CN104524084A - Pruritus ani treating bacteriostatic cleaning agent for external use and preparation method thereof - Google Patents
Pruritus ani treating bacteriostatic cleaning agent for external use and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a pruritus ani treating bacteriostatic cleaning agent for external use. The bacteriostatic cleaning agent comprises, by weight, 3-9 parts of centipedes, 15-30 parts of chufa, 10-30 parts of honeysuckle, 3-9 parts of sedum aizoon, 3-10 parts of radix angelicae pubescentis, 15-30 parts of calamine, 15-30 parts of indigo naturalis, 10-20 parts of cortex pseudolaricis, 10-20 parts of wild carrot fruit, 5-9 parts of japonese pearlwort herbs, 3-6 parts of radix sophorae flavescentis, 3-15 parts of cortex dictamni, 15-40 parts of radix angelicae, 10-30 parts of wild chrysanthemum flowers and 10-30 parts of ageratum conyzoides. The bacteriostatic cleaning agent for external use has the remarkable effect on pruritus ani and capable of well treating the pruritus ani caused by the anal fistula, anal fissure and the like. According to the pruritus ani treating bacteriostatic cleaning agent for external use and a preparation method of the bacteriostatic cleaning agent, selected medicinal materials are common medicinal materials in local places, the price is chip, and the financial burden is lowered for patients.
Description
Technical field
The invention discloses one and treat the antibacterial abluent of pruritus ani external, especially a kind of antibacterial abluent of external for the treatment of pruritus ani and preparation method thereof, the invention belongs to traditional Chinese medicine field.
Background technology
Pruritus ani (peritus ani, PA) is a kind of common local pruritus.Podex has sometimes slightly itches, as serious in pruritus, does not prolongedly more then become pruritus.It is a kind of common limitation dysneuria dermatoses.Generally be only limited to perianal, the spread to perineum had, pudendum or scrotum rear.Mostly occur middle aged, old at 20 ~ 40 years old, the youth of less than 20 years old is less, seldom betides child.Man is more common than female, and custom people that is quiet and that seldom move is mostly occurred this pruritus.Secondary cases pruritus has obvious pathogenesis, easily treats; Spontaneous or agnogenic PA not easily cures, and also often recurs, and accounts for whole patient's 50%.Pruritus ani is more common in middle age.Part is the local symptom of general skin pruritus, be then more common in old people.
Symptom: anus, except having the symptom of generation pain, also has the disease that pruritus occurs, is medically called pruritus ani.Patient ceaselessly can scratch with hands because itching, and has even scratched skin and has not also dealt with problems.Its pathogenic factor is as follows: 1. buttocks is not wiped clean, and excrement slag stimulates and causes inflammation to skin.2. anus alveole inflammation, its juice flows out caused by outside anus.3. the rectal mucosa caused because of the sequela of operation is deviate from, or proctoptosis, and enteral mucus sticks in caused by perianal.4. sit agent or the anaphylaxis caused by antipruritic ointment, as diabetes or estrogen exception.5. miliaria, perianal eczema.6. pinworm.7. special neurosis etc.The most often suffering from the people of pruritus ani, is the people that anus is not wiped clean.Therefore paper using please don't wipe anus, and change and clean with warm water.If but clean with towel or soap because itching, instead can make a mess of skin, and form chronic inflammation.Balneation after defecation, cleans anus with absorbent cotton, then uses soft cloth suck dry moisture, spills prickly-heat powder, keeps dry, after four or five days, and can be only overworked.If still can not be antipruritic, then need to look for rectal surgery diagnosis, use medicine to treat.
