CN104666178B - A kind of skin whitening, moisturizing composition and facial mask - Google Patents
A kind of skin whitening, moisturizing composition and facial mask Download PDFInfo
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- 230000001815 facial effect Effects 0.000 title claims abstract description 35
- 239000000203 mixture Substances 0.000 title claims abstract description 33
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 22
- 230000002087 whitening effect Effects 0.000 title claims abstract description 22
- 239000000284 extract Substances 0.000 claims abstract description 36
- 240000007817 Olea europaea Species 0.000 claims abstract description 35
- 235000002725 Olea europaea Nutrition 0.000 claims abstract description 35
- 238000002360 preparation method Methods 0.000 claims abstract description 34
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Abstract
The invention provides a kind of skin whitening, moisturizing composition, and it is the external preparation being prepared with the raw material of following weight proportion：5~50 parts of licorice, 5~50 parts of Olive leaf P.E, 5~50 parts of green-tea extract, 1~10 part of Gentrin Knotweed P.E.Present invention also offers a kind of facial mask and preparation method thereof.Largely the as shown by data present composition on probation has significant moisturizing, highlighted, white-skinned face function, simultaneously, said composition is by each herb extract reasonable compatibility, synergistic function is played, with more significantly active, there is provided a kind of that there is moisturizing, highlight, the new skin care item of Bearberry Extract.
Description
Technical field
The present invention relates to a kind of skin whitening, moisturizing composition and facial mask.
Background technology
In current skin care item product, it is main the effect of concentrate on whitening, moisturizing, nti-freckle, anti-aging etc..With right
Herbal understanding is constantly deepened, and also occurs the skin care item based on herbaceous plant extract at present.
It was discovered by researchers that after acting on skin using some herbaceous plant extracts, by metabolism, can reach
Beautification or the effect for repairing skin.Such as Chinese patent：201310046660.9 disclose a kind of combination of anti aging effect
Thing, it is that have Chinese rhubarb extract, purslane extract, kudzu root extract, glutinous rehmannia extract and ginkgo biloba p.e to be prepared；
And for example Chinese patent：201210553154.4, disclose a kind of skin lightening compositions, it be by ginseng, saline cistanche, Radix Angelicae Sinensis,
The extract such as ginkgo leaf and rhodiola root is prepared.
The content of the invention
It is an object of the invention to provide a kind of skin whitening, moisturizing composition based on herbaceous plant extract.The present invention's is another
One purpose is to provide a kind of whitening moisturizing face masque.
The invention provides a kind of skin whitening, moisturizing composition, and it is the external application being prepared with the raw material of following weight proportion
Preparation：
5~50 parts of licorice, 5~50 parts of Olive leaf P.E, 5~50 parts of green-tea extract, Gentrin Knotweed P.E 1~
10 parts.
Preferably, raw material proportioning is as follows：12 parts of licorice, 12 parts of Olive leaf P.E, 10 parts of green-tea extract, tiger
5 parts of cane extract.
Wherein, in the licorice, general flavone content is not less than 10mg/g, and total saponin content is not less than 40mg/g；
In the Olive leaf P.E, hydroxytyrosol content is not less than 80mg/g；In the green-tea extract, catechin content is not less than
400mg/g, EGCG are not less than 130mg/g；In the Gentrin Knotweed P.E, Resveratrol content
Not less than 400mg/g.
Further, in the licorice, general flavone content 17.8mg/g, total saponin content 55mg/g；It is described
In Olive leaf P.E, hydroxytyrosol content 100mg/g；In the green-tea extract, catechin content 500mg/g, table does not have
Gallate-based catechin and gallate 150mg/g；In the Gentrin Knotweed P.E, resveratrol 500mg/g.
