CN104524442B - One kind treats acute cerebral infarction Chinese medicine - Google Patents
One kind treats acute cerebral infarction Chinese medicine Download PDFInfo
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- CN104524442B CN104524442B CN201410780404.7A CN201410780404A CN104524442B CN 104524442 B CN104524442 B CN 104524442B CN 201410780404 A CN201410780404 A CN 201410780404A CN 104524442 B CN104524442 B CN 104524442B
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Abstract
The present invention relates to one kind to treat acute cerebral infarction Chinese medicine, and it is made up of root tuber of aromatic turmeric, Pollen Typhae, corydalis tuber, Ramulus euonymi, Snakegourd Fruit, the banksia rose, the coptis, the fruit of Chinese magnoliavine, ilex pubescens, arisaema cum bile, pseudo-ginseng, bark of ash, Radix Codonopsis, keel, plantain seed, the radix paeoniae rubrathe, Ramulus Taxilli, the fruit of Cherokee rose, raspberry, dragon's blood.The present invention is inventor on the basis of secret prescription handed down in the family from generation to generation, with reference to the summary of oneself clinical experience for many years, obtained by testing repeatedly, therefore the medicine has the effect of uniqueness to intractable " cerebral infarction " disease, it makes the effective ingredient of medicine quickly enter blood circulation using multiple medicine scientific compatibility, comprehensive measure, reduce blood cholesterol levels, block thrombosis, coronary artery dilator, increase CBF, improve the tolerance of cerebral ischemic, improve cerebral infarction, impaired cranial nerve is repaired, makes " cerebral infarction " disease rehabilitating quickly.Medicine of the present invention has the effect of uniqueness to hypertension, high fat of blood, encephalatrophy, cerebral thrombus, coronary heart disease, cerebral arteriovenous malformation, apoplexy sequelae.And there is the advantages of quick, short treating period, cure rate are high, expense is small.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, more particularly to a kind for the treatment of acute brain prepared using Chinese herbal medicine as raw material
Infarct Chinese medicine.
Background technology
Acute cerebral infarction is also known as cerebral arterial thrombosis, is common ailment of middle-aged and old, frequently-occurring disease, has high fatal rate, high cause
The characteristics of residual rate, illness rate is high, causes patient frequently to seek medical advice, and the number of days to delay work increases, and financial burden aggravates, work, live by
To having a strong impact on.
China progresses into aging society, and the cranial vascular disease incidence of disease is in increase trend.Its disability rate, case fatality rate are very
Height, huge economic expenditure turn into an important social concern.Cardiovascular and cerebrovascular disease is classified as by the World Health Organization endangers the mankind
First killer of health.According to statistics, about 32% people dies from the disease of cardiovascular and cerebrovascular in annual death, not only right
The health of the mankind causes greatly to threaten, and has also aggravated the burden of society.
Though the treatment of cerebral arterial thrombosis has very big progress in recent years, but still can not solve all cerebral arterial thrombosises
The problem that disables of patient, how to make patient is medical etc. as early as possible to ask after the generation and generation for how avoiding cerebral arterial thrombosis being also present
Topic, and at present in terms of the treatments such as neuroprotection, anti-freezing, traditional Chinese medicine without unified standard.Doctor trained in Western medicine typically uses neutral treatment principle,
Anti-freezing, fibrinolytic and anti-platelet aggregation medicine are mainly disabled immediately, dehydration drop cranium pressure, control blood pressure, treat complication and branch
Hold treatment.It is excessive to amount of bleeding or have stress ulcer person, can the styptic that is acted on without intravascular coagulation of short-period used.Middle treatment
It is key link to treat " promoting blood circulation ", should be attached most importance to dissolving stasis, hemostasis is not gone, then haemophilia.
The content of the invention
The purpose of the present invention is to overcome prior art insufficient, and provides that a kind of curative effect is fast, expense is low, has no toxic side effect effectively
Control the Chinese medicine preparation of acute cerebral infarction.
To realize the purpose of the present invention, now depending on following technical scheme.The pharmaceutical preparation is matched somebody with somebody by following parts by weight
The raw material of ratio is made：10-27 parts of root tuber of aromatic turmeric, 5-12 parts of Pollen Typhae, 10-15 parts of corydalis tuber, 10-16 parts of Ramulus euonymi, Snakegourd Fruit 7-14
Part, 10-15 parts of the banksia rose, 6-9 parts of the coptis, 10-16 parts of the fruit of Chinese magnoliavine, 20-347 parts of ilex pubescens, 10-15 parts of arisaema cum bile, pseudo-ginseng
6-10 parts, 10-27 parts of bark of ash, 10-15 parts of Radix Codonopsis, 10-14 parts of keel, 10-15 parts of plantain seed, 10-18 parts of the radix paeoniae rubrathe, mulberry
Parasitic 9-15 parts, 10-20 parts of the fruit of Cherokee rose, 10-23 parts of raspberry, 8-10 parts of dragon's blood.