Authorization Notice No. CN 103239585B (application number 201310177947.5) patent discloses a kind of external medicine composition for the treatment of pruritus ani, it is characterized in that: it is formulated by the raw material of Chinese medicine of following weight, Folium Hibisci Mutabilis 150 grams, Ramulus et Folium Bauhiniae Faberi 150 grams, Herba Diclipterae Chinensis 130 grams, Rhizoma Belamcandae 130 grams, Radix Ilicis Pubescentis 130 grams, Herba Pteridis Multifidae 130 grams, Flos Genkwa 120 grams, Herba Polygoni Avicularis 130 grams, Herba Linderniae Crustaceae 130 grams, Herba clerodendranthi spicati 130 grams, the Radix Angelicae Dahuricae 130 grams, Scolopendra 120 grams, shepherd's purse acenaphthene 130 grams, Semen Ginkgo 130 grams, Folium fici microcarpae 130 grams, Ramulus et Folium Rhinacanthi nasuti 130 grams, Radix Tinosporae 130 grams, Radix Sanguisorbae 130 grams, Folium Artemisiae Argyi 130 grams, Radix Salviae Miltiorrhizae 130 grams, Pterocarya Stenoptera 150 grams, Herba Duchesneae Indicae 130 grams, Sanguis Draxonis 100 grams, sulfur 100 grams, Borneolum Syntheticum 10 grams.Authorization Notice No. CN 102670868B (application number 201210164921.2) patent discloses a kind of ointment for the treatment of allergic dermatitis pruritus ani pruritus vulvae, it is characterized in that: it is made up of the crude drug within the scope of following weight: Oleum Ricini 500-800 gram, Radix Saposhnikoviae 10-20 gram, Herba Asari 20-30 gram, Herba Abri 20-30 gram, Caulis Piperis Kadsurae 15-25 gram, Radix Stephaniae Tetrandrae 10-20 gram, Cortex Acanthopancis 20-30 gram, Stigma Croci 5-10 gram, Colophonium 45-70 gram, Realgar 1-3 gram, Benzoinum 0.5-1.5 gram, Cera Flava 5-10 gram, Camphora 35-45 gram.
As can be seen here, Chinese medicine occupies very important status in treatment pruritus ani, but preparation method is complicated, and great majority are all water preparations, are inconvenient to carry.
Summary of the invention
Along with the development of Chinese Chinese medicine, in Cure and control pruritus ani, people gradually appreciate treatment by Chinese herbs pruritus ani therapeutic process and have no side effect, patient bears painful little, the advantage that cost is saved relatively, for the present situation of existing western medical treatment pruritus ani, an object of the present invention is to provide a kind of antibacterial abluent of external for the treatment of pruritus ani, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat the antibacterial abluent of external of pruritus ani, take off the primary raw material stating weight proportion and be prepared from: Scolopendra 3-9 part, Corm Eleocharitis 15-30 part, Flos Lonicerae 10-30 part, Herba Senecionis Chrysanthemoidis 3-9 part, Radix Angelicae Pubescentis 3-10 part, Calamina 15-30 part, Indigo Naturalis 15-30 part, Cortex Pseudolaricis 10-20 part, Fructus Carotae 10-20 part, Herba Saginae Japonicae 5-9 part, Radix Sophorae Flavescentis 3-6 part, Cortex Dictamni 3-15 part, Radix Angelicae Dahuricae 15-40 part, Flos Chrysanthemi Indici 10-30 part, Herba Agerati Conyzoidis 10-30 part.
Treat the antibacterial abluent of external of pruritus ani, preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Scolopendra 5-9 part, Corm Eleocharitis 16-25 part, Flos Lonicerae 15-25 part, Herba Senecionis Chrysanthemoidis 4-8 part, Radix Angelicae Pubescentis 4-8 part, Calamina 18-28 part, Indigo Naturalis 18-25 part, Cortex Pseudolaricis 12-18 part, Fructus Carotae 14-18 part, Herba Saginae Japonicae 6-8 part, Radix Sophorae Flavescentis 3.5-5 part, Cortex Dictamni 6-14 part, Radix Angelicae Dahuricae 20-38 part, Flos Chrysanthemi Indici 15-28 part, Herba Agerati Conyzoidis 12-28 part.
Treat the antibacterial abluent of external of pruritus ani, better preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Scolopendra 8 parts, Corm Eleocharitis 20 parts, Flos Lonicerae 20 parts, Herba Senecionis Chrysanthemoidis 6 parts, Radix Angelicae Pubescentis 5 parts, Calamina 20 parts, Indigo Naturalis 20 parts, Cortex Pseudolaricis 15 parts, Fructus Carotae 15 parts, Herba Saginae Japonicae 7 parts, Radix Sophorae Flavescentis 4 parts, Cortex Dictamni 12 parts, the Radix Angelicae Dahuricae 30 parts, Flos Chrysanthemi Indici 25 parts, Herba Agerati Conyzoidis 15 parts.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment pruritus ani.
Treat a preparation method for the antibacterial abluent of external of pruritus ani, be prepared from primarily of following step:
1. be placed in clean container by Sal, add the hot water of 70-90 DEG C, instill Oleum sesami after 20-40 minute, take out after being soaked into completely by Calamina, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80-120 mesh sieve;
2. Corm Eleocharitis, Flos Lonicerae and Herba Senecionis Chrysanthemoidis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Cortex Pseudolaricis, spray evenly with the yellow wine burning heat, stewing 3-6 hour, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6-12 minute, grind to form smalls with large ferrum spoon, cross 100-140 mesh sieve;
3. the Radix Angelicae Dahuricae is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5-15 minute, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Fructus Carotae, Herba Saginae Japonicae, Radix Sophorae Flavescentis, Cortex Dictamni, Flos Chrysanthemi Indici and Herba Agerati Conyzoidis are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 50-70 minute, twice filtrate merges, and leaves standstill 3-5 hour;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30-50 minute, obtain drying object, drying object is dry at 70-90 DEG C, both obtained according to every part of 3g subpackage.
