CN104621155B - A kind of containing prothioconazoles and the bactericidal composition of Polyoxin and application - Google Patents
A kind of containing prothioconazoles and the bactericidal composition of Polyoxin and application Download PDFInfo
- Publication number
- CN104621155B CN104621155B CN201310574204.1A CN201310574204A CN104621155B CN 104621155 B CN104621155 B CN 104621155B CN 201310574204 A CN201310574204 A CN 201310574204A CN 104621155 B CN104621155 B CN 104621155B
- Authority
- CN
- China
- Prior art keywords
- polyoxin
- prothioconazoles
- bactericidal composition
- wettable powder
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of containing prothioconazoles and the bactericidal composition of Polyoxin and application.This bactericidal composition is with prothioconazoles and Polyoxin as principle active component.This bactericidal composition can be applicable to prevent and treat Cereal, fruit tree, vegetable disease, has higher synergistic function, overcomes and delayed the Drug resistance of pathogenic bacteria, and sterilization speed is fast, lasting period length, reduce application cost, and prevention effect is substantially better than its single dose and uses.The present invention may be used for preventing and treating the fungal disease on crops, being particularly useful for preventing and treating powdery mildew, banded sclerotial blight, droop, leaf spot, rust, sclerotiniose, net blotch, moire disease, gray mold, melasma, brown spot, balck shank, blossom rot, downy mildew and scab, effect is better than single dose and uses.
Description
Technical field:
The present invention relates to a kind of bactericidal composition and application thereof, especially one live with prothioconazoles and Polyoxin for main
The bactericidal composition of property composition and application thereof.
Background technology:
Prothioconazoles (Prothioconazole), is the New-type wide-spectrum triazolinthione series bactericidal agent developed by Beyer Co., Ltd, changes
Formal name used at school claims: 2-(2-(1-chlorine cyclopropyl)-3-(2-chlorphenyl)-2-hydroxypropyl-1-2-dihydro-3-1,2,4-triazole-3-sulfur generations, molecular formula:
C14H15Cl2N3OS.Structural formula is as follows:
The mechanism of action of prothioconazoles is precursor lanosterol or the 24-methylene dihydro of sterol in suppression fungus
Demethylation effect on Mi hair liquor-saturated l4 position, i.e. demethylation inhibitors (DMIs).In not only having well
Inhale activity, excellent protection, treat and root out activity, and the lasting period is long.By substantial amounts of field control effectiveness test,
Result shows that prothioconazoles not only has good safety to crop, and preventing disease theraping effect is good, and increases production bright
Aobvious, compared with triazole type biocide agent, prothioconazoles has broader spectrum of bactericidal activity.It is mainly used in preventing and treating cereal
Numerous diseases such as class crop such as Semen Tritici aestivi, Fructus Hordei Vulgaris, Brassica campestris L, Semen arachidis hypogaeae, Oryza sativa L. and legume crop.Almost to all wheats
Class disease has good prevention effect, as Semen Tritici aestivi and the powdery mildew of Fructus Hordei Vulgaris, banded sclerotial blight, droop, leaf spot,
Rust, sclerotiniose, net blotch, moire disease etc..Oil Lay and the soil-borne disease of Semen arachidis hypogaeae can also be prevented and treated, such as sclerotiniose,
And main foliage disease, such as gray mold, melasma, brown spot, balck shank, sclerotiniose and rust etc..
Polyoxin (Polyoxin), chemical name: 5-((2-amino-5-O-(amino carbonyl)-2-deoxidation-L-xylosyl)
Amino)-1,5-dideoxy-1-(3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1 (2H)-pyrimidine radicals) the other furan of-Β-D-
Alduronic acid.Structural formula:
The mechanism of action is the interference chitinous biosynthesis of pathogenic bacteria cell wall, and germ tube contacts after medicament with mycelia, office
Portion expands, rupture, overflow cell inclusion, and can not normal development, cause death, also have suppression pathogenic bacteria to produce
Spore and scab expansion effect.Preventing and treating wheat powdery mildew, Fructus Lycopersici esculenti blossom rot, Alternaria alternate, cucumber downy mildew,
Cucurbits fusarium wilt, rice sheath blight disease, alternaria leaf spot of apple, pear scab, melasma, gray mold etc. are multiple
Fungal disease.
