CN105012684A - Traditional Chinese medicine composition for treating staphylococcocci of poultry - Google Patents
Traditional Chinese medicine composition for treating staphylococcocci of poultry Download PDFInfo
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Abstract
The invention belongs to the field of veterinary medicines and particularly relates to a traditional Chinese medicine composition for treating staphylococcocci of poultry. The traditional Chinese medicine composition is prepared by, by weight, 52-65 parts of heartleaf houttuynia herb, 55-65 parts of discolor cinquefoil herb, 50-65 parts of peony bark, 20-30 parts of hokker winghead herb, 50-60 parts of Chinese ligusticum rhizome, 50-65 parts of viscum angulatum heyne, 45-55 parts of dandelion, 38-50 parts of periostracum cicada, 40-55 parts of rhizoma acori tatarinowii, 40-55 parts of lotus rhizome nodes, 35-45 parts of dianthus superbus, 40-55 parts of Chinese violet herb, 16-25 parts of omphalia, 31-42 parts of cortex ailanthi, 25-35 parts of human placenta, 20-35 parts of sealwort, 40-55 parts of wild chrysanthemum flower, 20-35 parts of lumbricus, 20-30 parts of concha haliotidis and 20-35 parts of dahurian patrinia herb. The traditional Chinese medicine composition has good preventing and treating effects on the staphylococcocci of the poultry.
Description
Technical field
The invention belongs to field of veterinary, be specifically related to a kind of Chinese medicine composition for the treatment of poultry staphylococcosis.
Background technology
Chicken staphylococcosis is the acute or chronic infectious disease caused by infection of staphylococcus aureus, and acute person is septic, and mortality rate is up to more than 90%, general dead in 1 ~ 2 day, chronic person shows as the different disease types such as arthritis, dermatitis, ophthalmia, and mortality rate is lower, and generally about 10%.But chronic person is also easily converted into acute process, very fast dead, the especially growing chickens susceptible disease of 30 ~ 90 ages in days.Primary disease great majority by trauma infection contamination, as cage net iron wire scratch, peck wound, disconnected beak or immunity thorn kind time infection.In addition, 7 ~ August is onset peak period.It is worth mentioning that, the staphy lococcus infection of chronic dermatitis type, propagate very fast in summer, the loss caused is very large, and the control therefore for primary disease must draw attention.
The formidable enemy of current cultivation industry Blight control is exactly bacterial resistance, along with cultivating the antibiotic a large amount of use of industry in recent years, especially staphylococcus is very serious to antibiotic drug resistance, Luo Xiangwen, Tang little Yan are finding the resistance monitoring assays of staphylococcus aureus at 2007-2009, staphylococcus aureus reaches 80% for the resistant rate of penicillin, erythromycin, gentamycin, tetracycline etc., belongs to the degree of especially severe.
Summary of the invention
For overcoming above-mentioned defect, the object of the invention is to provide a kind of Chinese medicine composition for the treatment of poultry staphylococcosis, overcomes antibiotic drug resistance, does not have drug residue, does not pollute Fowl meat egg, and prevention and therapy is effective, have no side effect, cheap.
For achieving the above object, the present invention adopts following technical scheme:
Treat a Chinese medicine composition for poultry staphylococcosis, be made up of the raw material of following parts by weight:
Herba Houttuyniae 52-65 part, Herba Potentillae Discoloris 55-65 part, Cortex Moutan 50-65 part, Herba pterocephali 20-30 part, Rhizoma Ligustici 50-60 part, ebonyshoot mistletoe branchlet and leaf 50-65 part, Herba Taraxaci 45-55 part, Periostracum Cicadae 38-50 part, Folium Acori graminei 40-55 part, Nodus Nelumbinis Rhizomatis 40-55 part, Herba Dianthi 35-45 part, Herba Violae 40-55 part, Omphalia 16-25 part, Cortex Ailanthi 31-42 part, Placenta Hominis 25-35 part, Rhizoma Polygonati 20-35 part, Flos Chrysanthemi Indici 40-55 part, Pheretima 20-35 part, Concha Haliotidis 20-30 part, Herba Patriniae 20-35 part.
