CN106511218A - Emulsion capable of removing acne - Google Patents

Abstract

The invention discloses an emulsion which contains bletilla striata root extract and is capable of removing acne. The emulsion comprises natural plant components such as the bletilla striata root extract, radix scutellariae extract and mentha haplocalyx extract. The emulsion has the advantages that the three components are complementarily and scientifically compounded to achieve effects such as clearing away heat and toxic materials, regulating skin grease balance, inhibiting bacteria and diminishing inflammation, eliminating free radicals, nourishing the skin, supplementing skin collagen and increasing skin elasticity, and the emulsion is evident in acne removing effect and has effects of whitening and resisting oxidation; the emulsion contains the bletilla striata root extract capable of repairing skin functions, is capable of promoting the synthesizing of wound surface cell DNA, increasing cell proliferation ability, providing nutrition for cell proliferation and increasing skin collagen fibers and is helpful to the repairing of damaged skin caused by the acne.

Description

A kind of anti-acne emulsion

Technical field

The present invention relates to cosmetic field, and in particular to a kind of anti-acne emulsion.

Background technology

Acne is one of modal skin problem, is shown according to Epidemiological study, west 80% teenager and 50% adult has different degrees of acne, and almost 95% Chinese face length has " comedo ", and 55% people Long-term long pox.Acne is a kind of pilosebaceous infective inflammation.Follicular orifice is opened on sebaceous gland more, once follicular orifice resistance Plug, the work of the propionibacterium acness of hyper-proliferative in the stimulation of the fatty acid that excessive sebum metabolism is produced and enclosed environment With, make skin generate inflammatory reaction, the lipase that propionibacterium acness are produced decomposes sebum and generates free fatty, while chemotactic Inflammatory cell and medium, finally induce and increase inflammatory reaction.Therefore the performance of small pox is from gently to being hoary hair's blackhead, inflammation again Property pimple and pustule, cyst and tuberosity, and the rubescent and small pox suppurated is with the presence of bacterium infection.

Nutrition is rich in plant component, in some special places or some rare Special plants, often containing peculiar Active component.Such as inhibiting bacteria and diminishing inflammation active component, whitening skin and preserving moisture composition etc..With biochemistry, cytology, Dermatology it is continuous Development, people are also more and more to plant research, moreover, often produce safety problem in cosmetic industry in recent years, people for The favor degree of plant product also more and more higher, healthy to cosmetics, green, the natural demand of consumer, scientific research personnel are being planted The input of thing cosmetic field is also continued to increase, so, study plant extract and add it to, in cosmetics, make cosmetics With specific effect, it is a trend of whitening class cosmetics.

Chinese patent application CN 104434620A discloses a kind of acne-removing composition and preparation method thereof, including Ka Boshu Fat, hydroxyethyl cellulose, glycine betaine, Mentholum, salicylic acid, Propylene Glycol, the de- composition such as acyl chitin, the composition of the invention contain Some salicylic acid can dissolve the composition material between cutin, make horny layer come off, life-time service, and burden can be caused to skin, quick Sense skin, fat leakage property skin are not suitable for using salicylated product.

The products such as " anti-acne ", " except pox ", " anti-acne " are much declared on market, has medicament, the product of medicine adornment class, such as added anti- The materials such as raw element, glucocorticoid, metronidazole, can induce dysbacteriosiss, have certain infringement to skin, and life-time service can shadow Sound is healthy.

The content of the invention

It is an object of the invention to provide a kind of anti-acne emulsion, the vegetable composition with inhibiting bacteria and diminishing inflammation effect is added on In emulsion so that the natural safety of anti-acne emulsion, there is significant anti-acne skin effect.

A kind of anti-acne emulsion that the present invention is provided is comprising being made up of Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Scutellariae extract, Folium Menthae extract Vegetable composition, wherein the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Scutellaria baicalensis extract, the weight portion of Folium Menthae extract in the vegetable composition Than for (2-10)：(1-8)：(2-4).

Described Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Scutellaria baicalensis extract, the weight portion of Folium Menthae extract are：Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.2-1 Part, Scutellaria baicalensis extract 0.1-0.8 parts, Folium Menthae extract 0.2-0.4 parts.