Fang Xie：
Root tuber of aromatic turmeric：Acrid flavour, hardship, it is cold in nature.Return liver, the heart,Lung channel, there is regulating qi to disperse stagnation, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice, promoting blood circulation to stop
Bitterly, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire are used.
Pollen Typhae：Blood-cooling hemostatic；Blood circulation and stasis-eliminating medicine.Hemostasis, stagnation resolvation is treating stranguria.ForSpit blood, bleeding from five sense organs or subcutaneous tissue, spitting of blood,Uterine bleeding、
Traumatism and bleeding, Amenorrhea,Dysmenorrhoea, gastral cavity abdomen shouting pain, treating swelling and pain by traumatic injury, the wet pain of blood strangury.
Corydalis tuber：Warm-natured, acrid flavour is bitter, enters the heart, spleen, liver, lung, is promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain quality goods, especially with the work(of analgesic
Imitate and be world-famous for.
Ramulus euonymi：Promoting circulation of blood is stimulated the menstrual flow, blood stasis removing analgesic.For irregular menstruation, postpartum congestion and abdominal pain, traumatic injury swelling and pain.
Snakegourd Fruit：It is sweet, cold in nature.There is the wide chest effect of moistening lung eliminating the phlegm, sharp gas.Cough with ropy sputum is treated, it is uncomfortable in chest to have a pain.Snakegourd preparation
ControlCoronary disease and angina pectorisThere is certain curative effect.
The banksia rose：Promoting the circulation of qi, analgesic, invigorating the spleen, helps digestion.
The coptis：Heat-clearing and damp-drying drug, purging intense heat and detonicating.For damp and hot feeling of fullness, acid regurgitation, rush down dysentery, jaundice, unconsciousness due to high fever, internal heat are vomitted
High Sheng, it is vexed, be insomnia,
The fruit of Chinese magnoliavine：Astringe the lung, nourshing kidney, promote the production of body fluid, receive sweat, puckery essence.
Ilex pubescens：It is clearing heat and detoxicating, blood circulation and channel invigorating.Control Buerger's disease, coronary heart disease is inclined caused by cerebrovas-cularaccident
Paralysis.
Arisaema cum bile：Clearing heat and eliminating phlegm, dispelling wind and relieving convulsion.ForPhlegm-heat cough, cough up phlegm yellow thick, middle wind phlegm fan, demented frightened epilepsy.
Pseudo-ginseng：Its is warm-natured, acrid flavour, has scattered silt hemostasis, the effect of detumescence ding-tong, available for treatment bleeding from five sense organs or subcutaneous tissue, has blood in stool, collapses
The diseases such as leakage, spitting of blood, haematemesis, traumatism and bleeding, chest and abdomen shouting pain.
Bark of ash：Evacuate pathogenic wind is wet,Relaxing muscles and tendons network,Clearind deficient heat.For arthralgia pain due to rheumatism,Muscle arteries and veins contraction, skeletal pain,Afternoon tidal fever, it is small
Youngster's infantile malnutrition due to digestive disturbances or intestinalparasites is generated heat.
Radix Codonopsis：With tonifying middle-Jiao and Qi, the effect of strengthening spleen and tonifying lung.
Keel：Transquilization with heavy material tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines, myogenic sore
Plantain seed：With reducing fever and causing diuresis, the effect of removing pattogenic heat from the blood and toxic material from the body.
The radix paeoniae rubrathe：The row stasis of blood, analgesic, cool blood, detumescence.Cure mainly：Control the stagnant Amenorrhea of the stasis of blood, the accumulation of hernia lump in the abdomen, stomachache, hypochondriac pain, bleeding from five sense organs or subcutaneous tissue, blood
Dysentery, discharging fresh blood stool, hot eyes, carbuncle swells, injury from falling down.
Ramulus Taxilli：Filling liver kidney, strengthening the bones and muscles, wind-damp dispelling.
The fruit of Cherokee rose：It is mild-natured, returns spleen, kidney, large intestine,BladderThrough.Matter heavily fortified point is held back puckery；With astringent sperm contracting urine, puckery intestines of astringing the lung, admittedly collapse only
The effect of band.
Raspberry：With liver-kidney tonifying, astringent sperm contracting urine, improving eyesight and other effects.
Dragon's blood：Scattered stasis pain, hemostasia and promoting granulation.