Wherein, the preparation method of the extract is as follows：
The preparation of licorice：Radix glycyrrhizae is weighed, adds water refluxing extraction, merges extract solution, is filtered, is concentrated, dries, produces
Licorice；
The preparation of green-tea extract：Green tea is taken, is extracted using 70%v/v alcohol refluxs, after extract solution recovery ethanol, then is used
HPD-600 macroreticular resins carry out adsorption and purification, are eluted using 80%v/v ethanol, collect ethanol eluate, reclaim ethanol,
Concentration, dry, produce green-tea extract；
The preparation of Olive leaf P.E：Olive leaf is taken, is extracted using 90%v/v alcohol refluxs, after extract solution recovery ethanol,
Purified using AB-8 macroporous resin adsorptions, eluent is made with 70%v/v ethanol and then collects efflux, after reclaiming ethanol, used
The extraction of ethyl acetate-water system, collects ethyl acetate layer, with silica gel post separation, with ethyl acetate：Ethanol=5:1 elution, is collected
Eluent, after recycling design, dry, produce Olive leaf P.E；
The preparation of Gentrin Knotweed P.E：Giant knotweed is taken, is extracted using pH=2 60%v/v EtOH Sonicates, extract solution LS-303
Macroporous absorbent resin carries out adsorption and purification, makees eluent with 70%v/v ethanol and then collects efflux, dense after reclaiming ethanol
Contracting, dry, produce Gentrin Knotweed P.E.
Wherein, the composition be using above-mentioned each extract as active component, it is auxiliary plus what is commonly used in pharmaceutically or cosmetically
The preparation for external application to skin that material or complementary composition are prepared.
Further, the complementary composition is hyaluronic acid.
Wherein, the external preparation is face cream, emulsion, gel, toner, Essence or facial mask.
Present invention also offers a kind of whitening moisturizing face masque, per in 1000ml facial mask essences, contains following composition：
Optimum ratio is as follows：
Further, the preservative is Phenoxyethanol；The pH adjusting agent is selected from sodium citrate.
Further, the essence no more than 1g is also contained in every 1000ml facial mask essences；Preferably, per 1000ml facial masks
Also contain 0.002g essence in Essence.
Essence used in the present invention, the essence species for allowing to use in cosmetics can be chosen according to being actually needed.
Present invention also offers the preparation method of Essence in above-mentioned facial mask, and it includes following operating procedure：
1. carbomer is dissolved with water；
2. hydroxyethyl cellulose is dissolved with water, insoluble matter is filtered out, filtrate mixes with the carbomer aqueous solution, fully stirred
Mix；
3. sequentially add butanediol, propane diols and stir；
4. adding hyaluronic acid, stir, add pH adjusting agent, be sufficiently stirred；
5. licorice is added, green-tea extract, Olive leaf P.E, Gentrin Knotweed P.E stirring；
6. adding residual components, it is sufficiently stirred；
7. the solution constant volume that will have been configured, sterilizing, are produced.
Largely the as shown by data present composition on probation has significant moisturizing, highlighted, white-skinned face function, meanwhile, the group
Each herb extract reasonable compatibility has been played synergistic function by compound, is had more significantly active, there is provided one kind tool
There is moisturizing, highlight, the new skin care item of Bearberry Extract.
Embodiment
The preparation of 1 facial mask of the present invention of embodiment
1. formula
Table 1
| Sequence number | Name of material | Additional proportion (%) | 1000ml inventorys (g) |
| 1 | Propane diols | 10 | 100 |
| 2 | Butanediol | 7.5 | 75 |
| 3 | Phenoxyethanol | 0.5 | 1 |
| 4 | Carbomer | 0.2 | 2 |
| 5 | Hydroxyethyl cellulose | 0.16 | 1.6 |
| 6 | Hyaluronic acid | 0.1 | 1 |
| 7 | Sodium citrate | 0.04 | 0.4 |
| 8 | Olive leaf P.E | 0.012 | 0.12 |
| 9 | Licorice | 0.012 | 0.12 |
| 10 | Green-tea extract | 0.01 | 0.1 |
| 11 | Gentrin Knotweed P.E | 0.005 | 0.05 |
| 12 | Essence | 0.0002 | 0.002 |
2. preparation technology
1. by carbomer (20-30 DEG C) dissolving of water；
2. by hydroxyethyl cellulose (50-60 DEG C) dissolving of hot water, insoluble matter is filtered out, filtrate is mixed with the carbomer aqueous solution
Close, be sufficiently stirred；
3. sequentially add butanediol, propane diols and stir 10 minutes；
4. adding hyaluronic acid, 10min is stirred, sodium citrate is added, is sufficiently stirred；
5. licorice is added, green-tea extract, Olive leaf P.E, Gentrin Knotweed P.E stirring；
6. adding essence, preservative (Phenoxyethanol 0.5%), it is sufficiently stirred；
7. the solution constant volume that will have been configured, sterilizing, dispense, produce with face paper.