The preparation method of the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract is as follows：

(1) take Pseudobulbus Bletillae (Rhizoma Bletillae) root, clean dry is ground into coarse grain, coarse grain water boiling and extraction 3 times, each 1.5- of decocting time 2h, merges filtrate twice, stands 2-4h, filters, and filtrate is standby；

(2) filtrate reduced in volume obtained by step (1) is obtained into thick medicinal extract, thick medicinal extract is spray-dried into (inlet temperature 170 DEG C, 60 DEG C of outlet temperature), dried extractum is ground into into the fine powder of 70 mesh sizes, the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract is obtained final product.

The preparation method of the Radix Scutellariae root extract is as follows：Radix Scutellariae is crushed to after 20-40 mesh, with ethanol percolate extraction, Percolate reclaims dilute after ethanol, uses resin column chromatography for separation, uses organic solvent eluting, collects organic solvent eluent, Solvent is reclaimed, Radix Scutellariae extract is obtained final product.

Preferably, the concentration of the ethanol is 50-85%.

Preferably, the resin is ion exchange resin.

Preferably, the organic solvent is ethyl acetate.

A kind of anti-acne emulsion, is composed of the following components in parts by weight：Vegetable composition 0.5-2.2 parts, allantoin 0.05- 0.2 part, glycerol 2-8 parts, 1,3- Propylene Glycol 3-6 parts, carbomer 0.1-0.2 parts, hyaluronate sodium 0.01-0.05 parts, Pyrusussuriensiss it is smooth Fructus Canarii albi oleate 1-2 parts, cetearyl glucoside 0.5-1 part, 16/18 alcohol 1-3 parts, olive oil 0.1-1 parts, Oleum Hippophae 1- 2 parts, potassium sorbate 0.3-0.5 parts, 1,2- hexanediol 0.1-0.5 parts, deionized water is to 100 parts.

A kind of described anti-acne emulsion includes following preparation process：

1) by Pyrusussuriensiss smooth Fructus Canarii albi oleate, cetearyl glucoside, 16/18 alcohol, olive oil, Oleum Hippophae input oil phase Pot, is heated to 70-85 DEG C, stirs to all components heat preservation for standby use after melting；

2) by glycerol, 1,3-PD, carbomer, hyaluronate sodium, deionized water input emulsifying pot, it is heated to 70-85 DEG C, stirring insulation 15-30 minutes；

3) by step 1) in oil phase suction step 2) emulsifying pot in, homogenizing (homogenizing stir speed (S.S.) be 3000rpm) 3～ Insulated and stirred (stir speed (S.S.) is 30rpm) 15-45 minutes after 15 minutes；

4) under 102-108MPa pressure, 81-82 DEG C of temperature conditionss, homogenizing 8-9 time is circulated by high pressure homogenizer, is controlled Homogenizer outlet temperature is less than 85 DEG C, obtains emulsion of the particle diameter in below 100nm；

5) by step 4) in emulsion be cooled to 40～45 DEG C, add above-mentioned vegetable composition, allantoin, potassium sorbate, 1,2- hexanediol, stir discharging.

Effect or feature of plant extract of the present invention is as follows：

Pseudobulbus Bletillae (Rhizoma Bletillae) root extract contains polysaccharide, bibenzyl and luxuriant and rich with fragrance class and its derivant, the biphenyl and double hydrogen phenanthrene class in extract Compound has inhibitory action to bacillus subtilis, staphylococcus aureuses, Candida albicans.Its gelling ingredient, can remarkably promote wound The synthesis of face superficial cell DNA, improves the multiplication capacity of cell, shortens wound healing time.Due to new capillary vessel quantity Increase, the nutrient of abundance both can be provided for cell propagation, the microcirculation of wound surface local can be improved again, be conducive to wound surface to heal Close；The increase of collagen fiber can improve the elasticity and toughness of newborn epithelium, and the propagation of newborn epithelial cell is conducive to wound surface Covered as early as possible, reduced infection probability.

Scutellaria baicalensis extract is cold in nature, bitter in the mouth, the Jing such as return lung, gallbladder, stomach, large intestine, with heat clearing and damp drying, let out fire clear away heart-fire, removing heat from blood live The effects such as blood.Recently as the further investigation to its active component baicalin and baicalin, Radix Scutellariae root extract is found especially It is that flavone compound has antibacterial, antiviral, antitumor, antipyretic-antalgic, antioxidation and scavenging activated oxygen and treatment painstaking effort Pipe disease etc. is acted on.