Chinese medicine preparation preparation method of the present invention is as follows：Above-mentioned each Chinese medicine is weighed by prescription, then crushed 150 with pulverizer
Mesh sieve, flashing is ball after being well mixed, as mung bean is big, Chinese medicine as of the present invention.
The present invention be inventor on the basis of secret prescription handed down in the family from generation to generation, with reference to the summary of oneself clinical experience for many years, by repeatedly
Test and obtain, therefore the medicine has the effect of uniqueness to intractable " cerebral infarction " disease, it is using multiple medicine scientific compatibility, comprehensive measure
The effective ingredient of medicine is quickly entered blood circulation, reduce blood cholesterol levels, block thrombosis, coronary artery dilator, increase
Flow is healed, improves the tolerance of cerebral ischemic, improves cerebral infarction, repair impaired cranial nerve, make " cerebral infarction " disease quickly
Rehabilitate.Medicine of the present invention is to hypertension, high fat of blood, encephalatrophy, cerebral thrombus, coronary heart disease, cerebral arteriovenous malformation, apoplexy sequelae
There is the effect of uniqueness.And there is the advantages of quick, short treating period, cure rate are high, expense is small.
Embodiment
Raw material is weighed in following ratio：
10-27 parts of root tuber of aromatic turmeric, 5-12 parts of Pollen Typhae, 10-15 parts of corydalis tuber, 10-16 parts of Ramulus euonymi, 7-14 parts of Snakegourd Fruit, wood
Fragrant 10-15 parts, 6-9 parts of the coptis, 10-16 parts of the fruit of Chinese magnoliavine, 20-347 parts of ilex pubescens, 10-15 parts of arisaema cum bile, pseudo-ginseng 6-10
Part, 10-27 parts of bark of ash, 10-15 parts of Radix Codonopsis, 10-14 parts of keel, 10-15 parts of plantain seed, 10-18 parts of the radix paeoniae rubrathe, Ramulus Taxilli
9-15 parts, 10-20 parts of the fruit of Cherokee rose, 10-23 parts of raspberry, 8-10 parts of dragon's blood.
The Chinese medicine preparation preparation method of the present invention is as follows：Above-mentioned each Chinese medicine is weighed by prescription, then crushed with pulverizer
150 mesh sieves, flashing is ball after being well mixed, as mung bean is big, Chinese medicine as of the present invention.
The present invention Chinese medicine preparation instructions of taking be：3 times a day, every time 6 grams, before meals with warm water delivery service.15 days are 1
The course for the treatment of, continuously take 2 courses for the treatment of.
Experimental result of the present invention in terms of cerebral infarction is treated
（One）General information
All cases of general information are our hospital's inpatient of in September, 2011~2013 year 11, and 90 patients are randomly divided into
Treatment group and each 45 of control group.Treatment group man 26, female 19, age（51~67）It is year, average（60.2±2.1）Year.Its
Middle infarction of basal ganglia 21, cerebral lobe infarct 8, multiple cerebral 7, lacunar infarction 8, Cerebellar Infarction 1.Companion
Language disorder 19, muscular strength 0~I grade 4, II grade 16, III grade 19, IV grade 6.Complication with diabetes 16, merge high
Pionemia 7, complicated hypertension 22.Control group man 28, female 17, age（49~66）Year, average age（59.4±
2.3）Year.Wherein infarction of basal ganglia 19, cerebral lobe infarct 8, multiple cerebral 9, lacunar infarction 7, cerebellum
Infarct 2.Companion language disorder 17, muscular strength 0~I grade 5, II grade 18, III grade 18, IV grade 4.Complication with diabetes
14, merge hyperlipidemia 8, complicated hypertension 23.Two groups of patients are in age, sex, the course of disease and clinical score etc.
Data is statistically analyzed no significant difference（P ＞ 0.05）, there is comparativity.
All cases meet what the cerebrovascular disease academic conference of the 4th, the whole nation was formulated《All kinds of cerebrovascular disease diagnosis will
Point》, tcm diagnosis meets the issue of State Administration of Traditional Chinese Medicine encephalopathic acute disease cooperative groups《Apoplexy diagnoses and efficacy evaluation mark
It is accurate》It is tentative《Apoplexy syndrome differential diagnosis standard》Tentative Chinese medical discrimination hinders key, syndrome of wind-phlegm invading upward for the phlegm-blood stasis of apoplexy apoplex involving the channels and collaterals.Cerebral infarction
Extremely fall ill and check confirmation through head CT or MRI in 72h.
（Two）Experimental method
1. given according to the state of an illness be dehydrated, drop cranium pressure, nutrition cranial nerve, stabilizing blood sugar blood pressure, correct water and rock-soil coupling and
The western medicine routine treatments such as antithrombotic.