The preparation of licorice：Radix glycyrrhizae is weighed, using water as solvent, refluxing extraction 3 times at 80 DEG C, each 1.5h is dense
Contracting, dry, produce licorice.
The preparation of green-tea extract：Green tea is taken, using 70%v/v ethanol as solvent, Extracting temperature is 70 DEG C, refluxing extraction
2h, after extract solution recovery ethanol, then with HPD-600 macroreticular resins adsorption and purification is carried out, is eluted using 80%v/v ethanol,
Ethanol eluate is collected, reclaims ethanol, is concentrated, dries, produces green-tea extract.
The preparation of Olive leaf P.E：Take olive leaf, using 90%v/v alcohol-waters to olive leaf refluxing extraction three times, often
Secondary 2 hours, after extract solution recovery, purified using AB-8 macroporous resin adsorptions, eluent is made with 70%v/v ethanol and then collected
Efflux, after reclaiming ethanol, extracted using ethyl acetate-water system, collect ethyl acetate layer, with silica gel post separation, with acetic acid
Ethyl ester：Ethanol=5:1 is eluent, collection eluent, after recycling design, dries, produces Olive leaf P.E.
The preparation of Gentrin Knotweed P.E：Giant knotweed is taken, is extracted 3 times, each 30min using pH=2 60%v/v EtOH Sonicates,
Extract solution carries out adsorption and purification with LS-303 macroporous absorbent resins, makees eluent with 70%v/v ethanol and then collects efflux,
After reclaiming ethanol, concentrate, dry, produce Gentrin Knotweed P.E.
Table 2
| Title | Component content |
| Licorice | General flavone content 17.8mg/g, total saponin content 55mg/g |
| Olive leaf P.E | Hydroxytyrosol content is 100mg/g |
| Green-tea extract | Catechin content 500mg/g, EGCG 150mg/g |
| Gentrin Knotweed P.E | Resveratrol 500mg/g |
The extracting method of each bulk drug of the present invention is not limited only to the above method, by the restriction of index components, using document
Other methods of report are also alternative.
Beneficial effects of the present invention are illustrated below by way of test example.
The present composition prescription screening of test example 1 is tested
First, the preparation of different prescription experiment products
Prescription 1：
Licorice 0.039%, propane diols 10%, butanediol 7.5%, Phenoxyethanol 0.5%, carbomer 0.2%, hydroxyl
Ethyl cellulose 0.16%, hyaluronic acid 0.1%, sodium citrate 0.04%
Prescription 2：
Licorice 0.0195%, Olive leaf P.E 0.0195%, propane diols 10%, butanediol 7.5%, benzene oxygen second
Alcohol 0.5%, carbomer 0.2%, hydroxyethyl cellulose 0.16%, hyaluronic acid 0.1%, sodium citrate 0.04%
Prescription 3：
Licorice 0.012%, Olive leaf P.E 0.012%, green-tea extract 0.015%, propane diols 10%, fourth
Glycol 7.5%, Phenoxyethanol 0.5%, carbomer 0.2%, hydroxyethyl cellulose 0.16%, hyaluronic acid 0.1%, sodium citrate
0.04%
Prescription 4：
Licorice 0.012%, green-tea extract 0.01%, Olive leaf P.E 0.012%, Gentrin Knotweed P.E
0.005%th, propane diols 10%, butanediol 7.5%, Phenoxyethanol 0.5%, carbomer 0.2%, hydroxyethyl cellulose 0.16%,
Hyaluronic acid 0.1%, sodium citrate 0.04%
Above-mentioned different prescriptions are prepared into facial mask essence according to the method for embodiment 1, and take essence obtained by each prescription
Magnificent liquid phase same amount prepares facial mask, carries out following screening experiment.