Folium Menthae extract contains substantial amounts of polyphenol, and Flavonoid substances are applied to local, have stimulation nerve, antipruritic effect；It is thin Lotus brain mainly contains various monoterpenes compounds, and pharmaceutical research shows which has antioxidation, antibacterial, radioprotective etc. biological living Property.Menthol also shows good Transdermal absorption effect, and effective ingredient preferably can be less readily available for absorption by the skin, and page has suppression skin Fat is secreted, and adjusts the effect of skin oil and fat balance.

Beneficial effects of the present invention：(1) vegetable composition Pseudobulbus Bletillae (Rhizoma Bletillae) root extract of the invention is monarch, and Scutellaria baicalensis extract is Minister, Folium Menthae extract are made for assistant, and three kinds of compositions are free by heat-clearing and toxic substances removing, regulation skin oil and fat balance, inhibiting bacteria and diminishing inflammation, removing The approach such as base, supplementary skin collagen and increase skin elasticity complement each other so that compositionss show significant anti-acne effect, together When, also have whitening, antioxidation concurrently；(2) anti-acne emulsion of the invention, property are gentle, compound glycerol, the hyalomitome of small molecule Sour sodium, deep water supplement water lock；1,2- hexanediol promotes the absorption of effective ingredient；Compounding olive oil, cleanable pore, exfoliation, Glycerin, prevents skin sunburn and skin allergy；Compounding Oleum Hippophae promotes Dermal microvessel circulation, while with stronger Film forming ability.By the coordination of component, the anti-acne emulsion of the present invention has excellent water lock moistening effect；(3) anti-acne of the invention Emulsion contains with the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract for repairing skin function, with the synthesis for promoting wound surface superficial cell DNA, improves cell Multiplication capacity and provides nutrient for cell propagation, increase collagen fibers of skin, contribute to damaging skin because what long pox caused Repair.

Description of the drawings

Figure one：Scavenging activity of the vegetable composition to DPPH.

Specific embodiment

Below in conjunction with specific embodiment, the present invention is further elaborated.

The following component title occurred in text is INCI (Internation Nomenclaure Cosmetic Ingredent, i.e. international cosmetic raw material name) institute to regulation title：It is cetearyl alcohol/cetearyl glucoside, sweet Oleostearin acid esters/PEG-100 stearates.

1～5 anti-acne emulsion formulations of the present invention of the embodiment of the present invention are shown in Table one

The preparation method of 1～5 anti-acne emulsion of embodiment, it is characterised in that comprise the steps：

1) by Pyrusussuriensiss smooth Fructus Canarii albi oleate, cetearyl glucoside, 16/18 alcohol, olive oil, Oleum Hippophae input oil phase Pot, is heated to 70-85 DEG C, stirs to all components heat preservation for standby use after melting；

2) by glycerol, 1,3-PD, carbomer, hyaluronate sodium, deionized water input emulsifying pot, it is heated to 70-85 DEG C, stirring insulation 15-30 minutes；

3) by step 1) in oil phase suction step 2) emulsifying pot in, homogenizing (homogenizing stir speed (S.S.) be 3000rpm) 3～ Insulated and stirred (stir speed (S.S.) is 30rpm) 15-45 minutes after 15 minutes；

4) under 102-108MPa pressure, 81-82 DEG C of temperature conditionss, homogenizing 8-9 time is circulated by high pressure homogenizer, is controlled Homogenizer outlet temperature is less than 85 DEG C, obtains emulsion of the particle diameter in below 100nm；

5) by step 4) in emulsion be cooled to 40～45 DEG C, add above-mentioned vegetable composition, allantoin, potassium sorbate, 1,2- hexanediol, stir discharging.

Comparative example 1

Difference with embodiment 1 is not add Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, and other preparation conditions and method are same as Example 1.

Comparative example 2

Difference with embodiment 1 is not add Scutellaria baicalensis extract, and other preparation conditions and method are same as Example 1.

Comparative example 3

Difference with embodiment 1 is not add Folium Menthae extract, and other preparation conditions and method are same as Example 1.

Comparative example 4

Difference with embodiment 1 is not add vegetable composition, and other preparation conditions and method are same as Example 1.

Comparative example 5

Difference with embodiment 1 is Pseudobulbus Bletillae (Rhizoma Bletillae) root extract content for 0.1 part, other preparation conditions and method and embodiment 1 It is identical.

Comparative example 6

Difference with embodiment 1 is Pseudobulbus Bletillae (Rhizoma Bletillae) root extract content for 1.1 parts, other preparation conditions and method and embodiment 1 It is identical.

