CN104606253A - Method for processing periplaneta americana - Google Patents
Method for processing periplaneta americana Download PDFInfo
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- CN104606253A CN104606253A CN201510096353.0A CN201510096353A CN104606253A CN 104606253 A CN104606253 A CN 104606253A CN 201510096353 A CN201510096353 A CN 201510096353A CN 104606253 A CN104606253 A CN 104606253A
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- periplaneta americana
- milk
- boils
- dead
- scalds
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Abstract
The invention provides a method for processing periplaneta americana. The method is characterized in that live periplaneta americana is scalded with boiling milk and dried. The periplaneta americana processed by the method is good in curative effect, small in peculiar smell during oral administration and high in compliance of patients.
Description
Invention field
The present invention relates to medicine, particularly the processing method of a kind of periplaneta americana, belong to medical art.
Background technology
Periplaneta americana belongs to Insecta, Blattaria Blattidae animal, and " Blatta seu periplaneta " is loaded in Shennong's Herbal for its popular name, the beginning of being used as medicine, and is listed in middle product, meaning " taste: salty, cold; Control: the hard cold and heat of Blood stasis, removing mass are poly-, laryngopharynx numbness, endogenous cold loss of fecundity ".Now there are some researches show, the large sickle in America has and has good tissue repair activity and hepatoprotective effect to various traumatic surface and digestive tract ulcer.
The concocting method of the large sickle in prior art America, is to kill by soak with ethanol after catching or boiling water scalds dead, dries or dry.With the large sickle in America of prior art processing, abnormal flavour is extra heavy, and mouthfeel is very poor, directly affects the compliance of patient.
Summary of the invention
The object of this invention is to provide the processing method of a kind of periplaneta americana, the oral abnormal flavour of periplaneta americana that the method obtains is little, and mouthfeel is good, and curative effect is high, and the compliance of patient is high.
The object of the present invention is achieved like this:
A processing method for periplaneta americana, is characterized in that: the periplaneta americana milk that boils of living scalds dead, dry.
Below by test example, usefulness of the present invention is described.Test example is intended to further illustrate beneficial effect of the present invention below, but not restriction of the present invention.
Test example one, different processing methods mouthfeel compare
1, by same mass products periplaneta americana, concoct by the following method.
1) boiling water scalds dead oven dry: periplaneta americana boiling water of living scalds dead, and less than 60 DEG C oven dry, pulverize;
2) milk that boils scalds dead oven dry: the periplaneta americana milk that boils of living scalds dead, and less than 60 DEG C oven dry, pulverize.
2, mouthfeel evaluation is made up of 10 people and appraises group through discussion, everyone boiling water that warm water for oral use is mixed well respectively scalds milk of extremely drying and boil and scalds dead periplaneta americana powder of drying, and evaluates the mouthfeel mouthfeel such as " free from extraneous odour ", " abnormal flavour is little ", " can accept ", " abnormal flavour is large ", " abnormal flavour is very large ".Evaluation result is in table 1
The periplaneta americana mouthfeel of table 1 different processing methods compares
| Free from extraneous odour | Abnormal flavour is little | Can accept | Abnormal flavour is large | Abnormal flavour is very large | |
| The milk that boils scalds dead oven dry | 1 people | 9 people | |||
| Boiling water scalds dead oven dry | 3 people | 7 people |
Result shows, and the milk that boils scalds dead periplaneta americana of drying, and oral abnormal flavour is little, and mouthfeel is good.
Test example two, different processing methods compare the protective effect that ethanol causes gastric mucosa damage.
1, by same mass products periplaneta americana, process by the following method.
1) soak with ethanol kills lyophilizing: kill by soak with ethanol, lyophilizing, pulverizes;
2) milk that boils scalds dead lyophilizing: scald dead with the milk that boils, take out, lyophilizing, pulverize.
2, to ethanol cause gastric mucosa damage protective effect compare
Choose healthy SD rat, male and female half and half, weight 180-220g, be divided into soak with ethanol to kill lyophilizing group at random, the milk that boils scalds dead lyophilizing group, matched group, often organize 10, every day gastric infusion 1 time, 1 2mg/kg, continuous 7 days, matched group gave equivalent distilled water.Before experiment, the first fasting 48h of rat, freely drinks water, after last administration, 1h every rat oral gavage dehydrated alcohol 1mL/ only, take off cervical vertebra after 1h and put to death animal, close cardia by clip, inject 1% formaldehyde 5mL from pylorus, folder closes pylorus again, put into 1% formalin and fix 10min, cut off coat of the stomach along greater gastric curvature, measure damaged length, as gastric mucosal damage index, and suppression ratio is calculated using damaged length (width is greater than 1 mm to be doubled) summation.The results are shown in Table 2.
Suppression ratio (%)=(matched group ulcer index one administration group ulcer index) ÷ matched group ulcer index × 100%.
