CN104189062A - Pharmaceutical composition for treating burn and itch in intensive care - Google Patents
Pharmaceutical composition for treating burn and itch in intensive care Download PDFInfo
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- CN104189062A CN104189062A CN201410491300.4A CN201410491300A CN104189062A CN 104189062 A CN104189062 A CN 104189062A CN 201410491300 A CN201410491300 A CN 201410491300A CN 104189062 A CN104189062 A CN 104189062A
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Abstract
The invention relates to a pharmaceutical composition for treating burn and itch in the intensive care. The pharmaceutical composition contains polypodium nipponicum mett, lespedesa virgata and other raw materials. The pharmaceutical composition is interactive, has synergistic effects, has the efficacies of dispelling wind and dampness, clearing away heat and detoxifying, enriching blood and moistening dryness, and promoting blood circulation to remove blood stasis and can be used for effectively treating the burn and the itch.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to the pharmaceutical composition for the treatment of burn pruritus in a kind of Intensive Care Therapy.
Background technology
In wound surface of burn patients agglutination and after healing, the quite a while, the longlyest reach several years, can produce scratchiness, can not die away.The extremely difficult inhibition of fire victim oneself does not go to scratch, thereby increases the weight of damage, extends the course of disease, increases paralysed trace.Very thorny in processing.
Summary of the invention
The object of this invention is to provide the pharmaceutical composition for the treatment of burn pruritus in a kind of Intensive Care Therapy.
In order to realize object of the present invention, the invention provides the pharmaceutical composition for the treatment of burn pruritus in a kind of Intensive Care Therapy, the material that it comprises following weight portion: Radix Loxostigmatis griffithii 10-30 part and Herba lespedezae virgatae 1-20 part.
Preferably, the material that in Intensive Care Therapy of the present invention, the pharmaceutical composition for the treatment of burn pruritus comprises following weight portion: 10 parts of 15 parts of Radix Loxostigmatis griffithii and Herba lespedezae virgataes.
More preferably, in Intensive Care Therapy of the present invention, the pharmaceutical composition for the treatment of burn pruritus also comprises the material of following weight portion: Fructus Corni 10-30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-30 part, Herba Siegesbeckiae 10-30 part, Radix Ranunculi Ternati 10-20 part, Herba Bidentis Bipinnatae 10-20 part, Folium Isatidis 10-20 part, Folium seu Fructus Tarennae 10-30 part, Folium Crataegi 10-30 part, Herba Sedi 10-20 part, Herba Violae 1-30 part, Fructus Aurantii Immaturus 1-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, pilea cadierei 1-10 part, Folium Apocyni Veneti 1-20 part, Herba Pileae Cavaleriei 10-40 part, Radix Astragali 10-30 part, Semen Ziziphi Spinosae 1-20 part, Liparis japonica (Miq.) Maxim. 10-30 part, Radix Pulsatillae 10-30 part, Radix Isatidis 10-30 part, Semen Plantaginis 10-30 part, Pheretima 1-10 part and Radix Glycyrrhizae 10-30 part.
More preferably, in Intensive Care Therapy of the present invention, the pharmaceutical composition for the treatment of burn pruritus also comprises the material of following weight portion: 20 parts of Fructus Corni, 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Herba Siegesbeckiaes, 12 parts of Radix Ranunculi Ternatis, 15 parts of Herba Bidentis Bipinnatae, 15 parts of Folium Isatidiss, 20 parts of Folium seu Fructus Tarennaes, 20 parts of Folium Crataegi, 13 parts of Herba Sedis, 10 parts of Herba Violaes, 10 parts of Fructus Aurantii Immaturuss, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of pilea cadiereis, 10 parts of Folium Apocyni Venetves, 20 parts of Herba Pileae Cavalerieis, 15 parts of the Radixs Astragali, 10 parts of Semen Ziziphi Spinosaes, 20 parts of Liparis japonica (Miq.) Maxim., 12 parts of the Radix Pulsatillaes, 15 parts of Radix Isatidis, 20 parts of Semen Plantaginiss, 15 parts, 8 parts of Pheretimas and Radix Glycyrrhizae.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, capsule, soft capsule or patch.