Vegetable composition of the present invention removes DPPH capacity experimentals

Method and apparatus

Vegetable composition (is made by oneself)；95% ethanol (Chemical Reagent Co., Ltd., Sinopharm Group)；(Tokyo is melted into DPPH Co., Ltd., analyzes pure)；AB204-E electronic analytical balances (METTLE TOLEDO)；UV-1600 ultraviolet spectrophotometers (METTLE TOLEDO)。

DPPH is presented black purple in dehydrated alcohol and ethanol-water system, has maximum suction respectively under 517nm and 525nm Receive.Free radical scavenger can make purple gradually retreat, and go out the content of DPPH according to the change detection of absorbance and react freely Scavenging activity of the base scavenger to DPPH.

Precision weighs DPPH3.00mg, and 100ml is dissolved and be settled to 95% ethanol, and the solubility of DPPH is 20mg/L, is taken 4mlDPPH standard solution, is positioned in test tube, adds 1ml vegetable compositions, after placing 30min, in 517nm mensuration absorbances A.DPPH clearance rate is determined according to following equation；

The clearance rate of DPPH=[1- (Ai-Aj)/Ac] × 100%

Ai：The absorbance of extracting solution+4mlDPPH solution

Aj：The absorbance of extracting solution+4ml95% ethanol

Ac：The absorbance of 1ml95% ethanol+4mlDPPH solution

DPPH Scavenging activities are represented with clearance rate, clearance rate is higher to represent that Scavenging activity is stronger, by vegetable composition sample Product are diluted to 5%, 10%, 15%, 20%, 25% respectively with 95% ethanol, detect the ability that each concentration removes DPPH.As a result See Fig. 1, abscissa is vegetable composition concentration, and vertical coordinate is DPPH clearance rate.

As can be seen from Figure 1 vegetable composition of the present invention has Scavenging activity to DPPH, and removes as concentration increases Degree gradually increases, and after concentration reaches 15%, removing degree tends towards stability, and clearance rate reaches 83%.

Inhibition test to propionibacterium acness

The generation of acne is mainly blocked with hypersteatosiss, pilosebaceous duct, bacterium infection and inflammatory reaction etc. Factor is closely related.The androgen in descendant's body that adolesces is particularly the level of testosterone and raises rapidly, promotes sebaceous gland development And produce a large amount of sebums.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia to form cutin simultaneously Bolt is micropowder thorn.Multiple-microorganism especially propionibacterium acness amount reproduction in hair follicle, the lipase that propionibacterium acness are produced Decompose sebum and generate free fatty, while chemotactic inflammatory cell and medium, finally induce and increase inflammatory reaction.Thus may be used See, propionibacterium acness amount reproduction is a key factor for inducing comedo and causing comedo deterioration, therefore, it is right to study The inhibitory action of propionibacterium acness is to evaluate one of important method of sample anti-acne action effect.

(1) test specimen：Vegetable composition, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Scutellaria baicalensis extract, Herba Menthae in embodiment 1 is extracted The compositionss of thing, Scutellaria baicalensis extract and Folium Menthae extract, 5 groups of propionibacterium acness bacterial strain (are separated at patients with acne skin lesion To)；

(2) test method：

1. the culture of anaerobe, separation, identification：Isolated specimen inoculation will cultivate in THl0 at patients with acne skin lesion In base, airbag method is used, be placed in 37 DEG C of culture 72h in anaerobic jar, indicator is made with methylene blue, palladium grain is catalysis thorn.

2. the separation of anaerobe

Picking single bacterium colony, turns 2 pieces of flat boards, and one piece is placed in anaerobic jar, the lower 37 DEG C of pure cultures of anaerobic condition；Another piece with 37 DEG C of aerobic cultures；Result is observed after 48h.

3. the identification of anaerobe

Without bacterial growth under aerobic culture；

Occur the raised circle of homogeneous form, canescence, tiny, diameter about 1.O mm, edge on the flat board of Anaerobic culturel Bacterium colony is made microscopy by slightly neat bacterium colony, visible chromabacterium biolaceum under mirror.It is micro-bend in bar-shaped or shaft-like, can one end blunt circle, one end becomes Carefully, coloring is not deep, and cell is single, can arrange in pairs or arrange as shapes such as " people ", " v ".Again the test of Jing oxytolerants, catalase test, Indole test, biochemical series test for identification are propionibacterium acness.

