CN104586533B - Simple, the filtered inside and outside formula carbon monoxide poisoning device of experimental implementation - Google Patents
Simple, the filtered inside and outside formula carbon monoxide poisoning device of experimental implementation Download PDFInfo
- Publication number
- CN104586533B CN104586533B CN201510067576.4A CN201510067576A CN104586533B CN 104586533 B CN104586533 B CN 104586533B CN 201510067576 A CN201510067576 A CN 201510067576A CN 104586533 B CN104586533 B CN 104586533B
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- CN
- China
- Prior art keywords
- air inlet
- carbon monoxide
- bottle
- gas flow
- adjusting means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
- A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices
Abstract
The invention discloses a kind of experimental implementation simple, filtered inside and outside formula carbon monoxide poisoning device, comprise bottle, bottleneck, bottle is for having inner bag, the sandwich format of outer gallbladder, bottleneck installs bottle stopper additional, bottle stopper is provided with the escape pipe stretched in interior bottle, the bottom position of outer gallbladder arranges carbon monoxide air inlet pipe, carbon monoxide air inlet pipe arranges gas flow adjusting means, at the lower area of interlayer, be placed with diluted sodium hydroxide solution, and the liquid level of diluted sodium hydroxide solution is higher than the air inlet in carbon monoxide air inlet pipe outside gallbladder, on inner bag, higher than the liquid level position of diluted sodium hydroxide solution, offer multiple air inlet.The present invention is rational in infrastructure, functional and simple to operate.
Description
The application is the divisional application of application number 201410373044.9, applying date 2014.8.1, title " filtered inside and outside formula carbon monoxide poisoning device ".
Technical field
The present invention relates to a kind of in the lab for the experimental provision of Study Mouse CO toxic reaction, is a kind of filtered carbon monoxide poisoning device.
Background technology
At present in institution of higher learning and scientific research institution, the experimentation of many relevant specialities will carry out the poisoning experiment of CO.Especially the specialty such as medical science, pharmacy, preventive medicine, toxicology and environmental science, all needs to carry out a large amount of experimentatioies relevant to CO.The poisoning device of traditional CO generally adopted now, comprise air inlet pipe, two wide mouthed bottles, airway and escape pipes, experimental provision is loaded down with trivial details, and practical operation is inconvenient.
Summary of the invention
The object of the present invention is to provide a kind of rational in infrastructure, filtered inside and outside formula carbon monoxide poisoning device functional and simple to operate.
Technical solution of the present invention is:
A kind of filtered inside and outside formula carbon monoxide poisoning device, it is characterized in that: comprise bottle, bottleneck, bottle is for having inner bag, the sandwich format of outer gallbladder, bottleneck installs bottle stopper additional, bottle stopper is provided with the escape pipe stretched in interior bottle, the bottom position of outer gallbladder arranges carbon monoxide air inlet pipe, carbon monoxide air inlet pipe arranges gas flow adjusting means, at the lower area of interlayer, be placed with diluted sodium hydroxide solution, and the liquid level of diluted sodium hydroxide solution is higher than the air inlet in carbon monoxide air inlet pipe outside gallbladder, on inner bag, higher than the liquid level position of diluted sodium hydroxide solution, offer multiple air inlet.
The bottle base thickness degree of bottle is greater than the thickness at other positions of bottle.
Gas flow adjusting means is arranged on the position, front end of carbon monoxide air inlet pipe.
The present invention is rational in infrastructure, functional and simple to operate.Mouth cylindrical part is made up of bottleneck, bottle stopper and escape pipe, and escape pipe communicates with air, and the partial pressure of oxygen in bottle and the partial pressure of oxygen in air are balanced, thus eliminates the factor of partial pressure of inspired oxygen reduction, makes the anoxia of mice be cause by simple CO is poisoning.Body comprises outer gallbladder and narrow meshed inner bag, and the interlayer between inner-outer tube is equipped with dilute NaOH solution.One end of air inlet pipe is connected with the maker producing CO by actuator, and the other end of air inlet pipe communicates with the interlayer between inner-outer tube, and CO gas overflows from dilute NaOH solution, and the volatile ingredient that during CO produces, other is mingled with is as then soluble in water in formic acid
.cO enters inner bag by aperture, and inner bag is for placing animal.Bottom thickeies, and strengthens the stability of whole device.Actuator is used to control CO gas flow, and the bubble number by the CO overflowed in solution in digit's time carrys out quantitative gas flow.The rapid death preventing from CO gas from too much entering inner bag by regulating CO gas flow causing laboratory animal.This device is the entirety adopting integration, and operation is simple for specific experiment, and the laboratory being applicable to the colleges and universities, scientific research institution etc. of each related discipline professional field widely uses, and can significantly improve work efficiency.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the invention will be further described.