The preparation method of the antibacterial abluent of above-mentioned external, 1. step adds the hot water of 75-85 DEG C, instills Oleum sesami (preferred, to add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes) after 25-35 minute.
The preparation method of the antibacterial abluent of above-mentioned external, 2. step sprays evenly with the yellow wine burning heat, stewing 4-5 hour (preferred, spray evenly with the yellow wine burning heat, stewing 4.5 hours).
The preparation method of the antibacterial abluent of above-mentioned external, 2. the Chinese crude drug cooked is placed in rapidly in pot by step, parch 8-10 minute (preferred, to be placed in rapidly in pot by the Chinese crude drug cooked, parch 9 minutes).
The preparation method of the antibacterial abluent of above-mentioned external, 3. the filament cut is placed on and wipes on oily iron plate by step, dries 8-13 minute (preferred, to be placed on by the filament cut and to wipe on oily iron plate, dry 10 minutes).
The preparation method of the antibacterial abluent of above-mentioned external, step 4. twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 55-65 minute (preferred, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes).
The preparation method of the antibacterial abluent of above-mentioned external, 5. thick paste is dried 35-45 minute by step, obtains drying object, by dry at 75-85 DEG C for drying object (preferred, thick paste to be dried 40 minutes, obtain drying object, by drying object drying at 80 DEG C).
The antibacterial abluent of this external, to pruritus ani Be very effective, all has good therapeutical effect to the pruritus ani caused by anal fistula, anal fissure etc., the local common medical material of multiselect of the present invention, cheap, alleviates the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Scolopendra: Scolopendra is medicinal herbs most in use, warm in nature, acrid in the mouth is poisonous.There is the function of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, apoplexy facial hemiparalysis, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Corm Eleocharitis: another name Horse hoof, black taro, Di Li.Flavor efficacy: sweet, cold.Function heat clearing away, reduce phlegm, removing food stagnancy, change wart.Be applicable to that epidemic febrile disease is quenched one's thirst, jaundice, pyretic stranguria, mass in the abdomen, conjunctival congestion, laryngopharynx swelling and pain, wart etc.Prevention acute infectious disease, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, diuresis relieving constipation is eliminated the phlegm, help digestion de-swelling, conditioning hemorrhoid or dysentery is had blood in stool, woman uterine bleeding, lung-dryness syndrome due to deficiency of YIN, phlegm-heat cough, discomfort in the throat, mass in the abdomen are gathered, conjunctival congestion is hidden from view, auxiliary effect such as to bring down a fever.In addition, Corm Eleocharitis contains a kind of antiviral substance can suppress epidemic encephalitis, influenza virus, can be used for the propagation preventing epidemic encephalitis and influenza.
Flos Lonicerae: its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.
Herba Senecionis Chrysanthemoidis: base is former: be root or the herb of Compositae Radix Gynurae platymiscium chrysanthemum leaf Radix Notoginseng.Composition: root is containing alkaloid: aureine., senlciphylline, sineciphyllinine, seneciphyllinine etc.Aerial parts contains PEARLITOL 25C, succinic acid, 5-methyl uracil, adenine, ammonium chloride, Radix gynurae segeti bases, rutin.The property of medicine: sweet, micro-hardship, temperature.Function cures mainly: removing blood stasis, detumescence, hemostasis, pain relieving.Cure mainly treating swelling and pain by traumatic injury, traumatic hemorrhage, congestion is spitted blood, epistaxis, and spitting of blood, has blood in stool, metrorrhagia, dysmenorrhea, stomachache of being retarded by silt puerperal, rheumatalgia, carbuncle sore cellulitis furuncle, worm venom.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Calamina: base is former: be carbonate calcite race's minerals smithsonite or carbonate mineral marionite.Composition: 1. Calamina is mainly old is zinc carbonate, still containing small amounts calcium 0.27%, magnesium oxide 0.45%, ferrum oxide 0.58%, manganese oxide 0.01%.Wherein zinc is often by a small amount of ferrum (bivalence) is replaced.What have still contains a small amount of cobalt, copper, cadmium, lead etc.2. Calamina main component of swimming is basic zinc carbonate, and leaded, the magazine such as cadmium, magnesium, ferrum, aluminum.The property of medicine: sweet, flat.Return liver, spleen, lung meridian.Function cures mainly: improving eyesight removing nebula, and removing dampness is antipruritic, expelling pus and promoting granulation.Cure mainly conjunctival congestion and swelling pain, marginal blepharitis eye, many tear photophobia, nebula film bulbar conjunctiva polyp, ulcer being unable to heal, skin eczema, pudendum pruritus due to damp pathogen.
