CN104116573B - Up-and-down type filtered CO poisoning device - Google Patents
Up-and-down type filtered CO poisoning device Download PDFInfo
- Publication number
- CN104116573B CN104116573B CN201410383057.4A CN201410383057A CN104116573B CN 104116573 B CN104116573 B CN 104116573B CN 201410383057 A CN201410383057 A CN 201410383057A CN 104116573 B CN104116573 B CN 104116573B
- Authority
- CN
- China
- Prior art keywords
- bottle
- storehouse
- carbon monoxide
- inlet pipe
- gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
Abstract
The invention discloses an up-and-down type filtered CO poisoning device comprising a bottle, a bottle plug is additionally arranged at a bottle mouth of the bottle, the bottle plug is provided with a gas outlet pipe extending into an inner bottle, the bottle is divided into an upper bin and a lower bin through a partition layer, the lower bin is a liquid bin for containing reaction liquid, the upper bin is a space used for placement of laboratory mice, the partition layer is provided with a gas guide pipe used for introducing CO gas into the upper bin from the lower bin, the upper portion of the gas guide pipe protrudes out of the upper surface of the partition layer, the lower bin is connected with a CO gas inlet pipe, and the CO gas inlet pipe is provided with a gas flow adjusting device. The up-and-down type filtered CO poisoning device is reasonable in structure, good in performance and easy in operation.
Description
Technical field
The present invention relates to a kind of carbon monoxide poisoning device.
Background technology
At present in institution of higher learning and scientific research institution, the experimentation of many relevant specialities will carry out the poisoning experiment of CO.Especially the specialty such as medical science, pharmacy, preventive medicine, toxicology and environmental science, all needs to carry out a large amount of experimentatioies relevant to CO.The poisoning device of traditional CO generally adopted now, comprise air inlet pipe, two wide mouthed bottles, airway and escape pipes, experimental provision is loaded down with trivial details, and practical operation is inconvenient.
Summary of the invention
The object of the present invention is to provide a kind of filtered vertical type carbon monoxide poisoning device rational in infrastructure, functional and simple to operate.
Technical solution of the present invention is:
A kind of filtered vertical type carbon monoxide poisoning device, it is characterized in that: comprise bottle, the bottleneck of bottle is added with bottle stopper, bottle stopper is provided with the escape pipe stretched in interior bottle, bottle is separated into upper and lower two storehouses by interlayer, lower storehouse is the liquid storehouse of placing response liquid, upper storehouse is the space for placing experiment mice, interlayer is arranged CO gas is introduced upper storehouse by one airway from lower storehouse, the top of this airway protrudes from the upper surface of interlayer, be connected to the air inlet pipe passing into CO at Xia Cang position, carbon monoxide air inlet pipe arranges gas flow adjusting means.
The bottle base thickness degree of bottle is greater than the thickness at other positions of bottle.
Gas flow adjusting means is arranged on the position, front end of carbon monoxide air inlet pipe.
Apparatus of the present invention are poisoning devices of CO of a kind of integration, and it is made up of five parts, i.e. mouth cylindrical part, body, bottom, air inlet pipe and actuator.Mouth cylindrical part is made up of bottleneck, bottle stopper and escape pipe, and escape pipe communicates with air, and the partial pressure of oxygen in bottle and the partial pressure of oxygen in air are balanced, thus eliminates the factor of partial pressure of inspired oxygen reduction, makes the anoxia of mice be cause by simple CO is poisoning.Body comprises Shang Cang, lower storehouse and the interlayer up and down between storehouse.Upper storehouse is used to placement mice, and interlayer is with a short airway, and lower storehouse is for filling dilute NaOH solution.One end of air inlet pipe is connected with the maker producing CO by actuator, and the other end of air inlet pipe communicates with Xia Cang, and CO gas overflows from dilute NaOH solution, and the volatile ingredient that during CO produces, other is mingled with is as then soluble in water in formic acid.CO enters Shang Cang by the airway on interlayer.Because the density ratio air of CO is little, CO from the airway bottom upper storehouse out, mixes with the air in bottle better.Compared with CO in traditional device to be entered in bottle from above by airway in bottle stopper, this mode that CO enters from bottom bottle is more reasonable.In addition, airway exceeds interlayer plane, can prevent the Excreta of mice from leaking into Xia Cang.Bottom thickeies, and strengthens the stability of whole device.Actuator is used for control CO gas flow, and the bubble number by the CO overflowed in solution in digit's time carrys out quantitative gas flow.The rapid death preventing from CO gas from too much entering Shang Cang by regulating CO gas flow causing laboratory animal.This device is the entirety adopting integration, and operation is simple for specific experiment, and the laboratory being applicable to the colleges and universities, scientific research institution etc. of each related discipline professional field widely uses, and can significantly improve work efficiency.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the invention will be further described with experiment concrete steps.
