CN104605195A - Additive for feed for weaned pigs as well as preparation method and application of additive - Google Patents

Additive for feed for weaned pigs as well as preparation method and application of additive Download PDF

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CN104605195A
CN104605195A CN201510025538.2A CN201510025538A CN104605195A CN 104605195 A CN104605195 A CN 104605195A CN 201510025538 A CN201510025538 A CN 201510025538A CN 104605195 A CN104605195 A CN 104605195A
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feed
feed additive
additive
weaning
weaning piglet
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CN104605195B (en
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王定发
周汉林
周璐丽
侯冠彧
周雄
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Tropical Crops Genetic Resources Institute CATAS
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Tropical Crops Genetic Resources Institute CATAS
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Abstract

The invention relates to the field of livestock feed additives, and discloses an additive for feed for weaned pigs as well as a preparation method and an application of the additive. Piper sarmentosum extract and carriers are added to the additive, the prepared feed additive can be directly added to the feed for the weaned pigs, accordingly, the growth performance of the weaned pigs can be improved, the antioxidation, anti-inflammatory and immunity ability of the weaned pigs is enhanced, the application is convenient, and the effect is remarkable. With adding of the additive for the feed for the weaned pigs, the working difficulty of feeding of the weaned pigs is reduced, and the feeding cost is saved.

Description

A kind of feed additive for weaning piglet and its preparation method and application
Technical field
The present invention relates to pig domestic animal feed additive field, refer to a kind of feed additive for weaning piglet and its preparation method and application especially.
Background technology
Jia Betel ( piper sarmentosum), be the plant of Piperaceae Piper, be distributed widely in the ground such as Yunnan, Guizhou, Fujian, Tibet, Guangdong, Guangxi of India, Vietnam, Indonesia, Philippine, Papua New Guinea, Malaysia and China's Mainland.Investigation shows, in Hainan Province based in the Eco-Environment System of artificial natural rubber woods, false Betel plant distributions occupancy volume, in occupation of the maximum group in shade plants kind, distributes comparatively extensive.
It is reported that each tissues such as , Jia Betel root, stem, leaf, fruit ear have detoxification sore treatment effect, take orally and effectively can treat the illnesss such as abdominal distension, enteritis, diarrhea, rheumatalgia, external application can treat hemorrhage, become silted up blue or green and the pernio etc. that wound causes.Recent study shows, Folium Piperis sarmentosi water-soluble extractive has anti-inflammatory activity, and the amides compound in its extract has significantly anti-oxidant, resistive connection nuclearity effect.
Weaned piglet is a vital stage in feeding piglet process.In wean process, owing to progressively adding feed in food, the incidence of the diseases such as grice diarrhoea increases greatly, and growth performance reduces greatly, has had a strong impact on growing of piglet.Therefore, improve weanling pig intestinal immunity for early-weaned piglets spend smoothly early weaning close most important.
Summary of the invention
The present invention proposes a kind of feed additive for weaning piglet and its preparation method and application, there is the effect improving weanling pig immunity, improve piglet growth performance.
Technical scheme of the present invention is achieved in that
A kind of feed additive for weaning piglet, comprises following component: Jia Betel extract and carrier.
Further, described Jia Betel extract formulation, comprises component: Jia Betel extract 1-3 part of following parts by weight, carrier 1-3 part.
Further, described carrier is silica or calcium carbonate.
Further, described Jia Betel extract is made as dry in the shade Folium Piperis sarmentosi sheet supercritical carbon dioxide extraction method or soxhlet extraction and obtains Jia Betel extract.
The preparation method of described feed additive for weaning piglet, comprises the following steps:
Get formula ratio Jia Betel extract and carrier, mix, obtain feed additive for weaning piglet of the present invention.
Described feed additive for weaning piglet improves the application on the feed of Growth Performance of Weaning Piglets in preparation.
Described feed additive for weaning piglet improves the application on the feed of weanling pig immunity in preparation.
Described feed additive for weaning piglet improves the application on the feed of weanling pig anti-inflammatory power in preparation.
Described feed additive for weaning piglet improves the application on the feed of oxidation resistance in preparation.
Further, described feed additive for weaning piglet consumption is that per kilogram feed adds 100-200 mg.