4. anaerobism drug sensitive test

Inoculation：1 colony inoculation in the bacterium colony more than picking cultivated on LB plating mediums, the aerobic trainings of 370C Foster 24h, aerobic culture 24h propionibacterium acness are rinsed with physiological saline solution, and flushing liquor is put in sterile test tube；Using wheat Family name's turbidimetry need to be shaken before opacity tube 12 times than turbid, first than turbid to 3 × 108/mL, then with normal saline dilution to 106/mL It is standby.

LB plating mediums are inoculated with：The swab stick of sterilizing is dipped into bacterium solution, is squeezed on tube wall and is gone unnecessary bacterium solution, train in LB flat boards Even spread on foster base, and a circle is swept along plate edge ring, plate is covered, 2min is dried.Aseptic steel bowl (a diameter of 6mm) is light It is put on plating medium, fills it up with the vegetable composition obtained by embodiment 1, be put into 37 DEG C of aerobic culture 24h, finds nothing in plate Bacterial growth, is shown in have inhibition zone to be formed after continuing 37 DEG C of aerobic culture 24h.Antibacterial circle diameter is surveyed, 4 groups of antibacterial circle diameter values are taken Meansigma methodss.

Result of the test：To add the vegetable composition group obtained by embodiment 1 as experimental group, replaced with Pseudobulbus Bletillae (Rhizoma Bletillae) root extract real It is matched group 1 to apply 1 compositionss extract of example, replaces 1 compositionss extract of embodiment as matched group 2 with Scutellaria baicalensis extract, with thin It is matched group 3 that lotus extract replaces 1 compositionss extract of embodiment, replaces embodiment 1 with Scutellaria baicalensis extract and Folium Menthae extract Compositionss extract is matched group 4.Chinese medicine antibacterial susceptibility grade classification, with reference to corresponding antibiotic standard ".Inhibition zone diameter> 20mm is Gao Min, and 10～20mm is quick in being,<10mm is drug resistance, and concrete observation result is as shown in Table 2.

Table two

Efficacy assessments：The vegetable composition and Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Scutellariae of the present invention be can be seen that from above result of the test The compositionss of extract, Folium Menthae extract, Scutellaria baicalensis extract and Folium Menthae extract all have the effect for suppressing propionibacterium acness, And vegetable composition has high quick effect (antibacterial circle diameter to propionibacterium acness>20mm)；Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Scutellariae are extracted The compositionss of thing, Folium Menthae extract, Scutellaria baicalensis extract and Folium Menthae extract quick effect (inhibition zone in having to propionibacterium acness Diameter is between 10～20mm), it can thus be seen that Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Scutellaria baicalensis extract, Herba Menthae carry in vegetable composition of the present invention Take the effect that thing has Synergistic.

Efficacy validation

Detection results on probation are carried out to product prepared by embodiment 1-5 and comparative example 1-6, while declaring with a commercially available Essence with good acne-removing is matched group.Test object：Each experimental group is 20 women of homeliness type acne patient (25-50 year)；Test zone：Facial affected part；Use：Twice daily, persistently using 4 weeks；Test event：Anti-acne effect, water lock Moistening effect, repairing effect.Result on trial see the table below two.

It is substantially many by two visible embodiment of table, 1～5 pox effect, water lock moistening effect, the obvious number of repairing effect improvement In comparative example 1～6 and matched group, illustrate that the made essence of anti-apolexis composition of the present invention has significant pox effect, water lock moisturizing The effect of effect, repairing effect；4 anti-acne effect of comparative example is obviously improved 2 people, and water lock moisturizing is obviously improved 6 people, and wrinkle depth is repaiied Multiple effect is obviously improved 1 people, hence it is evident that less than other embodiment and comparative example, illustrates that vegetable composition is anti-acne emulsion master of the present invention Want effective ingredient；Comparative example 1 and comparative example 3 are respectively with the difference of embodiment 1 and are not added with Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Scutellariae extraction Thing, Folium Menthae extract, its skin elasticity, water are tender and wrinkle depth improves obvious number and is significantly lower than embodiment 1, comparative example 1～4 contrasts visible in phase anti-acne emulsion of the invention with embodiment 1, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Scutellaria baicalensis extract and Folium Menthae extract The Synergistic on anti-acne effect.

Represent that the more pale water of skin is tender using after anti-acne emulsion of the present invention using the patient of embodiment 1～5, people shows Obtain younger.

Above example only illustrates embodiment of the present invention, does not have any pro forma restriction to the present invention；Appoint What is engaged in professional and technical personnel, all has the ability to make some changes using the technology contents for disclosing or modifies, becomes equivalent The Equivalent embodiments of change, according to the technology of the present invention essence, carry out simply modification, equivalent variations and modification, belong to the present invention In the range of technical solution of the present invention.