Indigo Naturalis: have another name called Concha Meretricis Seu Cyclinae powder, indigo-blue flower, for the leaf of Acanthaceae Acanthaceous indigo platymiscium Acanthaceous indigo, Polygonaceae arsesmart polygonum tinctorium ait., pulse family anil Folium et Caulis Indigoferae Tinctoriae, Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort. or stem and leaf are through processing obtained dried powder or agglomerate.The property of medicine: this product is navy blue powder, body is light, and easily fly upward, micro-have careless stink smell, salty in the mouth, cold in nature.Composition: its main component has indirubin, indigo.Find according to modern pharmacological research, this medical instrument has effect of antitumor, anti-inflammatory and antalgic, antiulcer, antibacterial, clearing away heat and cooling blood, removing toxic substances, and for the malicious macule of temperature, laryngopharynx swelling and pain, spits blood, epistaxis, the symptoms such as spitting of blood.
Cortex Pseudolaricis: have another name called arhat Cortex Pini Massonianae, wattle skin, pseudolaricis,cortex is root bark and the near root bark of Pinaceae Pseudolarix plant golden larch.The property of medicine: root bark is irregular strip, distortion and slightly rolling up, not of uniform size, matter is tough, feeble QI, acrid in the mouth, hardship, warm in nature.Composition: root bark contains pseudolaric acid B, betulic acid, myricetin, amaron alcohol A and B etc.Find according to modern pharmacological research, this medical instrument has effect of antifungal, anticancer, expelling wind and removing dampness, killing parasites for relieving itching, for eczema, and neurodermatitis.
Fructus Carotae: be the fruit of Umbelliferae Daucus plant Daucus carota L..Pharmacology: have significant curative effect to Cardiovarscular, has the effect of shrinking uterus.The property of medicine: pungent, bitter, flat, slightly poisonous.Function cures mainly: have parasite killing, removing food stagnancy, antipruritic effect.
Herba Saginae Japonicae: for being the herb of Caryophyllaceae sagina Herba Saginae Japonicae.Composition: cold volatile oil, the sweet and flavone of soap.Pharmacology: the effect with low anticancer, has antitussive, clears phlegm.The property of medicine: bitter, pungent, cool.Return liver, stomach warp.Function cures mainly: removing pathogenic heat from blood and toxic substance from the body, killing parasites for relieving itching.
Radix Sophorae Flavescentis: Radix Sophorae Flavescentis, Chinese medicine name.For the dry root of leguminous plant Radix Sophorae Flavescentis, spring, Qiu Erji excavate, removing root head and little supporting root, cleaning, drying, or take advantage of fresh slices, dry.It is bitter, cold.There is heat clearing and damp drying, parasite killing, the merit of diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.
Cortex Dictamni: bitter, cold.Return through spleen, stomach, urinary bladder channel.Effect: heat clearing and damp drying, removing toxic substances of dispeling the wind.Cure mainly: damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Gui Jing: return lung, spleen, stomach warp.Effect: induce sweat cold expelling, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis, dispelling wind for relieving itching.Cure mainly: anemofrigid cold, headache, toothache, rheumatic arthralgia, nasal sinusitis, leukorrhagia is demonstrate,proved, sore and toxic.
Flos Chrysanthemi Indici: bitter in the mouth, pungent, cool, heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, dissipating blood stasis, improving eyesight, blood pressure lowering.Prevent and treat epidemic cerebrospinal meningitis, prevention influenza, flu, treatment hypertension, hepatitis, dysentery, carbuncle furuncle treatment skin ulcer have positive effect.Function: detumescence.To staphylococcus aureus, diphtheria corynebacterium, streptococcus, bacillus pyocyaneus, puncture Shigella, influenza virus, all there is inhibitory action.
