CN104585742A - A compound cordyceps sinensis oil soft capsule production method - Google Patents

A compound cordyceps sinensis oil soft capsule production method Download PDF

Info

Publication number
CN104585742A
CN104585742A CN201310533722.9A CN201310533722A CN104585742A CN 104585742 A CN104585742 A CN 104585742A CN 201310533722 A CN201310533722 A CN 201310533722A CN 104585742 A CN104585742 A CN 104585742A
Authority
CN
China
Prior art keywords
oil
caterpillar fungus
chinese caterpillar
production method
cordyceps sinensis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310533722.9A
Other languages
Chinese (zh)
Inventor
陈顺志
王林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JIANGSU XUEFU BIOLOGICAL ENGINEERING Co Ltd
Original Assignee
JIANGSU XUEFU BIOLOGICAL ENGINEERING Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JIANGSU XUEFU BIOLOGICAL ENGINEERING Co Ltd filed Critical JIANGSU XUEFU BIOLOGICAL ENGINEERING Co Ltd
Priority to CN201310533722.9A priority Critical patent/CN104585742A/en
Publication of CN104585742A publication Critical patent/CN104585742A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention discloses a compound cordyceps sinensis oil soft capsule production method which preferably selects cordyceps sinensis oil, Chinese wolfberry oil, safflower oil and olive oil with efficacies of lowering blood fat, beatifying features and protecting skins, selects oil components extracted from pure natural ingredients and has no side effects to human body. The cordyceps sinensis oil soft capsule has efficacies of effectively lowering blood fat, beatifying features and protecting skins by a scientific and reasonable compatibility of medicines.

