CN104548044A - Externally-applied medicine for treating prickly heat and preparation method thereof - Google Patents

Externally-applied medicine for treating prickly heat and preparation method thereof Download PDF

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Publication number
CN104548044A
CN104548044A CN201510040169.4A CN201510040169A CN104548044A CN 104548044 A CN104548044 A CN 104548044A CN 201510040169 A CN201510040169 A CN 201510040169A CN 104548044 A CN104548044 A CN 104548044A
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herba
parts
radix
externally
preparation
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章莹
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Zhejiang University ZJU
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Zhejiang Medical College
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Abstract

The invention discloses an externally-applied medicine for treating prickly heat. The externally-applied medicine is prepared from the following raw material medicines in parts by weight: 11-13 parts of honeysuckle flower, 8-11 parts of bark of Chinese corktree, 10-15 parts of wrinkled gianthyssop herb, 3-5 parts of common dayflower herb, 5-10 parts of herb of Japanese hop, 10-15 parts of fresh ginger, 8-11 parts of dahurian patrinia herb, 5-10 parts of heartleaf houttuynia herb, 25-30 parts of lightyellow sophora root, 25-30 parts of baikal skullcap root, 25-30 parts of dahurian angelica root, 25-30 parts of peppermint, 25-30 parts of divaricate saposhnikovia root, 3-5 parts of bee honey and 0.1-0.3 part of chitosan. The externally-applied medicine disclosed by the invention takes the effects of clearing heat and removing toxicity as well as cooling blood and diminishing inflammation as base, and ensures that various medicines are combined for use and each medicine is in mutual synergistic interaction to play roles in clearing heat, cooling blood, eliminating dampness, diminishing inflammation and relieving itching, and moistening together, so that burning sensation and pricking caused by prickly heat can be reduced, and the purposes of rapidly treating prickly heat and promoting healing can be achieved; and moreover, the externally-applied medicine does not have irritation or side effects, and is good in use comfort. The invention also discloses a preparation method of the externally-applied medicine for treating prickly heat. The preparation method disclosed by the invention is simple in process step, strong in operability, less in equipment investment and low in cost, and is suitable for industrial production.

