CN104524048A

CN104524048A - Medicine for treating hydronephrosis

Info

Publication number: CN104524048A
Application number: CN201510065855.7A
Authority: CN
Inventors: 高伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-02-07
Filing date: 2015-02-07
Publication date: 2015-04-22

Abstract

The invention relates to a medicine for treating hydronephrosis. The medicine is prepared from the following medicinal raw materials in parts by weight: 10 parts of herba epimedii, 8 parts of poria cocos, 6 parts of rhizoma alismatis and 5 parts of codonopsis pilosula. In the formula, herba epimedii is spicy, sweet and warm, belongs to liver and kidney meridians and has the effects of tonifying kidney yang, strengthening the bones and muscles and expelling wind-damp; poria cocos belongs to heart, lung, spleen and kidney medians and has the effects of clearing damp and promoting diuresis and tonifying spleen and calming down; rhizoma alismatis belongs to kidney and bladder meridians and has the effects of inducing dieresis and clearing away damp and hot; and codonopsis pilosula belongs to spleen and lung medians and has the effects of strengthening the middle warmer and benefiting vital energy. The medicines are combined in use to jointly play roles of warming yang and fluidizing qi and inducing dieresis and dewetting. Prompted by clinical experiments, the medicine provided by the invention can be safely and effectively applied to treating hydronephrosis.

Description

One is used for the treatment of hydronephrotic medicine

Technical field

The present invention relates to a kind of medicine, be specifically related to one and be used for the treatment of hydronephrotic Chinese medicine.

Background technology

Hydronephrosis is because blocking of urinary system causes renal pelvis and caliectasis, wherein retention urine, is referred to as hydronephrosis.Because urine is gathered in kidney, pressure raises, and renal pelvis and renal calices is expanded and the atrophy of excess of the kidney matter.Urine as retention infects, be then called infectious hydronephrosis; When nephridial tissue, because of infection, necrosis loses function, and renal pelvis is full of pus, is called pyonephrosis or pyonephrosis.The hydronephrotic topmost cause of disease is caused to be that renal pelvic and ureteral tumor blocks.

The reasons such as hydronephrosis is narrow by calculus, tumor, inflammation, tissue adhesion, retroperitoneal fibrosis, EUC cause renal pelvis or ureteral obstruction, thus cause kidney internal water accumulation, infect, cause impaired renal function in the easy concurrent kidney of hydronephrosis.Patient is often asymptomatic over a long time, until just noted when there is abdominal mass and the swollen sense of waist.Lump is many inadvertently to be found, generally has cystic sense.Pain is general comparatively light, even completely painless.But can renal colic be there is, sharp ache, along costal margin, ureter traveling radiation in intermittent hydronephrosis case (because ectopic vessel compressing or nephroptosis cause).Many with Nausea and vomiting, abdominal distention, oliguria.Generally alleviate within short time or a few hours, discharge a large amount of urine thereupon.The kidney of increase can be contacted during inspection.As being giant hydronephrosis, its tension force can be not very big.

Medical material present Research involved in the present invention is as follows:

Herba Epimedii [source] this product is the dry aerial parts of Berberidaceae plant Herba Epimedii Epimedium brevicornum Maxim., Epimedium sagittatum Epimedium sagittatum (Sieb.et Zucc.) Maxim., E. Pubescens Epimedium pubescens Maxim., Epimedium wushanense Epimedium wushanense T.S.Ying or Herba Epimedii Epimedium koreanum Nakai.Tap when summer, autumn, stem and leaf was luxuriant, the thick stalk of removing and impurity, dry or dry in the shade.

[process of preparing Chinese medicine] Herba Epimedii: removing impurity, wins blade, and spray clear water, slightly moistens, shredding, dry.[nature and flavor] acrid, sweet, warm.[return through] returns liver, kidney channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.[usage and dosage] 3 ~ 12g.[storage] puts aeration-drying place.

Poria [source] this product is the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.Excavate more than 7 ~ JIUYUE, dig out rear removing silt, bank up after " diaphoresis ", spread out and dry in the air to dry tack free, then " diaphoresis ", after extremely now scatter and disappear in wrinkle, the large portion of internal moisture for several times repeatedly, dry in the shade, be called " Poria "; Or fresh Poria is pressed different parts cutting, dry in the shade, be called " Cortex Sclerotii Poriae " and " Poria block ".[process of preparing Chinese medicine] gets Poria, soaks, and cleans, slightly steams, cut skin and block in time or cut sheet, drying after profit.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.

[usage and dosage] 6 ~ 15g.[storage] puts dry place, moistureproof.

Rhizoma Alismatis [source] this product is the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis Alisma orientalis (Sam.) Juzep..Excavate when winter, stem and leaf started withered, cleaning, drying, removing fibrous root and rough bark.

[process of preparing Chinese medicine] Rhizoma Alismatis: removing impurity, slightly soaks, runs through, cut sheet, dry.[nature and flavor] are sweet, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.[usage and dosage] 6 ~ 9g.[storage] puts dry place, mothproof.

