CN105106855A

CN105106855A - Traditional Chinese medicine preparation for treating apoplexy sequela

Info

Publication number: CN105106855A
Application number: CN201510601342.3A
Authority: CN
Inventors: 梁俊君; 吕岩; 苏坤雄
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-09-18
Filing date: 2015-09-18
Publication date: 2015-12-02

Abstract

The invention discloses a traditional Chinese medicine preparation for treating apoplexy sequela. The traditional Chinese medicine preparation is prepared from the following selected raw material medicines by weight: 20-30 g of astragalus membranaceus, 10-20 g of sealwort, 10-20 g of seaweed, 10-20 g of peach kernels, 10-20 g of safflower, 10-20 g of leech, 10-20 g of stiff silkworm, 10-20 g of eupolyphaga, 10-20 g of lumbricus, 8-15 g of radix aucklandiae, 8-12 g of Chinese wolfberry, 8-12 g of milkwort, 8-12 g of rhizoma typhonii, 8-12 g of radix curcumae, 8-12 g of scorpio, 8-12 g of ginseng, 8-12 g of benzoin, 8-12 g of borneol, 8-12 g of wild chrysanthemum and 8-12 g of rhizoma curcumae. The medicines are excellent in compatibility and reasonable in composition, and cooperatively play the efficacies of dispelling wind and activating meridian, tonifying the liver and kidney, regulating Qi and blood, relaxing tendons and activating collaterals, and dispelling wind and phlegm; the traditional Chinese medicine preparation is used for treating apoplexy sequela, has the advantages of being definite in curative effect, free of side effect, high in cure rate, low in possibility of relapse, and the like, and is worthy of clinical popularization and application.

Description

A kind of Chinese medicine preparation for the treatment of apoplexy sequela

Technical field

The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating apoplexy sequela.

Background technology

Along with the development of modern medicine; apoplexy (doctor trained in Western medicine is commonly referred to cerebral thrombosis) acute attack crisis life fewer and feweri; but relative be that the suffer stroke crowd of sequela is increasing; because patient has limbs and aphasis; basic living can not be taken care of oneself; mental pressure is comparatively large, often needs household to accompany, and brings very large burden to household and society.Apoplexy sequela mainly contains hemiplegia (hemiplegia), half side physical handicaps, numb limbs and tense tendons, hemianopsia, aphasia.Or crossed paralysis, contralateral sensory disturbance, ophthalmoplegia externa, nystagmus, dyslalia, aphasis, hypomnesis, facial hemiparalysis, dysphagia, food of choking are choked water, ataxia, dizziness headache etc.

At present, western medical treatment apoplexy sequela generally adopts dilatation and vasodilation treatment, mainly improves the blood circulation of brain, increases cerebral blood flow, promotes that collateral circulation is set up, to scheme to reduce infarction size, uses some thrombolytic-anticoagulants simultaneously, notes preventing cerebral edema.But long-term taking is low effort not only, and easily recur, make protracted inflammation continuous, patient easily produces drug dependence, brings very large side effects to health.And the traditional Chinese medical science is usually particular about and is debated disease treating, treating both the principal and secondary aspects of a disease, therefore we utilize multiple Chinese herbal medicine to mix fried Chinese medicine preparation treatment apoplexy sequela and achieve positive effect in recent years.

Summary of the invention

Instant invention overcomes the at present technical deficiency that exists of wind sequela aspect in the treatment, provide a kind of determined curative effect, have no side effect, the high and Chinese medicine preparation not easily recurred of cure rate.

The technical solution adopted in the present invention is: a kind of Chinese medicine preparation for the treatment of apoplexy sequela, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

Radix Astragali 20-30 gram, Rhizoma Polygonati 10-20 gram, Sargassum 10-20 gram, Semen Persicae 10-20 gram, Flos Carthami 10-20 gram, Hirudo 10-20 gram, Bombyx Batryticatus 10-20 gram, eupolyphaga 10-20 gram, Pheretima 10-20 gram, Radix Aucklandiae 8-15 gram, Fructus Lycii 8-12 gram, Radix Polygalae 8-12 gram, Rhizoma Typhonii 8-12 gram, Radix Curcumae 8-12 gram, Scorpio 8-12 gram, Radix Ginseng 8-12 gram, Benzoinum 8-12 gram, Borneolum Syntheticum 8-12 gram, Flos Chrysanthemi Indici 8-12 gram, Rhizoma Curcumae 8-12 gram.

As a kind of prioritization scheme:

Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

The Radix Astragali 20 grams, Rhizoma Polygonati 10 grams, Sargassum 10 grams, 10 grams, Semen Persicae, 10 grams, Flos Carthami, Hirudo 10 grams, Bombyx Batryticatus 10 grams, eupolyphaga 10 grams, Pheretima 10 grams, the Radix Aucklandiae 8 grams, Fructus Lycii 8 grams, Radix Polygalae 8 grams, Rhizoma Typhonii 8 grams, Radix Curcumae 8 grams, Scorpio 8 grams, Radix Ginseng 8 grams, Benzoinum 8 grams, Borneolum Syntheticum 8 grams, Flos Chrysanthemi Indici 8 grams, Rhizoma Curcumae 8 grams.

