CN104645033A - Traditional Chinese medicine composition for treating staphylococcosis in chickens and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating staphylococcosis in chickens and preparation method thereof Download PDFInfo
- Publication number
- CN104645033A CN104645033A CN201310594038.1A CN201310594038A CN104645033A CN 104645033 A CN104645033 A CN 104645033A CN 201310594038 A CN201310594038 A CN 201310594038A CN 104645033 A CN104645033 A CN 104645033A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine composition
- parts
- staphylococcosis
- chicken
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine composition for treating staphylococcosis in chickens and a preparation method thereof. The traditional Chinese medicine composition comprises the following components, by weight, 10-20 parts of cordate houttuynia, 5-10 parts of viola philippica, 5-10 parts of rhizoma cyperi, 5-15 parts of magnolia cortex, 5-15 parts of bletilla striata, 5-15 parts of dandelion, 1-10 parts of Xiaoxian, 10-20 parts of cirsium japonicum dc and 5-10 parts of dried orange peel. The traditional Chinese medicine composition has antimicrobial and anti-inflammation effects, has little toxic and side effect, has no drug residue, is not easy to generate drug resistance, is easy to absorb, has high bioavailability, is convenient to use, meets requirements of safe veterinary drug and animal-derived food safety guarantee, and is an ideal traditional Chinese medicine composition for treating staphylococcosis in chickens.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition for the treatment of chicken staphylococcosis and preparation method thereof.
Background technology
Chicken staphylococcosis is acute septic or the chronic infectious disease of a kind of chicken caused by staphylococcus aureus or other staphylococcuses, its principal character is: acute generation septicemia, chronic type is suppurative arthritis, and synovitis or generation toe disease, also can show as multiple sick type.Along with intensive, the large-scale development of domestic poultry husbandry, the generation of chicken staphylococcosis is more and more serious, is endanger one of serious disease in poultry husbandry.
Chicken staphylococcosis produces enterotoxin contaminated food products on the one hand, alimentary toxicosis can occur under certain condition; On the other hand, due to modern age antibiotherapy extensive use and interpolation in animal feed, make originally to only have the staphylococcus of facultative etiologic agent humans and animals of being everlasting to cause disease, cause great economic loss to resident living.
Chinese herbal and crude drugs preparations, as natural drug, has the advantage of its uniqueness, can promote growth of animals or poultry, improve its fertility performance, side effect is little, not easily develops immunity to drugs, easy absorption and noresidue, therefore, Chinese herbal and crude drugs preparations is more and more subject to people and likes in the use procedure of society veterinary drug.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of chicken staphylococcosis, the present invention has effect that is antibacterial, antiinflammatory, and toxic and side effects is little, drug residue free, not easily produces drug resistance, easily absorbs, and bioavailability is high, easy to use.
Another object of the present invention is to provide a kind of preparation method for the treatment of the Chinese medicine composition of chicken staphylococcosis.
The present invention is achieved by the following technical solutions:
Treat a Chinese medicine composition for chicken staphylococcosis, component and the ratio of weight and number thereof of its Chinese medicine composition are respectively:
Treat a preparation method for the Chinese medicine composition of chicken staphylococcosis, the step of its preparation method is as follows:
(1) take Herba Houttuyniae, Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, Radix Cirsii Japonici and tangerine peel powder respectively according to weight proportion and be broken into powder, and respectively all by 80 mesh sieves;
(2) Herba Houttuyniae after sieving in step (1), Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, Radix Cirsii Japonici and Pericarpium Citri Reticulatae are put in blending tank, abundant mix homogeneously, the Chinese medicine composition finished product of the chicken staphylococcosis that namely obtains medical treatment.
Advantage of the present invention and beneficial effect are:
The Herba Houttuyniae contained in the Chinese medicine composition of 1, this treatment chicken staphylococcosis, Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, the Chinese medicinal ingredients such as Radix Cirsii Japonici and Pericarpium Citri Reticulatae, to the chicken staphylococcosis that staphylococcus aureus causes, there is good preventive and therapeutic effect, antibacterial action successful.