Description

A kind of production method of compound Chinese caterpillar fungus fat capsule
Technical field
The present invention relates to a kind of production method of compound Chinese caterpillar fungus fat capsule, belong to food processing technology field, particularly health food processing technology.
Background technology
Hyperlipemia refers to a kind of disease disease that the lipid compositions such as cholesterol, triglyceride, phosphatide and not esterified resin acid in blood plasma increase.The reason of Hyperlipemia is that feed is fatty and cholesterol food too much, has relation with inherent cause etc. simultaneously." fat " in blood plasma mainly cholesterol and triglycerides, they are non-singleton also, but transported with the form of apolipoprotein, apolipoprotein mainly includes chylomicron (CM), VLDL (VLDL), IDL (IDL), low-density lipoprotein (LDL) and HDL (HDL) five kinds.Hyperlipemia is the hazards of systemic atherosclerosis, and as easily suffered from coronary heart disease, cerebrovascular sclerosis, peripheral angiopathy etc., sporter's hyperlipemia is as complicated hypertension less, diabetes, or has coronary heart disease, fat, cerebral apoplexy family history, and danger can increase 1-5 doubly.There are some researches prove, hyperlipemia, blood lipid level declines 1%, and the death rate of cardiovascular and cerebrovascular disease can decline 2%, and therefore, reducing blood lipid level is the important of prevention and therapy cardiovascular and cerebrovascular disease and effective means.
Current blood lipid-lowering medicine is wide in variety, effect is different, its mechanism of action is generally a certain or several link in interference Regulating Lipid Metabolism, as reduced decomposition and the excretion of lipid absorption or acceleration lipid, synthesis or the prevention lipoprotein of interference liver lipoprotein are conveyed into blood plasma in liver, increase the speed etc. that lipoprotein is removed from serum.Conventional Chinese medicine has Effects of Xuezhikang etc.Western medicine Statins, fibrate are remarkable to the comparitive study of the symptoms such as high fat of blood, but Western medicine, while reducing blood lipid, can cause blood sugar to raise, feel sick, the reaction such as diarrhoea and hepatic disorder at present.
Along with social development, the raising of people's living standard.At present, skin maintenance has become a kind of fashion, is subject to the favor of more and more people.But current skin protection cosmetics market management is more chaotic, the lead contained in many cosmetics, mercury, the harmful substance severe overweight such as female, directly affects the healthy of consumer.In addition, manufacturer is in order to ensure skin protection cosmetics unlikely inefficacy within the shelf-life of regulation, and usually can add a certain amount of anticorrisive agent, antiseptic in skin protection cosmetics, the nutritions such as its so-called VC, VE in fact all can not ensure its content.
At present, there are the cosmetics of some Chinese herbal and crude drugs preparationses to be developed application, are subject to the favor of more and more people, attention.The Multifunctional effect of tcm product is can not when with the cosmetics of chemical synthesis.But in the process of manufacture of these products, still be unable to do without some chemical substances, as emulsifying agent, anticorrisive agent, antiseptic etc., this kind of cosmetics effect health and beauty Long-Time Service to the skin of people and body generation infringement to a certain degree, can be caused ill effect.
Cordceps militaris is a kind of nutritious medical, edible fungi, Cordceps militaris is Clavicipitaceae fungi, it contains the multiple nutrients materials such as polysaccharide, PEARLITOL 25C, Fructus Hordei Germinatus sterol, several amino acids and trace element, recent studies have found that, Cordceps militaris is also containing bioactivators such as adenosine class, polysaccharide, alkaloids, cyclic peptide class, enzymes, and imparting Cordceps militaris is antibacterial, antitumor, radioresistance, anti-ageing multiple medical health care function of waiting for a long time.
The Chinese caterpillar fungus oil extracted from Cordyceps sinensis fungus, containing multiple nutrients material, as each seed amino acid, vitamin, nicotinic acid, nucleosides and many etc., has the effects such as health care, beauty and skin care and medical treatment.Due to the These characteristics that Chinese caterpillar fungus oil possesses, and higher raw material or the additive being used as food, medicine and cosmetics of security.
Matrimony vine seed is the seed of matrimony vine, include boxthorn root, leaf, fruit whole nutrition elite, have breed life grow, growth enrich bioactivator.Through scientific research, Lycium-seed-oil, except containing except linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, vitamin E, selenium, also contains the nutritional labelings such as multiple unrighted acid, trace element, bioactivator, EGF, SOD, beta carotene.There is the health-care effects such as antifatigue, adjusting blood lipid, liver-nourishing and eyesight-improving, raising immunity, beautifying face and moistering lotion, be famous and precious health care's treasure, often take delaying sanility, reach the health effect of promoting longevity.Containing abundant unrighted acid in Lycium-seed-oil, the content that effectively can reduce low-density lipoprotein in blood, improve HDL, significantly reduce triglycerides in blood, thus reach the effect reducing blood fat; Meanwhile, there is the effect obviously reducing total cholesterol level in blood, have well prevention and opsonic action to the disease of the cardiovascular and cerebrovascular such as hypertension, coronary heart disease that high fat of blood causes.Containing SOD and VE in Lycium-seed-oil, can eliminate the damage of superoxide radical to Skin Cell, improve the ability that skin absorption oxygen divides, delay skin aging, has the effect of beautifying face and moistering lotion.