As a kind of prioritization scheme:

The Radix Astragali 22 grams, Rhizoma Polygonati 12 grams, Sargassum 12 grams, 12 grams, Semen Persicae, 12 grams, Flos Carthami, Hirudo 12 grams, Bombyx Batryticatus 12 grams, eupolyphaga 12 grams, Pheretima 12 grams, the Radix Aucklandiae 9 grams, Fructus Lycii 8 grams, Radix Polygalae 9 grams, Rhizoma Typhonii 8 grams, Radix Curcumae 9 grams, Scorpio 8 grams, Radix Ginseng 9 grams, Benzoinum 9 grams, Borneolum Syntheticum 8 grams, Flos Chrysanthemi Indici 8 grams, Rhizoma Curcumae 9 grams.

As a kind of prioritization scheme:

The Radix Astragali 24 grams, Rhizoma Polygonati 14 grams, Sargassum 14 grams, 14 grams, Semen Persicae, 14 grams, Flos Carthami, Hirudo 14 grams, Bombyx Batryticatus 14 grams, eupolyphaga 14 grams, Pheretima 14 grams, the Radix Aucklandiae 10 grams, Fructus Lycii 9 grams, Radix Polygalae 9 grams, Rhizoma Typhonii 9 grams, Radix Curcumae 9 grams, Scorpio 9 grams, Radix Ginseng 9 grams, Benzoinum 9 grams, Borneolum Syntheticum 9 grams, Flos Chrysanthemi Indici 9 grams, Rhizoma Curcumae 9 grams.

As a kind of prioritization scheme:

The Radix Astragali 26 grams, Rhizoma Polygonati 16 grams, Sargassum 16 grams, 16 grams, Semen Persicae, 16 grams, Flos Carthami, Hirudo 16 grams, Bombyx Batryticatus 16 grams, eupolyphaga 16 grams, Pheretima 16 grams, the Radix Aucklandiae 10 grams, Fructus Lycii 10 grams, Radix Polygalae 10 grams, Rhizoma Typhonii 9 grams, Radix Curcumae 9 grams, complete 10 grams, Radix Ginseng 9 grams, Benzoinum 10 grams, Borneolum Syntheticum 9 grams, Flos Chrysanthemi Indici 10 grams, Rhizoma Curcumae 9 grams.

As a kind of prioritization scheme:

The Radix Astragali 28 grams, Rhizoma Polygonati 18 grams, Sargassum 18 grams, 18 grams, Semen Persicae, 18 grams, Flos Carthami, Hirudo 18 grams, Bombyx Batryticatus 18 grams, eupolyphaga 18 grams, Pheretima 18 grams, the Radix Aucklandiae 12 grams, Fructus Lycii 10 grams, Radix Polygalae 11 grams, Rhizoma Typhonii 11 grams, Radix Curcumae 11 grams, Scorpio 10 grams, Radix Ginseng 11 grams, Benzoinum 10 grams, Borneolum Syntheticum 10 grams, Flos Chrysanthemi Indici 10 grams, Rhizoma Curcumae 11 grams.

As a kind of prioritization scheme:

The Radix Astragali 30 grams, Rhizoma Polygonati 20 grams, Sargassum 20 grams, 20 grams, Semen Persicae, 20 grams, Flos Carthami, Hirudo 20 grams, Bombyx Batryticatus 20 grams, eupolyphaga 20 grams, Pheretima 20 grams, the Radix Aucklandiae 15 grams, Fructus Lycii 12 grams, Radix Polygalae 12 grams, Rhizoma Typhonii 12 grams, Radix Curcumae 12 grams, Scorpio 12 grams, Radix Ginseng 12 grams, Benzoinum 12 grams, Borneolum Syntheticum 12 grams, Flos Chrysanthemi Indici 12 grams, Rhizoma Curcumae 12 grams.

The instructions of taking of above-mentioned Chinese medicine preparation is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, traditionally the method for fried Chinese medicine gets its medicine juice, every day 1 dose, adds clear water 400ml, soaks 30 minutes, first boils rear taking liquid 150ml at a simmer with high heat; Take medicinal liquid 150ml again.By 2 liquid medicine mixings, point morning, late 2 decoction being taken warmly.Every day 1 dose 30 days is 1 course for the treatment of.

The raw material Chinese medicine of above-mentioned Chinese medicine preparation:

The Radix Astragali and Radix Ginseng all belong to QI invigorating good medicine, but Radix Ginseng biases toward strongly invigorating primordial QI.Radix Astragali tool and mending and oiliness feature, and if Radix Ginseng, the tonic compatibility then better effects if such as Radix Codonopsis; There is effect of consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer.Containing the various trace elements such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper in the Radix Astragali, have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely, Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.