2nd, whitening, highlight experiment
Study subject and method
1.1 study subject
1.1.1 the inclusion criteria of subject：1. the normal men and women subject of age 18-60 year, women are preferential；2. without serious system
System property disease, no immune deficiency or autoimmune disease person；3. no active anaphylactia person；4. previously to skin type
Cosmetic is without allergies；5. whole body does not use hormone medicine and immunodepressant person in nearly January；6. it is clinical not participate in other
Experimenter；7. volunteer, which participates in and can press test requirements document, completes specified content person.
1.1.2 exclusion condition：1. gestation mends newborn phase women；2. based on outside work, Exposure to Sunlight person can not be avoided；3. test
Period causes Exposure to Sunlight enhancer because of a variety of causes (such as travel, spend a holiday)；4. trial employment period whole body application steroids, immune formulation class
Medicine person；5. trial employment period face applies anti-inflammatory drug person；6. the infull person of tested material or data is not used according to regulations.
1.1.3 number of subjects：54 people (meet cosmetics moistening effect evaluation guide and whitening class cosmetic industry are assessed
Subject's quantity (more than 30 people) of guide for method principle defined).
1.2 method
1.2.1 the preparation of given the test agent：In order to avoid sample in set-up procedure by microorganism pollution, it is direct with facial mask
The scissors of contact, packaging bag etc. sterilize before use, and the personnel for preparing sample wear gloves operation.
1.2.2 facial test position：Facial forehead, chin, left cheek, right cheek are as pilot region.
1.2.3 facial method of testing：White-skinned face function product (cosmetics, topical drug can not be used before face test within 2-3 days
Or health products for oral administration).Before experiment, subject needs unified cleaning skin of face, with dry face tissue wiped clean.Allow subject
Sit quietly at least 30min in standard compliant room, skin of face exposure, it is impossible to rub, keep loosening.
1.2.4 testing time-effectiveness：Periodicity efficacy assessment, 3 times a week, follow-on test 12 weeks.
1.2.5 evaluation：Facial mask trial effect is evaluated by the way of questionnaire, and wherein moisture retention is surveyed by skin moisture
Examination instrument is evaluated, and outward appearance and whitening highlight effect and pass through subject's sensory evaluation
The facial mask sense organ evaluating meter of table 3
1.3 experimental result
Sensory testing is carried out to 54 Eligible subjects, there are 4 people halfway because different reasons exit, it is final to obtain complete test
As a result 50 parts, test result is divided into typically, satisfied and very satisfied Three Estate, the number of each grade under each test item is entered
Row statistics, obtains corresponding test result, whole test result is as shown in the table：
The facial mask Analyses Methods for Sensory Evaluation Results table of 4 prescription of table 1
The facial mask Analyses Methods for Sensory Evaluation Results table of 5 prescription of table 2
The facial mask Analyses Methods for Sensory Evaluation Results table of 6 prescription of table 3
The facial mask Analyses Methods for Sensory Evaluation Results table of 7 prescription of table 4
3rd, the facial mask moisture retention test that skin moisture teller measures
2.1 laboratory apparatus
Bioelectrical impedance analysis (BIA) technology, digital skin tester
2.2 principle
Skin moisture content is determined by inside and outside two kinds of factors, keratoderma keep moisture content capacity variation compared with
Greatly, water content can be from 10% to 60% change, most important or skin perspiration respiratory and the mixing of skin reclaimed water
The composition of thing.External factor includes environment temperature, humidity, medicine and cosmetics etc., can determine and change the moisture content in skin
Content.Skin moisture content can influence the water of skin surface and the formation of grease hybrid films, and this layer of diaphragm declines to skin
It is always very important.Therefore the test skin moisture content of quantification and the variable quantity after relatively certain nursing stage are that have very much
.