According to the Chinese medicine composition of above-mentioned treatment poultry staphylococcosis, be made up of the raw material of following parts by weight:
Herba Houttuyniae 60 parts, Herba Potentillae Discoloris 60 parts, Cortex Moutan 60 parts, Herba pterocephali 25 parts, Rhizoma Ligustici 60 parts, ebonyshoot mistletoe branchlet and leaf 60 parts, Herba Taraxaci 50 parts, Periostracum Cicadae 40 parts, Folium Acori graminei 50 parts, Nodus Nelumbinis Rhizomatis 50 parts, Herba Dianthi 40 parts, Herba Violae 50 parts, Omphalia 20 parts, Cortex Ailanthi 40 parts, Placenta Hominis 30 parts, Rhizoma Polygonati 30 parts, Flos Chrysanthemi Indici 50 parts, Pheretima 30 parts, Concha Haliotidis 25 parts, Herba Patriniae 30 parts.
According to the Chinese medicine composition of above-mentioned treatment poultry staphylococcosis, preparation method comprises the following steps: by each crude drug of above-mentioned parts by weight, dries, pulverizes 40 ~ 80 orders, mix homogeneously, and to obtain final product.
The feeding method of Chinese medicine composition of the present invention: be mixed in feedstuff in one day of fowl by the ratio of feed relative 3%-20%, mix thoroughly, take 3-7 days continuously.
the pharmacological action of the various crude drug of the present invention:
Herba Houttuyniae: pungent, is slightly cold, and returns lung meridian, heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome, and for lung abscess, intestinal is yellow, dysentery, acute mastitis, drenches worm.
Herba Potentillae Discoloris: sweet, micro-hardship, flat, heat clearing away, removing toxic substances, hemostasis, detumescence, controls dysentery, malaria, lung abscess, hemoptysis, spits blood, hematochezia, metrorrhagia, carbuncle, skin ulcer tinea, scrofula tuberculosis.
Cortex Moutan, bitter, pungent, be slightly cold, GUIXIN, liver, kidney channel, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, for maculae caused by violent heat pathogen, hematemesis and epistaxis, has blood in stool, and hematuria is fallen and flutterred the pain of injury, carbuncle sore tumefacting virus.
Herba pterocephali, bitter, cold, clearing away heat and expelling pathogen in the exterior, pure and fresh removing heat from blood.For the fever that cold, fever and various epidemic febrile disease cause, dysphoria with smothery sensation in the heart, hemoptysis, spit blood, hematuria, has blood in stool.
Rhizoma Ligustici, pungent, temperature.Return urinary bladder channel, dispel the wind, cold expelling, dehumidifying, pain relieving, for anemofrigid cold, top, top pain, rheumatism podomere arthralgia pain.
Ebonyshoot mistletoe branchlet and leaf, pungent, micro-puckery, warm, dehumidify, dispel the wind, control pneumonopathy and spit blood, breast ulcer, stomachache, treating rheumatic arthritis, waist and leg ache, hypertension, fetal movement, breast is few.
Herba Taraxaci, bitter, sweet, cold, return liver, stomach warp, heat-clearing and toxic substances removing. dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome, for treating pyogenic infections from tumour or sore, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, damp and hot yellow cellulitis, the puckery pain of pyretic stranguria.
Periostracum Cicadae, sweet, cold.Return lung, Liver Channel, loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Folium Acori graminei, pungent, temperature enters the heart, lung two warp, detoxification sore treatment, parasite killing.Control furuncle, leprosy, impetigo.
Nodus Nelumbinis Rhizomatis, dry and astringent, flat, hemostasis, dissipating blood stasis.Control hemoptysis, spit blood, epistaxis, hematuria, has blood in stool, dysentery, metrorrhagia.
Herba Dianthi: bitter, cold.GUIXIN, small intestine meridian, inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow.
