CN104529923A - 二烯四氮唑硝基苯类化合物、其制备方法和用途 - Google Patents
二烯四氮唑硝基苯类化合物、其制备方法和用途 Download PDFInfo
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- CN104529923A CN104529923A CN201510017094.8A CN201510017094A CN104529923A CN 104529923 A CN104529923 A CN 104529923A CN 201510017094 A CN201510017094 A CN 201510017094A CN 104529923 A CN104529923 A CN 104529923A
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- 0 [O-][N+](C1=CC=C2C1=*C2CC1=N*N=N1)=O Chemical compound [O-][N+](C1=CC=C2C1=*C2CC1=N*N=N1)=O 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
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- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
化合物 | 血小板凝聚的抑制IC50(μM) |
I-1 | 1.28 |
I-2 | 0.93 |
I-3 | 1.96 |
I-4 | 3.35 |
I-5 | 3.61 |
I-6 | 2.68 |
Claims (4)
Priority Applications (1)
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CN201510017094.8A CN104529923B (zh) | 2015-01-13 | 2015-01-13 | 二烯四氮唑硝基苯类化合物、其制备方法和用途 |
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CN201510017094.8A CN104529923B (zh) | 2015-01-13 | 2015-01-13 | 二烯四氮唑硝基苯类化合物、其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
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CN104529923A true CN104529923A (zh) | 2015-04-22 |
CN104529923B CN104529923B (zh) | 2016-06-01 |
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CN (1) | CN104529923B (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101208088A (zh) * | 2005-06-02 | 2008-06-25 | 拜尔农作物科学股份公司 | 苯基烷基取代的杂芳基衍生物 |
WO2009117888A1 (zh) * | 2008-03-24 | 2009-10-01 | 合肥合源药业有限公司 | 磷酸二酯酶iii抑制剂、其制法及其医疗用途 |
WO2009157860A1 (en) * | 2008-06-23 | 2009-12-30 | Astrazeneca Ab | New heterocyclic carboxamides for use as thrombin inhibitors |
CN104086500A (zh) * | 2014-07-23 | 2014-10-08 | 张远强 | 一种par-1拮抗剂及其用途 |
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2015
- 2015-01-13 CN CN201510017094.8A patent/CN104529923B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101208088A (zh) * | 2005-06-02 | 2008-06-25 | 拜尔农作物科学股份公司 | 苯基烷基取代的杂芳基衍生物 |
WO2009117888A1 (zh) * | 2008-03-24 | 2009-10-01 | 合肥合源药业有限公司 | 磷酸二酯酶iii抑制剂、其制法及其医疗用途 |
WO2009157860A1 (en) * | 2008-06-23 | 2009-12-30 | Astrazeneca Ab | New heterocyclic carboxamides for use as thrombin inhibitors |
CN104086500A (zh) * | 2014-07-23 | 2014-10-08 | 张远强 | 一种par-1拮抗剂及其用途 |
Non-Patent Citations (2)
Title |
---|
HUA-MING MIAO等: "Exquisite Synthesis of a Designed PAR-1 Antagonist", 《HELVETICA CHIMICA ACTA》 * |
荆玲等: "抗血栓药的研究进展", 《医学理论与实践》 * |
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CN104529923B (zh) | 2016-06-01 |
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Denomination of invention: Diene tetrazole nitrobenzene compound and preparation method and application thereof Effective date of registration: 20170816 Granted publication date: 20160601 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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Date of cancellation: 20190604 Granted publication date: 20160601 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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Effective date of registration: 20191014 Address after: No.118, block B, high tech entrepreneurship service center, Tongling Economic Development Zone, Anhui Province Patentee after: Tongwei Technology Co., Ltd. Tongling City Address before: Chancheng district has 528000 Taiwan public in Guangdong province Foshan City No. 32 first floor 1636, shop No. 1637 Patentee before: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. |