Fig. 1 is structural representation of the present invention.
Detailed description of the invention
A kind of filtered vertical type carbon monoxide poisoning device, comprise bottle, the bottleneck 3 of bottle is added with bottle stopper 2, bottle stopper is provided with the escape pipe 1 stretched in interior bottle, bottle is separated into upper and lower two storehouses by interlayer 5, lower storehouse 6 is the liquid storehouse of placing response liquid (dilute NaOH solution) 11, upper storehouse 4 is the spaces for placing experiment mice, interlayer is arranged CO gas is introduced upper storehouse by one airway 10 from lower storehouse, the top of this airway protrudes from the upper surface of interlayer, the air inlet pipe 8 passing into CO is connected at Xia Cang position, carbon monoxide air inlet pipe is arranged gas flow adjusting means 9.
The bottle base thickness degree of bottle 7 is greater than the thickness at other positions of bottle.
Gas flow adjusting means (i.e. actuator) is arranged on the position, front end of carbon monoxide air inlet pipe.
Specific experiment process of the present invention is:
After various preparations before carrying out experiment, take out the poisoning device of CO cleaned, during operation, (1) first injects dilute NaOH solution.Open actuator 9, by injecting the dilute NaOH solution (0.5mol/L) prepared in advance in actuator and the downward storehouse 6 of air inlet pipe 8.Fluid level exceeds the opening of the enterprising trachea of bottle wall, lower than the lower surface of interlayer.(2) governor switch is shut.(3) actuator is connected with the maker producing CO.(4) mice is placed.Open bottle stopper 2 and the mice weighing up body weight is put into upper storehouse 4.(5) produce CO, observe the CO toxic reaction of mice.In CO maker, add formic acid and concentrated sulphuric acid respectively, while allowing both hybrid reactions generate CO, cover tightly bottle stopper 2, and slightly open actuator 9 switch, regulate throughput, the CO bubble number that digit overflows the time from liquid carrys out quantitative CO flow.The rapid death of laboratory animal is prevented from CO gas from too much entering causing by adjusting gas flow.Examine the CO toxic reaction process of record mice.The invention of this experimental provision is rational in infrastructure, and service behaviour is good, can observe the CO intoxication process of mice in detail.Compared with the poisoning device of the CO of traditional split, this kind of integrated poisoning apparatus structure of CO is compact, simple to operate.Because the density ratio air of CO is lower slightly, CO from the airway 10 bottom upper storehouse out, mixes with the air in bottle better, and, CO flow scalable.
Claims (3)
1. a filtered vertical type carbon monoxide poisoning device, it is characterized in that: comprise bottle, the bottleneck of bottle is added with bottle stopper, bottle stopper is provided with the escape pipe stretched in interior bottle, bottle is separated into upper and lower two storehouses by interlayer, lower storehouse is the liquid storehouse of placing response liquid, upper storehouse is the space for placing experiment mice, interlayer is arranged CO gas is introduced upper storehouse by one airway from lower storehouse, the top of this airway protrudes from the upper surface of interlayer, be connected to the air inlet pipe passing into CO at Xia Cang position, carbon monoxide air inlet pipe arranges gas flow adjusting means.
2. filtered vertical type carbon monoxide poisoning device according to claim 1, is characterized in that: the bottle base thickness degree of bottle is greater than the thickness at other positions of bottle.