Beneficial effect of the present invention:
Feed additive for weaning piglet of the present invention, wherein in Jia Betel extract containing the plurality of active ingredients such as asarone, cinnamic acid, myristicin, carypohyllene, phellandrene, have anti-inflammation, anti-oxidant, promote the effects such as peristalsis of the digest tract.But because gained Jia Betel extract is oily, adds in feed and be difficult to mix, affect quality of the fodder, be also unfavorable for that piglet searches for food.The carrier added in the present invention has the effect of absorption, dilution, can adsorb the false Betel extract of oily, produces caking after can effectively avoiding adding in feed, occurs mixing the problems such as uneven.
The feed additive for weaning piglet that the present invention proposes, add in weanling pig feed, the growth performance of weanling pig increases greatly, oxidation resistance, anti-inflammatory power and immunity are improved, effectively can improve the digestive system function of weanling pig, strengthen weanling pig to the resistivity of disease, the weanling pig that helps reducing various disease spends the early weaning phase smoothly, reduce the work difficulty of weaning pig feeding, save feeding cost.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of feed additive for weaning piglet, comprises following component: Jia Betel extract 10 g, silica 10 g; Described Jia Betel extract is made as the Folium Piperis sarmentosi sheet supercritical carbon dioxide extraction method that dries in the shade and obtains Jia Betel extract; The granularity of concrete extraction conditions following: Jia Betel cauline leaf powder is 20-40 order, and extracting pressure is 15-40MPa, and extraction temperature is 35-60 ° of C, and carbon dioxide flow is 40-60L/h, and extraction time is 1.0-3.0 h.
The preparation method of described feed additive for weaning piglet, comprises the following steps:
Get oily Jia Betel extract and the carrier of formula ratio, mix, obtain feed additive for weaning piglet of the present invention.
Above-mentioned obtained feed additive for weaning piglet, can directly add in weanling pig feed, addition is that per kilogram feed adds 100 mg, and obtained feed has raising pigling immunity, anti-inflammatory power, oxidation resistance, and can improve the growth performance of weanling pig.
Embodiment 2
A kind of feed additive for weaning piglet, comprise following component: Jia Betel extract 30 g, silica or calcium carbonate 10 g, described Jia Betel extract is made as the oily Jia Betel thing that the Folium Piperis sarmentosi sheet supercritical carbon dioxide extraction method that dries in the shade obtains; Concrete extraction conditions is identical with embodiment 1
The preparation method of described feed additive for weaning piglet, comprises the following steps:
Get formula ratio Jia Betel extract and carrier, mix, obtain feed additive for weaning piglet of the present invention.
Above-mentioned obtained feed additive for weaning piglet, can directly add in weanling pig feed, addition is that per kilogram feed adds 100 mg, and obtained feed has raising pigling immunity, improves piglet growth performance, and can improve anti-oxidant, the anti-inflammatory power of weanling pig.
Embodiment 3
A kind of feed additive for weaning piglet, comprise following component: Jia Betel extract 10 g, silica 30 g, described Jia Betel extract is made as the oily Jia Betel thing that Folium Piperis sarmentosi sheet soxhlet extraction method of drying in the shade obtains; Concrete operations condition is the granularity of: Jia Betel cauline leaf powder is 20-40 order, adds the ethanol that volumetric concentration is 70-80%, Soxhlet backflow 2-3 h, obtained in oily Jia Betel extract.
The preparation method of described feed additive for weaning piglet, comprises the following steps:
Get formula ratio Jia Betel extract and carrier, mix, obtain feed additive for weaning piglet of the present invention.
Above-mentioned obtained feed additive for weaning piglet, can directly add in weanling pig feed, addition is that per kilogram feed adds 200 mg, and obtained feed has raising pigling immunity, improves piglet growth performance, and can improve anti-oxidant, the anti-inflammatory power of weanling pig.
Embodiment 4
A kind of feed additive for weaning piglet, comprise following component: Jia Betel extract 20 g, silica 30 g, described Jia Betel extract is made as the Folium Piperis sarmentosi sheet supercritical carbon dioxide extraction method that dries in the shade and obtains Jia Betel thing; Concrete extraction conditions is identical with embodiment 1.
The preparation method of described feed additive for weaning piglet, comprises the following steps:
Get formula ratio Jia Betel extract and carrier, mix, obtain feed additive for weaning piglet of the present invention.
