CN104127257A - Filtered internal and external type carbon monoxide poisoning device - Google Patents

Filtered internal and external type carbon monoxide poisoning device Download PDF

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Publication number
CN104127257A
CN104127257A CN201410373044.9A CN201410373044A CN104127257A CN 104127257 A CN104127257 A CN 104127257A CN 201410373044 A CN201410373044 A CN 201410373044A CN 104127257 A CN104127257 A CN 104127257A
Authority
CN
China
Prior art keywords
carbon monoxide
bottle
inlet pipe
air inlet
sodium hydroxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201410373044.9A
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Chinese (zh)
Other versions
CN104127257B (en
Inventor
刘霞
马红萍
吴扬
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nantong University
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Nantong University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nantong University filed Critical Nantong University
Priority to CN201510067576.4A priority Critical patent/CN104586533B/en
Priority to CN201410373044.9A priority patent/CN104127257B/en
Priority to CN201510074552.1A priority patent/CN104605959B/en
Publication of CN104127257A publication Critical patent/CN104127257A/en
Application granted granted Critical
Publication of CN104127257B publication Critical patent/CN104127257B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A61D7/04Devices for anaesthetising animals by gases or vapours; Inhaling devices

Abstract

The invention discloses a filtered internal and external type carbon monoxide poisoning device which comprises a bottle body and a bottle mouth. The bottle body is in an interlayer type with an inner container and an outer container, a bottle plug is additionally arranged on the bottle mouth, a gas outlet pipe stretching in the bottle body is arranged on the bottle plug, a carbon monoxide gas inlet pipe is arranged at the bottom of the outer container, a gas flow adjusting device is arranged on the carbon monoxide gas inlet pipe, dilute sodium hydroxide solutions are contained in the lower area of the interlayer, the liquid level of the dilute sodium hydroxide solutions is higher than a gas inlet, in the outer container, of the carbon monoxide gas inlet pipe, and a plurality of gas inlet holes are formed in the position, higher than the liquid level of the dilute sodium hydroxide solutions, on the inner container. The filtered internal and external type carbon monoxide poisoning device is reasonable in structure, good in performance and easy to operate.