Description

a kind of external used medicine for the treatment of miliaria and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, especially relate to a kind of external used medicine for the treatment of miliaria and preparation method thereof.
Background technology
Miliaria is a kind of dermatosis being common in hot season autumn in summer, is common in the places such as women's head-ornaments, neck, thoracic dorsal, oxter, the fossa cubitalis, groin.From the beginning of skin rubefaction, gradually rise and namely occur syringe needle size pimple or papulovesicle, dense arrangement and not merging, slight pruritus, scorching hot twinge, infant and obese people easily suffer from it.
The conventional product of current treatment miliaria removes floral water, outside the Liquor Flos Lonicerae Distillata, and miliaria water of dispelling in addition, dispel miliaria green grass or young crops, prickly-heat powder etc.The main component of the powder such as prickly-heat powder is Pulvis Talci, and Pulvis Talci water absorption is very strong, can block pore; And skin can be made to produce scorching hot sensation of pricking during the use such as floral water, can cause allergic reaction time serious, therefore, use and the treatment of this series products in real life, should be avoided as far as possible.
Such as, the Chinese patent of application publication number CN102462750A, Shen Qing Publication day 2012.05.23 discloses a kind of pharmaceutical composition for the treatment of miliaria, and it is the water preparation be made up of the raw material of following weight proportion, Herba humuli scandentis 10 ~ 15; Medicine chrysanthemum 10 ~ 15; Water 90 ~ 110; Mentholum 0.6 ~ 1; Flos Lonicerae 5 ~ 10; Rhizoma Coptidis 1 ~ 3.During making, after fresh Herba humuli scandentis and medicine chrysanthemum are boiled 15min in water, place a moment, then add Flos Lonicerae and Rhizoma Coptidis, then boil 5min, elimination residue after cooling, add Mentholum and stir evenly.The weak point of this pharmaceutical composition is: (1) this medicine after a procedure, coating place can produce dry and astringent with tighten sense, comfort is poor; (2), when this Chinese medicine composition coats affected part, not easily patient part is spread evenly across; (3) healing in affected part can not be promoted.
Summary of the invention
The present invention be can produce after the pharmaceutical composition coating for the treatment of miliaria in order to solve prior art dry and astringent with tighten sense, comfort is poor, not easily even spread, and the problem healed in affected part can not be promoted, provide a kind of compatibility reasonable, cost is low, non-stimulated and side effect, comfort is good, and coating is evenly, instant effect, the external used medicine for the treatment of miliaria evident in efficacy.
Present invention also offers a kind of preparation method for the treatment of the external used medicine of miliaria, processing step is simple, and workable, equipment investment is few, and cost is low, is applicable to suitability for industrialized production.
To achieve these goals, the present invention is by the following technical solutions:
Treat an external used medicine for miliaria, be made up of the crude drug of following weight portion: 11 ~ 13 portions of Flos Loniceraes, 8 ~ 11 portions of Cortex Phellodendris, 10 ~ 15 portions of Herba Pogostemoniss, 3 ~ 5 parts of Herba Commelinaes, 5 ~ 10 parts of Herba humuli scandentis, 10 ~ 15 portions of Rhizoma Zingiberis Recenss, 8 ~ 11 parts of Herba Patriniae, 5 ~ 10 parts of Herba Houttuyniae, 25 ~ 30 parts of Radix Sophorae Flavescentiss, 25 ~ 30 parts of Radix Scutellariaes, 25 ~ 30 parts of Radixs Angelicae Dahuricae, 25 ~ 30 portions of Herba Menthaes, 25 ~ 30 parts of Radix Saposhnikoviaes, 3 ~ 5 parts of Mel, 0.1 ~ 0.3 part of chitosan.In external used medicine of the present invention: Flos Lonicerae has heat-clearing and toxic substances removing, wind-heat dissipating, the effect of antiinflammatory; Cortex Phellodendri has the power of heat clearing and damp drying; Herba Commelinae sweet in the mouth, light, cold in nature, function heat-clearing and toxic substances removing, removing heat from blood, row water, the poison of outstanding kind removing summer-heat is evil; Herba Pogostemonis is used for delivering expelling summer-heat; Herba humuli scandentis has effect of heat-clearing and toxic substances removing; Rhizoma Zingiberis Recens has the effect of the cold expelling that induces sweat, and Herba Commelinae, Herba humuli scandentis detoxicating can be helped antipyretic; Herba Patriniae has the effects such as heat-clearing and toxic substances removing; Herba Houttuyniae acrid in the mouth, cold, return lung meridian, energy heat-clearing and toxic substances removing, inducing diuresis to remove edema; Radix Sophorae Flavescentis has removing heat from blood, heat clearing and damp drying, the merit of diuresis; Radix Scutellariae has the merit of heat clearing and damp drying, eliminating fire and detoxication; The Radix Angelicae Dahuricae has and dispels the wind, the effects such as dampness; Herba Menthae is used for dispelling wind, heat radiation, refrigerant antipruritic, effectively can reduce the scorching hot twinge caused by miliaria and pruritus; Radix Saposhnikoviae has effect of easypro wind, relieving exterior syndrome; Mel is containing the abundant Natural antioxidant, there is removing toxic substances, antibacterial, antiinflammatory, moisten, the various functions such as sepage absorption, and affinity is good, there is good permeability, be easy to be absorbed by the skin, make skin tender and springiness, reduce cicatrization, barrier protection effect is served to wound surface, in addition, the sensation of dryness that after Mel can significantly reduce medication, patient part produces, improves comfort greatly; Chitosan can improve viscosity of the present invention; it is made more easily to be uniformly coated on affected part; and chitosan can form the isolating membrane that can be absorbed by human body of air permeable humidity retaining after being applied to affected part; affected part wound surface can be protected and form wet environment; there is exudation, anti, stop blooding, protect from infection and promote the effects such as affected part healing; chitosan also has absorbability in addition; the effective ingredient in medicine can be adsorbed; make the effective ingredient of medicine longer in the retention time in affected part; thus the action time of prolong drug greatly, make therapeutic effect more remarkable.The present invention is with heat-clearing and toxic substances removing, removing heat from blood, antiinflammatory is this, share by all medicines, the mutual Synergistic of each medicine, play heat clearing away, removing heat from blood, dampness, anti-inflammatory anti-itch, moist effect altogether, thus the scorching hot twinge caused by minimizing miliaria, reach the object of fast treating miliaria Promotive union, and non-stimulated and side effect, comfort is good.