Herba Agerati Conyzoidis: base is former: be the herb of Compositae Ageratum plant Ageratum conyzoides.Composition: herb is containing flavonoid: Herba Agerati Conyzoidis flavone A, B, C, Nobiletin, senensetin, lindera pyrite B, etc.Alkaloid: Lycopodium clavatum amine, Echinatin.Triterpenoid compound: freidelin.Sterols: stigmasterol etc.Volatile oil: Herba Agerati Conyzoidis chromene, coumarin etc.Aerial parts contains chromene class: 7-methoxyl group-2,2-dimethyl chromogen alkene, 7,8-dimethoxy-2 etc.The property of medicine: micro-hardship, pungent, cool.Function cures mainly: heat-clearing and toxic substances removing, hemostasis, pain relieving.Cure mainly cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, spitting of blood, epistaxis, metrorrhagia, epigastric pain, rheumatic arthralgia, traumatic injury, traumatic hemorrhage, thrush, carbuncle furuncle, eczema pruritus.
The antibacterial abluent of external of the present invention debates the principle of disease treatment based on Chinese medicine.Wash open with hot water when the antibacterial abluent of prepared external uses, put into clean container to use, by the TEMPERATURE PURGE anal area of hot water, the present invention is more comprehensive to treatment pruritus ani, affected area administration is rapider, lasting medicine, alleviates the clinical symptoms such as mucosanguineous feces, pruritus ani, anal fistula, anal fissure; Patients ' life quality can be improved; Relapse rate is low, and curative effect is reliable, and effect is stable, has no side effect, has fabulous therapeutical effect to pruritus ani.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds treats the antibacterial abluent of external of pruritus ani, takes off the primary raw material stating weight proportion and is prepared from (getting 3g for every part): Scolopendra 3 parts, Corm Eleocharitis 15 parts, Flos Lonicerae 10 parts, Herba Senecionis Chrysanthemoidis 3 parts, Radix Angelicae Pubescentis 3 parts, Calamina 15 parts, Indigo Naturalis 15 parts, Cortex Pseudolaricis 10 parts, Fructus Carotae 10 parts, Herba Saginae Japonicae 5 parts, Radix Sophorae Flavescentis 3 parts, Cortex Dictamni 3 parts, the Radix Angelicae Dahuricae 15 parts, Flos Chrysanthemi Indici 10 parts, Herba Agerati Conyzoidis 10 parts.
The antibacterial abluent of external for the treatment of pruritus ani, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 70 DEG C, instill Oleum sesami after 20 minutes, take out after being soaked into completely by Calamina, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80 mesh sieves;
2. Corm Eleocharitis, Flos Lonicerae and Herba Senecionis Chrysanthemoidis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Cortex Pseudolaricis, spray evenly with the yellow wine burning heat, stewing 3 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6 minutes, grind to form smalls with large ferrum spoon, cross 100 mesh sieves;
3. the Radix Angelicae Dahuricae is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Fructus Carotae, Herba Saginae Japonicae, Radix Sophorae Flavescentis, Cortex Dictamni, Flos Chrysanthemi Indici and Herba Agerati Conyzoidis are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 50 minutes, twice filtrate merges, and leaves standstill 3 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30 minutes, obtain drying object, drying object is dry at 70 DEG C, both obtained according to every part of 3g subpackage.
Model case one: Zou XX, female, 55 years old, Shenxian County, Liaocheng of Shandong Province personage.Symptom: in January, 2012 cervical cancer month after operation, radiation treatment 21 days, stool band pus and blood 3 days, has a small amount of mucus, and companion's diarrhoea watery stool, uses Norfloxacin in treatment of male poor effect.Proctoscopy: see that intestinal wall is congested, swelling is russet, and occurs serious pruritus ani, the symptom of purple grass oil, healthy and strong, give immediately to suspend only radiotherapy, suggestion uses the antibacterial abluent of gained external of the present invention.
Use and use the antibacterial abluent of embodiment 1 gained external, cleaning treatment 2 days, occur without hemafecia, pruritus alleviates, and continues to use this medicine 2 days, and clinical symptoms disappears completely.
Embodiment 2 one kinds treats the antibacterial abluent of external of pruritus ani, takes off the primary raw material stating weight proportion and is prepared from (getting 3g for every part); Scolopendra 9 parts, Corm Eleocharitis 30 parts, Flos Lonicerae 30 parts, Herba Senecionis Chrysanthemoidis 9 parts, Radix Angelicae Pubescentis 10 parts, Calamina 30 parts, Indigo Naturalis 30 parts, Cortex Pseudolaricis 20 parts, Fructus Carotae 20 parts, Herba Saginae Japonicae 9 parts, Radix Sophorae Flavescentis 6 parts, Cortex Dictamni 15 parts, the Radix Angelicae Dahuricae 40 parts, Flos Chrysanthemi Indici 30 parts, Herba Agerati Conyzoidis 30 parts.