Olive oil has the history of several thousand in Mediterranean country, and be described as " liquid golden " in west, " vegetable oil queen ", " Mediterranean sweet dew ", reason is just its splendid natural health effect, beauty functions and desirable cooking use.Olive oil can prevent artery sclerosis and atherosclerotic syndromes, hypertension, heart disease, heart failure, kidney failure, cerebral hemorrhage.A Erte Meath doctor Xi Mopulesi show " Europe miaow gal is healthy. simple longevity plan " mention ω-6 aliphatic acid in edible oil in a book and can make arterial contraction, thus force heart overload work, cause hypertension.And the omega-fatty acid in olive oil can increase the amount of this important chemical substance of nitrogen oxide, can relax your artery, thus prevent the arterial injury because hypertension causes.Omega-fatty acid can also prevent the formation of clot from two aspects in addition.First, it can reduce hematoblastic stickiness, allows blood platelet and fibrinogen not easily be intertwined; Secondly, omega-fatty acid can reduce fibrinogenic amount, also just greatly reduces thrombotic probability.Olive oil is rich in the squalene splendid with skin affinity and essential fatty acid, absorbs rapidly, effectively keeps skin elasticity with moist; Monounsaturated fatty acids contained abundant in olive oil and vitamin E, K, A, D etc. and phenols polyphenoils, facial wrinkles can be eliminated, prevent skin aging, there is the effect such as skin or hair care and control hand and foot from chapping, be the cosmetics and skincare product that can " eat ", smear skin with olive oil in addition and can resist ultraviolet and prevent cutaneum carcinoma.
Safflower oil is the high-quality kardiseed selecting Xinjiang to abound with is raw material, utilize current advanced technology and equipment, form through science processing refining, maintain original nutrition, be rich in natural VE, shelf-stable, not easily become sour, content of polyunsaturated fatty acid more than 90%, wherein linoleic acid content is up to 83%, rank first in the world, digestibility is 99% higher than all edible oil, not containing cholesterol, not containing any additive and anticorrisive agent, complete and meet " pollution-free food " standard.Safflower oil is the moisturizing grease of the heavier supply skin of a kind of feel and hair nutrition, the care human skin that it can double, increase the autgmentability of oil content on skin and cut skinfeel, also can be used on the microcirculation of the capillary among massage oil (cream frost) under skin expansion simultaneously, increase gloss and the elasticity of skin.Its light weak color and extremely low smell, the sense of taste are the optimum feed stock that can be used in massage oil, sesame oil base oil.The natural safflower composition of safflower oil is easy to attract, and strong skin effect is played in the metabolism increasing skin.
Along with the raising of living standards of the people, the expanding day of hyperglycaemia, people with hyperlipidemia, and the diabetes caused by hyperglycaemia, high fat of blood, blood circulation system disease is also increasing to human health risk.Due to the development of economic society, pollution in living environment is also more and more serious, along with the lifting of people's self health consciousness and aesthetic standards, the health food existing market possessing simultaneously effective reducing blood lipid and beautifying skin-protection function have not been reported, health food existing market with hypolipemic function and beauty and skin care also increases gradually, but works mainly with the form of one pack system or single effect greatly, acts synergistically poor, effect is not obvious, still can not meet the needs in market.Market proves, people to successful, the reducing blood lipid of complete function and to possess beauty and skin care health food demand very large simultaneously.Up to now, any report about health food of the present invention is not also found.The present inventor through repeatedly studying, and by the checking repeatedly of animal and clinical testing, finally have found the composition simultaneously possessing reducing blood lipid and beautifying skin-protection function better effects if, thus completes health food of the present invention.
Summary of the invention
For appeal problem, the object of this invention is to provide a kind of production method of compound Chinese caterpillar fungus fat capsule, preferably possess Chinese caterpillar fungus oil, Lycium-seed-oil, safflower oil, the olive oil of reducing blood lipid and beauty and skin care effect simultaneously, select the oil components that pure natural component is extracted, without any side effects to human body, beneficial effect of the present invention is, by scientific and reasonable compatibility, to reach effect of effective reducing blood lipid and beauty and skin care.
For achieving the above object, the technical solution used in the present invention is as follows:
A production method for compound Chinese caterpillar fungus fat capsule, comprises following component and weight proportion: Chinese caterpillar fungus oil 40 ~ 80mg, Lycium-seed-oil 30 ~ 50mg, safflower oil 20 ~ 30mg, beeswax 10 ~ 15mg, olive oil 380 ~ 440mg.
The optimum weight proportioning that 500mg/ grain soft capsule made by the various raw material of the present invention is: Chinese caterpillar fungus oil 50mg, Lycium-seed-oil 35mg, safflower oil E20mg, beeswax 10mg, olive oil 385mg.
