CN103110843B - Traditional Chinese medicine composition for treating hemorrhagic stroke - Google Patents
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hemorrhagic stroke. The traditional Chinese medicine composition is prepared from white melon, drug darkling beetle, herba lycopi, corydalis amabilis, scorpio, centipede, tabasheer, bitter calabash, poncirus bark, pubescent holly root, and moschus. The traditional Chinese medicine composition can be used for treating the hemorrhagic stroke clinically.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of hemorrhagic apoplexy.
Background technology
Hemorrhagic apoplexy refers in particular to hypertensive cerebral hemorrhage, does not comprise the cerebral hemorrhage that cerebral aneurysm, arteriovenous malformation of brain, blood vessel amyloidosis cause.To the treatment of hemorrhagic apoplexy, primarily, when being to remove hematoma, remove the compressing of hematoma to cerebral tissue, eliminate cerebral edema, to improve ischemia, the anaerobic condition of perihematoma nervous tissue, this is the key for the treatment of success or failure, at present, and western medical treatment, reduce intracranial pressure, eliminate cerebral edema, use brain cell metabolism agent and maintain water and electrolyte balance, but have many problems aspect hemostasis, elimination edema.Draw through inventor's long-term practice, Chinese medicine is controlled hemorrhagic apoplexy and is had better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment hemorrhagic apoplexy that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Merremia yunnanensis, Martianus dermestoides Chevr., Herba Lycopi, Rhizoma Corydalis Decumbentis, Scorpio, Scolopendra, Concretio silicea Bambusae seu schizostachyi, Pericarpium Lagenariae sicerariae, Cortex Ponciri trifoliatae, Radix Ilicis Pubescentis, Moschus according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention and make Merremia yunnanensis 40-60 part, Martianus dermestoides Chevr. 30-50 part, Herba Lycopi 30-50 part, Rhizoma Corydalis Decumbentis 30-50 part, Scorpio 20-25 part, Scolopendra 20-25 part, Concretio silicea Bambusae seu schizostachyi 20-25 part, Pericarpium Lagenariae sicerariae 20-25 part, Cortex Ponciri trifoliatae 10-15 part, Radix Ilicis Pubescentis 10-15 part, Moschus 5-10 part by following raw material medicaments.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 50 parts of Merremia yunnanensis, 40 parts of Martianus dermestoides Chevr., 40 parts of Herba Lycopi, 40 parts of Rhizoma Corydalis Decumbentiss, 22 parts of Scorpios, 22 parts of Scolopendras, 22 parts of Concretio silicea Bambusae seu schizostachyi, 22 parts of Pericarpium Lagenariae sicerariae, 13 parts of Cortex Ponciri trifoliatae, 13 parts of Radix Ilicis Pubescentiss, 8 parts of Moschuss.
The pharmacological action of Chinese medicine of the present invention is as follows:
Merremia yunnanensis: sweet, pungent, flat.Eleminating phlegm and freeing channels.For aphasia due to apoplexy, the disease such as sputum is jammed, hemiplegia.
Martianus dermestoides Chevr.: sweet, pungent, warm.Return lung, stomach, large intestine channel.Warming middle-JIAO is regulated the flow of vital energy, promoting blood circulation and stopping pain, expelling wind and removing dampness.For hemiplegia, the limbs numbness of withering, epersalgia cough, heart peratodynia, the diseases such as menoxenia.
Herba Lycopi: bitter, pungent, tepor.Return liver, spleen channel.Blood circulation promoting and blood stasis dispelling, promoting the circulation of QI for relieving swelling, removing toxicity for eliminating carbuncles.Cure mainly women's amenorrhea, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen edema, traumatic injury, carbuncle sore tumefacting virus etc.
Rhizoma Corydalis Decumbentis: bitter, pungent, cool.Return liver, kidney channel.Expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, removing obstruction in the collateral to relieve pain, blood pressure lowering.For rheumatic arthritis, apoplectic hemiplegia, sciatica, poliomyelitis sequela, lumbar muscle strain, hypertension etc.