Rhizoma Polygonati is used as medicine with rhizome.There is boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney benefiting functions.Be used for the treatment of weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat such as to be quenched one's thirst the disease.In vitro tests shows, Rhizoma Polygonati has resisting pathogenic microbes effect, Rhizoma Polygonati water extraction fluid (1:320) has inhibitory action to Bacillus typhi, staphylococcus aureus, acid-fast bacilli, and 2% Rhizoma Polygonati has inhibitory action in various degree to common causative fungus in sabouraud culture medium.

Sargassum is bitter in the mouth, salty, cold in nature; Return lung, stomach, kidney channel.There is hard masses softening and resolving, effect of expectorant diuretic.Modern pharmacology proves, the close glycoprotein of Sargassum not only can coagulation erythrocyte, tumor cell, lymph corpuscle, yeast, marine bacteria and unicellular blue-green alge, also can promote mouselet and human lymphoid's ball splitting action, improve body immunity.In addition, the fucose of Sargassum has obvious antitumor and anticoagulant active effect.

Semen Persicae, sweet in the mouth, hardship, property is put down; Return lung, liver, large intestine channel.Have blood circulation promoting and blood stasis dispelling, moisturize effect of laxation, Semen Persicae main attack blood stasis and be liver medicine, holding concurrently and dredge the stasis of blood of the skin natural fibre line of meat, is the special medicine that blood stasis blood closes.Bitter to let out stagnant blood, sweet with tissue regeneration promoting blood.

Flos Carthami, acrid in the mouth, warm in nature; GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain." medicineization justice ": Flos Carthami, kind tonneau passages through which vital energy circulates, is gas medicine in blood, can rushes down and can mend, respectively having wonderful justice.If multiplex three, four money, then too pungent temperature, makes blood wander away.With Lignum Sappan removing blood stasis blood, conjunction Cortex Cinnamomi is stimulated the menstrual flow and closes, and assistant is returned, Chinese herbaceous peony controls all over or breast abdomen pricking caused by the stagnation of QI and blood, and this its row is led and invigorates blood circulation also.If use seven, eight points less, with dispersing liver-energy, to help the sea of blood, void of enriching blood greatly, this its adjust smooth and and blood also; If only with two, three points, enter the heart to join painstaking effort, dismiss heart channel pathogenic fire, make blood be in harmonious proportion, this its nourishing and hemopoietic are also; The justice of component number, meagre.

Hirudo contains 177 kinds of trace element such as polypeptide class, heparin, hirudin, aminoacid and analgesia enzyme, dasen and lysozyme, and have effect of removing blood stasis, the effect such as antithrombotic, anticoagulation obviously.Hirudo, is apt to into blood system, for it was bloodthirsty thing originally, therefore kind removing blood stasis, its abnormal smells from the patient is moved and inspired mutually with blood stasis, does not move and inspire mutually with fresh blood, therefore removing blood stasis with potent drugs blood does not hinder fresh blood, clinical conventional Hirudo treatment coronary heart diseases and angina pectoris, acute myocardial infarction, hyperlipidemia and intracerebral hematoma etc. accordingly.Meanwhile, the merit that Hirudo also has dredging water passages removing mass poly-, clinical its treatment edema disease conventional, as nephrotic syndrome, cirrhotic ascites etc., the basis of warming and recuperating the spleen and kidney of being everlasting adds Hirudo, plays the effect of blood stasis dispelling diuretic.

Bombyx Batryticatus, salty in the mouth, pungent, property is put down, and enters liver, lung two warp, can endogenous wind stopping relieving convulsion, anticancer, the mass dissipating and swelling eliminating of relieving internal heat again, arresting convulsion of reducing phlegm, therefore to infantile convulsion, epilepsy and to hold the hot person of expectorant under the arm particularly suitable.Modern pharmacology proves, Bombyx Batryticatus alcohol water-leach liquor all has hypnosis, anticonvulsant action to mice, rabbit; Its extracting solution in vivo, all have stronger anticoagulation outward; Bombyx Batryticatus powder has good hypoglycemic activity; In vitro tests, has slight bacteriostasis to staphylococcus aureus, bacillus pyocyaneus, and the external breathing suppressing human hepatoma cell of its alcohol extract, can be used for the treatment of rectum tumor type polyp.

Eupolyphaga, cold in nature, there is micro-poison.Having is become silted up and is stopped blooding, reducing swelling and alleviating pain, and dredging collateral reason wound, connecing the effects such as muscle symplectic bone, is treating blood disorders traumatology key medicine.

Pheretima, salty in the mouth, cold in nature; Return liver, spleen, urinary bladder channel.There is clearing away heat and relieving the wind syndrome, effect of dampness diuretic.Modern pharmacology proves, Pheretima extracting solution obviously can extend platelet thrombus and fibrinous thrombus formation time, thrombosis length and dry weight is reduced, and reduces blood viscosity.In addition, Pheretima also there is arrhythmia, regulate central nervous system, the effect such as anticancer.