Description

Filtered inside and outside formula carbon monoxide poisoning device
Technical field
The present invention relates to a kind of in laboratory the experimental provision for Study Mouse CO toxic reaction, be a kind of filtered carbon monoxide poisoning device.
Background technology
In institution of higher learning and scientific research institution, the experimentation of many relevant specialities will be carried out the poisoning experiment of CO at present.Especially the specialty such as medical science, pharmacy, preventive medicine, toxicology and environmental science, all needs to carry out a large amount of experimentatioies relevant to CO.The poisoning device of traditional CO generally adopting now, comprises air inlet pipe, two wide mouthed bottles, airway and escape pipes, and experimental provision is loaded down with trivial details, practical operation inconvenience.
Summary of the invention
The object of the present invention is to provide filtered inside and outside formula carbon monoxide poisoning device a kind of rational in infrastructure, functional and simple to operate.
Technical solution of the present invention is:
A kind of filtered inside and outside formula carbon monoxide poisoning device, it is characterized in that: comprise bottle, bottleneck, bottle is for having inner bag, the interlayer form of outer gallbladder, on bottleneck, install bottle stopper additional, bottle stopper is provided with the escape pipe stretching in interior bottle, the bottom position of outer gallbladder arranges carbon monoxide air inlet pipe, in carbon monoxide air inlet pipe, gas flow adjusting means is set, at the lower area of interlayer, be placed with diluted sodium hydroxide solution, and the liquid level of diluted sodium hydroxide solution is higher than the carbon monoxide air inlet pipe air inlet on gallbladder outside, on inner bag, higher than the liquid level position of diluted sodium hydroxide solution, offer multiple air inlets.
The bottle base thickness degree of bottle is greater than the thickness at other positions of bottle.
Gas flow adjusting means is arranged on the front end position of carbon monoxide air inlet pipe.
The present invention is rational in infrastructure, functional and simple to operate.Mouth cylindrical part is made up of bottleneck, bottle stopper and escape pipe, and escape pipe communicates with atmosphere, makes the partial pressure of oxygen balance in partial pressure of oxygen and the atmosphere in bottle, thereby has got rid of the factor that partial pressure of inspired oxygen reduces, and the anoxia that makes mice is to cause by simple CO is poisoning.Body comprises outer gallbladder and narrow meshed inner bag, and the interlayer between inner-outer tube is equipped with dilute NaOH solution.One end of air inlet pipe is connected with the maker of producing CO by actuator, and the interlayer between the other end and the inner-outer tube of air inlet pipe communicates, and CO gas overflows from dilute NaOH solution, and during CO produces, other volatile ingredient being mingled with is as soluble in water in formic acid .cO enters inner bag by aperture, and inner bag is used for placing animal.Bottom thickeies, and strengthens the stability of whole device.Actuator is for controlling CO gas flow, can carry out quantitative gas flow by the bubble number of the CO that overflows in solution in digit's time.By regulating CO gas flow to prevent that CO gas from too much entering the rapid death that inner bag causes laboratory animal.This device is to adopt integrated entirety, and operation is simple for specific experiment, and the laboratory that is applicable to colleges and universities, the scientific research institution etc. of each related discipline professional field is widely used, and can significantly improve work efficiency.
Brief description of the drawings
Below in conjunction with drawings and Examples, the invention will be further described.
Fig. 1 is the structural representation of one embodiment of the invention.
Detailed description of the invention
A kind of filtered inside and outside formula carbon monoxide poisoning device, comprise bottle, bottleneck 3, bottle is for having inner bag 4, the interlayer form of outer gallbladder 5, on bottleneck, install bottle stopper 2 additional, bottle stopper is provided with the escape pipe 1 stretching in interior bottle, the bottom position of outer gallbladder arranges carbon monoxide air inlet pipe 8, gas flow adjusting means 9 is set in carbon monoxide air inlet pipe, at the lower area of interlayer, be placed with diluted sodium hydroxide solution 6, and the liquid level of diluted sodium hydroxide solution is higher than the carbon monoxide air inlet pipe air inlet on gallbladder outside, on inner bag, higher than the liquid level position of diluted sodium hydroxide solution, offer multiple air inlets 10.
The bottle ends 7 thickness of bottle is greater than the thickness at other positions of bottle.Gas flow adjusting means is arranged on the front end position of carbon monoxide air inlet pipe.
Specific experiment process of the present invention is:
After the various preparations of carrying out before experiment, take out the poisoning device of clean CO, when operation, (1) first notes dilute NaOH solution.Open gas flow adjusting means 9, in the interlayer of inner-outer tube, inject the dilute NaOH solution (0.5mol/L) preparing in advance by gas flow adjusting means.(2) shut gas flow adjusting means switch.(3) gas flow adjusting means is connected with the maker of producing CO.(4) place mice.Open bottle stopper 2 mice that weighs up body weight is put into inner bag 4.(5) produce CO, observe the CO toxic reaction of mice.In CO maker, add respectively formic acid and concentrated sulphuric acid, when allowing both hybrid reactions generate CO, cover tightly bottle stopper 2, and slightly open gas flow adjusting means 9 switches, regulate throughput, count CO bubble number of overflowing per minute and carry out quantitative CO flow from liquid.Examine the CO toxic reaction process that records mice.The invention of this experimental provision is rational in infrastructure, and service behaviour is good, can observe in detail the poisoning process of CO of mice.Compared with the poisoning device of CO of traditional split, this kind of poisoning apparatus structure compactness of integrated CO, simple to operate, and scalable CO flow, be convenient to examine the CO toxic reaction of mice.

Claims (3)

1. a filtered inside and outside formula carbon monoxide poisoning device, it is characterized in that: comprise bottle, bottleneck, bottle is for having inner bag, the interlayer form of outer gallbladder, on bottleneck, install bottle stopper additional, bottle stopper is provided with the escape pipe stretching in interior bottle, the bottom position of outer gallbladder arranges carbon monoxide air inlet pipe, in carbon monoxide air inlet pipe, gas flow adjusting means is set, at the lower area of interlayer, be placed with diluted sodium hydroxide solution, and the liquid level of diluted sodium hydroxide solution is higher than the carbon monoxide air inlet pipe air inlet on gallbladder outside, on inner bag, higher than the liquid level position of diluted sodium hydroxide solution, offer multiple air inlets.
2. filtered inside and outside formula carbon monoxide poisoning device according to claim 1, is characterized in that: the bottle base thickness degree of bottle is greater than the thickness at other positions of bottle.
3. filtered inside and outside formula carbon monoxide poisoning device according to claim 1 and 2, is characterized in that: gas flow adjusting means is arranged on the front end position of carbon monoxide air inlet pipe.
CN201410373044.9A 2014-08-01 2014-08-01 Filtered internal and external type carbon monoxide poisoning device Expired - Fee Related CN104127257B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201510067576.4A CN104586533B (en) 2014-08-01 2014-08-01 Simple, the filtered inside and outside formula carbon monoxide poisoning device of experimental implementation
CN201410373044.9A CN104127257B (en) 2014-08-01 2014-08-01 Filtered internal and external type carbon monoxide poisoning device
CN201510074552.1A CN104605959B (en) 2014-08-01 2014-08-01 Filtered inside and outside formula carbon monoxide poisoning device rational in infrastructure

