CN102895521B - Traditional Chinese medicine for treating ankylosing spondylitis - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating ankylosing spondylitis. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: 8 parts of Codonopsis pilosula, 6 parts of radix astragali, 15 parts of dioscorea opposita, 12 parts of pericarpium citri reticulatae, 9 parts of root of Chinese thorowax, 6 parts of poria, 9 parts of lucid ganoderma, 6 parts of cortex cinnamomi, 5 parts of snow saussurea, 5 parts of cynomorium songaricum, 5 parts of morinda officinalis, 5 parts of semen cuscutae chinensis, 12 parts of angelica sinensis, 10 parts of polygonum multiflorum, 10 parts of white paeony root, 10 parts of asparagus cochinchinensis and 10 parts of rhizoma polygonati odorati. Clinical experiments show that the traditionalChinese medicine can safely and effectively treat ankylosing spondylitis.

Description

A kind of traditional Chinese medicine for treating ankylosing spondylitis

technical field

The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating ankylosing spondylitis.

Background technique

Ankylosing spondylitis (AS) is a chronic inflammatory disease that mainly invades sacroiliac joints, spinal condyles, paraspinal soft tissues and peripheral joints, and may be accompanied by extra-articular manifestations. The main clinical manifestations are waist, back, neck, buttock, hip pain and joint swelling and pain. In severe cases, spinal deformity and joint ankylosis may occur. The onset group is 10 to 40 years old, and the average onset age is 25 years old. Men are more common than women. There is no cure for AS yet. However, if the patients can be diagnosed in time and treated reasonably, the symptoms can be controlled and the prognosis can be improved.

For ankylosing spondylitis, there is still a lack of recognized safe and effective treatment drugs.

The research status of the medicinal materials involved in Chinese medicine of the present invention is as follows:

Codonopsis [source] Codonopsis Codonopsis is a perennial herb of Campanulaceae. [Functions and Indications] It has the effects of invigorating the middle and replenishing Qi, strengthening the spleen and lungs. Enhance immunity, dilate blood vessels, reduce blood pressure, improve microcirculation, enhance hematopoietic function, etc.

Astragalus [source] is the root of the leguminous plant Astragalus mongolica or Astragalus membranaceus. Remove fibrous root and root head, sun-dried, sliced, used raw or broiled with honey. [Functions and Indications] It can enhance the immune function of the body, protect the liver, diuretic, anti-aging, anti-stress, lower blood pressure and have a wide range of antibacterial effects.

Yam 【Source】 Perennial herb with vines, often purple, cylindrical root, opposite leaves, ovate or oval, milky white flowers, dioecious. Root tubers contain starch and protein. [Functions and Indications] Tonify the spleen and nourish the stomach, promote body fluid and benefit the lung, tonify the kidney and astringent essence. Used for insufficiency of the spleen, lack of food, persistent diarrhea, dyspnea and cough due to lung deficiency, spermatorrhea due to kidney deficiency, leukorrhea, frequent urination, deficiency-heat and quenching thirst. the

Chenpi [source] the mature peel of Rutaceae plant Tangerine and its cultivars. [Functions and Indications] Regulating qi and appetizing, drying dampness and resolving phlegm, and treating spleen and stomach diseases.

Bupleurum [source] Alias: Cihu, Dixun, traditional Chinese medicine for clearing deficiency and heat. [Functions and Indications] Expelling the surface to expel heat, soothing the liver and relieving stagnation, elevating yang qi.

Poria cocos [source] is a fungus plant that parasitizes on the roots of pine trees. It is shaped like a sweet potato. [Functions and Indications] Sweet in taste, light in taste, flat in nature, used as medicine has the functions of diuresis and expelling dampness, benefiting spleen and stomach, calming the mind and calming the nerves. It can enhance the immune function of the body. Poria cocos polysaccharide has obvious anti-tumor and liver-protecting effects.

Ganoderma lucidum [source] the dry fruiting body of the fungus Chizhi or Zizhi of the family Poraceae. Ganoderma lucidum used as medicine is red lucidum and purple lucidum, and its medicinal properties are sweet and flat. [Functions and Indications] Enhance human immunity, regulate blood sugar, control blood pressure, assist tumor radiotherapy and chemotherapy, protect liver and liver, promote sleep, etc. It can regulate the body's immune function, effectively inhibit tumor growth and cell mutation, delay aging, resist fatty liver, regulate blood lipid and blood sugar, and promote hematopoietic function.

Cinnamon 【Source】The dried bark of Cinnamomum cassia Presl, a plant of Lauraceae, is hot in nature, pungent and sweet in taste. [Functions and Indications] Replenishing fire and supporting yang, drawing fire back to its source, dispelling cold and relieving pain, promoting blood circulation and stimulating menstruation. Warm the spleen and stomach, remove accumulated cold, and clear blood vessels. Treatment of fire failure at the door of life, cold extremities and weak pulse, loss of yang and prostration, abdominal pain and diarrhea, cold hernia, cold pain in the waist and knees, amenorrhea, gangrene, bleeding, and deficiency of yang, upper heat and lower cold .