Scorpio: salty, pungent, flat, return Liver Channel.Relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.Twitch for infantile convulsion, epilepsy, apoplexy and hemiplegia, rheumatoid arthritis stubborn.
Scolopendra: pungent, warm.Return Liver Channel.Dispel the wind, arresting convulsion, counteracting toxic substances, eliminating stagnation.For apoplexy, rheumatoid arthritis stubborn, skin infection, scrofula etc.
Concretio silicea Bambusae seu schizostachyi: sweet, cold.GUIXIN, gallbladder, Liver Channel.Removing heat-phlegm, cool heart arresting convulsion.For infantile convulsion, epilepsy, middle wind-phlegm fan, calentura coma, expectorant heat syndrome cough such as breathes heavily at the disease.
Pericarpium Lagenariae sicerariae: sweet, light, flat.Return lung, spleen, kidney channel.Diuretic, detumescence, treating stranguria, eliminating stagnation.For edema, ascites, jaundice, quenches one's thirst, gonorrhea, the diseases such as carbuncle.
Cortex Ponciri trifoliatae: pungent, warm.Return liver, kidney channel.Relieving spasm by subduing liver-wind, eleminating phlegm and freeing channels.For apoplexy orthotonus, joint stuffiness, mouthful eye tiltedly waits disease.
Radix Ilicis Pubescentis: bitter, puckery, cold.Return lung, liver, large intestine channel.Heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral.For anemopyretic cold, cough due to lung-heat, pharyngalgia, apoplectic hemiplegia, burn and scald, the diseases such as central serous chorioretinopathy.
Moschus: pungent, warm.GUIXIN, liver, spleen channel.The refreshment of having one's ideas straightened out, blood circulation promoting and dispersing pathogen accumulation, alleviating pain and detumescence.Kill dusk for calentura, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, blood stasis amenorrhea ， lumps in the chest and abdomen, trusted subordinate's shoot, traumatic injury, arthralgia pain numbness, aphtha etc.
Chinese medicine thinks, hemorrhagic apoplexy pathogenesis core is that QI and blood is disorderly contrary, fire and wind stirring up each other, and phlegm and blood stasis, pathogenic heat internal organs is real.Mechanism of qi is against random transformation of fire and occurrence of wind syndrome, attacks to rush the network breakage of brain arteries and veins brain and hyperamization is overflow outside arteries and veins.Blood circulating out of vessels is blood stasis, and " blood is not all right is water " is changed raw for expectorant is for drinking; The turbid mutual knot of blood stasis and expectorant, accumulates raw pathogenic heat, disturbs altogether gods, and numbness resistance venation is heavy be Hitting Viscera, is gently apoplex involving the channels and collaterals.Merremia yunnanensis eleminating phlegm and freeing channels in the present invention, is monarch drug, and Martianus dermestoides Chevr., Herba Lycopi, Rhizoma Corydalis Decumbentis are invigorated blood circulation, blood stasis dispelling, pain relieving, dispel the wind, and is ministerial drug, Scorpio, Scolopendra are expellingged wind and relieving convulsion, activating collaterals and eliminating stagnation, and Concretio silicea Bambusae seu schizostachyi reduces phlegm, Pericarpium Lagenariae sicerariae detumescence, Cortex Ponciri trifoliatae relieving spasm by subduing liver-wind, Radix Ilicis Pubescentis promoting blood circulation to remove obstruction in the collateral, the Moschus refreshment of having one's ideas straightened out.All medicines share and play altogether endogenous wind-evil caused by sthenic liver-energy), the diuretic that eliminates the phlegm, and effect of dredging collateral refreshment finds that through clinical practice hemorrhagic apoplexy is had to unique curative effect.
Chinese medicine composition of the present invention was in 2006 to 2010 the routine patients of clinical observation hemorrhagic apoplexy 56, and clinical report is as follows:
1, physical data
Clinical manifestation has clinical symptoms, the sign of cerebrovascular, and confirms through Cranial Computed Tomography, is diagnosed as cerebral hemorrhage and subarachnoid hemorrhage 56 examples, cerebral hemorrhage 45 examples, subarachnoid hemorrhage 11 examples, male 29 examples, female's 27 examples, average 62.3 years old of age.