3. filtered vertical type carbon monoxide poisoning device according to claim 1 and 2, is characterized in that: gas flow adjusting means is arranged on the position, front end of carbon monoxide air inlet pipe.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510274957.XA CN104873296B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
| CN201510274907.1A CN104873295B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
| CN201410383057.4A CN104116573B (en) | 2014-08-06 | 2014-08-06 | Up-and-down type filtered CO poisoning device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410383057.4A CN104116573B (en) | 2014-08-06 | 2014-08-06 | Up-and-down type filtered CO poisoning device |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510274957.XA Division CN104873296B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
| CN201510274907.1A Division CN104873295B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104116573A CN104116573A (en) | 2014-10-29 |
| CN104116573B true CN104116573B (en) | 2015-06-10 |
Family
ID=51762358
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510274907.1A Expired - Fee Related CN104873295B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
| CN201510274957.XA Expired - Fee Related CN104873296B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
| CN201410383057.4A Expired - Fee Related CN104116573B (en) | 2014-08-06 | 2014-08-06 | Up-and-down type filtered CO poisoning device |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510274907.1A Expired - Fee Related CN104873295B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
| CN201510274957.XA Expired - Fee Related CN104873296B (en) | 2014-08-06 | 2014-08-06 | Filtered vertical type carbon monoxide poisoning device |
Country Status (1)
| Country | Link |
|---|---|
| CN (3) | CN104873295B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873295B (en) * | 2014-08-06 | 2016-08-17 | 南通大学 | Filtered vertical type carbon monoxide poisoning device |
| CN108420565B (en) * | 2018-02-13 | 2019-08-23 | 浙江大学 | A kind of CO sucking models Hypoxia bottle |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137938A (en) * | 1995-04-30 | 1996-12-18 | 沙同家 | Gas purifier |
| CN2803309Y (en) * | 2005-07-19 | 2006-08-09 | 范维林 | Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device |
| JP2007296231A (en) * | 2006-05-02 | 2007-11-15 | Teruo Kobayashi | Apparatus and method for supplying concentrated oxygen for animal treatment |
| CN202110166U (en) * | 2011-05-26 | 2012-01-11 | 山西大学 | Dynamic toxicant exposure device for toxic gas |
| CN102389339A (en) * | 2011-07-06 | 2012-03-28 | 天津开发区合普工贸有限公司 | Only-nose inhaling poison exposure experimental equipment for rodent |
| CN203400145U (en) * | 2013-07-11 | 2014-01-22 | 河南大学淮河医院 | Device used for detecting oxygen consumption of animals |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010002331A1 (en) * | 2008-07-04 | 2010-01-07 | Astrazeneca Ab | Apparatus and method for exposing laboratory animals to a test substance |
| CN102053148A (en) * | 2009-10-29 | 2011-05-11 | 上海医药工业研究院 | Method for detecting exposure toxicity of nanoparticles and toxicant exposure cabinet used thereby |
| CN101889908B (en) * | 2010-07-06 | 2011-10-05 | 首都医科大学附属北京朝阳医院 | Gas atomization toxicant exposure box |
| CN102172336B (en) * | 2011-03-11 | 2013-04-03 | 山西农业大学 | Simple dynamic sulfur dioxide gas toxicant exposure experimental device |
| CN104873295B (en) * | 2014-08-06 | 2016-08-17 | 南通大学 | Filtered vertical type carbon monoxide poisoning device |
-
2014
- 2014-08-06 CN CN201510274907.1A patent/CN104873295B/en not_active Expired - Fee Related
- 2014-08-06 CN CN201510274957.XA patent/CN104873296B/en not_active Expired - Fee Related
- 2014-08-06 CN CN201410383057.4A patent/CN104116573B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137938A (en) * | 1995-04-30 | 1996-12-18 | 沙同家 | Gas purifier |
| CN2803309Y (en) * | 2005-07-19 | 2006-08-09 | 范维林 | Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device |
| JP2007296231A (en) * | 2006-05-02 | 2007-11-15 | Teruo Kobayashi | Apparatus and method for supplying concentrated oxygen for animal treatment |
| CN202110166U (en) * | 2011-05-26 | 2012-01-11 | 山西大学 | Dynamic toxicant exposure device for toxic gas |
| CN102389339A (en) * | 2011-07-06 | 2012-03-28 | 天津开发区合普工贸有限公司 | Only-nose inhaling poison exposure experimental equipment for rodent |
| CN203400145U (en) * | 2013-07-11 | 2014-01-22 | 河南大学淮河医院 | Device used for detecting oxygen consumption of animals |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104873295A (en) | 2015-09-02 |
| CN104873295B (en) | 2016-08-17 |
| CN104116573A (en) | 2014-10-29 |
| CN104873296A (en) | 2015-09-02 |
| CN104873296B (en) | 2016-09-28 |
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Granted publication date: 20150610 Termination date: 20160806 |