The Radix Aucklandiae, acrid in the mouth, hardship, warm in nature; Return spleen, stomach, lung meridian.There is warming middle-JIAO to promote flow of QI pain relieving, effect of strengthening the spleen to promote digestion intestinal stasis relieving.The Radix Aucklandiae enters blood system can promoting blood circulation, dredging meridian and relieving pain, therefore for blood stasis abdominal mass abdominal mass mass in the abdomen, difficult labour stillborn fetus, stasis amenorrhea bellyache, traumatic injury etc., power of invigorating blood circulation is strong, makes through beniol, stagnant blood, swells and ache from disappearing.

Fructus Lycii scalable body's immunity, can effectively Tumor suppression growth and cell mutation, there is the effect of the aspects such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, improve the environment of human body.

Radix Polygalae is the Chinese medicine of tranquilizing by nourishing the heart.Bitter in the mouth, pungent, warm in nature, GUIXIN, kidney, lung meridian.There is Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, effect of detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.Radix Polygalae enters the heart, spleen channel, reinforcing the heart blood, and its acrid in the mouth still can proof temper, invigorating the heart and spleen, promoting QI circulation for relieving depression, is the good merchantable brand for the melancholia person that belongs to deficiency of both the heart and spleen.

Rhizoma Typhonii is a kind ofly worth very high medicine, can the meridian dredging, and removing toxic substances analgesia, disease therapy is of many uses, and " traditional herbal medicine ", " Chinese medicine voluminous dictionary " are recorded, and Herba Typhonii gigantei bulb hyoscine, by cold-damp, the expectorant that dispels the wind, spasmolytic.Control middle wind-phlegm to stop up, facial hemiparalysis, tetanus; Control traumatic injury, lymphoid tuberculosis.Modern medicine study shows, Herba Typhonii gigantei except above-mentioned medicinal except, all have special medical effect to various furuncle, poison, skin ulcer, furuncle, among the people all have unique curative effect by make up a prescription treatment liver cirrhosis, diabetes of Herba Typhonii gigantei.

Radix Curcumae is the gas medicine of blood system, both regulates the flow of vital energy, again blood stasis dispelling, dialectically commonly uses this product for qi depression to blood stasis person.There is the disease of qi depression to blood stasis clinically, as myocarditis, coronary heart disease feeling of oppression and pain in the chest or companion's angina pectoris, chronic hepatopathy or companion's portal hypertension, immunological disease lung damage or companion pulmonary hypertension, Chronic Cholecystitis & Cholelithiasis, associated with acute ureterolithiasis hematuria etc., these all need to treat by the method for regulating the flow of QI to dissipate blood stasis, Radix Curcumae is applicable medicine, can be equal to use with Radix Bupleuri, the Radix Paeoniae Alba.Modern pharmacology proves, Radix Curcumae volatile oil injection can strengthen fibrinolytic, and passes through raising cAMP content and obvious anticoagulant, thus can play anticoagulant effect.

Scorpio acrid in the mouth, property is put down, poisonous; Return Liver Channel.Endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula." Shandong Chinese herbal medicine handbook " carries: " endogenous wind stopping dredging collateral, spasmolytic.Control thromboangiitis obliterans, tuberculous lymphadenitis, tuberculosis of bone and joint, mumps.”

Benzoinum, property is put down, acrid in the mouth, hardship, GUIXIN warp, spleen channel.Have out and steal clear god, promoting flow of QI and blood, effect of pain relieving.For apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, trusted subordinate's pain, puerperal blood faints, infantile convulsion.

Borneolum Syntheticum has antibacterial, antiinflammatory action, experiment in vitro shows: the Borneolum Syntheticum of higher concentration has bacteriostasis, synthetic borneol is identical with the bacteriostasis of natural Broneolum Syntheticum, Borneolum Syntheticum in Borneolum Syntheticum, isoborneol all have antibacterial action, and all significantly can suppress rat Ovum Gallus domesticus album pedal swelling, isoborneol also has inhibitory action to Oleum Tiglii auricle edema, point out they to liquid ooze out and the scorching swollen process such as tissue edema has inhibitory action.

Flos Chrysanthemi Indici is containing various active compositions such as alantol, yejuhua lactone, aminoacid, trace element, and its aqueous extract has obvious protective effect to cardiovascular system, can improve cardiac output, increases myocardial oxygen delivery amount, the normal physiological function of protection ischemic myocardium.The aeruginous volatile oil of Flos Chrysanthemi Indici water extract and extraction by steam distillation is killed or inhibit activities various pathogens, virus, and the inhibit activities of water extract to staphylococcus aureus, dysentery bacterium, escherichia coli, Bacillus typhi etc. is better than volatile oil; And have antiinflammatory, antioxidation, analgesic activities.