The optimum weight proportioning that 600mg/ grain soft capsule made by the various raw material of the present invention is: Chinese caterpillar fungus oil 75mg, Lycium-seed-oil 50mg, safflower oil E26mg, beeswax 15mg, olive oil 434mg.
A production method for compound Chinese caterpillar fungus fat capsule, its step is as follows:
(1) Cordceps militaris obtains Chinese caterpillar fungus oil after the grease paste of supercritical carbon dioxide extracting is concentrated;
(2) by Chinese caterpillar fungus oil, Lycium-seed-oil, safflower oil, olive oil according to their weight ratio, be mixed to get composition, capsule machine be processed into soft capsule;
(3) under gmp conditions through sterilization, packaging, check, dispatch from the factory.
In compound Chinese caterpillar fungus fat capsule of the present invention, effective active composition comprises the various bioactivators such as cordycepin, cordycepic acid, Cordyceps sinensis polysaccharide, superoxide dismutase, omega-fatty acid, ω-6 aliphatic acid, unrighted acid.Cordycepin, i.e. 3'-Deoxyadenosine, similar with gland glycoside action, be a kind of nucleosides material with antibacterial activity, have very strong inhibitory action to core poly A polymerase, there is antiviral, antibacterial activity.Cordycepic acid, i.e. sweet mellow wine, can suppress the growth of various germ, promotes the metabolism of body.Superoxide dismutase is a kind of very important antioxidase, and it can help, and body is interior eliminates too much free radical, avoids cell to be subject to oxidation, aging or destruction, also waits suppression virus, strengthens immunologic function.Cordyceps sinensis polysaccharide has immunocompetence, can obviously strengthen body fluid and cellular immune function, the generation of enhancing antibody and interferon or antigen precursor reactant, the unrighted acids such as omega-fatty acid, ω-6 aliphatic acid obviously can reduce serum total cholesterol (TC), triglycerides (TG), low-density lipoprotein and extra-low density albumen, the effect of increasing serum HDL.
Compared with prior art, tool of the present invention has the following advantages:
(1) be a kind of special nourishing capsule, can play effectively reduce blood fat and there is moisturizing, go wrinkle, anti-inflammatory, brighten, the effect of ecchymose removing, toxin-expelling and face nourishing;
(2) technique is simple, easily realizes industrialization, and the Chinese caterpillar fungus oil transparency that supercritical technology extracts is high, safe heavy metal free and dissolvent residual;
(3) long shelf-life of product, stable components, taking convenience, has feasibility, also containing the trace element that the human bodies such as vitamin E are necessary, has the health-care effect promoting immunity of organisms.
(4) this formula combination is novel unique, and rest on a scientific basis original creation, effectively improves functional component effect, and to act on be comprehensive, not only effectively can reduce blood fat but also can play the effect of beauty and skin care.
Effect of the present invention is: the oil components reasonable compatibility simultaneously being possessed reducing blood lipid and beautifying skin-protection function by creationary use four kinds, utilize the Chinese caterpillar fungus oil component in the current extraction of supercritical carbon dioxide extraction method the most safely and efficiently Cordceps militaris, coordinate the oil components of three kinds of natural plants safflowers, olive, matrimony vine, be made into compound capsules product.There is the advantages such as production cost is low, technique is simple, the scope of application is wide, safe and efficient.
Detailed description of the invention
Embodiment 1:
The present embodiment compound Chinese caterpillar fungus fat capsule comprises following component and weight proportion: Chinese caterpillar fungus oil 50mg, Lycium-seed-oil 35mg, safflower oil 20mg, beeswax 10mg, olive oil 385mg.
1, Cordceps militaris obtains Chinese caterpillar fungus oil after the grease paste of supercritical carbon dioxide extracting is concentrated;
2, appeal weight ratio is the raw material in every 0.5g capsule, produces 10,000, just needs to be multiplied by 10,000 times.Add beeswax, olive wet goods fully mixes.
3, according to their weight ratio, mix, sieving obtains composition, on capsule machine, be processed into compound Chinese caterpillar fungus fat capsule under gmp conditions, can individual packaging, also can 6-12 grain/plate packaging.Through sterilization, packaging, check, dispatch from the factory.
Embodiment 2:
The present embodiment compound Chinese caterpillar fungus fat capsule comprises following component and weight proportion: Chinese caterpillar fungus oil 75mg, Lycium-seed-oil 50mg, safflower oil E26mg, beeswax 15mg, olive oil 434mg.
1, Cordceps militaris obtains Chinese caterpillar fungus oil after the grease paste of supercritical carbon dioxide extracting is concentrated;
2, appeal weight ratio is the raw material in every 0.6g capsule, produces 20,000, just needs to be multiplied by 20,000 times.Add beeswax, olive wet goods fully mixes.
3, according to their weight ratio, mix, sieving obtains composition, on capsule machine, be processed into compound Chinese caterpillar fungus fat capsule under gmp conditions, can individual packaging, also can 6-12 grain/plate packaging.Through sterilization, packaging, check, dispatch from the factory.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from Spirit Essence of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included in protection scope of the present invention.