2.3 experimental method
Strong effect product (cosmetics, topical drug or health products for oral administration) can not be used before face test within 2-3 days.Experiment
Before, subject needs unified cleaning skin of face, with dry face tissue wiped clean.Subject is allowed in standard compliant room
Sit quietly at least 30min, skin of face exposure, it is impossible to rub, keep loosening.With skin moisture teller measure skin forehead and
The moisture of cheek, reading simultaneously record tested preceding moisture of skin.
Remove, patted to absorption after face mask film 15min.Without using any facial products in 12 hours, exist respectively
10min, 30min, 60min, 12h, rear test, and record tested rear moisture of skin.
Using increasing value method (increasing value=tested rear moisture of skin-tested preceding moisture of skin) is averaging, obtain using production
The moisture increasing value of facial skin after product.
2.4 experimental result
The prescription 1 of table 8
The prescription 2 of table 9
The prescription 3 of table 10
The prescription 4 of table 11
4th, tyrosinase inhibitory activity is tested
Experimental method (with reference to " Wei Zhen holds Guangzhou Food Industry science and technology .Vol.20No.3, P10-11 ")：Take prescription 1,2,
3rd, 4, the 5 Essence 10ml prepared.With phosphate buffer (pH=6.8) sample dissolution, every kind of sample is each configured into concentration is
1mg/ml sample is to be measured.
2ml (blank group is with phosphate buffer replacement) is respectively taken to add tyrosinase (100U) in each test group, at 37 DEG C
10min is heated in Water Tank with Temp.-controlled, 0.003mol/L dopa reaction liquid 1ml is added, is sufficiently stirred, it is anti-in 37 DEG C (waters bath with thermostatic control)
After answering 2min, take out immediately, determine the absorbance at 475nm.
Inhibiting rate={ [(A-B)-(C-D)]/(A-B) } * 100%
A adds the absorbance that the mixed liquor of tyrosinase measures at 475nm for the product of not being loaded；B is not to be loaded product and do not add
The absorbance that the mixed liquor of tyrosinase measures at 475nm；C surveys for the mixed liquor of sample-adding product and tyrosinase at 475nm
The absorbance obtained；D does not add the absorbance that the mixed liquor of tyrosinase measures at 475nm for sample-adding product.
Inhibiting rate of the table 12 to tyrosinase
Test result indicates that:The solution of prescription 4 is best to the inhibition of tyrosinase, inhibiting rate 39%, hence it is evident that be better than
Other each groups, this also indicates that the whitening function of prescription 4 is better than other each groups.
Conclusion：
Although the herb extract total content contained in prescription 1~4 it can be seen from above-mentioned three kinds experiments is identical, so
And after four kinds of radix glycyrrhizae, green tea, olive leaf and giant knotweed herb extracts are applied in combination, whitening highlights notable with the effect such as moisturizing
Better than alone one of which extract (such as prescription 1) and two-by-two compatibility (such as prescription 2) and three kinds of extract compatibility (such as prescriptions
3), this is indicated that, after four kinds of herb extracts are applied in combination the present invention, synergistic function has been played, to human skin
Whitening highlights to be significantly improved with moisturizing activity, and four kinds of extracts are indispensable.