The antibacterial abluent of external for the treatment of pruritus ani, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 90 DEG C, instill Oleum sesami after 40 minutes, take out after being soaked into completely by Calamina, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 120 mesh sieves;
2. Corm Eleocharitis, Flos Lonicerae and Herba Senecionis Chrysanthemoidis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Cortex Pseudolaricis, spray evenly with the yellow wine burning heat, stewing 6 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 12 minutes, grind to form smalls with large ferrum spoon, cross 140 mesh sieves;
3. the Radix Angelicae Dahuricae is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 15 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Fructus Carotae, Herba Saginae Japonicae, Radix Sophorae Flavescentis, Cortex Dictamni, Flos Chrysanthemi Indici and Herba Agerati Conyzoidis are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 70 minutes, twice filtrate merges, and leaves standstill 5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 50 minutes, obtain drying object, drying object is dry at 90 DEG C, both obtained according to every part of 3g subpackage.
Embodiment 3 one kinds treats the antibacterial abluent of external of pruritus ani, takes off the primary raw material stating weight proportion and is prepared from (getting 3g for every part): Scolopendra 5 parts, Corm Eleocharitis 16 parts, Flos Lonicerae 15 parts, Herba Senecionis Chrysanthemoidis 4 parts, Radix Angelicae Pubescentis 4 parts, Calamina 18 parts, Indigo Naturalis 18 parts, Cortex Pseudolaricis 12 parts, Fructus Carotae 14 parts, Herba Saginae Japonicae 6 parts, Radix Sophorae Flavescentis 3.5 parts, Cortex Dictamni 6 parts, the Radix Angelicae Dahuricae 20 parts, Flos Chrysanthemi Indici 15 parts, Herba Agerati Conyzoidis 12 parts.
The antibacterial abluent of external for the treatment of pruritus ani, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 75 DEG C, instill Oleum sesami after 25 minutes, take out after being soaked into completely by Calamina, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 90 mesh sieves;
2. Corm Eleocharitis, Flos Lonicerae and Herba Senecionis Chrysanthemoidis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Cortex Pseudolaricis, spray evenly with the yellow wine burning heat, stewing 4 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6 minutes, grind to form smalls with large ferrum spoon, cross 110 mesh sieves;
3. the Radix Angelicae Dahuricae is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 8 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Fructus Carotae, Herba Saginae Japonicae, Radix Sophorae Flavescentis, Cortex Dictamni, Flos Chrysanthemi Indici and Herba Agerati Conyzoidis are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 55 minutes, twice filtrate merges, and leaves standstill 3.5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 35 minutes, obtain drying object, drying object is dry at 75 DEG C, both obtained according to every part of 3g subpackage.
Embodiment 4 one kinds treats the antibacterial abluent of external of pruritus ani, takes off the primary raw material stating weight proportion and is prepared from (getting 3g for every part): Scolopendra 9 parts, Corm Eleocharitis 25 parts, Flos Lonicerae 25 parts, Herba Senecionis Chrysanthemoidis 8 parts, Radix Angelicae Pubescentis 8 parts, Calamina 28 parts, Indigo Naturalis 25 parts, Cortex Pseudolaricis 18 parts, Fructus Carotae 18 parts, Herba Saginae Japonicae 8 parts, Radix Sophorae Flavescentis 5 parts, Cortex Dictamni 14 parts, the Radix Angelicae Dahuricae 38 parts, Flos Chrysanthemi Indici 28 parts, Herba Agerati Conyzoidis 28 parts.
The antibacterial abluent of external for the treatment of pruritus ani, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 85 DEG C, instill Oleum sesami after 35 minutes, take out after being soaked into completely by Calamina, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 110 mesh sieves;
2. Corm Eleocharitis, Flos Lonicerae and Herba Senecionis Chrysanthemoidis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Cortex Pseudolaricis, spray evenly with the yellow wine burning heat, stewing 5 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 10 minutes, grind to form smalls with large ferrum spoon, cross 130 mesh sieves;
3. the Radix Angelicae Dahuricae is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 13 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Fructus Carotae, Herba Saginae Japonicae, Radix Sophorae Flavescentis, Cortex Dictamni, Flos Chrysanthemi Indici and Herba Agerati Conyzoidis are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 65 minutes, twice filtrate merges, and leaves standstill 4.5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 45 minutes, obtain drying object, drying object is dry at 85 DEG C, both obtained according to every part of 3g subpackage.