Herba Violae: bitter, acrid, cold.GUIXIN, Liver Channel.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling, for the yellow furunculosis of skin ulcer, conjunctival congestion and swelling pain, venom.
Omphalia: bitter, cold, enter stomach, large intestine channel, removing food stagnancy, parasite killing, control abdominal pain due to worm stagnation, infantile malnutrition, acute infantile convulsion.
Cortex Ailanthi: bitter, puckery, cold, return large intestine, stomach, Liver Channel, heat clearing and damp drying, astringent therapy leukorrhagia stopping, antidiarrheal, hemostasis, for leucorrhea with red and white discharge, damp-heat dysentery, chronic diarrhea chronic dysentery, has blood in stool, metrorrhagia.
Placenta Hominis: Gan Xian, temperature, QI invigorating, nourishes blood, benefit essence, deficient, and weakness and emaciation, hemoptysis is panted, consumptive fever hectic fever due to YIN-deficiency, the diseases such as seminal emission.
Rhizoma Polygonati: sweet is flat; Return lung, spleen, kidney channel, nourishing kidney profit spleen, invigorating the spleen and replenishing QI, deficiency of YIN chronic cough, xeropulmonary cough, insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission, tinnitus order is dark, early whitening of beard and hair; Body weakness with emaciation is thin, the insane tinea disease of wind.
Flos Chrysanthemi Indici: bitter, pungent, is slightly cold.Return liver, heart channel, heat-clearing and toxic substances removing, suppressing the hyperactive liver improving eyesight.For sore carbuncle, conjunctival congestion and swelling pain, has a headache dizzy.
Pheretima: salty in the mouth, cold in nature, be heat clearing away, spasmolytic, Zhichuan, diuresis, fanatical hot-tempered for height, convulsion with spasms, headache conjunctival congestion, expectorant heat of panting, apoplexy, the diseases such as hemiplegia.
Concha Haliotidis: salty, cold, returns Liver Channel, suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving, dizzy for having a headache, cataract, blurring of vision, optic atrohic blindness nyctalopia.
Herba Patriniae: pungent, bitter, is slightly cold, and returns stomach, large intestine, Liver Channel, heat-clearing and toxic substances removing, removing heat from blood, removing blood stasis and expelling pus, for acute appendicitis, and dysentery, enteritis, leucorrhea with red and white discharge, acute conjunctivitis, barrier film, bulbar conjunctiva polyp.
Above-mentioned various material combination uses, thus establish Herba Houttuyniae in formula, Herba Potentillae Discoloris, Herba pterocephali, Herba Taraxaci, Herba Violae, Cortex Ailanthi, Flos Chrysanthemi Indici, Herba Patriniae be monarch drug, but to ensure that heat-clearing and toxic substances removing of the present invention kills effect of staphylococcus; With Cortex Moutan, Rhizoma Ligustici, ebonyshoot mistletoe branchlet and leaf, Periostracum Cicadae, Folium Acori graminei, Nodus Nelumbinis Rhizomatis for ministerial drug, be intended to the merit playing clear wet heat extraction, eliminating pathogen in the liver detumescence, cooling blood for hemostasis, assist monarch drug, the strengthening efficacy of a drug; Herba Dianthi, Omphalia, Pheretima, Concha Haliotidis are adjuvant drug, play its relieving diarrhea with astringents, the length of diuretic antiinflammatory; Placenta Hominis, Rhizoma Polygonati coordinating the actions of various ingredients in a prescription are for making, invigorate blood circulation, QI invigorating, the characteristic that nourishes heart, to strengthen drug effect, above-mentioned each material combination science, rationally, the theory of Chinese medicine, gather heat-clearing and toxin-vanquishing, relaxing muscles and tendons to promote blood circulation, hepatic cholagogic and blood blood stasis dispelling effect altogether, be applicable to the prevention and therapy of poultry staphylococcosis.
positive beneficial effect of the present invention:
1. the present invention treats the Chinese medicine composition of poultry staphylococcosis, there is heat-clearing and toxin-vanquishing, relaxing muscles and tendons to promote blood circulation, hepatic cholagogic and blood blood stasis dispelling, strengthen the phagocytic function etc. of poultry macrophage, to poultry staphylococcosis epidemic prevention rate and cure rate all up to 100%, there is good prevention and therapy effect.