2, the Chinese medicine composition has a broad antifungal spectrum of this treatment chicken staphylococcosis, steady quality, does not affect by temperature and acid-base value, easy to use, easily absorbs, respond well, can reach blood peak concentration of drug within a short period of time with extremely low concentration.
3, the present invention has effect that is antibacterial, antiinflammatory, toxic and side effects is little, drug residue free, not easily produce drug resistance, easy absorption, bioavailability is high, easy to use, meeting safe veterinary drug, ensure the requirement of animal-derived food safety, is a kind of Chinese medicine composition of ideal treatment chicken staphylococcosis.
Detailed description of the invention
The present invention is described in further detail by following examples.It should be noted that: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Herba Houttuyniae involved in the present invention, Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, Radix Cirsii Japonici and Pericarpium Citri Reticulatae all commercially can be bought and obtain.
Embodiment 1
Treat a Chinese medicine composition for chicken staphylococcosis, component and the weight thereof of its Chinese medicine composition are respectively: Herba Houttuyniae 18g; Herba Violae 9g; Rhizoma Cyperi 8g; Cortex Magnoliae Officinalis 10g; Pseudobulbus Bletillae (Rhizoma Bletillae) 9g; Herba Taraxaci 9g; Little fresh 6g; Radix Cirsii Japonici 15g; Pericarpium Citri Reticulatae 8g.
A preparation method for the Chinese medicine composition for the treatment of chicken staphylococcosis, the step of its preparation method is as follows:
(1) take Herba Houttuyniae, Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, Radix Cirsii Japonici and tangerine peel powder respectively according to weight proportion and be broken into powder, and respectively all by 80 mesh sieves;
(2) Herba Houttuyniae after sieving in step (1), Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, Radix Cirsii Japonici and Pericarpium Citri Reticulatae are put in blending tank, abundant mix homogeneously, the Chinese medicine composition finished product of the chicken staphylococcosis that namely obtains medical treatment.
Embodiment 2
Treat a Chinese medicine composition for chicken staphylococcosis, component and the weight thereof of its Chinese medicine composition are respectively: Herba Houttuyniae 20g; Herba Violae 10g; Rhizoma Cyperi 10g; Cortex Magnoliae Officinalis 15g; Pseudobulbus Bletillae (Rhizoma Bletillae) 15g; Herba Taraxaci 15g; Little fresh 10g; Radix Cirsii Japonici 20g; Pericarpium Citri Reticulatae 10g.
The step of its preparation method is with embodiment 1.
Embodiment 3
Treat a Chinese medicine composition for chicken staphylococcosis, component and the weight thereof of its Chinese medicine composition are respectively: Herba Houttuyniae 10g; Herba Violae 5g; Rhizoma Cyperi 5g; Cortex Magnoliae Officinalis 5g; Pseudobulbus Bletillae (Rhizoma Bletillae) 5g; Herba Taraxaci 5g; Little fresh 1g; Radix Cirsii Japonici 10g; Pericarpium Citri Reticulatae 5g.
The step of its preparation method is with embodiment 1.
Embodiment 4
Treat a Chinese medicine composition for chicken staphylococcosis, component and the weight thereof of its Chinese medicine composition are respectively: Herba Houttuyniae 16g; Herba Violae 8g; Rhizoma Cyperi 8g; Cortex Magnoliae Officinalis 12g; Pseudobulbus Bletillae (Rhizoma Bletillae) 12g; Herba Taraxaci 12g; Little fresh 5g; Radix Cirsii Japonici 15g; Pericarpium Citri Reticulatae 10g.
The step of its preparation method is with embodiment 1.
Clinical practice
In order to verify the clinical therapeutic efficacy of the present invention to chicken staphylococcosis, we have carried out the clinical trial of the present invention to chicken staphylococcosis in the cultivation factory of certain infected chicken staphylococcosis of Dezhou City Shandong Province.The present invention is divided into basic, normal, high three dosage to carry out grouping administration to animal by test, compares, thus evaluate therapeutic effect of the present invention and optimum amount with the therapeutic effect of the conventional treatment drug of chicken staphylococcosis.
1, materials and methods
1.1 experimental animal
There is the chicken house of chicken staphylococcosis in Dezhou City Shandong Province, prevalence is up to more than 70%.