Above-mentioned obtained feed additive for weaning piglet, can directly add in weanling pig feed, addition is that per kilogram feed adds 150 mg, and obtained feed has raising pigling immunity, improves piglet growth performance, and can improve anti-oxidant, the anti-inflammatory power of weanling pig.
Embodiment 5
A kind of feed additive for weaning piglet, comprise following component: Jia Betel extract 30 g, calcium carbonate 20 g, described Jia Betel extract is made as the Folium Piperis sarmentosi sheet soxhlet extraction that dries in the shade and obtains Jia Betel thing.
The preparation method of described feed additive for weaning piglet, comprises the following steps:
Get formula ratio Jia Betel extract and carrier, mix, obtain feed additive for weaning piglet of the present invention.
Above-mentioned obtained feed additive for weaning piglet, can directly add in weanling pig feed, addition is that per kilogram feed adds 100 mg, and obtained feed has raising pigling immunity, improves piglet growth performance, and can improve anti-oxidant, the anti-inflammatory power of weanling pig.
Addition is on the impact of Growth Performance of Weaning Piglets
Choose the comparatively close weanling pig of parity, Confinement Time (21d wean) 80, be divided into 4 processed group, i.e. control groups at random, process 1 group (T100), process 2 groups (T200), process 3 groups (T400), each process 4 repetition, often repeats 5 pigs, often repeats separated raising.Control group fed sucking pig material, processes feed additive for weaning piglet 100,200 and 400 mg/kg that 1 group, 2 groups, 3 groups are added embodiment 1 gained respectively in sucking pig material.All piglets let alone free choice feeding and drinking-water, and feed 29 d.Any other medicines additive is no longer added in sucking pig material.
Respectively in same day on-test and 30d early morning, in units of each repetition, weigh piglet empty body weight; Every day weighs feed relative in units of each repetition, record piglet feed intake.Investigate different disposal to the impact of piglet growth performance.It the results are shown in Table 1.
Table 1 feed addictive addition is on the impact of Growth Performance of Weaning Piglets
Group Control group T100 T200 T400
First starting weight (kg) 6.39±0.01 6.43±0.03 6.47±0.06 6.43±0.05
Terminate heavy (kg) 12.84±0.86ab 13.89±0.08a 12.24±0.31b 12.85±0.34ab
Average daily gain (g) 222.56±19.74b 257.39±3.65a 198.99±8.48b 221.52±10.03b
Average daily ingestion amount (g) 373.55±1.75c 421.95±4.63a 331.20±6.43d 387.64±5.63b
Feed-weight ratio 1.70±0.04 1.64±0.04 1.67±0.10 1.75±0.10
Note: the different lowercase alphabet of colleague's data mark show significant difference ( p<0.05), containing identical lowercase or without letter representation difference not significantly ( p>0.05).
Result shows, the group piglet of adding 100 mg/kg and 200 mg/kg feed additive for weaning piglet has higher average daily gain, and feed-weight ratio also decreases; And add the group of 400 mg/kg feed additive for weaning piglet, although piglet average daily gain is also improved, feed-weight ratio is higher.Therefore consider feed cost, the addition of feed additive for weaning piglet described in the present invention is 100-200 mg/kg.
The feed additive for weaning piglet of gained of the present invention is on the impact of Growth Performance of Weaning Piglets
Choose the comparatively close weanling pig of parity, Confinement Time (21d wean) 120, be divided into 6 processed group at random, i.e. control group, processes 1 group (T1), processes 2 groups (T2), process 3 groups (T3), process 4 groups (T4), process 5 groups (T5), each process 4 repetition, often repeat 5 pigs, often repeat separated raising.Control group fed sucking pig material, 5 processed group add the obtained feed addictive of 5 embodiments respectively at sucking pig material respectively, and add in weanling pig feed according to corresponding additive capacity.All piglets let alone free choice feeding and drinking-water, and feed 29d.Any other medicines additive is no longer added in sucking pig material.
Respectively in same day on-test and the 30th d off-test in early morning, in units of each repetition, weigh piglet empty body weight; Every day weighs feed relative in units of each repetition, record piglet feed intake.Investigate different disposal to the impact of piglet growth performance.It the results are shown in Table 2.