The difficulty of prevention and cure of phytopathogen is increasing at present, on the one hand, along with the change of pattern of farming, melon fruits and vegetables etc.
Industrial crops cultivated area progressively expands, and disease occurrence degree, generation quantity all increase, and in preventing and treating, difficulty strengthens；
On the other hand, the resistance of pathogen rises under lasting medicament selection pressure year by year, and the prevention effect of single dose is had a greatly reduced quality,
Control of plant disease is faced with significant challenge.
Summary of the invention:
It is an object of the invention to provide a kind of applied widely, low cost for above-mentioned technical problem, effective containing rosickyite
Bacterium azoles and the plant bactericidal composition of Polyoxin.
It is a still further object of the present invention to provide this bactericidal composition and cause fungal disease medicine as preparation preventing and treating plant epiphyte
The application of thing, especially as preparation prevent and treat powdery mildew, banded sclerotial blight, droop, leaf spot, rust, sclerotiniose,
Net blotch, moire disease, gray mold, melasma, brown spot, balck shank, blossom rot, downy mildew and scab medicine
The application of thing.
It is an object of the invention to be realized by following measures:
A kind of containing prothioconazoles with the bactericidal composition of Polyoxin, wherein prothioconazoles with Polyoxin weight ratio is
1～70:1～50, preferably 1～35:1～25, more preferably 1～10:1～20, most preferably 1:2～6.
In the compositions of the present invention, both described prothioconazoles and Polyoxin account for the percentage by weight of compositions
5.5～80%, preferably 10～40%.
Described bactericidal composition is with prothioconazoles and Polyoxin for main active and known auxiliary agent and figuration
Agent is re-dubbed on pesticide the dosage form allowed.Auxiliary agent known to these has dispersant, diffusant, defoamer, wetting agent, collapses
Solve agent etc., calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, Ben-zylphenol Polyoxyethyl Ether, phenethyl can be used
Phenol polyethenoxy ether, fatty alcohol-polyoxyethylene ether and similar products thereof, aliphatic amine polyoxyethylene ether, fatty acid ethylene oxide
Addition product, polyoxyethylene polyoxy propylene ether, castor oil polyoxyethylene ether, NPE, TWEEN Series, fat
Fat polyoxyethylenated alcohol, Polyethylene Glycol series, Sulfonates, carboxylate, sulfate, phosphate, phosphite, wood
Mahogany sulfonate, xanthan gum, phenol formaldehyde condensate, ammonium salt, quaternary etc., excipient include Ketohexamethylene, dimethylbenzene,
Various solvent naphthas, water, antifreezing agent (such as propylene glycol), deionized water etc..Above auxiliary agent, excipient and other adjuvant can
With alone or and use.
Described bactericidal composition dosage form is cream, wettable powder, suspending agent, aqueous emulsion, microemulsion or water-dispersible
Granule.
Described bactericidal composition is as the application of preparation preventing and treating resistance plant fungal disease medicine.
Described bactericidal composition have as preparation prevent and treat powdery mildew, banded sclerotial blight, droop, leaf spot, rust,
Sclerotiniose, net blotch, moire disease, gray mold, melasma, brown spot, balck shank, blossom rot, downy mildew and
The application of scab medicine.
Beneficial effects of the present invention:
Bactericidal composition of the present invention is as the application of preparation preventing and treating resistance plant fungal disease medicine, anti-especially as preparation
Control powdery mildew, banded sclerotial blight, droop, leaf spot, rust, sclerotiniose, net blotch, moire disease, gray mold,
The application of melasma, brown spot, balck shank, blossom rot, downy mildew and scab medicine all has significant effect.This
Invention bactericidal composition can produce higher synergistic function, and activity is more than the activity of independent component.