1.2 trial drug
The present invention is prepared by our company.
Amoxicillin: 100g/ bag, Zhengzhou Bary Animal Pharmaceutical Co., Ltd., product batch number * * * * * *
1.3 test method
The case of chicken staphylococcosis is made a definite diagnosis primarily of clinical symptoms and methods such as cuing open inspection change, then sick chicken random packet is treated by testing crew.
The diagnostic criteria of 1.4 chicken staphylococcosis
Clinical symptoms:
Acute sepsis type: sick chicken performance spirit is depressed, stay vertical or squat, necking down is hung down wing, drowsiness, loss of appetite, feather pine disorderly, local has and comes off, and has mulberry blood sample exudate after ulceration, and inside the sick Chicken Wings of part, the hemorrhagic focus that differs in size and inflammatory necrosis appear in the area skin such as the apex of the wing, tail, head and neck, the back of the body and lower limb, local desiccation forms a scab, and 2-3d is dead.Arthritis type: the multiple chicken being born in 4-12 age in week, with toe and sole of the foot joint common, in aubergine or atropurpureus, some ulcerations tie black purple crust, some appearance toe tumors, sole enlargement, some toes purple darkly that necroses is drier and more astringent, and sick chicken performance is walked lamely, and lies prostrate more, become thin because searching for food difficulty, decline and death.Omphalitis type: Embryo Gallus domesticus or newly go out the chickling annulus umbilicalis dysraphism of shell, namely omphalitis occurs after infecting staphylococcus, show as abdominal part and expand, umbilical opening enlargement inflammation, touch is hardened, and local is in yellowish red color or atropurpureus.Ophthalmia type: the upper and lower eyelid swelled of sick chicken, has purulent secretion to stick, eye conjunctiva is red and swollen, and the many secretions in canthus, even has blood, granuloma, course of disease elder enophthalmos, blind, and under some sockets of the eye, hole is swollen prominent.
Cut open inspection change:
Acute sepsis type: sick pigeon chest subcutaneous abdomen is congested, haemolysis, in diffusivity aubergine or dark red, there is a large amount of glue peptone sample yellowish red color edematous fluid, liver enlargement, changes in pale purple flower grain pattern, has the necrosis region that quantity does not wait, spleen enlargement is aubergine, the downright bad point of adularescent, pericardial effusion, heart hat is fatty and adventitia is sometimes hemorrhage.Arthritis type: have serosity or purulence thing in joint capsule, the later stage is caseous substance, periarticular connective tissue proliferation or structural deformities, and omphalitis type: umbilical part is blue, has dark red solution, and become purulence cheesy thing when the course of disease is long, absorption of yolk at its is bad.
1.5 experimental animal groupings and process
In chicken house, choose the Growing Chicken with chicken staphylococcosis clinical symptoms, and be divided into 5 groups at random, often group is no less than 300.
Testing 1 group is matched group, does not process;
Testing 2 groups is low dose group of the present invention, 1/2 times amount administration of clinical recommended dose (per kilogram of body weight 1g), spice, successive administration 3 days.
Testing 3 groups is dosage group in the present invention, clinical recommended dose (per kilogram of body weight 2g) administration, spice, successive administration 3 days.
Testing 4 groups is high dose group of the present invention, 2 times amount administrations of clinical recommended dose (per kilogram of body weight 4g), spice, successive administration 3 days.
Testing 5 groups is amoxicillin, uses to specifications: mixed drink, is watered the amount administration of 200kg, successive administration 3 days by 100g.
1.6 therapeutic effect decision methods
Clinical symptom disappearance, cuts open inspection without obvious pathological change.
Cure rate:
Medication postoperative infection chicken clinical symptom disappearance, appetite, spirit, wound etc. are recovered all to be judged as normally curing.The ratio calculating cure rate that this group tests chicken is accounted for according to curing number of elements.
Effective percentage:
The clinical symptom relief such as waste absolutely, the lassitude of sick chicken food, incrustation after medication, searches for food, spirit and traumatic event starts to take a turn for the better, but do not return to all being judged to effectively of premorbid state.The ratio accounting for this group test chicken number of elements according to effective number of elements calculates effective percentage.