Claims (9)

1. a kind of anti-acne emulsion, it is characterised in that the emulsion is comprising being extracted by Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Radix Scutellariae extract, Herba Menthae The vegetable composition of thing composition, wherein the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Scutellaria baicalensis extract, Folium Menthae extract in the vegetable composition Weight part ratio is (2-10)：(1-8)：(2-4).

2. a kind of anti-acne emulsion according to claim 1, it is characterised in that the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract, Scutellaria baicalensis extract, The weight portion of Folium Menthae extract is：

Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 0.2-1 parts

Scutellaria baicalensis extract 0.1-0.8 parts

Folium Menthae extract 0.2-0.4 point.

3. a kind of anti-acne emulsion according to claim 2, it is characterised in that the preparation method of the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract is such as Under：

(1) take Pseudobulbus Bletillae (Rhizoma Bletillae) root, clean dry is ground into coarse grain, coarse grain water boiling and extraction 3 times, each 1.5-2h of decocting time is closed And filtrate twice, 2-4h being stood, is filtered, filtrate is standby；

(2) filtrate reduced in volume obtained by step (1) is obtained into thick medicinal extract, thick medicinal extract is spray-dried (170 DEG C of inlet temperature, 60 DEG C of outlet temperature), dried extractum is ground into into the fine powder of 70 mesh sizes, the Pseudobulbus Bletillae (Rhizoma Bletillae) root extract is obtained final product.

4. a kind of anti-acne emulsion according to claim 2, it is characterised in that the preparation method of the Radix Scutellariae root extract is such as Under：Radix Scutellariae is crushed to after 20-40 mesh, with ethanol percolate extraction, dilute after percolate recovery ethanol, resin column chromatography is used Separate, use organic solvent eluting, collect organic solvent eluent, reclaim solvent, obtain final product Radix Scutellariae extract.

5. a kind of anti-acne emulsion according to claim 4, it is characterised in that the concentration of the ethanol is 50-85%.

6. a kind of anti-acne emulsion according to claim 4, it is characterised in that the resin is ion exchange resin.

7. a kind of anti-acne emulsion according to claim 4, it is characterised in that the organic solvent is ethyl acetate.

8. a kind of anti-acne emulsion according to any one of claim 1-7, it is characterised in that the anti-acne emulsion is by following heavy Amount part into being grouped into：

Vegetable composition 0.5-2.2 parts as claimed in claim 1

Allantoin 0.05-0.2 parts

Glycerol 2-8 parts

1,3- Propylene Glycol 3-6 parts

Carbomer 0.1-0.2 parts

Hyaluronate sodium 0.01-0.05 parts

The smooth Fructus Canarii albi oleate 1-2 parts of Pyrusussuriensiss

Cetearyl glucoside 0.5-1 part

16/18 alcohol 1-3 parts

Olive oil 0.1-1 parts

Oleum Hippophae 1-2 parts

Potassium sorbate 0.3-0.5 parts

1,2- hexanediol 0.1-0.5 parts

Deionized water is to 100 parts.

9. a kind of preparation method of anti-acne emulsion as claimed in claim 8, it is characterised in that comprise the steps：

1) by Pyrusussuriensiss smooth Fructus Canarii albi oleate, cetearyl glucoside, 16/18 alcohol, olive oil, Oleum Hippophae input oil phase pot, 70-85 DEG C is heated to, heat preservation for standby use after melting is stirred to all components；

2) by glycerol, 1,3-PD, carbomer, hyaluronate sodium, deionized water input emulsifying pot, 70-85 DEG C is heated to, is stirred Mix insulation 15-30 minutes；

3) by step 1) in oil phase suction step 2) emulsifying pot in, 3～15 points of homogenizing (homogenizing stir speed (S.S.) be 3000rpm) Insulated and stirred (stir speed (S.S.) is 30rpm) 15-45 minutes after clock；

4) under 102-108MPa pressure, 81-82 DEG C of temperature conditionss, homogenizing 8-9 time, control homogenizing are circulated by high pressure homogenizer Machine outlet temperature is less than 85 DEG C, obtains emulsion of the particle diameter in below 100nm；

5) by step 4) in emulsion be cooled to 40～45 DEG C, add above-mentioned vegetable composition, allantoin, potassium sorbate, 1,2- Hexanediol, stir discharging.