Model case two: king XX, man, 49 years old, Harbin, Heilungkiang personage.Symptom: accept radiotherapy in the treatment after operation for cervical carcinoma, 4th week of radiotherapy, there is the malaise symptoms of hemafecia, malaise, go examination in hospital visible intestinal wall under rectoscope congested, be hard and dry 3 days, and perianal pruritus, frowziness, obviously red and swollen, doctor takes hemorrhage and antibiotic medicine treatment, Relapse rate, hears of external of the present invention antibacterial abluent curative effect fine.
Use and use the antibacterial abluent of embodiment 4 gained external, cleaning treatment 3 days, malaise symptoms alleviates, and continue to use the antibacterial abluent of external of the present invention to treat 5 days, clinical symptoms disappears completely.
Embodiment 5 one kinds treats the antibacterial abluent of external of pruritus ani, takes off the primary raw material stating weight proportion and is prepared from (getting 3g for every part): Scolopendra 8 parts, Corm Eleocharitis 20 parts, Flos Lonicerae 20 parts, Herba Senecionis Chrysanthemoidis 6 parts, Radix Angelicae Pubescentis 5 parts, Calamina 20 parts, Indigo Naturalis 20 parts, Cortex Pseudolaricis 15 parts, Fructus Carotae 15 parts, Herba Saginae Japonicae 7 parts, Radix Sophorae Flavescentis 4 parts, Cortex Dictamni 12 parts, the Radix Angelicae Dahuricae 30 parts, Flos Chrysanthemi Indici 25 parts, Herba Agerati Conyzoidis 15 parts.
The antibacterial abluent of external for the treatment of pruritus ani, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes, take out after being soaked into completely by Calamina, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 100 mesh sieves;
2. Corm Eleocharitis, Flos Lonicerae and Herba Senecionis Chrysanthemoidis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Cortex Pseudolaricis, spray evenly with the yellow wine burning heat, stewing 4.5 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 9 minutes, grind to form smalls with large ferrum spoon, cross 120 mesh sieves;
3. the Radix Angelicae Dahuricae is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 10 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Fructus Carotae, Herba Saginae Japonicae, Radix Sophorae Flavescentis, Cortex Dictamni, Flos Chrysanthemi Indici and Herba Agerati Conyzoidis are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes, twice filtrate merges, and leaves standstill 4 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 40 minutes, obtain drying object, drying object is dry at 80 DEG C, both obtained according to every part of 3g subpackage.
Experimental example: 1, selection of clinical: in order to verify the effect of Chinese medicine composition of the present invention, we have extracted 400 patients and have carried out the experiment of medicine, are equally divided into two groups, experimental group and matched group.
2, inclusion criteria: through being diagnosed as pruritus ani patient, has pruritus ani clinical symptoms one or more.
3, Therapeutic Method: adopt the antibacterial abluent of external of the present invention, wash open with hot water, clean, 2 times on the one.
4, curative effect situation criterion: 1, cure.After using medicine, malaise symptoms disappears completely; 2, effective.After using medicine, malaise symptoms alleviates or partial disappearance; 3, invalid.After using medicine, malaise symptoms is unchanged.We conducted the experiment (embodiment 5) of medicine, and accurately statistics and mathematical analysis have been carried out to data.
Specific experiment result is as following table:
Table 1:
Table 2:
Prove through clinical trial, use the antibacterial abluent of external of the present invention compared with the means of western medical treatment pruritus ani, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, have no side effect between the operating period, while treatment pruritus ani, the pruritus ani that a variety of causes causes can be treated.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 98%, has good therapeutical effect to pruritus ani.
Claims (10)
1. treat the antibacterial abluent of external of pruritus ani, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 3-9 part, Corm Eleocharitis 15-30 part, Flos Lonicerae 10-30 part, Herba Senecionis Chrysanthemoidis 3-9 part, Radix Angelicae Pubescentis 3-10 part, Calamina 15-30 part, Indigo Naturalis 15-30 part, Cortex Pseudolaricis 10-20 part, Fructus Carotae 10-20 part, Herba Saginae Japonicae 5-9 part, Radix Sophorae Flavescentis 3-6 part, Cortex Dictamni 3-15 part, Radix Angelicae Dahuricae 15-40 part, Flos Chrysanthemi Indici 10-30 part, Herba Agerati Conyzoidis 10-30 part.