Compared with prior art beneficial effects of the present invention: (1), compared with single dose, bactericidal composition antagonism of the present invention is true
Fungus diseases such as powdery mildew, banded sclerotial blight, droop, leaf spot, rust, sclerotiniose, net blotch, moire disease, ash
Mildew, melasma, brown spot, balck shank, blossom rot, downy mildew, scab have obvious synergistic function, bright
Show and improve prevention effect；(2) preventing and treating recruitment, drug cost are reduced；(3) alternative routine and the agriculture being easily generated resistance
Medicine；(4) compared with single dose, produce and use cost reduces；(5) the suppression drug-fast generation of fungus, its effect is obvious
Use higher than its single dose.
Detailed description of the invention:
Below in conjunction with embodiment, the invention will be further described, and in embodiment, the preparation method of dosage form is conventional method,
" % " of the present invention is mass percent.
Two kinds of reactive compounds can be processed into any one dosage form of permission, illustrates that two kinds have with specific embodiment below
The preparation that effect composition is processed into, but the preparation that these two kinds of active component can be processed is not limited only to set forth below.
Embodiment 1:
By prothioconazoles 5g, Polyoxin 10g, detergent LS (to methoxyl group fatty acid amido benzene sulfonic acid sodium salt) 2g,
Dispersing agent NNO (sodium methylene bis-naphthalene sulfonate) 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out air-flow powder
Broken, preparing effective ingredient weight percentage is 15% wettable powder.
Embodiment 2:
By prothioconazoles 3g, Polyoxin 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g,
Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient weight percentage is 15% wettable powder.
Embodiment 3:
By prothioconazoles 2g, Polyoxin 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g,
Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient weight percentage is 14% wettable powder.
Embodiment 4:
Weigh 5g prothioconazoles, 50g Polyoxin, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g,
Alkylphenol polyoxyethylene 1g, solvent naphtha 13g, add water to 100g.The method that above raw material is prepared aqueous emulsion routinely
Putting into the mixing of mixing kettle high speed, making effective Ingredients Weight percentage composition is 55% prothioconazoles-Polyoxin water and milk
Agent.
Embodiment 5:
Weigh 2g prothioconazoles, 30g Polyoxin, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphorus
Acid esters 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.By above raw material
The method preparing microemulsion routinely puts into mixing in mixing kettle, and making effective Ingredients Weight percentage composition is 32% rosickyite bacterium
Azoles-Polyoxin microemulsion.
Embodiment 6:
Weigh 1g prothioconazoles, 5g Polyoxin, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkane
Base phenol polyethenoxy ether 1g, solvent naphtha 13g, add water to 100g.The method that above raw material is prepared aqueous emulsion routinely is thrown
Entering the mixing of mixing kettle high speed, making effective Ingredients Weight percentage composition is 6% prothioconazoles-Polyoxin aqueous emulsion.
Embodiment 7:
Weigh 50g prothioconazoles, 20g Polyoxin, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 2g,
Castor oil polyoxyethylene ether 2g, solvent naphtha are to 100g.The method that above raw material is prepared cream routinely puts into mixing kettle
Middle mixing, making effective Ingredients Weight percentage composition is 70% prothioconazoles-Polyoxin cream.
Embodiment 8:
Weigh 2g prothioconazoles, 40g Polyoxin, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 5g,
Solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, makes effective ingredient weight
Amount percentage composition is 42% prothioconazoles-Polyoxin cream.
Embodiment 9:
Weigh 5g prothioconazoles, 20g Polyoxin, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphorus
Acid esters 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.By above raw material
The method preparing microemulsion routinely puts into mixing in mixing kettle, and making effective Ingredients Weight percentage composition is 25% rosickyite bacterium
Azoles-Polyoxin microemulsion.
Embodiment 10:
Weigh 5g prothioconazoles, 0.5g Polyoxin, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 7g,
Solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, makes effective ingredient weight
Amount percentage composition is 5.5% prothioconazoles-Polyoxin cream.
Embodiment 11:
Weigh 5g prothioconazoles, 30g Polyoxin, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g,
Solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, makes effective ingredient weight
Amount percentage composition is 35% prothioconazoles-Polyoxin cream.