2, diagnostic criteria
" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
Hemiplegia, crooked mouth and tongue, speech is stuttering puckery or in silence, feels to go down or disappear, and headache and dizziness, coughs up phlegm or abundant expectoration, abdominal distention dry stool or constipation, dimly red tongue, yellow and greasy fur, stringy and rolling pulse or hemiplegia side stringy and rolling pulse and large.
3, Therapeutic Method
3.1 prescriptions: Merremia yunnanensis 50g, Martianus dermestoides Chevr. 40g, Herba Lycopi 40g, Rhizoma Corydalis Decumbentis 40g, Scorpio 22g, Scolopendra 22g, Concretio silicea Bambusae seu schizostachyi 22g, Pericarpium Lagenariae sicerariae 22g, Cortex Ponciri trifoliatae 13g, Radix Ilicis Pubescentis 13g, Moschus 8g.
3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 15 days were 1 course for the treatment of at 1 dose of every day.Lie up simultaneously, keep airway unobstructed, oxygen uptake, maintain water, electrolyte and acid-base balance, the dehydration of application doctor trained in Western medicine is fallen cranium and is pressed, and controls blood pressure, the treatments such as necessary control infection.
4, therapeutic outcome:
4.1 formulate with reference to " apoplexy diagnosis and efficacy assessment standard ":
Cure: conscious, language function recovers, 3 grades of Myodynamia recoveries are above or normal, can be engaged in simple work, and CT shows that cerebral hemorrhage absorbs completely.
Effective: language performance and limb function are clearly better, muscular strength improves more than 2 grades, and life is taken care of oneself substantially, and CT shows cerebral hemorrhage basic absorption.
Effective: symptom, sign take a turn for the better, and muscular strength improves more than 1 grade, life energy partial self-help, CT shows that cerebral hemorrhage does not absorb, has obvious cerebral edema completely.
Invalid: sings and symptoms is without being clearly better or increasing the weight of, and CT shows unchanged or increases the weight of.
4.2 results: in 56 routine patients, clinical cure 16 examples (28.6%), effective 15 examples (26.8%), effective 18 examples (32.1%), invalid 7 examples (12.5%), total effective rate is 87.5%.
5, model case
5.1 weeks certain, female, 66 years old, angry after burst right side hemiplegia, drowsiness, aphasia, drinking-water is choked and is coughed, urinary incontinence, dysphoria.Have a medical check-up: Bp20/13kPa, drowsiness, that exhales wakes up, aphasia, flushing conjunctival congestion, rough halitosis, rigidity of the neck, a bicker left side is askew, the right avertence that lolls, right side upper and lower extremities muscular strength " 0 " level, right side babinski sign (+), red tongue with yellowish and greasy fur, stringy and rolling pulse is strong.CT shows: right side thalamic hemorrhage is broken into the ventricles of the brain.Be diagnosed as hemorrhagic apoplexy.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, the clear language profit of god, and right side upper and lower extremities muscular strength " 2 " level, continues to take 2 courses for the treatment of, and CT check is shown: absorption of hemorrhage, recovery from illness.