Claims (16)
- A kind of 1. skin whitening, moisturizing composition, it is characterised in that：It is the external application system being prepared with the raw material of following weight proportion Agent：5~50 parts of licorice, 5~50 parts of Olive leaf P.E, 5~50 parts of green-tea extract, Gentrin Knotweed P.E 1~10 Part；The preparation method of the extract is as follows：The preparation of licorice：Radix glycyrrhizae is weighed, adds water refluxing extraction, merges extract solution, is filtered, is concentrated, dries, produces radix glycyrrhizae Extract；The preparation of green-tea extract：Green tea is taken, is extracted using 70%v/v alcohol refluxs, after extract solution recovery ethanol, then uses HPD- 600 macroreticular resins carry out adsorption and purification, are eluted using 80%v/v ethanol, collect ethanol eluate, reclaim ethanol, concentrate, Dry, produce green-tea extract；The preparation of Olive leaf P.E：Olive leaf is taken, is extracted using 90%v/v alcohol refluxs, after extract solution recovery ethanol, is used AB-8 macroporous resin adsorptions purify, and make eluent with 70%v/v ethanol and then collect efflux, after reclaiming ethanol, using acetic acid The extraction of ethyl ester-water system, collects ethyl acetate layer, with silica gel post separation, with ethyl acetate：Ethanol=5:1 elution, collects elution Liquid, after recycling design, dry, produce Olive leaf P.E；The preparation of Gentrin Knotweed P.E：Giant knotweed is taken, is extracted using pH=2 60%v/v EtOH Sonicates, extract solution LS-303 macropores Polymeric adsorbent carries out adsorption and purification, makees eluent with 70%v/v ethanol and then collects efflux, after reclaiming ethanol, concentrates, does It is dry, produce Gentrin Knotweed P.E.
- 2. skin whitening, moisturizing composition according to claim 1, it is characterised in that：It is with the raw material system of following weight proportion The standby external preparation formed：12 parts of licorice, 12 parts of Olive leaf P.E, 10 parts of green-tea extract, 5 parts of Gentrin Knotweed P.E.
- 3. composition according to claim 1, it is characterised in that：In the licorice, general flavone content is not less than 10mg/g, total saponin content are not less than 40mg/g；In the Olive leaf P.E, hydroxytyrosol content is not less than 80mg/g；Institute State in green-tea extract, catechin content is not less than 400mg/g, and EGCG is not less than 130mg/ g；In the Gentrin Knotweed P.E, Resveratrol content is not less than 400mg/g.
- 4. composition according to claim 3, it is characterised in that：In the licorice, general flavone content is 17.8mg/g, total saponin content 55mg/g；In the Olive leaf P.E, hydroxytyrosol content 100mg/g；The green tea carries Take in thing, catechin content 500mg/g, EGCG 150mg/g；In the Gentrin Knotweed P.E, Resveratrol 500mg/g.
- A kind of 5. skin whitening, moisturizing composition, it is characterised in that：It is the external application system being prepared with the raw material of following weight proportion Agent：5~50 parts of licorice, 5~50 parts of Olive leaf P.E, 5~50 parts of green-tea extract, Gentrin Knotweed P.E 1~10 Part；In the licorice, general flavone content 17.8mg/g, total saponin content 55mg/g；The Olive leaf P.E In, hydroxytyrosol content 100mg/g；In the green-tea extract, catechin content 500mg/g, epi-nutgall acid catechin Gallate 150mg/g；In the Gentrin Knotweed P.E, resveratrol 500mg/g.
- 6. skin whitening, moisturizing composition according to claim 5, it is characterised in that：It is with the raw material system of following weight proportion The standby external preparation formed：12 parts of licorice, 12 parts of Olive leaf P.E, 10 parts of green-tea extract, 5 parts of Gentrin Knotweed P.E.
- 7. according to the composition described in claim 1-6 any one, it is characterised in that：The composition is with above-mentioned each extraction Thing is active component, the preparation for external application to skin being prepared plus the auxiliary material or complementary composition commonly used in pharmaceutically or cosmetically.
- 8. composition according to claim 7, it is characterised in that：The complementary composition is hyaluronic acid.
- 9. according to the composition described in claim 1-6 any one, it is characterised in that：The external preparation is face cream, breast Liquid, gel, toner, Essence or facial mask.