The feed addictive of table 2 gained of the present invention is on the impact of Growth Performance of Weaning Piglets
Group First starting weight (kg) Terminate heavy (kg) Average daily gain (g) Average daily ingestion amount (g) Feed-weight ratio
Control group 6.39±0.01 12.84±0.86 222.56±19.74bc 373.55±1.75c 1.70±0.04
T1 6.43±0.03 13.89±0.08 257.39±3.65a 421.95±4.63a 1.64±0.04
T2 6.41±0.07 13.09±0.25 230.27±6.58bc 390.65±4.10b 1.70±0.06
T3 6.47±0.10 13.09±0.18 228.39±6.79bc 386.33±6.07b 1.69±0.06
T4 6.45±0.06 13.45±0.20 241.46±5.36b 396.33±4.92b 1.64±0.04
T5 6.45±0.08 13.32±0.34 236.76±9.34bc 389.33±7.79b 1.64±0.03
Note: with the different lowercase alphabet of column data mark show significant difference ( p<0.05), containing identical lowercase or without letter representation difference not significantly ( p>0.05).Lower same
Result shows, compares with control group, and the group weanling pig of adding the feed additive for weaning piglet of embodiment gained has higher average daily gain and daily ingestion amount, and wherein the average daily gain of T1 processed group and feed intake increase are significantly, with control group significant difference.Meanwhile, compared with control group, the feed-weight ratio of processed group also decreases.Illustrate, the feed additive for weaning piglet of gained of the present invention can improve the growth performance of weanling pig, improves the digestion power of weanling pig, improves the utilization rate of feed to a certain extent.
The feed additive for weaning piglet of gained of the present invention is on the impact of weanling pig oxidation resistance
Choose the comparatively close weanling pig of parity, Confinement Time (21d wean) 120, be divided into 6 process (i.e. control groups at random, process 1 group (T1), process 2 groups (T2), process 3 groups (T3), process 4 groups (T4), process 5 groups (T5)), each process 4 repetition, often repeats 5 pigs, often repeats separated raising.Control group fed sucking pig material, 5 processed group add the obtained feed addictive of 5 embodiments respectively at sucking pig material respectively, and add in weanling pig feed according to corresponding additive capacity.All piglets let alone free choice feeding and drinking-water, and feed 29d.Any other medicines additive is no longer added in sucking pig material.
In 14d, 30d early morning, often repeat random selecting 2 pigs, jugular vein blood collection, 37 DEG C of standing 2h, 4 DEG C of 4h, centrifugal, centrifugal 8 min of 3500rpm, separate out serum ,-20 DEG C of preservations.Measure MDA, T-SOD, GSH-Px concentration in serum.Investigate the feed additive for weaning piglet of gained of the present invention to the impact of weanling pig oxidation resistance.It the results are shown in Table 3 and table 4.
Table 3 the 14th d weanling pig Serum antioxidant indices
Group SOD(U/ml) GSH-Px(U/ml) MDA(nmol/ml)
Control group 108.33±2.92b 333.63±39.78 5.40±0.20a
T1 126.52±5.56a 389.93±31.23 3.02±0.80c
T2 110.42±3.03b 408.30±32.31 4.26±0.44b
T3 108.27±5.77b 384.00±22.20 4.44±0.15b
T4 115.35±4.65b 385.56±28.95 4.17±0.23bc
T5 118.87±5.34b 359.11±37.85 3.95±0.35bc
Table 4 the 30th d weanling pig Serum antioxidant indices
Group SOD(U/ml) GSH-Px(U/ml) MDA(nmol/ml)
Control group 105.25±3.12b 522.11±35.79b 4.38±0.05a
T1 111.75±2.83a 637.89±42.11a 2.86±0.21c
T2 108.26±3.30ab 566.32±31.01ab 2.70±0.22c
T3 107.75±2.35ab 536.84±23.73b 2.73±0.27c
T4 109.75±2.19a 549.47±35.32ab 3.27±0.18b
T5 108.75±3.50ab 551.58±30.79ab 3.11±0.21bc
Result shows, compares with control group, and adding SOD and GSH-Px concentration in the group piglet serum of the feed additive for weaning piglet of embodiment of the present invention gained has and increase in various degree, and MDA concentration reduces.Illustrate and add the antioxygenic property that feed addictive of the present invention improves weanling pig in various degree.