2. the antibacterial abluent of external for the treatment of pruritus ani according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 5-9 part, Corm Eleocharitis 16-25 part, Flos Lonicerae 15-25 part, Herba Senecionis Chrysanthemoidis 4-8 part, Radix Angelicae Pubescentis 4-8 part, Calamina 18-28 part, Indigo Naturalis 18-25 part, Cortex Pseudolaricis 12-18 part, Fructus Carotae 14-18 part, Herba Saginae Japonicae 6-8 part, Radix Sophorae Flavescentis 3.5-5 part, Cortex Dictamni 6-14 part, Radix Angelicae Dahuricae 20-38 part, Flos Chrysanthemi Indici 15-28 part, Herba Agerati Conyzoidis 12-28 part.
3. the antibacterial abluent of external for the treatment of pruritus ani according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 8 parts, Corm Eleocharitis 20 parts, Flos Lonicerae 20 parts, Herba Senecionis Chrysanthemoidis 6 parts, Radix Angelicae Pubescentis 5 parts, Calamina 20 parts, Indigo Naturalis 20 parts, Cortex Pseudolaricis 15 parts, Fructus Carotae 15 parts, Herba Saginae Japonicae 7 parts, Radix Sophorae Flavescentis 4 parts, Cortex Dictamni 12 parts, the Radix Angelicae Dahuricae 30 parts, Flos Chrysanthemi Indici 25 parts, Herba Agerati Conyzoidis 15 parts.
4. the preparation method of the antibacterial abluent of external of the treatment pruritus ani according to any one of claim 1-3, is characterized in that: step is as follows:
1. be placed in clean container by Sal, add the hot water of 70-90 DEG C, instill Oleum sesami after 20-40 minute, take out after being soaked into completely by Calamina, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80-120 mesh sieve;
2. Corm Eleocharitis, Flos Lonicerae and Herba Senecionis Chrysanthemoidis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Cortex Pseudolaricis, spray evenly with the yellow wine burning heat, stewing 3-6 hour, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6-12 minute, grind to form smalls with large ferrum spoon, cross 100-140 mesh sieve;
3. the Radix Angelicae Dahuricae is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5-15 minute, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Fructus Carotae, Herba Saginae Japonicae, Radix Sophorae Flavescentis, Cortex Dictamni, Flos Chrysanthemi Indici and Herba Agerati Conyzoidis are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 50-70 minute, twice filtrate merges, and leaves standstill 3-5 hour;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30-50 minute, obtain drying object, drying object is dry at 70-90 DEG C, both obtained according to every part of 3g subpackage.
5. the preparation method of the antibacterial abluent of external according to claim 4, is characterized in that: 1. step adds the hot water of 75-85 DEG C, instills Oleum sesami (preferred, to add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes) after 25-35 minute.
6. the preparation method of the antibacterial abluent of external according to claim 4, is characterized in that: 2. step sprays evenly with the yellow wine burning heat, stewing 4-5 hour (preferred, spray evenly with the yellow wine burning heat, stewing 4.5 hours).
7. the preparation method of the antibacterial abluent of external according to claim 4, is characterized in that: 2. the Chinese crude drug cooked is placed in rapidly in pot by step, parch 8-10 minute (preferred, to be placed in rapidly in pot by the Chinese crude drug cooked, parch 9 minutes).
8. the preparation method of the antibacterial abluent of external according to claim 4, it is characterized in that: 3. the filament cut is placed on and wipes on oily iron plate by step, dry 8-13 minute (preferred, the filament cut to be placed on and to wipe on oily iron plate, dry 10 minutes).
9. the preparation method of the antibacterial abluent of external according to claim 4, it is characterized in that: step 4. twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 55-65 minute (preferred, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes).
10. the preparation method of the antibacterial abluent of external according to claim 4, is characterized in that: 5. thick paste is dried 35-45 minute by step, obtains drying object, drying object is dry (preferred at 75-85 DEG C, thick paste is dried 40 minutes, obtain drying object, drying object is dry at 80 DEG C).
Priority Applications (1)
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| JP2005170919A (en) * | 2003-12-08 | 2005-06-30 | Hiromi Imanaka | Skin-treating material for pet |
| CN101926919A (en) * | 2009-06-25 | 2010-12-29 | 梁婧卉 | Pure traditional Chinese medicinal lotion for treating skin disease |
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|---|---|---|---|---|
| JP2005170919A (en) * | 2003-12-08 | 2005-06-30 | Hiromi Imanaka | Skin-treating material for pet |
| CN101926919A (en) * | 2009-06-25 | 2010-12-29 | 梁婧卉 | Pure traditional Chinese medicinal lotion for treating skin disease |
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| 俞凯华等: "自制双痒剂治疗肛门瘙痒症120例", 《浙江中西医结合杂志》 * |
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