2. the present invention is except having prevention poultry staphylococcosis and occurring, and because containing multiple somatomedin in raw material, therefore to the growth promoter of poultry, improves meat, and improving immunity also has good effect.
3. the present invention adopts pure natural Chinese herbal medicine material combination, overcomes antibiotic drug resistance, does not have drug residue, does not pollute Fowl meat egg, and prevention and therapy is effective, have no side effect, cheap, and market application scenarios is wide.
Detailed description of the invention
Below in conjunction with some specific embodiments, the present invention is further described.
Embodiment 1
Treat a Chinese medicine composition for poultry staphylococcosis, be made up of the raw material of following weight:
Herba Houttuyniae 52g, Herba Potentillae Discoloris 55g, Cortex Moutan 50g, Herba pterocephali 20g, Rhizoma Ligustici 50g, ebonyshoot mistletoe branchlet and leaf 50g, Herba Taraxaci 45 g, Periostracum Cicadae 38g, Folium Acori graminei 40g part, Nodus Nelumbinis Rhizomatis 40g, Herba Dianthi 35 g, Herba Violae 40g, Omphalia 16 g, Cortex Ailanthi 31g, Placenta Hominis 25g, Rhizoma Polygonati 20g, Flos Chrysanthemi Indici 40g, Pheretima 20g, Concha Haliotidis 20g, Herba Patriniae 20g.
Preparation method: by each crude drug of above-mentioned parts by weight, dries, pulverized 40 ~ 80 orders, mix homogeneously, and to obtain final product.
Embodiment 2
Treat a Chinese medicine composition for poultry staphylococcosis, be made up of the raw material of following weight:
Herba Houttuyniae 55g, Herba Potentillae Discoloris 55g, Cortex Moutan 55g, Herba pterocephali 22g, Rhizoma Ligustici 50g, ebonyshoot mistletoe branchlet and leaf 55g, Herba Taraxaci 50g, Periostracum Cicadae 45g, Folium Acori graminei 45g part, Nodus Nelumbinis Rhizomatis 45g, Herba Dianthi 45g, Herba Violae 45g, Omphalia 18g, Cortex Ailanthi 35g, Placenta Hominis 25g, Rhizoma Polygonati 25g, Flos Chrysanthemi Indici 45g, Pheretima 25g, Concha Haliotidis 25g, Herba Patriniae 25g.
Preparation method is identical with embodiment 1.
Embodiment 3
Treat a Chinese medicine composition for poultry staphylococcosis, be made up of the raw material of following weight:
Herba Houttuyniae 60g, Herba Potentillae Discoloris 60g, Cortex Moutan 60g, Herba pterocephali 25g, Rhizoma Ligustici 60g, ebonyshoot mistletoe branchlet and leaf 60g, Herba Taraxaci 50g, Periostracum Cicadae 40g, Folium Acori graminei 50g part, Nodus Nelumbinis Rhizomatis 50g, Herba Dianthi 40g, Herba Violae 50g, Omphalia 20g, Cortex Ailanthi 40g, Placenta Hominis 30g, Rhizoma Polygonati 30g, Flos Chrysanthemi Indici 50g, Pheretima 30g, Concha Haliotidis 25g, Herba Patriniae 30g.
Preparation method is identical with embodiment 1.