The feed additive for weaning piglet of gained of the present invention is on the impact of weanling pig inflammatory factor
Choose the comparatively close weanling pig of parity, Confinement Time (21d wean) 120, be divided into 4 process (control group, processes 1 group, processes 2 groups, processes 3 groups) at random, each process 4 repetition, often repeat 5 pigs, often repeat separated raising.Control group fed sucking pig material, 5 processed group add the obtained feed addictive of 5 embodiments respectively at sucking pig material respectively, and add in weanling pig feed according to corresponding additive capacity.All piglets let alone free choice feeding and drinking-water, feed 29d.Any other medicines additive is no longer added in sucking pig material.
In 14d, 30d early morning, often repeat random selecting 2 pigs, jugular vein blood collection, 37 DEG C of standing 2h, 4 DEG C of 4h, centrifugal, centrifugal 8 min of 3500rpm, separate out serum ,-20 DEG C of preservations.Measure proinflammatory cytokine IL-1 β, IL-6, TNF-α and anti-inflammatory cytokines IL-4, IL-10, TGF-β concentration in serum.Investigate the feed additive for weaning piglet of gained of the present invention to the impact of weanling pig anti-inflammatory power.It the results are shown in Table 5 and table 6
Table 5 the 14th d weanling pig serum cytokines content (ng/L)
Group IL-1β IL-6 TNF-α IL-4 IL-10 TGF-β
Control group 2300±492a 51.43±5.15a 2260±30a 12.08±2.60c 58.51±8.36c 210.00±10.00b
T1 1033±152b 23.62±5.06c 1954±29c 19.25±0.66ab 64.71±2.94ab 236.67±10.41ab
T2 560±105c 29.76±5.27bc 2052±25b 21.25±3.31a 73.53±1.47a 248.33±20.21a
T3 783±208bc 45.71±4.71a 2122±14b 18.75±1.75ab 61.29±3.20b 225.00±15.50b
T4 750±125bc 35.17±3.76b 2068±17b 20.12±1.25a 60.20±4.27b 265±10.00a
T5 816±57b 30.57±2.65bc 1981±20c 23.78±2.21a 67.65±4.53ab 255.40±12.65a
Table 6 the 30th d weanling pig serum cytokines content (ng/L)
Group IL-1β IL-6 TNF-α IL-4 IL-10 TGF-β
Control group 2050±450a 23.33±5.36a 2145±44a 14.58±2.89b 58.65±6.30bc 238.33±5.77b
T1 1250±180b 14.29±3.78b 1939±11c 27.50±5.00a 71.76±3.54ab 295.37±15.65a
T2 766±104c 17.14±3.11ab 2029±10b 35.00±4.51a 75.51±3.83a 251.67±17.56b
T3 1100±180b 19.24±1.28ab 2023±16b 16.25±3.25b 63.35±1.94b 245.00±5.00b
T4 850±230bc 18.57±3.29ab 2050±14b 32.50±2.58a 65.34±3.24b 310.00±15.00a
T5 800±185bc 20.71±1.43a 1944±14c 30.00±4.50a 70.62±5.88ab 270.85±12.35a
Result shows, the feed additive for weaning piglet group of adding embodiment of the present invention gained is compared with control group, piglet improves anti-inflammatory cytokines IL-4 in serum, IL-10 and TGF-β concentration, and reduces proinflammatory cytokine IL-1 β, IL-6 and TNF-α concentration.Illustrate that the feed additive for weaning piglet of embodiment of the present invention gained can strengthen the anti-inflammatory power of weanling pig.
The feed additive for weaning piglet of gained of the present invention is on the impact of weanling pig immunity
Choose the comparatively close weanling pig of parity, Confinement Time (21d wean) 120, be divided into 4 process (control group, processes 1 group, processes 2 groups, processes 3 groups) at random, each process 4 repetition, often repeat 5 pigs, often repeat separated raising.Control group fed sucking pig material, 5 processed group add the obtained feed addictive of 5 embodiments respectively at sucking pig material respectively, and add in weanling pig feed according to corresponding additive capacity.All piglets let alone free choice feeding and drinking-water, and feed 29d.