5.2 Chens, man, 56 years old, prominent sense had the pins and needles, numbness of the skin, a mouthful eye is drunk tiltedly then, aphasia, right side hemiplegia, white and greasy fur, floating-rolling pulse, right side upper and lower extremities muscular strength " 0 " level, CT shows: right side thalamic hemorrhage is broken into the ventricles of the brain.Be diagnosed as hemorrhagic apoplexy.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, symptom is clearly better, the clear language profit of god, and right side upper and lower extremities muscular strength " 2 " level, continues to take 2 courses for the treatment of, right side upper and lower extremities muscular strength " 3 " level, CT check is shown: absorption of hemorrhage, recovery from illness.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, a kind of Chinese medicine composition for the treatment of hemorrhagic apoplexy, is to be made up of Merremia yunnanensis 40g, Martianus dermestoides Chevr. 30g, Herba Lycopi 30g, Rhizoma Corydalis Decumbentis 30g, Scorpio 20g, Scolopendra 20g, Concretio silicea Bambusae seu schizostachyi 20g, Pericarpium Lagenariae sicerariae 20g, Cortex Ponciri trifoliatae 10g, Radix Ilicis Pubescentis 10g, Moschus 5g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of hemorrhagic apoplexy, is to be made up of Merremia yunnanensis 50g, Martianus dermestoides Chevr. 40g, Herba Lycopi 40g, Rhizoma Corydalis Decumbentis 40g, Scorpio 22g, Scolopendra 22g, Concretio silicea Bambusae seu schizostachyi 22g, Pericarpium Lagenariae sicerariae 22g, Cortex Ponciri trifoliatae 13g, Radix Ilicis Pubescentis 13g, Moschus 8g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of hemorrhagic apoplexy, is to be made up of Merremia yunnanensis 60g, Martianus dermestoides Chevr. 50g, Herba Lycopi 50g, Rhizoma Corydalis Decumbentis 50g, Scorpio 25g, Scolopendra 25g, Concretio silicea Bambusae seu schizostachyi 25g, Pericarpium Lagenariae sicerariae 25g, Cortex Ponciri trifoliatae 15g, Radix Ilicis Pubescentis 15g, Moschus 10g.
Claims (2)
1. treat a Chinese medicine composition for hemorrhagic apoplexy, it is characterized in that it is to be made up of following raw material medicaments:
Merremia yunnanensis 40-60 part, Martianus dermestoides Chevr. 30-50 part, Herba Lycopi 30-50 part, Rhizoma Corydalis Decumbentis 30-50 part, Scorpio 20-25 part, Scolopendra 20-25 part, Concretio Silicea Bambusae 20-25 part, Pericarpium Lagenariae sicerariae 20-25 part, Cortex Ponciri trifoliatae 10-15 part, Radix Ilicis Pubescentis 10-15 part, Moschus 5-10 part.
2. Chinese medicine composition according to claim 1, is characterized in that it is to be made up of following raw material medicaments:
50 parts of Merremia yunnanensis, 40 parts of Martianus dermestoides Chevr., 40 parts of Herba Lycopi, 40 parts of Rhizoma Corydalis Decumbentiss, 22 parts of Scorpios, 22 parts of Scolopendras, 22 parts of Concretio Silicea Bambusaes, 22 parts of Pericarpium Lagenariae sicerariae, 13 parts of Cortex Ponciri trifoliatae, 13 parts of Radix Ilicis Pubescentiss, 8 parts, Moschus.
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| CN104189393A (en) * | 2014-09-07 | 2014-12-10 | 王旭东 | Traditional Chinese medicine preparation for treating stroke and preparation method thereof |
| CN108186707A (en) * | 2018-03-20 | 2018-06-22 | 云南省药物研究所 | Application of the white clouds melon extract in pharmacy |
Citations (3)
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|---|---|---|---|---|
| CN1565599A (en) * | 2003-06-30 | 2005-01-19 | 李建中 | Chinese drug injection formulation for dissolving cerebral thrombus |
| CN101317982A (en) * | 2008-07-16 | 2008-12-10 | 洛阳梓生科技开发有限公司 | Method for preparing capsule for cooling liver, removing wind, clearing heat and relieving spasm |
| CN102335357A (en) * | 2011-10-20 | 2012-02-01 | 朱良春 | Phlegm eliminating and convulsion arresting powder and application thereof |
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2013
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|---|---|---|---|---|
| CN1565599A (en) * | 2003-06-30 | 2005-01-19 | 李建中 | Chinese drug injection formulation for dissolving cerebral thrombus |
| CN101317982A (en) * | 2008-07-16 | 2008-12-10 | 洛阳梓生科技开发有限公司 | Method for preparing capsule for cooling liver, removing wind, clearing heat and relieving spasm |
| CN102335357A (en) * | 2011-10-20 | 2012-02-01 | 朱良春 | Phlegm eliminating and convulsion arresting powder and application thereof |
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