Claims (4)

1. a production method for compound Chinese caterpillar fungus fat capsule, is characterized in that, comprises following component and weight proportion: Chinese caterpillar fungus oil 40 ~ 80mg, Lycium-seed-oil 30 ~ 50mg, safflower oil 20 ~ 30mg, beeswax 10 ~ 15mg, olive oil 380 ~ 440mg; According to their weight ratio, be mixed to get composition, capsule machine is processed into soft capsule; Under gmp conditions through sterilization, packaging, check, dispatch from the factory.
2. the production method of a kind of compound Chinese caterpillar fungus fat capsule according to claim 1, is characterized in that, comprise following component and weight proportion: Chinese caterpillar fungus oil 50mg, Lycium-seed-oil 35mg, safflower oil 20mg, beeswax 10mg, olive oil 385mg.
3. the production method of a kind of compound Chinese caterpillar fungus fat capsule according to claim 1, is characterized in that, comprise following component and weight proportion: Chinese caterpillar fungus oil 75mg, Lycium-seed-oil 50mg, safflower oil 26mg, beeswax 15mg, olive oil 434mg.
4. the production method of a kind of compound Chinese caterpillar fungus fat capsule according to claim 1, is characterized in that: Cordceps militaris obtains Chinese caterpillar fungus oil after the grease paste of supercritical carbon dioxide extracting is concentrated.
CN201310533722.9A 2013-10-31 2013-10-31 A compound cordyceps sinensis oil soft capsule production method Pending CN104585742A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310533722.9A CN104585742A (en) 2013-10-31 2013-10-31 A compound cordyceps sinensis oil soft capsule production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310533722.9A CN104585742A (en) 2013-10-31 2013-10-31 A compound cordyceps sinensis oil soft capsule production method

Publications (1)

Publication Number Publication Date
CN104585742A true CN104585742A (en) 2015-05-06

Family

ID=53112077

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310533722.9A Pending CN104585742A (en) 2013-10-31 2013-10-31 A compound cordyceps sinensis oil soft capsule production method

Country Status (1)

