CN104529923B - 二烯四氮唑硝基苯类化合物、其制备方法和用途 - Google Patents
二烯四氮唑硝基苯类化合物、其制备方法和用途 Download PDFInfo
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- CN104529923B CN104529923B CN201510017094.8A CN201510017094A CN104529923B CN 104529923 B CN104529923 B CN 104529923B CN 201510017094 A CN201510017094 A CN 201510017094A CN 104529923 B CN104529923 B CN 104529923B
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- 0 CCOC(C=CC=Cc1c(*)cccc1)=O Chemical compound CCOC(C=CC=Cc1c(*)cccc1)=O 0.000 description 4
- CJVJVQOTHQFXMG-UHFFFAOYSA-O [O-][N+](c1ccc(CC2=NNN[NH2+]2)cc1)=O Chemical compound [O-][N+](c1ccc(CC2=NNN[NH2+]2)cc1)=O CJVJVQOTHQFXMG-UHFFFAOYSA-O 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
化合物 | 血小板凝聚的抑制IC50(μM) |
I-1 | 1.28 |
I-2 | 0.93 |
I-3 | 1.96 |
I-4 | 3.35 |
I-5 | 3.61 |
I-6 | 2.68 |
Claims (4)
Priority Applications (1)
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CN201510017094.8A CN104529923B (zh) | 2015-01-13 | 2015-01-13 | 二烯四氮唑硝基苯类化合物、其制备方法和用途 |
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CN201510017094.8A CN104529923B (zh) | 2015-01-13 | 2015-01-13 | 二烯四氮唑硝基苯类化合物、其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
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CN104529923A CN104529923A (zh) | 2015-04-22 |
CN104529923B true CN104529923B (zh) | 2016-06-01 |
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CN201510017094.8A Active CN104529923B (zh) | 2015-01-13 | 2015-01-13 | 二烯四氮唑硝基苯类化合物、其制备方法和用途 |
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CN (1) | CN104529923B (zh) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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KR20080015868A (ko) * | 2005-06-02 | 2008-02-20 | 바이엘 크롭사이언스 아게 | 페닐알킬 치환된 헤테로아릴 유도체 |
CN101544614B (zh) * | 2008-03-24 | 2011-07-20 | 合肥合源药业有限公司 | 磷酸二酯酶ⅲ抑制剂、其制法及其医药用途 |
UY31923A (es) * | 2008-06-23 | 2010-01-29 | Astrazeneca Ab | Nuevos heterociclos para su uso como inhibidores de trombina |
CN104086500B (zh) * | 2014-07-23 | 2015-08-26 | 张远强 | 一种par-1拮抗剂及其用途 |
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- 2015-01-13 CN CN201510017094.8A patent/CN104529923B/zh active Active
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