Embodiment 4
Treat a Chinese medicine composition for poultry staphylococcosis, be made up of the raw material of following weight:
Herba Houttuyniae 61g, Herba Potentillae Discoloris 62g, Cortex Moutan 63g, Herba pterocephali 26 g, Rhizoma Ligustici 55g, ebonyshoot mistletoe branchlet and leaf 65g, Herba Taraxaci 50g, Periostracum Cicadae 45g, Folium Acori graminei 55g part, Nodus Nelumbinis Rhizomatis 51g, Herba Dianthi 42g, Herba Violae 47g, Omphalia 23g, Cortex Ailanthi 40g, Placenta Hominis 31g, Rhizoma Polygonati 35g, Flos Chrysanthemi Indici 53g, Pheretima 35g, Concha Haliotidis 28g, Herba Patriniae 33g.
Preparation method is identical with embodiment 1.
Embodiment 5
Treat a Chinese medicine composition for poultry staphylococcosis, be made up of the raw material of following weight:
Herba Houttuyniae 65g, Herba Potentillae Discoloris 65 g, Cortex Moutan 65 g, Herba pterocephali 30 g, Rhizoma Ligustici 60 g, ebonyshoot mistletoe branchlet and leaf 65 g, Herba Taraxaci 55 g, Periostracum Cicadae 50 g, Folium Acori graminei 55 g, Nodus Nelumbinis Rhizomatis 55 g, Herba Dianthi 45 g, Herba Violae 55 g, Omphalia 25 g, Cortex Ailanthi 42 g, Placenta Hominis 35 g, Rhizoma Polygonati 35 g, Flos Chrysanthemi Indici 55 g, Pheretima 35 g, Concha Haliotidis 30 g, Herba Patriniae 35 g.
Preparation method is identical with embodiment 1.
zoopery
Experimental animal: the chicken house at chicken staphylococcosis initial stage occurs in Anyang City.
Test method: the case of chicken staphylococcosis is made a definite diagnosis primarily of clinical symptoms, is then divided into 3 groups by testing crew by sick chicken at random, often organizes 500.
Testing 1 group for infecting matched group, not processing.
Testing 2 groups is experimental group, and the administration of the embodiment of the present invention 3 Chinese medicine composition, was mixed in feedstuff in one day of chicken by the ratio of feed relative 10%, mixes thoroughly, successive administration 5 days.
Testing 3 groups is matched group, and amoxicillin (100 g/ boxes, Zhengzhou Bary Animal Pharmaceutical Co., Ltd.), uses to specifications, and mixed drink, is watered the amount administration of 200 L, successive administration 5 days by 100 g.
The diagnosis clinical symptoms of chicken staphylococcosis:
Acute sepsis type: sick chicken performance spirit is depressed, stay vertical or squat, necking down is hung down wing, drowsiness, loss of appetite, feather pine disorderly, local has and comes off, and has mulberry blood sample exudate after ulceration, and inside the sick Chicken Wings of part, the hemorrhagic focus that differs in size and inflammatory necrosis appear in the area skin such as the apex of the wing, tail, head and neck, the back of the body and lower limb, local desiccation forms a scab, and 2-3 d is dead.
Arthritis type: the multiple chicken being born in 4-12 age in week, with toe and sole of the foot joint common, in aubergine or atropurpureus, some ulcerations tie black purple crust, some appearance toe tumors, sole enlargement, some toes purple darkly that necroses is drier and more astringent, and sick chicken performance is walked lamely, and lies prostrate more, become thin because searching for food difficulty, decline and death.
Omphalitis type: Embryo Gallus domesticus or newly go out the chickling annulus umbilicalis dysraphism of shell, namely omphalitis occurs after infecting staphylococcus, show as abdominal part and expand, umbilical opening enlargement inflammation, touch is hardened, and local is in yellowish red color or atropurpureus.Ophthalmia type: the upper and lower eyelid swelled of sick chicken, has purulent secretion to stick, eye conjunctiva is red and swollen, and the many secretions in canthus, even has blood, granuloma, course of disease elder enophthalmos, blind, and under some sockets of the eye, hole is swollen prominent.
Therapeutic effect decision method
Cure: medication postoperative infection chicken clinical symptom disappearance, appetite, spirit, wound etc. are recovered all to be judged as normally curing.