Radix Codonopsis [source] this product is the dry root of Campanulaceae Radix Codonopsis Codonopsis pilosula (Franch.) Nannf., element flower Radix Codonopsis (RADIX CODONOPSIS PILOSULAE from Northwest of China) Codonopsis pilosula Nannf. var. modesta (Nannf.) L. T. Shen or radix codonpsis tangshen Codonopsis tangshen Oliv..Autumn excavates, and cleans, dries.[process of preparing Chinese medicine] removing impurity, cleans, runs through, cut sheet, dry.

[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.

[usage and dosage] 5 ~ 30g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.[storage] puts aeration-drying place.Mothproof.

Summary of the invention

The present invention aims to provide one and is used for the treatment of hydronephrotic medicine, by selecting suitable medical material and proportioning thereof, reaches the safe and effective object being applied to Kidney hydrocele.

In order to achieve the above object, the present invention is by the following technical solutions:

One is used for the treatment of hydronephrotic medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Epimedii 10 parts, 8 parts, Poria, Rhizoma Alismatis 6 parts, Radix Codonopsis 5 parts.

Inventor is according to the Couple herbs that has the deep influence of a scholarly family, and think that the traditional Chinese medical science is thought, waist is the internal organs of kidney, soreness of waist distending pain when duty in kidney.Is just deficiency of kidney-QI, the not main water of kidney, folding is had no right, then kidney insufficiency, and insufficiency of kidney-YANG can not warm kidney yin, and deficiency of the kidney yin can not nourish kidney yang, causes in water liquid and stops and the hydronephrosis that arrives.Control suitable nourishing YIN supporing yang, activating QI to promote diuresis.Herba Epimedii in side, acrid, sweet, warm, return liver, kidney channel, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Poria, GUIXIN, lung, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; Rhizoma Alismatis, returns kidney, urinary bladder channel, diuresis, clearing away damp-heat; Radix Codonopsis, returns spleen, lung meridian, invigorating the spleen and replenishing QI.All medicines share, effect that common performance warming YANG activating QI, diuretic dry.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

In JIUYUE, 2012 collects hydronephrotic patient 160 example in June ,-2014, is divided into 2 groups at random.Treatment group man 46 example, female 34 example, age 19-65 year, 42.5 years old mean age, the course of disease 2 days-3 months; Matched group man 44 example, female 36 example, age 18-62 year, 40.5 years old mean age, the course of disease 1 day-3 months.There is not exception in the renal function of two groups of patients.Compare the sex of two groups of patients, age and the course of disease, there is not significant difference, there is comparability.

2, diagnostic criteria

1. B ultrasonic, IVU or diuretic kidney figure confirm upper urinary, merge hydronephrosis.2. IVU shows that the development of Ipsilateral kidney postpones or do not develop, or radioactive renogram shows impaired renal function or nonfunctional.3. blood BUN, Cr is all normal.4. the disease causing decreased renal function is got rid of.

3, research method

3.1 Therapeutic Method

Treatment group takes the decoct that the present invention obtains according to specific embodiment 1, and every bu morning, noon and afternoon take for three times.

Matched group oral amoxicillin associating furosemide, takes according to its description.

All treat 2 weeks for two groups.

Meals are taken good care of oneself: light, easy to digest, less salt, low fat, restriction take in albumen quality, edible protein is based on animal proteinum, avoid excessively restriction that malnutrition edema serious patient occurs to need to lie up, other symptomatic treatments actively prevent complication and infection control simultaneously.

3.2 statistical method

Adopt SPSS18.0 statistics software data processing.

4, therapeutic outcome

4.1 criterion of therapeutical effect

Recovery from illness: transference cure, B ultrasonic or renal phlebography, CT are checked hydronephrosis and are disappeared;

Take a turn for the better: remission, B ultrasonic or renal phlebography, CT are checked hydronephrosis and are obviously reduced;

Invalid: before and after treatment, symptom has no improvement, even exacerbation of symptoms.

3.2 liang of group curative effects

In 80 routine patients of matched group, 12 examples be completely recovered, 60 examples of improvement, 8 invalid examples, cure rate is 15%, and total effective rate is 90%; In treatment group, patient 25 example of recovery from illness, 52 examples of improvement, 3 invalid examples, cure rate is 31.3%, and total effective rate is 96.25%.Two groups of cure rates compare, and there is significant significant difference, P<0.05, and the cure rate for the treatment of group is significantly higher than matched group; There is not significant difference in two groups of total effective percentage.

Visible, the medicine that the present invention obtains can safe and effective treatment hydronephrosis, has good medical science promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Herba Epimedii 10 grams, 8 grams, Poria, Rhizoma Alismatis 6 grams, Radix Codonopsis 5 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of hydronephrosis.Oral, every bu morning, noon and afternoon take for three times.

Embodiment 2

Take: Herba Epimedii 10 grams, 8 grams, Poria, Rhizoma Alismatis 6 grams, Radix Codonopsis 5 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of hydronephrosis.Oral, daily once.

Embodiment 3

Take: Herba Epimedii 10 grams, 8 grams, Poria, Rhizoma Alismatis 6 grams, Radix Codonopsis 5 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of hydronephrosis.Oral, every bu is taken for twice sooner or later.

Claims

1. be used for the treatment of a hydronephrotic medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Epimedii 10 parts, 8 parts, Poria, Rhizoma Alismatis 6 parts, Radix Codonopsis 5 parts.