CN104661671B - 麸质相关病症 - Google Patents

麸质相关病症 Download PDF

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Publication number
CN104661671B
CN104661671B CN201380032073.2A CN201380032073A CN104661671B CN 104661671 B CN104661671 B CN 104661671B CN 201380032073 A CN201380032073 A CN 201380032073A CN 104661671 B CN104661671 B CN 104661671B
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cells
gluten
paracasei cba
cba
paracasei
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Chinese (zh)
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CN104661671A (zh
Inventor
弗兰切斯卡·罗曼·法萨诺
安德烈亚·路易吉·布代利
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Heinz Brand Co Ltd
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Heinz Brand Co ltd
Kraft Heinz Foods Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/335—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201380032073.2A 2012-06-18 2013-06-18 麸质相关病症 Active CN104661671B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261661105P 2012-06-18 2012-06-18
US61/661,105 2012-06-18
US201261725693P 2012-11-13 2012-11-13
US61/725,693 2012-11-13
PCT/US2013/046286 WO2013192163A1 (en) 2012-06-18 2013-06-18 Gluten-related disorders

Publications (2)

Publication Number Publication Date
CN104661671A CN104661671A (zh) 2015-05-27
CN104661671B true CN104661671B (zh) 2020-10-23

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CN201380032073.2A Active CN104661671B (zh) 2012-06-18 2013-06-18 麸质相关病症

Country Status (16)

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US (1) US10245300B2 (cg-RX-API-DMAC7.html)
EP (3) EP3901164B1 (cg-RX-API-DMAC7.html)
CN (1) CN104661671B (cg-RX-API-DMAC7.html)
AU (2) AU2013277316B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014031666B1 (cg-RX-API-DMAC7.html)
CA (1) CA2876963C (cg-RX-API-DMAC7.html)
DK (3) DK3351554T3 (cg-RX-API-DMAC7.html)
ES (3) ES3010649T3 (cg-RX-API-DMAC7.html)
IN (1) IN2014DN10798A (cg-RX-API-DMAC7.html)
MX (1) MX363899B (cg-RX-API-DMAC7.html)
NZ (1) NZ702936A (cg-RX-API-DMAC7.html)
PL (3) PL3351554T3 (cg-RX-API-DMAC7.html)
PT (3) PT3901164T (cg-RX-API-DMAC7.html)
RU (1) RU2654705C2 (cg-RX-API-DMAC7.html)
TR (1) TR201814973T4 (cg-RX-API-DMAC7.html)
WO (1) WO2013192163A1 (cg-RX-API-DMAC7.html)

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PT2734049T (pt) 2011-06-20 2018-07-24 Heinz Co Brands H J Llc Composições e métodos probióticos
BR112015028164B1 (pt) 2013-05-10 2022-02-08 H.J. Heinz Company Brands Llc Usos da bactéria probiótica, lactobacillus paracasei, para tratar uma infecção microbiana e para prevenir ou reduzir a gravidade de uma infecção microbiana
MX2019008292A (es) * 2017-01-12 2019-09-16 Probi Ab Composiciones probioticas y usos de las mismas.
CN113143973A (zh) * 2017-03-07 2021-07-23 景岳生物科技股份有限公司 抗骨质流失的副干酪乳杆菌菌株gmnl-653的组合物
KR102244007B1 (ko) * 2019-02-14 2021-04-23 주식회사 메디뉴트롤 글루텐 분해능을 가지는 락토바실러스 파라카제이 glu70 균주를 유효성분으로 함유하는 글리아딘으로 야기된 염증성 장 질환의 예방, 개선 또는 치료용 조성물
PL447563A1 (pl) * 2024-01-22 2025-07-28 Nordic Biotic Spółka Z Ograniczoną Odpowiedzialnością Szczep Lacticaseibacillus (L.) casei LC130, szczep Lacticaseibacillus (L.) paracasei LPC100, szczep Streptococcus (S.) salivarius ssp. thermophilus ST250, kompozycja obniżająca immunoreaktywność peptydów gliadyny oraz zastosowanie szczepów do wytwarzania kompozycji

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BR112015028164B1 (pt) 2013-05-10 2022-02-08 H.J. Heinz Company Brands Llc Usos da bactéria probiótica, lactobacillus paracasei, para tratar uma infecção microbiana e para prevenir ou reduzir a gravidade de uma infecção microbiana

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EP2861242A4 (en) 2016-01-20
CA2876963A1 (en) 2013-12-27
AU2013277316A1 (en) 2015-01-22
AU2013277316B2 (en) 2018-03-01
DK2861242T3 (en) 2018-10-29
WO2013192163A1 (en) 2013-12-27
ES3010649T3 (en) 2025-04-04
CA2876963C (en) 2021-07-06
AU2018203543B2 (en) 2020-02-27
CN104661671A (zh) 2015-05-27
ES2883552T3 (es) 2021-12-09
US10245300B2 (en) 2019-04-02
IN2014DN10798A (cg-RX-API-DMAC7.html) 2015-09-04
US20150174199A1 (en) 2015-06-25
RU2014150934A (ru) 2016-08-10
PT3351554T (pt) 2021-08-06
PL3351554T3 (pl) 2021-11-15
DK3351554T3 (da) 2021-08-30
BR112014031666B1 (pt) 2022-10-04
AU2018203543A1 (en) 2018-06-07
EP2861242B1 (en) 2018-08-08
TR201814973T4 (tr) 2018-11-21
EP3901164B1 (en) 2024-11-20
BR112014031666A2 (pt) 2017-10-31
PL3901164T3 (pl) 2025-04-14
EP3901164A1 (en) 2021-10-27
MX2014015314A (es) 2015-10-29
PT3901164T (pt) 2025-02-13
EP3351554A1 (en) 2018-07-25
EP3351554B1 (en) 2021-06-09
NZ702936A (en) 2017-06-30
PL2861242T3 (pl) 2019-04-30
MX363899B (es) 2019-04-05
ES2691087T3 (es) 2018-11-23
DK3901164T3 (da) 2025-02-03
RU2654705C2 (ru) 2018-05-22
PT2861242T (pt) 2018-11-07
EP2861242A1 (en) 2015-04-22

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