Inefficiency:
After medication, the symptom such as waste absolutely, the lassitude of sick chicken food, incrustation is not still felt any better and is even worsened died, and it is invalid to be all judged as.The ratio accounting for this group test number of elements according to invalid number of elements calculates inefficiency.
1.7 statistical analysis
The percents such as therapeutic effect cure rate, effective percentage represent.Comparison in difference between group adopts X 2 test to analyze.P<0.05 and P<0.01 represents significant difference and extremely remarkable respectively.
2 result of the tests
To the chicken group of natural infection chicken staphylococcosis, give the Chinese medicine composition of the present invention of various dose respectively, after spice, by comparing with matched group, the clinical symptoms of morbidity chicken group obviously alleviates, and body weight rises appreciably.Therapeutic effect and the average Gain weight of middle dosage group all reach desirable requirement; Amoxicillin treatment of control group effect is ideal, but feed conversion rate is obviously not as the present invention.The results are shown in Table 1.
Table 1 observation of curative effect
3 interpretations of result
From clinical symptoms, cut open inspection change, average weight gain situation, cure rate four aspects analyze, the therapeutic effect of middle dosage group and high dose group apparently higher than other treatment group, wherein with middle dosage group to chicken staphylococcosis therapeutic effect the best.Amoxicillin matched group has certain therapeutic effect, but comparatively the present invention is poor to treat rear chicken average weight gain, and economic loss is larger.
4 conclusions
The present invention, by the administration of per kilogram of body weight 2g spice, treats the sick chicken suffering from chicken staphylococcosis for three days on end, remarkable to the chicken staphylococcosis caused by staphylococcus aureus, septicemia, omphalitis, bacterial endocarditis, arthritis and dermatitis effects.
Claims (2)
1. treat a Chinese medicine composition for chicken staphylococcosis, it is characterized in that: component and the ratio of weight and number thereof of this Chinese medicine composition are respectively:
2. a preparation method for the Chinese medicine composition for the treatment of chicken staphylococcosis as claimed in claim 1, is characterized in that: the step of this preparation method is as follows:
(1) take Herba Houttuyniae, Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, Radix Cirsii Japonici and tangerine peel powder respectively according to weight proportion and be broken into powder, and respectively all by 80 mesh sieves;
(2) Herba Houttuyniae after sieving in step (1), Herba Violae, Rhizoma Cyperi, Cortex Magnoliae Officinalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, little fresh, Radix Cirsii Japonici and Pericarpium Citri Reticulatae are put in blending tank, abundant mix homogeneously, the Chinese medicine composition finished product of the chicken staphylococcosis that namely obtains medical treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310594038.1A CN104645033A (en) | 2013-11-21 | 2013-11-21 | Traditional Chinese medicine composition for treating staphylococcosis in chickens and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310594038.1A CN104645033A (en) | 2013-11-21 | 2013-11-21 | Traditional Chinese medicine composition for treating staphylococcosis in chickens and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104645033A true CN104645033A (en) | 2015-05-27 |
Family
ID=53237003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310594038.1A Pending CN104645033A (en) | 2013-11-21 | 2013-11-21 | Traditional Chinese medicine composition for treating staphylococcosis in chickens and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104645033A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106563053A (en) * | 2015-10-13 | 2017-04-19 | 黄旺 | Drug for treating chicken staphylococcosis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579452A (en) * | 2008-05-13 | 2009-11-18 | 天津生机集团股份有限公司 | Traditional Chinese medicine composition for preventing and treating avian staphylocosis and preparation method thereof |
| CN102657772A (en) * | 2012-05-22 | 2012-09-12 | 山东新希望六和集团有限公司 | Decoction for treating avian staphylocosis, feed and preparation method |