Embodiment 12:
Weigh 10g prothioconazoles, 10g Polyoxin, lignin 2g, polyoxyethylene poly-oxygen propylene aether 4g, xanthan gum
0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, in the effect of sand mill
Under to make effective Ingredients Weight percentage composition be 20% prothioconazoles-Polyoxin suspending agent.
Embodiment 13:
Weigh 30g prothioconazoles, 12g Polyoxin, lignin 2g, polyoxyethylene poly-oxygen propylene aether 4g, xanthan gum
0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, in the effect of sand mill
Under to make effective Ingredients Weight percentage composition be 42% prothioconazoles-Polyoxin suspending agent.
Embodiment 14:
Weigh 2g prothioconazoles, 5g Polyoxin, sodium lignin sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate
5g, polyvinyl alcohol 5g, Borax 2g, white carbon 3g, kieselguhr complement to 100g, above raw material are pressed water dispersible granular
It is 7% prothioconazoles-Polyoxin water dispersion granule that agent method makes effective Ingredients Weight percentage composition.
Embodiment 15:
Weigh 4g prothioconazoles, 13g Polyoxin, sodium lignin sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate
5g, polyvinyl alcohol 5g, Borax 2g, kieselguhr 28g complement to 100g, and above raw material is pressed water dispersible granular agent method
Making effective Ingredients Weight percentage composition is 17% prothioconazoles-Polyoxin water dispersion granule.
Embodiment 16:
Weigh 5g prothioconazoles, 15g Polyoxin, lignin 2g, polyoxyethylene poly-oxygen propylene aether 4g, xanthan gum 0.15g,
Ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, make under the effect of sand mill
Effective ingredient weight percentage is 20% prothioconazoles-Polyoxin suspending agent.
Field control effectiveness test:
1. test processes: the difference of each composition of this experimental evidence sets three dosings respectively, and dosing is effectively to become
Divide prothioconazoles (A) and the quality sum of effective ingredient Polyoxin (B).Comparison medicament is pesticide single dose more than 10% respectively
Oxymycin WP and 5% prothioconazoles ME and blank clean water experiment.
2. test method: each plot area is 66.7m2, it is repeated 3 times；Investigation drug effect after investigating before dispenser and preventing and treating
Method is: randomization 5 point in test treatment region, carries out severity Scaling according to country's field test relevant criterion, meter
Calculate preventive effect.Result of the test see table:
Table 1 field control effectiveness test result
Being shown by field efficacy result, as shown in Table 1, the present composition has obvious synergistic function, group
The prevention effect of compound is excellent, and prevention effect is all better than single dose kind, has using value in agricultural is applied.
Claims (3)
1. one kind contains prothioconazoles and the wettable powder of Polyoxin, it is characterized in that: this wettable powder be by prothioconazoles 5g, Polyoxin 10g, to methoxyl group fatty acid amido benzene sulfonic acid sodium salt 2g, sodium methylene bis-naphthalene sulfonate 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient weight percentage is 15% wettable powder.
2. one kind contains prothioconazoles and the wettable powder of Polyoxin, it is characterized in that: this wettable powder is by prothioconazoles 3g, Polyoxin 12g, sodium lauryl sulphate 3g, sodium methylene bis-naphthalene sulfonate 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient weight percentage is 15% wettable powder.