Country Link
CN (1) CN104585742A (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010046523A1 (en) * 2000-02-25 2001-11-29 Thomas Newmark Ginger-based herbal composition for promoting health and methods of using same
CN1347732A (en) * 2001-09-28 2002-05-08 陈顺志 Supercritical extraction process of producing cordyceps oil
CN1814040A (en) * 2005-12-02 2006-08-09 杨文龙 Compound liquid capsule of Chinese caterpillar fungus, preparing method and quality control method
CN1839711A (en) * 2005-03-31 2006-10-04 陈顺志 Production method of Chinese caterpillar fungus soft capsule
CN101045069A (en) * 2007-04-10 2007-10-03 深圳市中科海外科技有限公司 Method for extracting caterpillar fungus oil by using supercritical fluid of carbon dioxide
CN101406492A (en) * 2008-11-26 2009-04-15 吉林大学 Compound Cordyceps sinensis oil soft capsule and preparation technique
CN102626425A (en) * 2012-05-09 2012-08-08 马建中 Cordyceps sinensis powder soft capsule and preparation method thereof
CN103211149A (en) * 2013-04-22 2013-07-24 重庆阿尔康生物工程有限公司 Perilla composite capsule and preparation method thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010046523A1 (en) * 2000-02-25 2001-11-29 Thomas Newmark Ginger-based herbal composition for promoting health and methods of using same
CN1347732A (en) * 2001-09-28 2002-05-08 陈顺志 Supercritical extraction process of producing cordyceps oil
CN1839711A (en) * 2005-03-31 2006-10-04 陈顺志 Production method of Chinese caterpillar fungus soft capsule
CN1814040A (en) * 2005-12-02 2006-08-09 杨文龙 Compound liquid capsule of Chinese caterpillar fungus, preparing method and quality control method
CN101045069A (en) * 2007-04-10 2007-10-03 深圳市中科海外科技有限公司 Method for extracting caterpillar fungus oil by using supercritical fluid of carbon dioxide
CN101406492A (en) * 2008-11-26 2009-04-15 吉林大学 Compound Cordyceps sinensis oil soft capsule and preparation technique
CN102626425A (en) * 2012-05-09 2012-08-08 马建中 Cordyceps sinensis powder soft capsule and preparation method thereof
CN103211149A (en) * 2013-04-22 2013-07-24 重庆阿尔康生物工程有限公司 Perilla composite capsule and preparation method thereof

Similar Documents

Publication Publication Date Title
KR101373636B1 (en) Composition for improving condition of skin and scalp containing fermented extracts of herb mixture
Rafalska et al. Sea buckthorn (Hippophae rhamnoides L.) as a plant for universal application
CN103704816A (en) Hawthorn fruit vinegar and preparation method thereof
KR101186107B1 (en) A beverage comprising extract of hericium erinaceus and tremella fuciformis, and method for manufacturing thereof
CN101564180B (en) Walnut total nutriment and soft capsule and health products containing same
CN101791123B (en) Health care product abundant in vitamin B and vitamin C and preparation method thereof
CN106473114A (en) A kind of anti-apolexis composition
KR20090099110A (en) Functional cream including nano silver
KR101257435B1 (en) The cosmetic composition for alleviating atopy and contact dermatitis containing sage, Melissa officinalis, Gelidium amansii and Allium cepa
CN101433241A (en) Formula bovine colostrum
CN101632449A (en) Complex substance containing royal jelly and seabuckthorn oil
KR101835799B1 (en) A cosmetic composition for manufacturing by the using of propolis, and the cosmetic manufactured by the composition
CN107836533A (en) It is a kind of can external application beauty care edible purple perilla seed essential oil
CN101669640A (en) Method for preparing health-care food by using ginkgo biloba extract (GBE) and bee pollen
CN104585742A (en) A compound cordyceps sinensis oil soft capsule production method
Grad et al. Generalized yellow skin caused by high intake of sea buckthorn
Lee Essent ial Fat ty Acids
STAN et al. JUJUBE PROCESSING: METHODS, PRODUCTS AND NUTRACEUTICAL VALUE.
CN105901170A (en) Stomach-strengthening antioxidant sesame oil and a preparing method thereof
KR102095620B1 (en) Food Additive and Natural Functional Food
CN115414433B (en) Vegetable oil compound soft capsule with health care effect and preparation method thereof
Soliboeva Functional food products a promising direction of new innovative technologies in dietary
KR20150023132A (en) Composit for improving atopic dermatitis
KR20110008978A (en) Soap using jujube tree leaf
Rethinam Health and nutritional aspects of coconut oil

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
DD01 Delivery of document by public notice

Addressee: Jiangsu Xuefu Biological Engineering Co., Ltd.

Document name: Notification of Publication and of Entering the Substantive Examination Stage of the Application for Invention

DD01 Delivery of document by public notice

Addressee: Jiangsu Xuefu Biological Engineering Co., Ltd.

Document name: the First Notification of an Office Action

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150506