In 14d, 30d early morning, often repeat random selecting 2 pigs, jugular vein blood collection, 37 DEG C of standing 2h, 4 DEG C of 4h, centrifugal, centrifugal 8 min of 3500rpm, separate out serum ,-20 DEG C of preservations.Measure IgA, IgG and IgM concentration in serum.Investigate the feed additive for weaning piglet of gained of the present invention to the impact of weanling pig immunity.It the results are shown in Table 7 and table 8.
Table 7 the 14th d weanling pig Immunoglobulins in Serum (g/L)
Group IgM IgG IgA
Control group 0.37±0.06c 2.30±0.14b 0.01±0.00b
T1 0.74±0.06a 2.63±0.16a 0.04±0.01a
T2 0.45±0.07bc 2.40±0.10ab 0.02±0.01ab
T3 0.71±0.09a 2.48±0.06ab 0.02±0.01ab
T4 0.50±0.02b 2.52±0.02ab 0.03±0.01ab
T5 0.51±0.03b 2.35±0.04b 0.03±0.01ab
Table 8 the 30th d weanling pig Immunoglobulins in Serum (g/L)
Group IgM IgG IgA
Control group 0.45±0.07b 2.03±0.14b 0.01±0.00b
T1 0.74±0.06a 2.84±0.07a 0.04±0.01a
T2 0.57±0.04ab 2.34±0.12b 0.03±0.01ab
T3 0.51±0.08ab 2.51±0.08ab 0.02±0.01ab
T4 0.52±0.03ab 2.54±0.09ab 0.04±0.01a
T5 0.55±0.04ab 2.40±0.06b 0.03±0.01ab
Result shows, the group piglet of adding the feed additive for weaning piglet of embodiment of the present invention gained is compared with control group, and piglet Immunoglobulin in Serum content all has raising in various degree.
Comprehensive above result of the test, add the feed additive for weaning piglet of gained of the present invention, Growth Performance of Weaning Piglets gets a promotion, the utilization rate of weanling pig to feed also improves, digestive system function improves, and spends the early weaning phase smoothly improve guarantee for piglet, enables weanling pig digestive system adapt to forage feed as early as possible, reduce the generation of disease of digestive system, reduce the raising difficulty of weanling pig.In addition, add the feed additive for weaning piglet of gained of the present invention, the oxidation resistance of weanling pig, anti-inflammatory power, immunity all have raising in various degree, enhance the immunity of weanling pig to disease, decrease the generation of various disease, save feeding cost.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. a feed additive for weaning piglet, is characterized in that, comprises following component: false Betel extract and carrier.
2. a kind of feed additive for weaning piglet according to claim 1, is characterized in that: described Jia Betel extract formulation, comprises component: Jia Betel extract 1-5 part of following parts by weight, carrier 1-5 part.
3. a kind of feed additive for weaning piglet according to claim 1 and 2, is characterized in that: described carrier is silica or calcium carbonate.
4. a kind of feed additive for weaning piglet according to claim 1 and 2, is characterized in that: described Jia Betel extract is made as dry in the shade Folium Piperis sarmentosi sheet supercritical carbon dioxide extraction method or soxhlet extraction and extracts and obtain Jia Betel extract.
5. the preparation method of feed additive for weaning piglet as described in any one of claim 1 to 5, comprises the following steps:
Get formula ratio Jia Betel extract and carrier, mix, obtain feed additive for weaning piglet of the present invention.
6. according to any one of claim 1-4, feed additive for weaning piglet improves the application on the feed of Growth Performance of Weaning Piglets in preparation.
7. the feed additive for weaning piglet according to any one of claim 1-4 improves the application on the feed of weanling pig immunity in preparation.
8. the feed additive for weaning piglet according to any one of claim 1-4 improves the application on the feed of weanling pig anti-inflammatory power in preparation.
9. the feed additive for weaning piglet according to any one of claim 1-4 improves the application on the feed of weanling pig oxidation resistance in preparation.
10. the application of the feed additive for weaning piglet according to any one of claim 7-9, is characterized in that: described feed additive for weaning piglet consumption is that per kilogram feed adds 100-200 mg.
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CN104873579A (en) * 2015-05-22 2015-09-02 中国热带农业科学院热带作物品种资源研究所 Application of piper sarmentosum roxb extract
CN107668348A (en) * 2017-10-12 2018-02-09 广州傲农生物科技有限公司 A kind of compound additive for improving intestine of young pigs health and preparation method and application

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