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410373044.9A CN104127257B (en) 2014-08-01 2014-08-01 Filtered internal and external type carbon monoxide poisoning device

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201510067576.4A Division CN104586533B (en) 2014-08-01 2014-08-01 Simple, the filtered inside and outside formula carbon monoxide poisoning device of experimental implementation
CN201510074552.1A Division CN104605959B (en) 2014-08-01 2014-08-01 Filtered inside and outside formula carbon monoxide poisoning device rational in infrastructure

Publications (2)

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CN104127257A true CN104127257A (en) 2014-11-05
CN104127257B CN104127257B (en) 2015-04-15

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CN201410373044.9A Expired - Fee Related CN104127257B (en) 2014-08-01 2014-08-01 Filtered internal and external type carbon monoxide poisoning device
CN201510067576.4A Expired - Fee Related CN104586533B (en) 2014-08-01 2014-08-01 Simple, the filtered inside and outside formula carbon monoxide poisoning device of experimental implementation

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108420565B (en) * 2018-02-13 2019-08-23 浙江大学 A kind of CO sucking models Hypoxia bottle

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US5099792A (en) * 1991-04-08 1992-03-31 Battelle Memorial Institute Interchangeable whole-body and nose-only exposure system
WO2003070308A1 (en) * 2002-02-20 2003-08-28 Xenogen Corporation Multiple output anesthesia system
JP2007296231A (en) * 2006-05-02 2007-11-15 Teruo Kobayashi Apparatus and method for supplying concentrated oxygen for animal treatment
US20090223460A1 (en) * 2008-03-10 2009-09-10 Starr Life Sciences Corp. Bioactive gas supply chamber for animal research such as hypoxia studies on non-anesthetized small animals with direct physiologic monitoring
CN201551934U (en) * 2009-12-04 2010-08-18 秦建 Small-sized air washing filter
CN202110166U (en) * 2011-05-26 2012-01-11 山西大学 Dynamic toxicant exposure device for toxic gas
CN203537922U (en) * 2013-08-20 2014-04-16 山东省农业科学院农产品研究所 Edible mushroom liquid fermentation tank

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US4721060A (en) * 1986-07-17 1988-01-26 Battelle Memorial Institute Nose-only exposure system
CH670378A5 (en) * 1987-02-09 1989-06-15 Res And Consulting Company A G
EP2095791A1 (en) * 2008-02-29 2009-09-02 Philip Morris Products S.A. Exposure apparatus
CN101803962B (en) * 2010-04-23 2011-10-05 中国人民解放军军事医学科学院微生物流行病研究所 Rodent oronasal suction dynamic exposing device
CN102389339A (en) * 2011-07-06 2012-03-28 天津开发区合普工贸有限公司 Only-nose inhaling poison exposure experimental equipment for rodent

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099792A (en) * 1991-04-08 1992-03-31 Battelle Memorial Institute Interchangeable whole-body and nose-only exposure system
WO2003070308A1 (en) * 2002-02-20 2003-08-28 Xenogen Corporation Multiple output anesthesia system
JP2007296231A (en) * 2006-05-02 2007-11-15 Teruo Kobayashi Apparatus and method for supplying concentrated oxygen for animal treatment
US20090223460A1 (en) * 2008-03-10 2009-09-10 Starr Life Sciences Corp. Bioactive gas supply chamber for animal research such as hypoxia studies on non-anesthetized small animals with direct physiologic monitoring
CN201551934U (en) * 2009-12-04 2010-08-18 秦建 Small-sized air washing filter
CN202110166U (en) * 2011-05-26 2012-01-11 山西大学 Dynamic toxicant exposure device for toxic gas
CN203537922U (en) * 2013-08-20 2014-04-16 山东省农业科学院农产品研究所 Edible mushroom liquid fermentation tank

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Publication number Publication date
CN104586533A (en) 2015-05-06
CN104586533B (en) 2016-04-27
CN104127257B (en) 2015-04-15

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