Treat a preparation method for the external used medicine of miliaria, comprise the following steps:
(1) Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae, Mel and chitosan is taken by above-mentioned weight, stand-by.
(2) decoct with water after Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae mixing, filter, obtain filtrate.
(3) add in filtrate and add chitosan again after Mel stirs and stir.
As preferably, in step (2), the addition of water be Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, 5 ~ 10 times of Radix Saposhnikoviae gross mass.
As preferably, in step (2), Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae are all first pulverized and mixing and water adding decocts after crossing 40 mesh sieves.
Therefore, the present invention has following beneficial effect:
(1) external used medicine of the present invention is with heat-clearing and toxic substances removing, removing heat from blood, antiinflammatory is this, share by all medicines, mutual Synergistic, play heat clearing away, removing heat from blood, dampness, anti-inflammatory anti-itch, moist effect altogether, thus the scorching hot twinge effectively reduced caused by miliaria, reach the object of fast treating miliaria Promotive union, and non-stimulated and side effect, comfort is good;
(2) preparation method processing step of the present invention is simple, and workable, equipment investment is few, and cost is low, is applicable to suitability for industrialized production.
Therapeutic effect of the present invention is illustrated by following clinical trial.
1. case selection
Sufferer is totally 120 examples, man 85 example, female 35 example, the oldest 55 years old, minimum 6 months, the course of disease was the longest 1 month, the shortest 2 days, and syringe needle size pimple or papulovesicle appear in the women's head-ornaments of sufferer, neck, thoracic dorsal, oxter, the place such as the fossa cubitalis or groin, skin rubefaction, with slight pruritus, scorching hot twinge.
2. Therapeutic Method
Clean affected part and surrounding skin with warm water, when xerosis cutis, dip external used medicine of the present invention with disinfecting cotton swab, embrocate gently along affected part, make its Colloidal fluid forming one deck homogeneous lean cover affected part, exceed edge, affected part and be about 5cm, being coated with three every day, 3 days is a course for the treatment of; After coating, attention does not allow patient scratch skin with fingernail, and keeps skin clean health, observes the curative effect after patient medication every day, comprises the degree of degree that illing skin flushing and miliaria disappear, skin injury healing.
3. the standard of curative effect evaluation
Cure: damaged skin healing, miliaria disappears, and erubescence disappears, and patient no longer feels pruritus, occurs after drug withdrawal without new miliaria;
Effective: damaged skin healing, miliaria disappears and takes off, and erubescence subtracts and takes off, and pruritus alleviates, and occurs without new miliaria;
Effective: skin lesion heals to some extent, miliaria disappears to some extent and takes off, and erubescence subtracts to some extent and takes off, and pruritus alleviates to some extent, occurs without new miliaria;
Invalid: above each symptom, without alleviating, still constantly has new miliaria of sending out to occur.
4. therapeutic outcome (after the course for the treatment of)
Cure: 112 examples (93.3%); Effective: 6 examples (5%); Effective: 2 examples (1.7%); Invalid: 0 example; Total effective rate 120 example (100%).
Detailed description of the invention
Below by detailed description of the invention, the present invention will be further described.
Embodiment 1
(1) by 11g Flos Lonicerae, 8g Cortex Phellodendri, 10g Herba Pogostemonis, 3g Herba Commelinae, 5g Herba humuli scandentis, 10g Rhizoma Zingiberis Recens, 8g Herba Patriniae, 5g Herba Houttuyniae, 25g Radix Sophorae Flavescentis, 25g Radix Scutellariae, the 25g Radix Angelicae Dahuricae, 25g Herba Menthae, 25g Radix Saposhnikoviae, 3g Mel, the weight proportion of 0.1 chitosan takes each crude drug, stand-by.
(2) Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae pulverized and mix after crossing 40 mesh sieves, adding 5 quality water doubly and decoct, filter, obtain filtrate.
(3) add in filtrate and add chitosan again after Mel stirs and stir.
Embodiment 2
(1) by 13g Flos Lonicerae, 11g Cortex Phellodendri, 15g Herba Pogostemonis, 5g Herba Commelinae, 10g Herba humuli scandentis, 15g Rhizoma Zingiberis Recens, 11g Herba Patriniae, 10g Herba Houttuyniae, 30g Radix Sophorae Flavescentis, 30g Radix Scutellariae, the 30g Radix Angelicae Dahuricae, 30g Herba Menthae, 30g Radix Saposhnikoviae, 5g Mel, the weight proportion of 0.3g chitosan takes each crude drug, stand-by.
(2) Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae pulverized and mix after crossing 40 mesh sieves, adding 10 quality water doubly and decoct, filter, obtain filtrate.
(3) add in filtrate and add chitosan again after Mel stirs and stir.
Embodiment 3
(1) by 12g Flos Lonicerae, 10g Cortex Phellodendri, 12g Herba Pogostemonis, 4g Herba Commelinae, 8g Herba humuli scandentis, 12g Rhizoma Zingiberis Recens, 10g Herba Patriniae, 8g Herba Houttuyniae, 27g Radix Sophorae Flavescentis, 28g Radix Scutellariae, the 26g Radix Angelicae Dahuricae, 27g Herba Menthae, 28g Radix Saposhnikoviae, 4g Mel, the weight proportion of 0.2g chitosan takes each crude drug, stand-by.
(2) Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae pulverized and mix after crossing 40 mesh sieves, adding 6 quality water doubly and decoct, filter, obtain filtrate.
(3) add in filtrate and add chitosan again after Mel stirs and stir.
External used medicine of the present invention with heat-clearing and toxic substances removing, removing heat from blood, antiinflammatory is this, share by all medicines, mutual Synergistic, plays heat clearing away, removing heat from blood, dampness, anti-inflammatory anti-itch, moist effect altogether, thus effectively reduces the scorching hot twinge caused by miliaria, reach the object of fast treating miliaria Promotive union, and can cicatrization be reduced, and non-stimulated and side effect, comfort is good, easily accepted by extensive patients, have a good application prospect.
Above-described embodiment is one of the present invention preferably scheme, not does any pro forma restriction to the present invention, also has other variant and remodeling under the prerequisite not exceeding the technical scheme described in claim.