Snow Lotus 【Origin】Qiaguo Suba in Tibetan, is a perennial herb of Compositae, a world-renowned rare Tibetan medicine. Harvest when blooming between June and July, pull up the whole plant, remove the sediment, and dry in the air. [function cures mainly] removes cold, strengthens yang, regulates menstruation, stops bleeding. Treatment of impotence, weakness of the waist and knees, collapse of the belt in women, irregular menstruation, rheumatoid arthritis, traumatic bleeding.

Cynomorium [source] Also known as elixir, it is a perennial succulent parasitic herb. The underground stem is thick and short, with many tumorous absorption roots. It grows wild in the Gobi desert, where there is no snow and the ground is not frozen. [Functions and Indications] It has the effects of invigorating the kidney and moistening the intestines, treating impotence and hematuria.

Morinda officinalis [source] is the dried root of Morinda officinalis How. [Functions and Indications] Indications for impotence and nocturnal emission, uterine cold and infertility, irregular menstruation, cold pain in the lower abdomen, rheumatic arthralgia, muscle and bone flaccidity and weakness. the

Cuscuta [source] the seeds of dicotyledonous plant medicine Convolvulaceae, Cuscuta, southern dodder, and golden vine. [Functions and Indications] It has the effects of invigorating the kidney and essence, nourishing the liver and improving eyesight, strengthening the fetus and stopping leakage.

Angelica [source] Scientific name: Angelica sinensis, perennial herb with purple stems. Cultivated everywhere. The root can be used as medicine and is one of the most commonly used traditional Chinese medicines. [Functions and Indications] Anti-hypoxia, regulation of immune function, anti-cancer, skin care and beauty, nourishing and promoting blood circulation, antibacterial, anti-arteriosclerosis

Polygonum multiflorum [source] is a perennial twining vine of Polygonaceae. The root is slender, and the end becomes a hypertrophic root tuber, and the appearance is reddish brown to dark brown. The roots, canes and leaves of the plant are all available for medicinal purposes. [Functions and Indications] Detoxification, loosening bowels, eliminating carbuncles; nourishing essence and blood, black beard and hair, strengthening muscles and bones, nourishing liver and kidney. Promote hematopoietic function and enhance immune function. the

Radix Paeoniae Alba [Source] is the root of the dicotyledonous plant Paeoniae officinalis (cultivated species). Peony roots that have been planted for 3 to 4 years, remove the rhizomes and fibrous roots, wash, scrape off the rough skin, boil in boiling water for a while to make the peony roots soft, take them out and dry them in the sun. [Functions and Indications] Nourishing blood and softening the liver, relieving pain in the middle, astringing yin and sweating. Control chest and abdomen hypochondriac pain, dysentery abdominal pain, spontaneous sweating, night sweats, and fever due to deficiency of YIN.

Asparagus [source] Liliaceae plants. Also known as asparagus. Cold in nature, sweet in taste, slightly bitter. It has the effects of nourishing yin and clearing away heat, nourishing the lungs and nourishing the kidneys. [Functions and Indications] It is used to treat diseases such as yin deficiency and fever, cough and hematemesis, pulmonary abscess, sore throat, thirst, and constipation. the

Polygonatum [source] is a perennial herb of Liliaceae. The rhizome is horizontal, the flesh is yellowish white, and most of the fibrous roots are densely grown. Dried in the sun, or steamed thoroughly, kneaded until translucent, dried in the sun, cut into thick slices or segments for use. [Functions and Indications] Nourishing yin and nourishing the lungs; nourishing the stomach and promoting body fluid. Dry cough; fatigue cough; febrile disease, dry throat and thirst caused by yin fluid consumption; internal heat and thirst; yin deficiency and external sensation; dizziness and dizziness;

Contents of the invention

The invention aims to provide a traditional Chinese medicine for treating ankylosing spondylitis, which can safely and effectively cure ankylosing spondylitis by selecting appropriate medicinal materials and their proportions.

In order to achieve the above object, the present invention adopts the following technical solutions:

A traditional Chinese medicine for treating ankylosing spondylitis, which is characterized in that it is prepared from the following medicinal materials in weight proportions: 8 parts of Codonopsis pilosula, 6 parts of Astragalus membranaceus, 15 parts of Chinese yam, 12 parts of tangerine peel, 9 parts of Bupleurum, 6 parts of Poria cocos, 9 parts of ganoderma lucidum, 6 parts of cinnamon, 5 parts of snow lotus, 5 parts of cynomorium, 5 parts of Morinda officinalis, 5 parts of dodder seed, 12 parts of angelica, 10 parts of Polygonum multiflorum, 10 parts of white peony root, 10 parts of asparagus, 10 parts of Polygonatum odoratum .