Table 2 different processing methods compares the protective effect that ethanol causes gastric mucosa damage
| Group | Dosage | Gastric mucosal damage index (mm) | Suppression ratio (%) |
| Matched group | 125.6±14.9 | ||
| Soak with ethanol kills lyophilizing group | 2mg/kg | 59.7±13.6 | 52.47 |
| The milk that boils kills lyophilizing group | 2mg/kg | 51.2±10.8 | 59.24 |
Result shows, the periplaneta americana that the milk that boils kills lyophilizing is better than to the protective effect that ethanol causes gastric mucosa damage the periplaneta americana that soak with ethanol kills lyophilizing.
Test example three, different processing methods liver protective effect compare
1, by same mass products periplaneta americana, concoct by the following method.
1) boiling water scalds dead oven dry: scald with boiling water dead, less than 60 DEG C oven dry, pulverize;
2) milk that boils scalds dead oven dry: scald dead with the milk that boils, less than 60 DEG C oven dry, pulverize.
2, to CCl
4the impact test of caused Liver Damage in Rats.
The healthy SD rat of body weight 180-220g, is divided into that boiling water scalds dead oven dry group, the milk that boils scalds dead oven dry group, matched group at random, often organizes 10; Contrast with test group in experiment the 1st, 5 days subcutaneous injection 50%CCl
4vegetable oil suspension 5mL/kg, difference gastric infusion every day 1 time from experiment starts day, 1 3g/kg, matched group gives equal-volume distilled water, continuous 9 days, and drug withdrawal 24 hours eye sockets get blood, survey serum glutamic pyruvic transminase with reitman-frankel method.The results are shown in Table 3.
Table 3 different processing methods is to CCl
4the impact of caused hepatic injury rat blood serum glutamate pyruvate transaminase
| Group | Dosage (g/kg) | Glutamate pyruvate transaminase in serum |
| Matched group | 352.7±123.6 | |
| Boiling water scalds dead oven dry group | 3 | 185.2±119.4 |
| The milk that boils scalds dead oven dry group | 3 | 165.4±108.7 |
Result shows, the milk that boils scalds dead periplaneta americana of drying to rat CCl
4the protective effect of caused hepatic injury is better than, and boiling water scalds dead periplaneta americana of drying.
Detailed description of the invention
embodiment 1
Live periplaneta americana, scalds dead, lyophilizing in the milk that boils.
embodiment 2
Live periplaneta americana, scalds dead, less than 60 DEG C oven dry in the milk that boils.
embodiment 3
Live periplaneta americana, scalds dead, put in freeze dryer, be refrigerated to less than-10 DEG C, be evacuated to below drying chamber pressure 30Pa, subliming by heating in the milk that boils; The temperature of distillation should control below 40 DEG C, and the temperature of resolution phase controls below 45 DEG C, to dry.
embodiment 4
Live periplaneta americana, scalds dead, vacuum drying in the milk that boils.
embodiment 5
Live periplaneta americana, scalds dead, dry in the milk that boils.
embodiment 6
Live periplaneta americana, scalds dead, dry in the milk that boils.
Claims (1)
1. a processing method for periplaneta americana, is characterized in that: the periplaneta americana milk that boils of living scalds dead, dry.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510096353.0A CN104606253A (en) | 2015-03-05 | 2015-03-05 | Method for processing periplaneta americana |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510096353.0A CN104606253A (en) | 2015-03-05 | 2015-03-05 | Method for processing periplaneta americana |
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| CN104606253A true CN104606253A (en) | 2015-05-13 |
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| CN201510096353.0A Pending CN104606253A (en) | 2015-03-05 | 2015-03-05 | Method for processing periplaneta americana |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101167749A (en) * | 2007-11-09 | 2008-04-30 | 重庆医药工业研究院有限责任公司 | Preparing method for improving toad venom taste |
| CN101884406A (en) * | 2009-05-12 | 2010-11-17 | 刘凤鸣 | Taste-masking technology by taking milk powder as taste-masking agent and application thereof |
| CN103891895A (en) * | 2012-12-31 | 2014-07-02 | 内蒙古伊利实业集团股份有限公司 | Liquid dairy product containing earthworm protein and preparation method of liquid dairy product |
-
2015
- 2015-03-05 CN CN201510096353.0A patent/CN104606253A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101167749A (en) * | 2007-11-09 | 2008-04-30 | 重庆医药工业研究院有限责任公司 | Preparing method for improving toad venom taste |
| CN101884406A (en) * | 2009-05-12 | 2010-11-17 | 刘凤鸣 | Taste-masking technology by taking milk powder as taste-masking agent and application thereof |
| CN103891895A (en) * | 2012-12-31 | 2014-07-02 | 内蒙古伊利实业集团股份有限公司 | Liquid dairy product containing earthworm protein and preparation method of liquid dairy product |
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Application publication date: 20150513 |
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| WD01 | Invention patent application deemed withdrawn after publication |