In compositions of the present invention, pilea cadierei, Herba Pileae Cavaleriei and Liparis japonica (Miq.) Maxim. are monarch drug; Radix Loxostigmatis griffithii, Herba lespedezae virgatae, Fructus Corni, Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Siegesbeckiae, Radix Ranunculi Ternati, Herba Bidentis Bipinnatae, Folium Isatidis, Folium seu Fructus Tarennae are ministerial drug; Folium Crataegi, Herba Sedi, Herba Violae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, Folium Apocyni Veneti, the Radix Astragali, Semen Ziziphi Spinosae, the Radix Pulsatillae, Radix Isatidis, Semen Plantaginis, Pheretima are adjuvant drug; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.
Pharmaceutical composition of the present invention interacts, synergism, and dispelling wind damp eliminating, heat-clearing and toxic substances removing, blood enriching and dryness moistening, blood circulation promoting and blood stasis dispelling, can treat burn pruritus effectively.
Detailed description of the invention
Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for the present invention instead of limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.Except as otherwise noted, the percent otherwise in the present invention is percetage by weight.
Embodiment patch of the present invention
1) take 10 grams of 15 grams of Radix Loxostigmatis griffithii and Herba lespedezae virgataes, pulverized 60 mesh sieves, add 600 milliliters of dehydrated alcohol, reflux, extract, 2 hours, filters, and reclaims ethanol, and filtrate is condensed into the thick paste of 1.30 (60 DEG C), is dried to powder;
2) take 20 grams of Fructus Corni, 20 grams of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 grams of Herba Siegesbeckiaes, 12 grams of Radix Ranunculi Ternatis, 15 grams of Herba Bidentis Bipinnatae, 15 grams of Folium Isatidiss, 20 grams of Folium seu Fructus Tarennaes, 20 grams of Folium Crataegi, 13 grams of Herba Sedis, 10 grams of Herba Violaes, 10 grams of Fructus Aurantii Immaturuss, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 9 grams of pilea cadiereis, 10 grams of Folium Apocyni Venetves, 20 grams of Herba Pileae Cavalerieis, 15 grams of the Radixs Astragali, 10 grams of Semen Ziziphi Spinosaes, 20 grams of Liparis japonica (Miq.) Maxim., 12 grams of the Radix Pulsatillaes, 15 grams of Radix Isatidis, 20 grams of Semen Plantaginiss, 15 grams, 8 grams of Pheretimas and Radix Glycyrrhizae, add 6000 ml waters, reflux 3 hours in the flask that condensing tube is housed, then filter, obtain filtrate and filtering residue,
3) by 1) in the powder of gained add 2) in filtrate in, stirs 1 hour, then evaporate to dryness, adds 200 grams of lanolines and 100 grams, vaseline, stirs, and spreads upon equably on 1 meter long 1 meter of wide non-woven fabrics, is then divided into 100.
Experimental example
Physical data
This organizes male 52 examples in the patient that hospital accepts for medical treatment year January of 80 example in January, 2013-2014, female's 28 examples, age 19-45 year, maximum burn surface area 80%, minimum burn surface area 8%.Traumatogenic reason: scald 40 examples, flame burn 22 examples, electric injury 3 examples, electric furnace 3 examples of burning, chemical burn 5 examples, electric arc burn 7 examples.All patients wound surface is cured, and pruritus occurs in therapeutic process, and patient complains endurable, and be difficult to people night and sleep, the behavior of all scratching, 48 examples are scratched.
Treat with the patch of preparing in embodiment, every day 2 times, a patch is sticked in to pruritus place at every turn.Treatment 3 days continuously.
The standard of curative effect evaluation
Effective: original pruritus transference cure, the action of not scratching, sleep night, do not scratch; Effective: original pruritus symptom alleviates, the action of scratching reduces, and night, sleep improvement, did not scratch; Invalid: original pruritus symptom alleviates, the action of scratching does not reduce, and night, sleep was poor, had difficulty in going to sleep, and scratched.