Effective: the clinical symptom relief such as waste absolutely, the lassitude of sick chicken food, incrustation after medication, search for food, spirit and traumatic event start to take a turn for the better, but do not return to all being judged to effectively of premorbid state.
Invalid: after medication, the symptom such as waste absolutely, the lassitude of sick chicken food, incrustation is not still felt any better and even worsened died, and it is invalid to be all judged as.
Result of the test is in table 1.
Table 1 Clinical efficacy result
。
Interpretation of result: by comparing with matched group, therapeutic effect and the average Gain weight of the embodiment of the present invention 3 Chinese medicine composition all reach desirable requirement, the clinical symptoms of morbidity chicken group obviously alleviates, and body weight increases good, and in one month, chicken group all occurs without epidemic disease; Amoxicillin treatment of control group effect is ideal, but chicken average weight gain is not high, and in one month, chicken group still has staphylococcosis to occur.
Claims (3)
1. treat a Chinese medicine composition for poultry staphylococcosis, it is characterized in that, be made up of the raw material of following parts by weight:
Herba Houttuyniae 52-65 part, Herba Potentillae Discoloris 55-65 part, Cortex Moutan 50-65 part, Herba pterocephali 20-30 part, Rhizoma Ligustici 50-60 part, ebonyshoot mistletoe branchlet and leaf 50-65 part, Herba Taraxaci 45-55 part, Periostracum Cicadae 38-50 part, Folium Acori graminei 40-55 part, Nodus Nelumbinis Rhizomatis 40-55 part, Herba Dianthi 35-45 part, Herba Violae 40-55 part, Omphalia 16-25 part, Cortex Ailanthi 31-42 part, Placenta Hominis 25-35 part, Rhizoma Polygonati 20-35 part, Flos Chrysanthemi Indici 40-55 part, Pheretima 20-35 part, Concha Haliotidis 20-30 part, Herba Patriniae 20-35 part.
2. the Chinese medicine composition for the treatment of poultry staphylococcosis according to claim 1, is characterized in that, is made up of the raw material of following parts by weight:
Herba Houttuyniae 60 parts, Herba Potentillae Discoloris 60 parts, Cortex Moutan 60 parts, Herba pterocephali 25 parts, Rhizoma Ligustici 60 parts, ebonyshoot mistletoe branchlet and leaf 60 parts, Herba Taraxaci 50 parts, Periostracum Cicadae 40 parts, Folium Acori graminei 50 parts, Nodus Nelumbinis Rhizomatis 50 parts, Herba Dianthi 40 parts, Herba Violae 50 parts, Omphalia 20 parts, Cortex Ailanthi 40 parts, Placenta Hominis 30 parts, Rhizoma Polygonati 30 parts, Flos Chrysanthemi Indici 50 parts, Pheretima 30 parts, Concha Haliotidis 25 parts, Herba Patriniae 30 parts.
3. the Chinese medicine composition for the treatment of poultry staphylococcosis according to claim 1, it is characterized in that, preparation method comprises the following steps: by each crude drug of described parts by weight, dries, pulverizes 40 ~ 80 orders, mix homogeneously, and to obtain final product.
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| WO2017093986A1 (en) * | 2015-12-05 | 2017-06-08 | Canabuzz-Med | Veterinary composition and methods for production and use |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579814A (en) * | 2012-03-19 | 2012-07-18 | 常熟华港制药有限公司 | Traditional Chinese medicine composition for treating streptococcicosis of poultry |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579814A (en) * | 2012-03-19 | 2012-07-18 | 常熟华港制药有限公司 | Traditional Chinese medicine composition for treating streptococcicosis of poultry |
Non-Patent Citations (1)
| Title |
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| 王成等: "《中兽医诊疗技术》", 31 August 2012 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017093986A1 (en) * | 2015-12-05 | 2017-06-08 | Canabuzz-Med | Veterinary composition and methods for production and use |
| US10675252B2 (en) | 2015-12-05 | 2020-06-09 | Canna-B Cure Ltd | Veterinary composition and methods for production and use |
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Application publication date: 20151104 |