Below in conjunction with clinical experiment data illustrate the beneficial effect of the present invention:

1. General information

The inventor collected 80 outpatients with ankylosing spondylitis from June 2010 to September 2011, aged 12-47 years, and the course of disease was 0.5-7 years. Randomly divided into: a treatment group of 50 cases, a blank group of 30 cases. There was no significant difference in age, condition and other data between the two groups, and they were comparable. the

2. Test method

2.1 The treatment group took orally the capsules prepared according to Embodiment 1 of the present invention, once in the morning and in the evening. The course of treatment is 30 days.

2.2 The blank group took placebo capsules orally, once in the morning and in the evening. The course of treatment is 30 days.

3. Efficacy criteria and treatment results

3.1 Curative effect standard

Recovery from illness: all clinical symptoms disappeared, and the laboratory examination was normal. Improvement: the clinical symptoms are alleviated, the condition is under control, and the laboratory tests are improved or normal. Ineffective: no obvious improvement or aggravation of clinical symptoms.

3.2 See Table 1 for the statistical results of treatment.

Table 1 Comparison of curative effect between the two groups

group no get well get better invalid Total effective rate (%) therapy group 50 10 (20%) 34 (68%) 6 (12%) 88% blank group 30 0 5 (16.7%) 25 (83.3%) 16.7%

It can be seen that the medicine prepared by the present invention can safely and effectively treat ankylosing spondylitis.

Detailed ways

In order to better understand and implement the present invention, the present invention will be further described below in conjunction with specific examples.

Specific embodiment 1

Weighing: Codonopsis 8 grams, Astragalus 6 grams, Chinese yam 15 grams, orange peel 12 grams, Bupleurum 9 grams, Poria cocos 6 grams, Ganoderma lucidum 9 grams, cinnamon 6 grams, snow lotus 5 grams, Cynomorium 5 grams, Morinda officinalis 5 grams gram, 5 grams of dodder, 12 grams of angelica, 10 grams of Polygonum multiflorum, 10 grams of white peony, 10 grams of asparagus, 10 grams of Polygonatum odoratum, add 8 times the amount of water, decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct Boil for 1 hour, filter; combine the filtrates, concentrate, dry, and put them into capsule shells to obtain capsules that meet the daily dosage of normal adults.

For the treatment of ankylosing spondylitis. Take it orally, take it twice a day in the morning and evening.

Specific embodiment 2

Weighing: Codonopsis 8 grams, Astragalus 6 grams, Chinese yam 15 grams, orange peel 12 grams, Bupleurum 9 grams, Poria cocos 6 grams, Ganoderma lucidum 9 grams, cinnamon 6 grams, snow lotus 5 grams, Cynomorium 5 grams, Morinda officinalis 5 grams gram, 5 grams of dodder, 12 grams of angelica, 10 grams of Polygonum multiflorum, 10 grams of white peony, 10 grams of asparagus, 10 grams of Polygonatum odoratum, add 8 times the amount of water, decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct Boil for 1 hour, filter; combine the filtrates, concentrate, dry, concentrate, dry, and pulverize to obtain a powder that meets the daily dosage of a normal adult.

For the treatment of ankylosing spondylitis. Take it orally, take it twice a day in the morning and evening.

Specific embodiment 3

Weighing: Codonopsis 8 grams, Astragalus 6 grams, Chinese yam 15 grams, orange peel 12 grams, Bupleurum 9 grams, Poria cocos 6 grams, Ganoderma lucidum 9 grams, cinnamon 6 grams, snow lotus 5 grams, Cynomorium 5 grams, Morinda officinalis 5 grams gram, 5 grams of dodder, 12 grams of angelica, 10 grams of Polygonum multiflorum, 10 grams of white peony, 10 grams of asparagus, 10 grams of Polygonatum odoratum, add 8 times the amount of water, decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct Boil for 1 hour, filter; combine the filtrates, concentrate, dry, and dry, then add appropriate amount of dextrin and flavoring agent, granulate according to the conventional process in this field, and pack to obtain granules that meet the daily dosage of normal adults.

For the treatment of ankylosing spondylitis. Take it orally, take it twice a day in the morning and evening.

Claims (1)

1. A Chinese medicine for the treatment of ankylosing spondylitis, characterized in that it is prepared from the following medicinal materials in weight ratio: 8 parts of Codonopsis radix, 6 parts of Radix Astragali, 15 parts of Chinese yam, 12 parts of tangerine peel, 9 parts of Bupleurum, 6 parts of Poria cocos 9 parts of Ganoderma lucidum, 6 parts of cinnamon, 5 parts of Snow Lotus, 5 parts of Cynomorium, 5 parts of Morinda officinalis, 5 parts of Cuscuta, 12 parts of Angelica, 10 parts of Polygonum multiflorum, 10 parts of white peony root, 10 parts of Asparagus, Polygonatum odoratum 10 servings.