Rhizoma Curcumae is the blood medicine in gas, and the blood in kind dispelling the stagnated QI, with dispelling the stagnated QI removing food stagnancy.Curcumenol, curdione, Oleum Curcumae injection have direct destruction to cancerous cell, can make its degeneration necrosis. and the feature having effect strong and fast.Rhizoma Curcumae has anticoagulation and anti thrombotic action.Thrombus formation time can be made to extend, contraction in length, weight saving, platelet aggregation weakens.Rhizoma Curcumae aqueous extract energy significantly anticoagulant, and obviously can reduce blood viscosity, and shorten erythrocytic electrophoresis time.Its water extract-alcohol precipitation injection 1.13g/kg intravenous injection is formed rat thrombus in vivo also the inhibitory action shown very much.

Apoplexy sequela refers to that apoplexy is through treatment, after mind is recovered, and the symptoms such as left aphasia hemiplegia, facial hemiparalysis.Motherland's medical science is thought, apoplexy sequela is due to flesh internal organs functional disorder, deficiency of vital QI, and at emotional stress, overstrain internal injury, cause congestion retardance, expectorant Re Neisheng, hyperactivity of heart-fire, extreme hyperactivity of the liver-yang, fire and wind stirring up each other, QI and blood is disorderly inverse, above offends brain and is formed.Therefore treatment is worked as based on promoting flow of QI and blood, dispelling wind and removing obstruction in the collateral, liver and kidney tonifying, blood-activating analgetic.

In Chinese medicine preparation of the present invention, the Radix Astragali, Radix Ginseng, Rhizoma Polygonati, Fructus Lycii, Rhizoma Typhonii can vigorate qi and replenish the blood, warming the meridian for promoting the flow of YANG QI, dispersing cold for relieving pain, increasing intelligence of calming the nerves, play conditioning viscera, strengthening the body resistance, the effect of raising body immunity; Semen Persicae, Flos Carthami, Hirudo, eupolyphaga energy removing blood stasis with potent drugs blood do not hinder fresh blood, specially enter blood system and not to feel frustrated point, therefore the removing blood stasis stasis of blood, loosely gather, qualcomm meridian, dredging water passages, and the power of its removing blood stasis and activating blood flow is especially strong; Sargassum, Bombyx Batryticatus, Pheretima, Scorpio have effect of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, dampness diuretic, toxic dampness and heat in body can be dispelled, removing obstruction in the collateral to relieve pain, be used for the treatment of apoplexy syncope due to accumulation of phlegm and the paralysis caused, sufficient fistula arthralgia pain, spasm of muscles and vessels, lumbago and skelalgia, and it is tall and erect effective in cure to fall macrolesion, walking disorder etc.; Borneolum Syntheticum, Flos Chrysanthemi Indici energy heat-clearing and toxic substances removing, reducing swelling and alleviating pain, have obvious anti-inflammation virus killing effect; The Radix Aucklandiae, the promoting QI circulation for relieving depression of Radix Polygalae energy, invigorating the heart and spleen, warming middle-JIAO to promote flow of QI, tranquilizing by nourishing the heart; Radix Curcumae, Benzoinum, Rhizoma Curcumae both promoting flow of QI and blood, blood-activating analgetic again, has significant anticoagulation and anti thrombotic action, and thrombus formation time can be made to extend, contraction in length, weight saving, platelet aggregation weakens.All medicine compatibilities are superior, reasonable recipe, play effect of liver and kidney tonifying, QI and blood regulating, blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping, nourishing blood to tranquillize the mind altogether, show through clinical observation material, Chinese medicine of the present invention has effect of anticoagulation, anti-stroke and blood circulation promoting and blood stasis dispelling, immunity of organisms and repair function can be improved, can cerebral blood circulation be strengthened again, reduce blood viscosity, promote to remove intracranial hematoma block, anticoagulant and thrombosis, make blood circulation smooth and easy.The more important thing is and directly can protect brain cell, activate the compensation of normal brain cells, inherently recover function of nervous system, the apoplexy sequela such as numb hand and foot, facial hemiparalysis, paralysis is effectively treated.

For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected 60 routine Patients with Apoplexy Sequelas, and all patients meet the diagnostic criteria that the 4th the national cerebrovascular academic conference of nineteen ninety-five Chinese Medical Association is formulated, and confirm through Cranial Computed Tomography scanning.Wherein man 35 example, female 25 example; In age 35-77 year, average 55.2 ± 43 years old, mostly be old people; Course of disease 5-16 days, average 12.3 ± 4.2 days.All patients are divided into treatment group and matched group at random, often organize 30 examples.Two groups of patients equal not statistically significant of comparing difference (P > 0.05) in age, sex, the course of disease, disease type etc., has comparability.

