CN104478819B - 二烯四氮唑苯胺类化合物、其制备方法和用途 - Google Patents
二烯四氮唑苯胺类化合物、其制备方法和用途 Download PDFInfo
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- CN104478819B CN104478819B CN201510016295.6A CN201510016295A CN104478819B CN 104478819 B CN104478819 B CN 104478819B CN 201510016295 A CN201510016295 A CN 201510016295A CN 104478819 B CN104478819 B CN 104478819B
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- 0 CC1=CC=CC[C@@]1C=CC=CC(**)=O Chemical compound CC1=CC=CC[C@@]1C=CC=CC(**)=O 0.000 description 1
- VJLIVRSXTJEONM-UHFFFAOYSA-N CN(C)c1ccc(Cc2n[nH]nn2)cc1 Chemical compound CN(C)c1ccc(Cc2n[nH]nn2)cc1 VJLIVRSXTJEONM-UHFFFAOYSA-N 0.000 description 1
- WGQNDNCJPVDJRJ-UHFFFAOYSA-O Cc1c(C=CC=CCN2N=C(Cc(cc3)ccc3N(C)C)[NH2+]N2)cccc1 Chemical compound Cc1c(C=CC=CCN2N=C(Cc(cc3)ccc3N(C)C)[NH2+]N2)cccc1 WGQNDNCJPVDJRJ-UHFFFAOYSA-O 0.000 description 1
- NSZKDBAUTQVOAV-MSLMYCKWSA-N Cc1cccc(/C=C/C=C/CBr)c1C Chemical compound Cc1cccc(/C=C/C=C/CBr)c1C NSZKDBAUTQVOAV-MSLMYCKWSA-N 0.000 description 1
- RCUTUCVYCWSFNV-YALUOGEHSA-N Cc1ccccc1/C=C/C=C/CO Chemical compound Cc1ccccc1/C=C/C=C/CO RCUTUCVYCWSFNV-YALUOGEHSA-N 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
化合物 | 血小板凝聚的抑制IC50(μM) |
I-1 | 0.53 |
I-2 | 0.86 |
I-3 | 2.38 |
I-4 | 1.71 |
I-5 | 2.095 --> |
I-6 | 1.34 |
Claims (4)
Priority Applications (1)
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CN201510016295.6A CN104478819B (zh) | 2015-01-13 | 2015-01-13 | 二烯四氮唑苯胺类化合物、其制备方法和用途 |
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CN201510016295.6A CN104478819B (zh) | 2015-01-13 | 2015-01-13 | 二烯四氮唑苯胺类化合物、其制备方法和用途 |
Publications (2)
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CN104478819A CN104478819A (zh) | 2015-04-01 |
CN104478819B true CN104478819B (zh) | 2016-03-30 |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN101508712A (zh) * | 2009-03-30 | 2009-08-19 | 天津药物研究院 | 含四氮唑结构的葡萄糖苷、其制备方法和用途 |
CN104072434B (zh) * | 2014-07-23 | 2015-12-02 | 张远强 | 间位取代的四氮唑苯乙酮化合物、其制备方法和用途 |
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Denomination of invention: Diene tetrazole aniline compound and preparation method and usage thereof Effective date of registration: 20170816 Granted publication date: 20160330 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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Date of cancellation: 20190604 Granted publication date: 20160330 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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Effective date of registration: 20190826 Address after: 526600 Volkswagen Pioneer Park, South Side of Decheng Huanshi Road, Deqing County, Zhaoqing City, Guangdong Province, No. 1207, 1st Building, Second Floor (Residential Reform Business) Patentee after: Zhaoqing Kezhi Automation Equipment Co., Ltd. Address before: Chancheng district has 528000 Taiwan public in Guangdong province Foshan City No. 32 first floor 1636, shop No. 1637 Patentee before: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. |