Result
Through treatment, effective 53 examples in 80 routine patients, effective 25 examples, invalid 2 examples, total effective rate 97.5%.And in therapeutic process, do not find obvious untoward reaction.
Claims (5)
1. a pharmaceutical composition for treatment burn pruritus in Intensive Care Therapy, is characterized in that the material that it comprises following weight portion: Radix Loxostigmatis griffithii 10-30 part and Herba lespedezae virgatae 1-20 part.
2. the pharmaceutical composition for the treatment of burn pruritus in Intensive Care Therapy according to claim 1, is characterized in that the material that it comprises following weight portion: 10 parts of 15 parts of Radix Loxostigmatis griffithii and Herba lespedezae virgataes.
3. the pharmaceutical composition for the treatment of burn pruritus in Intensive Care Therapy according to claim 1 and 2, it is characterized in that, it also comprises the material of following weight portion: Fructus Corni 10-30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-30 part, Herba Siegesbeckiae 10-30 part, Radix Ranunculi Ternati 10-20 part, Herba Bidentis Bipinnatae 10-20 part, Folium Isatidis 10-20 part, Folium seu Fructus Tarennae 10-30 part, Folium Crataegi 10-30 part, Herba Sedi 10-20 part, Herba Violae 1-30 part, Fructus Aurantii Immaturus 1-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, pilea cadierei 1-10 part, Folium Apocyni Veneti 1-20 part, Herba Pileae Cavaleriei 10-40 part, Radix Astragali 10-30 part, Semen Ziziphi Spinosae 1-20 part, Liparis japonica (Miq.) Maxim. 10-30 part, Radix Pulsatillae 10-30 part, Radix Isatidis 10-30 part, Semen Plantaginis 10-30 part, Pheretima 1-10 part and Radix Glycyrrhizae 10-30 part.
4. the pharmaceutical composition for the treatment of burn pruritus in Intensive Care Therapy according to claim 3, it is characterized in that, it also comprises the material of following weight portion: 20 parts of Fructus Corni, 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Herba Siegesbeckiaes, 12 parts of Radix Ranunculi Ternatis, 15 parts of Herba Bidentis Bipinnatae, 15 parts of Folium Isatidiss, 20 parts of Folium seu Fructus Tarennaes, 20 parts of Folium Crataegi, 13 parts of Herba Sedis, 10 parts of Herba Violaes, 10 parts of Fructus Aurantii Immaturuss, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of pilea cadiereis, 10 parts of Folium Apocyni Venetves, 20 parts of Herba Pileae Cavalerieis, 15 parts of the Radixs Astragali, 10 parts of Semen Ziziphi Spinosaes, 20 parts of Liparis japonica (Miq.) Maxim., 12 parts of the Radix Pulsatillaes, 15 parts of Radix Isatidis, 20 parts of Semen Plantaginiss, 15 parts, 8 parts of Pheretimas and Radix Glycyrrhizae.
5. the pharmaceutical composition for the treatment of burn pruritus in Intensive Care Therapy according to claim 1, is characterized in that, described pharmaceutical composition can be tablet, dispersible tablet, capsule, soft capsule or patch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410491300.4A CN104189062A (en) | 2014-09-22 | 2014-09-22 | Pharmaceutical composition for treating burn and itch in intensive care |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410491300.4A CN104189062A (en) | 2014-09-22 | 2014-09-22 | Pharmaceutical composition for treating burn and itch in intensive care |
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| CN104189062A true CN104189062A (en) | 2014-12-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410491300.4A Pending CN104189062A (en) | 2014-09-22 | 2014-09-22 | Pharmaceutical composition for treating burn and itch in intensive care |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125926A (en) * | 2015-09-23 | 2015-12-09 | 李小涛 | Medical powder for treating burns and scalds and preparation method of medical powder |
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2014
- 2014-09-22 CN CN201410491300.4A patent/CN104189062A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125926A (en) * | 2015-09-23 | 2015-12-09 | 李小涛 | Medical powder for treating burns and scalds and preparation method of medical powder |
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Application publication date: 20141210 |