| CN102940722A (en) * | 2012-12-03 | 2013-02-27 | 北京大北农动物保健科技有限责任公司 | Chinese medicinal composition for treating bacterial diseases of animals and preparation method thereof |
-
2013
- 2013-11-21 CN CN201310594038.1A patent/CN104645033A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579452A (en) * | 2008-05-13 | 2009-11-18 | 天津生机集团股份有限公司 | Traditional Chinese medicine composition for preventing and treating avian staphylocosis and preparation method thereof |
| CN102657772A (en) * | 2012-05-22 | 2012-09-12 | 山东新希望六和集团有限公司 | Decoction for treating avian staphylocosis, feed and preparation method |
| CN102940722A (en) * | 2012-12-03 | 2013-02-27 | 北京大北农动物保健科技有限责任公司 | Chinese medicinal composition for treating bacterial diseases of animals and preparation method thereof |
Non-Patent Citations (6)
| Title |
|---|
| 孙卫东: "《土法良方治鸡病》", 31 January 2010, 北京：化学工业出版社 * |
| 张庆茹等: "中草药防治鸡传染病研究进展", 《畜禽业》 * |
| 张贵林: "《禽病中草药防治技术》", 31 August 1998, 金盾出版社 * |
| 谭凤辉: "鸡葡萄球菌病应该怎样治疗?", 《吉林畜牧兽医》 * |
| 陈燕丽等: ""中草药抗金黄色葡萄球菌的研究现状"", 《中兽医医药杂志》 * |
| 黎细月等: "《兽药营销人才必读》", 30 November 2005, 中国农业科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106563053A (en) * | 2015-10-13 | 2017-04-19 | 黄旺 | Drug for treating chicken staphylococcosis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1879745A (en) | A veterinary Chinese medicinal powder for treating avian viral disease | |
| CN108853217A (en) | A kind of pharmaceutical composition and its application for treating chicken Mycoplasma synoviae | |
| CN105663546B (en) | Traditional Chinese medicine composition for treating proventriculitis of chicken | |
| CN103860715A (en) | Compound traditional Chinese medicine extract for preventing poultry coccidiosis and application of extract | |
| CN104523943A (en) | Compound fermentation type traditional Chinese medicine for preventing and treating multiple seasonal febrile diseases of livestock and poultry | |
| CN104644757A (en) | Traditional Chinese medicine oral liquid for treating avian influenza and preparation method thereof | |
| CN101259160B (en) | Compound preparations for treating birdsvirosis and preparation thereof | |
| CN101194995B (en) | Proprietary Chinese medicine for treating animal virus, bacterium and mix infection | |
| CN104645033A (en) | Traditional Chinese medicine composition for treating staphylococcosis in chickens and preparation method thereof | |
| CN109999117A (en) | Prevent and treat enteritis, bacillary dysentery, dysentery, intractable diarrhea Chinese medicine composition | |
| CN106214862B (en) | A kind of Traditional Chinese veterinary medicine oral solution and preparation method thereof preventing and treating the atypical newcastle disease of chicken | |
| CN104840591B (en) | A kind of Chinese medicine composition for having effects that to prevent ewcastle disease | |
| CN105641368A (en) | Traditional Chinese medicinal composition for treating avian infectious laryngotracheitis and preparation method of traditional Chinese medicinal composition | |
| CN103550314A (en) | Veterinary medicine for treating colibacillosis and white diarrhea | |
| CN103652490A (en) | Pig feed for treating blue-eared pig disease and preparation method thereof | |
| CN102885927A (en) | Traditional Chinese medicine composition for treating pullorum disease and preparation method thereof | |
| CN112546172A (en) | Chinese and western medicine composition for treating salpingitis and preparation method thereof | |
| CN105012684A (en) | Traditional Chinese medicine composition for treating staphylococcocci of poultry | |
| CN104222529A (en) | Feed for preventing porcine reproductive and respiratory syndrome | |
| CN104644742A (en) | Traditional Chinese medicine composition for treating infectious rhinitis of chicken and preparation method thereof | |
| CN105560769A (en) | Traditional Chinese medicine decocted fluid for treatment of chicken infectious bursal disease and preparation method thereof | |
| CN105770307B (en) | Traditional Chinese medicine composition for preventing and treating ascites syndrome of poultry, feed and application thereof | |
| CN102657772B (en) | Decoction for treating avian staphylocosis, feed and preparation method | |
| CN103861007A (en) | Chinese herbal medicine compound preparation for treating diarrhea of chicken | |
| CN116474014B (en) | Traditional Chinese medicine composition for treating chicken histomonas and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150527 |