2. it is oral that the present invention is given in above-mentioned Primary Care, 3 times a day, 6 grams every time, before meals with warm water delivery service.15
It is 1 course for the treatment of, continuously takes 2 courses for the treatment of.
Present invention composition：10-27 parts of root tuber of aromatic turmeric, 5-12 parts of Pollen Typhae, 10-15 parts of corydalis tuber, 10-16 parts of Ramulus euonymi, melon
7-14 parts of beach wormwood, 10-15 parts of the banksia rose, 6-9 parts of the coptis, 10-16 parts of the fruit of Chinese magnoliavine, 20-347 parts of ilex pubescens, arisaema cum bile 10-15
Part, 6-10 parts of pseudo-ginseng, 10-27 parts of bark of ash, 10-15 parts of Radix Codonopsis, 10-14 parts of keel, 10-15 parts of plantain seed, the radix paeoniae rubrathe 10-
18 parts, 9-15 parts of Ramulus Taxilli, 10-20 parts of the fruit of Cherokee rose, 10-23 parts of raspberry, 8-10 parts of dragon's blood, pill is made.
Observe two groups of neurological scorings:Formulated according to Chinese Neuscience meeting, Chinese neurosurgery association《Brain soldier
Middle neurological impairment degree standards of grading》, close observation consciousness, speech, four limbs muscular strength and walking ability.
Determine blood urine routine, blood platelet, clotting time and bleeding time, hepatic and renal function, blood glucose, blood fat, electrolyte etc., hemorheology
It is each after checking before the treatment to detect 1 time.
（Three）Criterion of therapeutical effect
1st, evaluation criteria reference《Cerebral Apoplexy Nerve Function defect degree standards of grading》Draft, according to nervous function
Defect scores, and divides level Four to judge curative effect with reference to disability degree.It is almost recovered：Neurological deficits score reduces 91%~100%, disease
Residual degree is 0 grade；Marked improvement：Neurological deficits score reduces 46%~90%, and disability degree is 1~3 grade；It is progressive：Nerve
Functional impairment reduces 18%~45%；It is invalid：Neurological deficits score reduces less than 12% or dead.
2、StatisticsHandle：Using SPSS10.0 statistical softwares, measurement data is used（±S）Represent, compare and examined using t
Test and X2Examine.
3 results
3.1 two groups of clinical efficacy treatment results are shown in Table 1.
1 two groups for the treatment of results of table compare n (%)
Compared with after control group treatment, P<0.05
3.2 two groups of pretherapy and post-treatment neurological functional deficit scales are relatively shown in Table 2
Two groups of comparing differences are without conspicuousness before 3.3 results show treatment（P>0.05）, and two groups pretherapy and post-treatment itself is poor
It is different to have conspicuousness（P<0.05）, illustrating two groups of neurological functional deficit has improvement, and treatment group improves more preferably.
2 two groups of pretherapy and post-treatment neurological functional deficit scales of table compare（Point,±S）
With this group before treatment, * P<0.05；Compared with after control group treatment, Δ P<0.05
Influence treatment group of 3.3 sundry items to lab index have a blood test before and after treatment routine urinalysis, blood platelet, go out blood coagulation
The change without exception such as time, hepatic and renal function, blood glucose.
Claims (2)
1. one kind treats acute cerebral infarction Chinese medicine, it is characterised in that it is made up of the Chinese medicine material of following weight proportion：
10-27 parts of root tuber of aromatic turmeric, 5-12 parts of Pollen Typhae, 10-15 parts of corydalis tuber, 10-16 parts of Ramulus euonymi, 7-14 parts of Snakegourd Fruit, the banksia rose
10-15 parts, 6-9 parts of the coptis, 10-16 parts of the fruit of Chinese magnoliavine, 20-347 parts of ilex pubescens, 10-15 parts of arisaema cum bile, pseudo-ginseng 6-10
Part, 10-27 parts of bark of ash, 10-15 parts of Radix Codonopsis, 10-14 parts of keel, 10-15 parts of plantain seed, 10-18 parts of the radix paeoniae rubrathe, Ramulus Taxilli
9-15 parts, 10-20 parts of the fruit of Cherokee rose, 10-23 parts of raspberry, 8-10 parts of dragon's blood.
A kind of 2. preparation method for treating acute cerebral infarction Chinese medicine according to claim 1, it is characterised in that：Claim by prescription
Above-mentioned each Chinese medicine is taken, then crushed 150 mesh sieves with pulverizer, flashing be ball after being well mixed, as mung bean is big, as.
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