Claims (4)

1. treat an external used medicine for miliaria, it is characterized in that, be made up of the crude drug of following weight portion: 11 ~ 13 portions of Flos Loniceraes, 8 ~ 11 portions of Cortex Phellodendris, 10 ~ 15 portions of Herba Pogostemoniss, 3 ~ 5 parts of Herba Commelinaes, 5 ~ 10 parts of Herba humuli scandentis, 10 ~ 15 portions of Rhizoma Zingiberis Recenss, 8 ~ 11 parts of Herba Patriniae, 5 ~ 10 parts of Herba Houttuyniae, 25 ~ 30 parts of Radix Sophorae Flavescentiss, 25 ~ 30 parts of Radix Scutellariaes, 25 ~ 30 parts of Radixs Angelicae Dahuricae, 25 ~ 30 portions of Herba Menthaes, 25 ~ 30 parts of Radix Saposhnikoviaes, 3 ~ 5 parts of Mel, 0.1 ~ 0.3 part of chitosan.
2. a preparation method for the external used medicine for the treatment of miliaria as claimed in claim 1, is characterized in that, comprise the following steps:
(1) Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae, Mel and chitosan is taken by above-mentioned weight, stand-by;
(2) decoct with water after Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae mixing, filter, obtain filtrate;
(3) add in filtrate and add chitosan again after Mel stirs and stir.
3. preparation method according to claim 2, it is characterized in that, in step (2), the addition of water be Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, 5 ~ 10 times of Radix Saposhnikoviae gross mass.
4. preparation method according to claim 2, it is characterized in that, in step (2), Flos Lonicerae, Cortex Phellodendri, Herba Pogostemonis, Herba Commelinae, Herba humuli scandentis, Rhizoma Zingiberis Recens, Herba Patriniae, Herba Houttuyniae, Radix Sophorae Flavescentis, Radix Scutellariae, the Radix Angelicae Dahuricae, Herba Menthae, Radix Saposhnikoviae are all first pulverized and mixing and water adding decocts after crossing 40 mesh sieves.
CN201510040169.4A 2015-01-27 2015-01-27 Externally-applied medicine for treating prickly heat and preparation method thereof Pending CN104548044A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107519317A (en) * 2017-08-29 2017-12-29 宁波保税区攀峒信息科技有限公司 A kind of Chinese herbal and crude drugs preparations for alleviating skin symptom

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
林小田等: "《皮肤病中医辨治及食疗》", 30 June 2002, 羊城晚报出版社 *
魏春晓等: "治疗小儿痱子经验方", 《中国民间疗法》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107519317A (en) * 2017-08-29 2017-12-29 宁波保税区攀峒信息科技有限公司 A kind of Chinese herbal and crude drugs preparations for alleviating skin symptom

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