CN104496923B - 硝基苯二烯四氮唑类化合物、其制备方法和用途 - Google Patents
硝基苯二烯四氮唑类化合物、其制备方法和用途 Download PDFInfo
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- CN104496923B CN104496923B CN201510016258.5A CN201510016258A CN104496923B CN 104496923 B CN104496923 B CN 104496923B CN 201510016258 A CN201510016258 A CN 201510016258A CN 104496923 B CN104496923 B CN 104496923B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
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Description
化合物 | 血小板凝聚的抑制IC50(μM) |
I-1 | 0.49 |
I-2 | 1.50 |
I-3 | 0.74 |
I-4 | 0.91 |
I-5 | 0.53 |
I-6 | 1.08 |
I-7 | 1.96 |
I-8 | 1.75 |
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CN201510016258.5A CN104496923B (zh) | 2015-01-13 | 2015-01-13 | 硝基苯二烯四氮唑类化合物、其制备方法和用途 |
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CN201510016258.5A CN104496923B (zh) | 2015-01-13 | 2015-01-13 | 硝基苯二烯四氮唑类化合物、其制备方法和用途 |
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CN104496923A CN104496923A (zh) | 2015-04-08 |
CN104496923B true CN104496923B (zh) | 2016-04-06 |
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CN101508712A (zh) * | 2009-03-30 | 2009-08-19 | 天津药物研究院 | 含四氮唑结构的葡萄糖苷、其制备方法和用途 |
CN104072434B (zh) * | 2014-07-23 | 2015-12-02 | 张远强 | 间位取代的四氮唑苯乙酮化合物、其制备方法和用途 |
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Denomination of invention: PAR-1 antagonist containing nitrobenzene diene tetrazolium, preparation method thereof and application thereof Effective date of registration: 20170816 Granted publication date: 20160406 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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