3. one kind contains prothioconazoles and the wettable powder of Polyoxin, it is characterized in that: this wettable powder is by prothioconazoles 2g, Polyoxin 12g, sodium lauryl sulphate 3g, sodium methylene bis-naphthalene sulfonate 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient weight percentage is 14% wettable powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310574204.1A CN104621155B (en) | 2013-11-15 | 2013-11-15 | A kind of containing prothioconazoles and the bactericidal composition of Polyoxin and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310574204.1A CN104621155B (en) | 2013-11-15 | 2013-11-15 | A kind of containing prothioconazoles and the bactericidal composition of Polyoxin and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104621155A CN104621155A (en) | 2015-05-20 |
| CN104621155B true CN104621155B (en) | 2016-08-17 |
Family
ID=53200807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310574204.1A Active CN104621155B (en) | 2013-11-15 | 2013-11-15 | A kind of containing prothioconazoles and the bactericidal composition of Polyoxin and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104621155B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104012555A (en) * | 2014-06-25 | 2014-09-03 | 深圳诺普信农化股份有限公司 | Agricultural sterilization composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003073852A2 (en) * | 2002-03-01 | 2003-09-12 | Basf Aktiengesellschaft | Fungicidal mixtures based on prothioconazole and a strobilurin derivative |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN103228140A (en) * | 2010-08-05 | 2013-07-31 | 拜耳知识产权有限责任公司 | Active compound combinations comprising prothioconazole and fluxapyroxad |
-
2013
- 2013-11-15 CN CN201310574204.1A patent/CN104621155B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003073852A2 (en) * | 2002-03-01 | 2003-09-12 | Basf Aktiengesellschaft | Fungicidal mixtures based on prothioconazole and a strobilurin derivative |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN103228140A (en) * | 2010-08-05 | 2013-07-31 | 拜耳知识产权有限责任公司 | Active compound combinations comprising prothioconazole and fluxapyroxad |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104621155A (en) | 2015-05-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105766959A (en) | Sterilization composition containing isopyrazam and carbendazim and application of sterilization composition | |
| CN105766952B (en) | The bactericidal composition and its application of a kind of Fluxapyroxad-containsterilization and folpet | |
| CN104642331A (en) | Bactericidal composition containing prothioconazole and tebuconazole and application thereof | |
| CN104621123B (en) | A kind of bactericidal composition containing prothioconazoles and fluopicolide and application thereof | |
| CN104621126A (en) | Sterilization composition containing prothioconazole and difenoconazole and application thereof | |
| CN105766933A (en) | Bixafen and prothioconazole containing bactericidal composition and application thereof | |
| CN104621168A (en) | Sterilization composition containing prothioconazole and prochloraz-manganese chloride and application thereof | |
| CN104621155B (en) | A kind of containing prothioconazoles and the bactericidal composition of Polyoxin and application | |
| CN104642335B (en) | A kind of bactericidal composition containing prothioconazoles and bupirimate and application thereof | |
| CN105794794A (en) | Bactericidal composition containing isopyrazam and tiadinil and application of bactericidal composition | |
| CN106212474A (en) | A kind of Fluxapyroxad-containsterilization and the bactericidal composition of cycloheximide triazole and application thereof | |
| CN104621154B (en) | A kind of bactericidal composition containing prothioconazoles and benzene metsulfovax and application thereof | |
| CN106889079B (en) | A kind of bactericidal composition and its application containing fluoxastrobin and alkene oxime amine | |
| CN104642333A (en) | Prothioconazole and kresoxim-methyl-containing sterilization composition and application thereof | |
| CN104621129A (en) | Sterilization composition containing prothioconazole and metalaxyl-M and application thereof | |
| CN104621153B (en) | A kind of bactericidal composition containing prothioconazoles and Propamocarb and application thereof | |
| CN106135223A (en) | A kind of containing Boscalid and the bactericidal composition of prothioconazoles and application | |
| CN105360128B (en) | A kind of bactericidal composition and its application containing mepanipyrim and Boscalid | |
| CN105794792B (en) | The bactericidal composition and its application of a kind of Fluxapyroxad-containsterilization and Wakil | |
| CN106135225A (en) | A kind of bactericidal composition containing Boscalid and Difenoconazole and application thereof | |
| CN106135212A (en) | A kind of containing Boscalid and the bactericidal composition of kresoxim-methyl and application | |
| CN104642332A (en) | Bactericidal composition containing prothioconazole and diniconazole and application thereof | |
| CN106106502A (en) | A kind of Fluxapyroxad-containsterilization and the bactericidal composition of simeconazoles and application thereof | |
| CN106538567A (en) | The bactericidal composition and its application of a kind of containing fluopyram and polyoxin | |
| CN106135241A (en) | A kind of containing Boscalid and the bactericidal composition of Polyoxin and application |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |