pills agent, be divided into 30 parts, every day is a.

Embodiment 3:

Filter out Radix Salviae Miltiorrhizae 12 parts, Spica Prunellae 8 parts, 15 parts, Folium Mori, Semen Pruni 12 parts, Semen Ziziphi Spinosae 8 parts, Herba Artemisiae Scopariae 12 parts, Cortex Lycii 10 parts, Cortex Mori 8 parts, Herba Dendrobii 8 parts, crushed after being dried becomes fine powder, crosses 120 mesh sieves, with water pill, dry sepia watered pill, is divided into 30 parts.Oral, three times on the one, warm water takes.

clinical experiment is observed:

(1) Therapeutic Method:

Select age 48-58 year patient 100 example, 55 years old mean age ,-1 year April of the course of disease, average course of disease 7 months.Patient did not accept other treatment before this treatment, surveyed its blood pressure and all exceeded normal value.Within 30 days, be a course for the treatment of, after 30 days, carry out symptom score.

Treatment group 1(20 people): the medicine giving the embodiment of the present invention one, take one month.

Treatment group 2(20 people): the medicine giving the embodiment of the present invention two, take one month.

Treatment group 3(20 people): the medicine giving the embodiment of the present invention three, take one month.

Control group A (20 people): take conventional western medicine valsartan and carry out blood pressure lowering.

Matched group B(20 people): do not take any medicine.

(2) efficacy assessment standard:

Cure: clinical symptoms all disappears, high pressure≤120-140mm/Hg, low pressure≤80-90 mm/Hg, and drug withdrawal two months blood pressures do not rebound;

Effective: clinical symptoms disappears substantially, high pressure≤120-140mm/Hg, low pressure≤80-90 mm/Hg; Invalid: to compare with before treatment, the unchanged or exacerbation of symptoms of every Physico-chemical tests index.

Bounce-back: measure high pressure blood pressure after referring to drug withdrawal and be all greater than normal value 140/90mmHg.

(3) therapeutic outcome sees the following form:

Detect the safety indexes for the treatment of group patient, do not find liver, kidney, core function abnormality, hematuria just checks and meets conventional criteria.Treatment group 1, treatment group 2 and treatment group 3 strictly press prescriptions, medication 1 month, successful, and with blood glucose reduce effect, it is high that control group A takes common Western medicine blood pressure lowering rebound rate, and have the people of 5% occur edema, faint, insomnia side effect.

Claims

1. a hypertension-ameliorating agent, is characterized in that: the present invention comprises Radix Salviae Miltiorrhizae 10-15 part, Spica Prunellae 6-10 part, Folium Mori 10-20 part, Semen Pruni 10-15 part, Semen Ziziphi Spinosae 6-10 part, Herba Artemisiae Scopariae 8-15 part, Cortex Lycii 10-15 part, Cortex Mori 6-10 part, Herba Dendrobii 6-10 part.

2. hypertension-ameliorating agent according to claim 1, is characterized in that: it is formed by following weight parts raw material of Chinese medicine medicine system of closing: Radix Salviae Miltiorrhizae 12 parts, Spica Prunellae 8 parts, 15 parts, Folium Mori, Semen Pruni 12 parts, Semen Ziziphi Spinosae 8 parts, Herba Artemisiae Scopariae 12 parts, Cortex Lycii 10 parts, Cortex Mori 8 parts, Herba Dendrobii 8 parts.