- A kind of 10. whitening moisturizing face masque, it is characterised in that：Per in 1000ml facial mask essences, contain following composition：The preparation method of the extract is as follows：The preparation of licorice：Radix glycyrrhizae is weighed, adds water refluxing extraction, merges extract solution, is filtered, is concentrated, dries, produces radix glycyrrhizae Extract；The preparation of green-tea extract：Green tea is taken, is extracted using 70%v/v alcohol refluxs, after extract solution recovery ethanol, then uses HPD- 600 macroreticular resins carry out adsorption and purification, are eluted using 80%v/v ethanol, collect ethanol eluate, reclaim ethanol, concentrate, Dry, produce green-tea extract；The preparation of Olive leaf P.E：Olive leaf is taken, is extracted using 90%v/v alcohol refluxs, after extract solution recovery ethanol, is used AB-8 macroporous resin adsorptions purify, and make eluent with 70%v/v ethanol and then collect efflux, after reclaiming ethanol, using acetic acid The extraction of ethyl ester-water system, collects ethyl acetate layer, with silica gel post separation, with ethyl acetate：Ethanol=5:1 elution, collects elution Liquid, after recycling design, dry, produce Olive leaf P.E；The preparation of Gentrin Knotweed P.E：Giant knotweed is taken, is extracted using pH=2 60%v/v EtOH Sonicates, extract solution LS-303 macropores Polymeric adsorbent carries out adsorption and purification, makees eluent with 70%v/v ethanol and then collects efflux, after reclaiming ethanol, concentrates, does It is dry, produce Gentrin Knotweed P.E.
- A kind of 11. whitening moisturizing face masque, it is characterised in that：Per in 1000ml facial mask essences, contain following composition：In the licorice, general flavone content 17.8mg/g, total saponin content 55mg/g；The Olive leaf P.E In, hydroxytyrosol content 100mg/g；In the green-tea extract, catechin content 500mg/g, epi-nutgall acid catechin Gallate 150mg/g；In the Gentrin Knotweed P.E, resveratrol 500mg/g.
- 12. the whitening moisturizing face masque according to claim 10 or 11, it is characterised in that：In every 1000ml facial mask essences, Contain following composition：
- 13. the facial mask according to claim 10 or 11, it is characterised in that：The preservative is Phenoxyethanol；The pH is adjusted Section agent is selected from sodium citrate.
- 14. the facial mask according to claim 10 or 11, it is characterised in that：Also containing little in per 1000ml facial mask essences In 1g essence.
- 15. according to the facial mask described in claim 10,11 or 14, it is characterised in that：Also contain in per 1000ml facial mask essences 0.002g essence.
- 16. the preparation method of Essence in facial mask described in claim 10~15 any one, it is characterised in that：It includes as follows Operating procedure：1. carbomer is dissolved with water；2. hydroxyethyl cellulose is dissolved with water, insoluble matter is filtered out, filtrate mixes with the carbomer aqueous solution, is sufficiently stirred；3. sequentially add butanediol, propane diols and stir；4. adding hyaluronic acid, stir, add pH adjusting agent, be sufficiently stirred；5. licorice is added, green-tea extract, Olive leaf P.E, Gentrin Knotweed P.E stirring；6. adding residual components, it is sufficiently stirred；7. the solution constant volume that will have been configured, sterilizing, are produced.
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| CN106389258A (en) * | 2016-11-04 | 2017-02-15 | 王少琼 | Moisture-preservation sunscreen skin whitening composition as well as preparation method and application thereof |
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| CN107595714A (en) * | 2017-10-31 | 2018-01-19 | 广东丸美生物技术股份有限公司 | A kind of Gentrin Knotweed P.E and preparation method thereof and the application in cosmetics |
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Effective date of registration: 20240307 Address after: Room 1304, No. 152 Huangbian North Road, Helong Street, Baiyun District, Guangzhou City, Guangdong Province, 510000 Patentee after: Guangzhou Wanqian vermicelli Cosmetics Co.,Ltd. Guo jiahuodiqu after: Zhong Guo Address before: 610041 Fifth Floor 501, B3 Floor, Tianfu Life Science and Technology Park, 88 South Road, Fengjiawan Industrial Park, Chengdu High-tech Zone, Sichuan Province Patentee before: CHENGDU SCISYN PHARMACEUTICAL CO.,LTD. Guo jiahuodiqu before: Zhong Guo |