Observation index:

(1) neurological deficits score and daily life behavioral competence (ADL) standards of grading are adopted to come neurological deficit situation and the viability deletion condition of evaluate patient.After treatment, evaluation in every 2 weeks once; (2) routine examination such as electrocardiogram and hemorheology, 1 time weekly; (3) give and anti symptom treatment the pathological changes persons such as original hypertension, diabetes, coronary heart disease are corresponding.

Therapeutic Method:

Treatment group takes Chinese medicine preparation of the present invention, get the Radix Astragali 26 grams, Rhizoma Polygonati 16 grams, Sargassum 16 grams, 16 grams, Semen Persicae, 16 grams, Flos Carthami, Hirudo 16 grams, Bombyx Batryticatus 16 grams, eupolyphaga 16 grams, Pheretima 16 grams, the Radix Aucklandiae 10 grams, Fructus Lycii 10 grams, Radix Polygalae 10 grams, Rhizoma Typhonii 9 grams, Radix Curcumae 9 grams, complete 10 grams, Radix Ginseng 9 grams, Benzoinum 10 grams, Borneolum Syntheticum 9 grams, Flos Chrysanthemi Indici 10 grams, Rhizoma Curcumae 9 grams (with disease plus-minus), after getting its medicine juice by above-mentioned decocting method, point morning, late 2 decoction being taken warmly.Every day 1 dose 30 days is 1 course for the treatment of.

Matched group carries out routine medication by Neurology Department diagnosis and treatment specification, namely gives the treatments such as Aspirin Enteric-coated Tablets, nimodipine, troxerutin.To keep quite as far as possible in two groups of patient treatment procedure environment, lie up more, actively carry out the measures such as some psychotherapys simultaneously.Two groups all in treatment observe the curative effect after 2 months.

Criterion of therapeutical effect:

Cure: symptom disappears substantially, and sign and blood fat blood viscosity Index for examination are clearly better, limb functional recover, and life can take care of oneself;

Effective: symptom major part disappears, and suffering limb muscular strength increases by 2 grades, and blood fat blood viscosity Index for examination improves, and basic living can be taken care of oneself;

Effective: symptom part takes a turn for the better, and suffering limb muscular strength increases by 1 grade, and blood fat blood viscosity Index for examination makes moderate progress;

Invalid: before and after treatment, the Index for examinations such as symptom, suffering limb muscular strength, blood fat blood viscosity are all without improvement.

Efficacy result:

1. clinical efficacy result

After treatment, treatment group cures 18 examples, effective 7 examples, effective 4 examples, invalid 1 example, and cure rate is 36.0%, and effective percentage is 96.7%; Matched group cures 8 examples, effective 4 examples, effective 11 examples, invalid 7 examples, cure rate 26.7%, effective percentage 76.7%.The cure rate for the treatment of group, effective percentage are apparently higher than matched group, and between group, comparing difference significantly (P < 0.05), has statistical significance.Detailed results is in table 1.

Table 1: clinical efficacy result synopsis after two groups of treatments

Group	Number of cases	Cure (%)	Effective (%)	Effectively (%)	Invalid (%)	Total effective rate (%)
							Treatment group	30	18(36.0)	7(23.3)	4(13.3)	1(3.3)	96.7
Matched group	30	8(26.7)	4(13.3)	11(36.7)	7(23.3)	76.7

2. liang group electrocardiogram and blood stream rheology compare:

Matched group all has improvement in various degree before comparing treatment with the electrocardiogram display for the treatment of group with hemodynamic index (hematocrit value, Plasma Viscosity, Fibrinogen) weekly, and through statistical procedures, treatment group improves degree due to matched group.

3. a liang group neurological deficits score improvement is compared (with reference to nineteen ninety-five clinical neurologic deficit of stroke patients degree standards of grading scoring):

Two groups are carried out functional impairment evaluation all before the treatment, and within every 2 weeks, carry out a functional impairment evaluation after the treatment, all be improved (P < 0.05) after two groups of treatments, but treatment group is improved situation and is obviously better than matched group, between group, comparing difference has significance (P < 0.05), and detailed results is in table 2.

Table 2: two groups of neurological deficits score improve comparison sheet ( point)

3. bad should be compared:

Two groups of patients all do not find obvious adverse reaction in the treatment.

Result shows, the present invention, as the Chinese medicine preparation for the treatment of apoplexy sequela, effectively can control the symptom of apoplexy sequela, improve quality of life of patient, prevention of recurrence, evident in efficacy, and convenient oral, without obvious adverse reaction, be worth promotion and application clinically.

Detailed description of the invention

Embodiment 1: a kind of Chinese medicine preparation for the treatment of apoplexy sequela, chooses the Radix Astragali 20 grams, Rhizoma Polygonati 10 grams, Sargassum 10 grams, 10 grams, Semen Persicae, 10 grams, Flos Carthami, Hirudo 10 grams, Bombyx Batryticatus 10 grams, eupolyphaga 10 grams, Pheretima 10 grams, the Radix Aucklandiae 8 grams, Fructus Lycii 8 grams, Radix Polygalae 8 grams, Rhizoma Typhonii 8 grams, Radix Curcumae 8 grams, Scorpio 8 grams, Radix Ginseng 8 grams, Benzoinum 8 grams, Borneolum Syntheticum 8 grams, Flos Chrysanthemi Indici 8 grams, Rhizoma Curcumae 8 grams.