Fig. 1 is the structural representation of one embodiment of the invention.
Detailed description of the invention
A kind of filtered inside and outside formula carbon monoxide poisoning device, comprise bottle, bottleneck 3, bottle is for having inner bag 4, the sandwich format of outer gallbladder 5, bottleneck installs bottle stopper 2 additional, bottle stopper is provided with the escape pipe 1 stretched in interior bottle, the bottom position of outer gallbladder arranges carbon monoxide air inlet pipe 8, carbon monoxide air inlet pipe is arranged gas flow adjusting means 9, at the lower area of interlayer, be placed with diluted sodium hydroxide solution 6, and the liquid level of diluted sodium hydroxide solution is higher than the air inlet in carbon monoxide air inlet pipe outside gallbladder, on inner bag, higher than the liquid level position of diluted sodium hydroxide solution, offer multiple air inlet 10.
At the bottom of the bottle of bottle, 7 thickness are greater than the thickness at other positions of bottle.Gas flow adjusting means is arranged on the position, front end of carbon monoxide air inlet pipe.
Specific experiment process of the present invention is:
After various preparations before carrying out experiment, take out the poisoning device of CO cleaned, during operation, (1) first notes dilute NaOH solution.Open gas flow adjusting means 9, in the interlayer of inner-outer tube, injected the dilute NaOH solution (0.5mol/L) prepared in advance by gas flow adjusting means.(2) gas flow adjusting means switch is shut.(3) gas flow adjusting means is connected with the maker producing CO.(4) mice is placed.Open bottle stopper 2 and the mice weighing up body weight is put into inner bag 4.(5) produce CO, observe the CO toxic reaction of mice.Formic acid and concentrated sulphuric acid is added respectively in CO maker, while allowing both hybrid reactions generate CO, cover tightly bottle stopper 2, and slightly open gas flow adjusting means 9 switch, regulate throughput, count CO bubble number of overflowing from liquid per minute and carry out quantitative CO flow.Examine the CO toxic reaction process of record mice.The invention of this experimental provision is rational in infrastructure, and service behaviour is good, can observe the CO intoxication process of mice in detail.Compared with the poisoning device of the CO of traditional split, this kind of integrated poisoning apparatus structure of CO is compact, simple to operate, and scalable CO flow, is convenient to the CO toxic reaction examining mice.
Claims (1)
1. an experimental implementation is simple, filtered inside and outside formula carbon monoxide poisoning device, comprise bottle, bottleneck, bottle is for having inner bag, the sandwich format of outer gallbladder, bottleneck installs bottle stopper additional, bottle stopper is provided with the escape pipe stretched in interior bottle, it is characterized in that: the bottom position of outer gallbladder arranges carbon monoxide air inlet pipe, carbon monoxide air inlet pipe arranges gas flow adjusting means, at the lower area of interlayer, be placed with diluted sodium hydroxide solution, and the liquid level of diluted sodium hydroxide solution is higher than the air inlet in carbon monoxide air inlet pipe outside gallbladder, on inner bag, higher than the liquid level position of diluted sodium hydroxide solution, offer multiple air inlet,
Gas flow adjusting means is arranged on the position, front end of carbon monoxide air inlet pipe;
After various preparations before carrying out experiment, take out the poisoning device of CO cleaned, during operation, (1) first notes dilute NaOH solution: open gas flow adjusting means, is injected the dilute NaOH solution prepared in advance by gas flow adjusting means in interlayer; (2) gas flow adjusting means switch is shut; (3) gas flow adjusting means is connected with the maker producing CO; (4) mice is placed; Open bottle stopper and the mice weighing up body weight is put into inner bag; (5) produce CO, observe the CO toxic reaction of mice; In CO maker, add formic acid and concentrated sulphuric acid respectively, while allowing both hybrid reactions generate CO, cover tightly bottle stopper, and slightly open gas flow adjusting means switch, regulate throughput, count CO bubble number of overflowing from liquid per minute and carry out quantitative CO flow; Examine the CO toxic reaction process of record mice.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410373044.9A CN104127257B (en) | 2014-08-01 | 2014-08-01 | Filtered internal and external type carbon monoxide poisoning device |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410373044.9A Division CN104127257B (en) | 2014-08-01 | 2014-08-01 | Filtered internal and external type carbon monoxide poisoning device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104586533A CN104586533A (en) | 2015-05-06 |
| CN104586533B true CN104586533B (en) | 2016-04-27 |
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ID=51800292
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510067576.4A Expired - Fee Related CN104586533B (en) | 2014-08-01 | 2014-08-01 | Simple, the filtered inside and outside formula carbon monoxide poisoning device of experimental implementation |
| CN201410373044.9A Expired - Fee Related CN104127257B (en) | 2014-08-01 | 2014-08-01 | Filtered internal and external type carbon monoxide poisoning device |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410373044.9A Expired - Fee Related CN104127257B (en) | 2014-08-01 | 2014-08-01 | Filtered internal and external type carbon monoxide poisoning device |
Country Status (1)
| Country | Link |
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| CN (2) | CN104586533B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108420565B (en) * | 2018-02-13 | 2019-08-23 | 浙江大学 | A kind of CO sucking models Hypoxia bottle |
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| US4721060A (en) * | 1986-07-17 | 1988-01-26 | Battelle Memorial Institute | Nose-only exposure system |
| US4860741A (en) * | 1987-02-09 | 1989-08-29 | Research & Consulting Co. A.G. | Modular inhalation tower for laboratory animals |
| US5099792A (en) * | 1991-04-08 | 1992-03-31 | Battelle Memorial Institute | Interchangeable whole-body and nose-only exposure system |
| CN101803962A (en) * | 2010-04-23 | 2010-08-18 | 中国人民解放军军事医学科学院微生物流行病研究所 | Rodent oronasal suction dynamic exposing device |
| CN101959473A (en) * | 2008-02-29 | 2011-01-26 | 菲利普莫里斯生产公司 | Exposure apparatus |
| CN202110166U (en) * | 2011-05-26 | 2012-01-11 | 山西大学 | Dynamic toxicant exposure device for toxic gas |
| CN102389339A (en) * | 2011-07-06 | 2012-03-28 | 天津开发区合普工贸有限公司 | Only-nose inhaling poison exposure experimental equipment for rodent |
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| US7503323B2 (en) * | 2002-02-20 | 2009-03-17 | Xenogen Corporation | Multiple output anesthesia system |
| JP4999354B2 (en) * | 2006-05-02 | 2012-08-15 | 照男 小林 | Concentrated oxygen supply device for animal treatment and concentrated oxygen supply method for animal treatment |
| US20090223460A1 (en) * | 2008-03-10 | 2009-09-10 | Starr Life Sciences Corp. | Bioactive gas supply chamber for animal research such as hypoxia studies on non-anesthetized small animals with direct physiologic monitoring |
| CN201551934U (en) * | 2009-12-04 | 2010-08-18 | 秦建 | Small-sized air washing filter |
| CN203537922U (en) * | 2013-08-20 | 2014-04-16 | 山东省农业科学院农产品研究所 | Edible mushroom liquid fermentation tank |
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2014
- 2014-08-01 CN CN201510067576.4A patent/CN104586533B/en not_active Expired - Fee Related
- 2014-08-01 CN CN201410373044.9A patent/CN104127257B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4721060A (en) * | 1986-07-17 | 1988-01-26 | Battelle Memorial Institute | Nose-only exposure system |
| US4860741A (en) * | 1987-02-09 | 1989-08-29 | Research & Consulting Co. A.G. | Modular inhalation tower for laboratory animals |
| US5099792A (en) * | 1991-04-08 | 1992-03-31 | Battelle Memorial Institute | Interchangeable whole-body and nose-only exposure system |
| CN101959473A (en) * | 2008-02-29 | 2011-01-26 | 菲利普莫里斯生产公司 | Exposure apparatus |
| CN101803962A (en) * | 2010-04-23 | 2010-08-18 | 中国人民解放军军事医学科学院微生物流行病研究所 | Rodent oronasal suction dynamic exposing device |
| CN202110166U (en) * | 2011-05-26 | 2012-01-11 | 山西大学 | Dynamic toxicant exposure device for toxic gas |
| CN102389339A (en) * | 2011-07-06 | 2012-03-28 | 天津开发区合普工贸有限公司 | Only-nose inhaling poison exposure experimental equipment for rodent |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104586533A (en) | 2015-05-06 |
| CN104127257B (en) | 2015-04-15 |
| CN104127257A (en) | 2014-11-05 |
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