Embodiment 2: a kind of Chinese medicine preparation for the treatment of apoplexy sequela, chooses the Radix Astragali 22 grams, Rhizoma Polygonati 12 grams, Sargassum 12 grams, 12 grams, Semen Persicae, 12 grams, Flos Carthami, Hirudo 12 grams, Bombyx Batryticatus 12 grams, eupolyphaga 12 grams, Pheretima 12 grams, the Radix Aucklandiae 9 grams, Fructus Lycii 8 grams, Radix Polygalae 9 grams, Rhizoma Typhonii 8 grams, Radix Curcumae 9 grams, Scorpio 8 grams, Radix Ginseng 9 grams, Benzoinum 9 grams, Borneolum Syntheticum 8 grams, Flos Chrysanthemi Indici 8 grams, Rhizoma Curcumae 9 grams.

Embodiment 3: a kind of Chinese medicine preparation for the treatment of apoplexy sequela, chooses the Radix Astragali 24 grams, Rhizoma Polygonati 14 grams, Sargassum 14 grams, 14 grams, Semen Persicae, 14 grams, Flos Carthami, Hirudo 14 grams, Bombyx Batryticatus 14 grams, eupolyphaga 14 grams, Pheretima 14 grams, the Radix Aucklandiae 10 grams, Fructus Lycii 9 grams, Radix Polygalae 9 grams, Rhizoma Typhonii 9 grams, Radix Curcumae 9 grams, Scorpio 9 grams, Radix Ginseng 9 grams, Benzoinum 9 grams, Borneolum Syntheticum 9 grams, Flos Chrysanthemi Indici 9 grams, Rhizoma Curcumae 9 grams.

Embodiment 4: a kind of Chinese medicine preparation for the treatment of apoplexy sequela, choose the Radix Astragali 26 grams, Rhizoma Polygonati 16 grams, Sargassum 16 grams, 16 grams, Semen Persicae, 16 grams, Flos Carthami, Hirudo 16 grams, Bombyx Batryticatus 16 grams, eupolyphaga 16 grams, Pheretima 16 grams, the Radix Aucklandiae 10 grams, Fructus Lycii 10 grams, Radix Polygalae 10 grams, Rhizoma Typhonii 9 grams, Radix Curcumae 9 grams, complete 10 grams, Radix Ginseng 9 grams, Benzoinum 10 grams, Borneolum Syntheticum 9 grams, Flos Chrysanthemi Indici 10 grams, Rhizoma Curcumae 9 grams.

Embodiment 5: a kind of Chinese medicine preparation for the treatment of apoplexy sequela, chooses the Radix Astragali 28 grams, Rhizoma Polygonati 18 grams, Sargassum 18 grams, 18 grams, Semen Persicae, 18 grams, Flos Carthami, Hirudo 18 grams, Bombyx Batryticatus 18 grams, eupolyphaga 18 grams, Pheretima 18 grams, the Radix Aucklandiae 12 grams, Fructus Lycii 10 grams, Radix Polygalae 11 grams, Rhizoma Typhonii 11 grams, Radix Curcumae 11 grams, Scorpio 10 grams, Radix Ginseng 11 grams, Benzoinum 10 grams, Borneolum Syntheticum 10 grams, Flos Chrysanthemi Indici 10 grams, Rhizoma Curcumae 11 grams.

Embodiment 6: a kind of Chinese medicine preparation for the treatment of apoplexy sequela, chooses the Radix Astragali 30 grams, Rhizoma Polygonati 20 grams, Sargassum 20 grams, 20 grams, Semen Persicae, 20 grams, Flos Carthami, Hirudo 20 grams, Bombyx Batryticatus 20 grams, eupolyphaga 20 grams, Pheretima 20 grams, the Radix Aucklandiae 15 grams, Fructus Lycii 12 grams, Radix Polygalae 12 grams, Rhizoma Typhonii 12 grams, Radix Curcumae 12 grams, Scorpio 12 grams, Radix Ginseng 12 grams, Benzoinum 12 grams, Borneolum Syntheticum 12 grams, Flos Chrysanthemi Indici 12 grams, Rhizoma Curcumae 12 grams.

Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:

Case 1

Guo, man, 60 years old.Could not treat in time after patient suffered stroke before 3 years, after leave over left side paralysis, occur left side paralysis, dysphonia, dysphagia, once arrive many famous hospitals and treated, but had little effect, the state of an illness continue develop.The state of an illness of patient obviously increased the weight of in recent years, clinical all day, word others do not hear, only can eat paste like food, often choke and cough, cough owing to choking and cause pulmonary infection, will be in hospital for several times every year.After under friend recommendation, start to take this Drug therapy, observe patients symptomatic, get the Radix Astragali 26 grams, Rhizoma Polygonati 16 grams, Sargassum 16 grams, 16 grams, Semen Persicae, 16 grams, Flos Carthami, Hirudo 16 grams, Bombyx Batryticatus 16 grams, eupolyphaga 16 grams, Pheretima 16 grams, the Radix Aucklandiae 10 grams, Fructus Lycii 10 grams, Radix Polygalae 10 grams, Rhizoma Typhonii 9 grams, Radix Curcumae 9 grams, complete 10 grams, Radix Ginseng 9 grams, Benzoinum 10 grams, Borneolum Syntheticum 9 grams, Flos Chrysanthemi Indici 10 grams, Rhizoma Curcumae 9 grams (with disease plus-minus), take after decocting, every day 2 times, after two courses for the treatment of, patient mental and muscle power cumulative, function of deglutition takes a turn for the better, have a meal and recover normal, do not choke and cough, can sit gradually.After 1 course for the treatment of of continual cure, patient can stand, and can walk, life substantially can take care of oneself after drug withdrawal.Recurrence of following up a case by regular visits to that so far there are no.

Case 2

Wear certain, man, 66 years old.Patient because of apoplexy hospitalization, gave indwelling gastric tube, urinary catheter before 2 years at that time, and after a series for the treatment of, patient's mind recovers clear, can a little paste like food of oral feeding gradually, right side limb activity comparatively before improve, then leave hospital.After half a year, patient starts to occur that right upper extremity is not independently shaken, and engenders that extremity and cervical region independently do not tremble, and is not improved through the treatment state of an illness, occurs left side paralysis.Upon somebody's introduction, start to take Drug therapy of the present invention, get the Radix Astragali 22 grams, Rhizoma Polygonati 12 grams, Sargassum 12 grams, 12 grams, Semen Persicae, 12 grams, Flos Carthami, Hirudo 12 grams, Bombyx Batryticatus 12 grams, eupolyphaga 12 grams, Pheretima 12 grams, the Radix Aucklandiae 9 grams, Fructus Lycii 8 grams, Radix Polygalae 9 grams, Rhizoma Typhonii 8 grams, Radix Curcumae 9 grams, Scorpio 8 grams, Radix Ginseng 9 grams, Benzoinum 9 grams, Borneolum Syntheticum 8 grams, Flos Chrysanthemi Indici 8 grams, Rhizoma Curcumae 9 grams (with disease plus-minus), take after decocting, every day 2 times, after 1 course for the treatment of, conditions of patients is comparatively front obviously to be improved, and the mental status is better; Language performance comparatively before slightly clear, head and extremity involuntary movement obviously alleviate; Trunk and back strength increase, and can keep seat without support.Altogether through the treatment of 3 courses for the treatment of, patient's freedom of movement, life can take care of oneself after drug withdrawal.Recurrence of following up a case by regular visits to more afterwards that so far there are no.

Case 3

In certain, man, 58 years old, patient was in hospital because of cerebral hemorrhage before 1 year and goes to a doctor, treating had a medical check-up after 3 months starts to occur that left half body is stiff, and pupil is left large and right small, mute, left ear auditory dysesthesia, Consciousness, whole body muscular tension is high, and left side overweights right side, and defecation can oneself control substantially.Be diagnosed as apoplexy sequela.Under friend recommendation, with Chinese medicine preparation treatment of the present invention, observe patients symptomatic, get the Radix Astragali 24 grams, Rhizoma Polygonati 14 grams, Sargassum 14 grams, 14 grams, Semen Persicae, 14 grams, Flos Carthami, Hirudo 14 grams, Bombyx Batryticatus 14 grams, eupolyphaga 14 grams, Pheretima 14 grams, the Radix Aucklandiae 10 grams, Fructus Lycii 9 grams, Radix Polygalae 9 grams, Rhizoma Typhonii 9 grams, Radix Curcumae 9 grams, Scorpio 9 grams, Radix Ginseng 9 grams, Benzoinum 9 grams, Borneolum Syntheticum 9 grams, Flos Chrysanthemi Indici 9 grams, Rhizoma Curcumae 9 grams (with disease plus-minus), after 1 course for the treatment of, the left leg muscle of patient starts to occur twitching, and twitches number of times also showed increased along with treatment number of times increases; Muscle rigidity symptom starts to improve.After 2 courses for the treatment of of continual cure, entire patient's mental status is obviously improved, and before comparatively treating flexibly, upper arm lifts normally for cervical vertebra, knee joint, lower limb, foot activity, and finger is completely independently stretched out, and the recovery of whole body muscular tension, muscular strength of lower limb progressively recovers.Patient and family members very satisfaction.

Claims

1. treat a Chinese medicine preparation for apoplexy sequela, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

5. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

6. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

7. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion: