CN104524018A - Medicine for treating dermatophytosis and preparation method of medicine - Google Patents
Medicine for treating dermatophytosis and preparation method of medicine Download PDFInfo
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- CN104524018A CN104524018A CN201410794227.8A CN201410794227A CN104524018A CN 104524018 A CN104524018 A CN 104524018A CN 201410794227 A CN201410794227 A CN 201410794227A CN 104524018 A CN104524018 A CN 104524018A
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- 239000003814 drug Substances 0.000 title claims abstract description 42
- 229940079593 drug Drugs 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 206010012504 Dermatophytosis Diseases 0.000 title abstract 3
- 241001460074 Microsporum distortum Species 0.000 title abstract 3
- 208000002474 Tinea Diseases 0.000 title abstract 3
- 238000004140 cleaning Methods 0.000 claims abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
- 239000007788 liquid Substances 0.000 claims description 21
- 239000010413 mother solution Substances 0.000 claims description 20
- 206010047601 Vitamin B1 deficiency Diseases 0.000 claims description 18
- 208000002894 beriberi Diseases 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 239000012467 final product Substances 0.000 claims description 5
- 239000006210 lotion Substances 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 7
- 235000013399 edible fruits Nutrition 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 abstract description 3
- 240000000233 Melia azedarach Species 0.000 abstract description 2
- 238000001035 drying Methods 0.000 abstract description 2
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 241001180876 Saposhnikovia Species 0.000 abstract 1
- 235000017352 Telosma cordata Nutrition 0.000 abstract 1
- 240000006688 Telosma cordata Species 0.000 abstract 1
- 229940105847 calamine Drugs 0.000 abstract 1
- 229910052864 hemimorphite Inorganic materials 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 238000005303 weighing Methods 0.000 abstract 1
- 235000014692 zinc oxide Nutrition 0.000 abstract 1
- 239000011787 zinc oxide Substances 0.000 abstract 1
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 description 6
- 201000004647 tinea pedis Diseases 0.000 description 6
- 201000004624 Dermatitis Diseases 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 4
- 208000010668 atopic eczema Diseases 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 210000002683 foot Anatomy 0.000 description 3
- 206010023126 Jaundice Diseases 0.000 description 2
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 description 2
- 241000223238 Trichophyton Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
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- 244000045947 parasite Species 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000008736 traumatic injury Effects 0.000 description 2
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 241000219317 Amaranthaceae Species 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
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- 208000006820 Arthralgia Diseases 0.000 description 1
- 240000005343 Azadirachta indica Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000125183 Crithmum maritimum Species 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 240000004859 Gamochaeta purpurea Species 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010024229 Leprosy Diseases 0.000 description 1
- 241000244365 Ligusticum sinense Species 0.000 description 1
- 241000158728 Meliaceae Species 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 241000893976 Nannizzia gypsea Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000010195 Onychomycosis Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 244000179560 Prunella vulgaris Species 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 241000246044 Sophora flavescens Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 244000137773 Viola philippica Species 0.000 description 1
- 241001106476 Violaceae Species 0.000 description 1
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 230000008952 bacterial invasion Effects 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
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- 238000002651 drug therapy Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 235000020995 raw meat Nutrition 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 206010040882 skin lesion Diseases 0.000 description 1
- 231100000444 skin lesion Toxicity 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 201000005882 tinea unguium Diseases 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine for treating dermatophytosis and a preparation method of the medicine. The medicine is prepared from the following medicinal raw materials in parts by weight: 1.5-13 parts of Chinese violets, 1-8.6 parts of radix sophorae flavescentis, 1-8.6 parts of ligusticum wallichii, 1-8.6 parts of szechwan Chinaberry fruits, 1-8.6 parts of divaricate saposhnikovia roots, 1-8.6 parts of fructus kochiae and 0.5-4 parts of calamine. The preparation method comprises the following steps: weighing the medicinal raw materials in weight proportion; cleaning; drying; crushing; decocting; and concentrating to obtain the medicine. The medicine disclosed by the invention is used for clinically treating dermatophytosis and has the characteristics of good curative effect and small irritation. Among 421 clinical cases, the total effective rate is 97.6%, the efficiency is 93.8% and medication is convenient and rapid.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of medicine for the treatment of beriberi, also relate to the preparation method of this medicine simultaneously.
Background technology
Beriberi is the popular name of tinea pedis, and be a kind of common fungal infection dermatoses, betide the skin between sufficient sole of the foot portion and toe, be mainly in adult, the whole world is popular.
The skin lesion of beriberi has a feature, i.e. clear border, can gradually to external expansion.Because of PD or scratch, erosion, sepage can be there is, even bacteriological infection, occur pustule etc.
In tinea pedis morbidity, lacking sebaceous gland and wearing the moist environment that closure shoes cause is most important factor.Be everlasting and increase the weight of summer, winter alleviates, and also has people not heal all the year round.Tinea pedis seldom causes serious disease or death, but can cause bacillary cellulitis as the door of bacterial invasion, and between toe, type tinea pedis has most high risk, and secondly tinea unguium, is sufficient sole of the foot portion tinea pedis again.
At present, the external used medicine for the treatment of beriberi has a lot, as daktarin, inspire confidence in fine jade, tinea pedis is once held in both hands, golden daktarin, three nine-day periods after the winter solstice choosing spirit, must lie prostrate, and all has certain curative effect, but after treatment easily recurrence, zest greatly, can not fundamentally solve beriberi problem.
In crude drug used in the present invention, Herba Violae (
viola philippica Car) be the whole herb with root of Violaceae Herba Violae or Herba Violae japonicae.Cure mainly jaundice, dysentery, mastitis, conjunctival congestion and swelling pain, pharyngitis external application control traumatic injury, carbuncle, venom etc.
Radix Sophorae Flavescentis (
sophora flavescens) be pulse family Radix Sophorae Flavescentis genus.Heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Rhizoma Chuanxiong (
ligusticum chuanxiong) dry rhizome of samphire Rhizoma Chuanxiong.Cure mainly menoxenia, amenorrhea dysmenorrhea, the stagnant raw meat pain of the stasis of blood in puerperal, lump in the abdomen lump, pain in chest and hypochondrium, has a headache dizzy, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.
Fructus Toosendan be Meliaceae deciduous tree margosa (
melia azedarach Linn) mature fruit.There is the function except damp and hot, clearing away liver-fire, pain relieving, parasite killing.
Radix Saposhnikoviae (
divaricateSaposhnikoviaRoot) be the root of Umbelliferae herbaceos perennial Radix Saposhnikoviae.Expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely.
The Fructus Kochiae (
fructus Kochiae Scopariae) be the mature fruit of chenopod Fructus Kochiae.Clearing away heat-damp and promoting diuresis, diuresis, cure mainly skin eczema, eczema pruritus, dribbling urination, beriberi edema.
Summary of the invention
the object of the present invention is to provide the medicine of a kind of good effect, bland treatment beriberi.
Another object of the present invention is to the preparation method of the medicine that this treatment beriberi is provided.
Medicine of the present invention is prepared by the crude drug of following weight portion:
Herba Violae 1.5-13 part, Radix Sophorae Flavescentis 1-8.6 part, Rhizoma Chuanxiong 1-8.6 part g, Fructus Toosendan 1-8.6 part, Radix Saposhnikoviae 1-8.6 part g, Fructus Kochiae 1-8.6 part, Calamina 0.5-4 part.
Medicine of the present invention can make lotion, and the specification of this lotion is that every 1ml is containing primary crude drug 1g.
A kind of preparation method for the treatment of the medicine of beriberi of the present invention, comprises the following steps:
(1) screen crude drug, sample by weight ratio, cleaning, oven dry, pulverizing;
(2) add crude drug weight 5.5-6.5 water doubly, decoct 4-5 hour, filter, obtain mother solution 1;
(3) add medicinal residues 5.5-6.5 water doubly, decoct 1.5-2 hour, filter, obtain mother solution 2;
(4) mother solution 1, mother solution is 2-in-1 and be concentrated into 1.2 relative density, add ethanol and make alcohol content be 60%, obtain medicinal liquid 3;
(5) medicinal liquid 3 is left standstill 24 hours, filter, reclaim ethanol, obtain medicinal liquid 4;
(6) regulated by medicinal liquid 4 alcohol content to be 30% and get final product.
The present invention compared with prior art, there is obvious beneficial effect, as can be known from the above technical solutions: the present invention selects Herba Violae, Radix Sophorae Flavescentis, Rhizoma Chuanxiong, Fructus Toosendan, Radix Saposhnikoviae, the Fructus Kochiae, Calamina to be raw material, beriberi is treated by the synergism of each medicine, effectively can suppress the activity of trichophyton, trichophyton gypseum, acrothesium floccosum, trichophyton meginii etc., external use anti pruritic pain relieving, thus alleviate sufficient moss infection place skin itch, erosion, reduce scurf and formed.Its expense is low, good effect, side effect are little, and medication is convenient and swift.Clinical 421 examples use, total effective rate 97.6%, obvious effective rate 93.8%.
Detailed description of the invention
the beneficial effect of medicine of the present invention is set forth further below by way of test example.
test example:the clinical observation of medicine of the present invention
Clinical data:
All cases 421 example, wherein male 298 example, women 123 example, max age 82 years old, minimum 14 years old.
Diagnostic criteria:
" disease of tcm Standardization of diagnosis and curative effect "
Therapeutic Method:
The 1:2 foot bath 20 minutes in proportion of each medicinal liquid and warm water, or directly dipping in former medicine with special cotton swab embrocates lesions position, every day 1-2 time, 3 a little.
Criterion of therapeutical effect:
Effective: transference cure
Effective: symptom is obviously alleviated
Invalid: symptom is without improvement or increase the weight of.
Therapeutic outcome:
421 routine patients are through Drug therapy of the present invention, and effective 395 examples, effective 16 examples, invalid 10 is routine, total effective rate 97.6%.
embodiment 1
Treat a medicine for beriberi, comprise the following steps:
(1) Herba Violae 1.5g is taken, Radix Sophorae Flavescentis 8.6, Rhizoma Chuanxiong 1g, Fructus Toosendan 8.6g, Radix Saposhnikoviae 8.6g, Fructus Kochiae 1g, Calamina 4g, cleaning, oven dry, pulverizing;
(2) add the water of crude drug weight 6 times, decoct 4.5 hours, filter, obtain mother solution 1;
(3) add the water of medicinal residues 6 times, decoct 1.5 hours, filter, obtain mother solution 2;
(4) mother solution 1, mother solution is 2-in-1 and be concentrated into 1.2 relative density, add ethanol and make alcohol content be 60%, obtain medicinal liquid 3;
(5) medicinal liquid 1 is left standstill 24 hours, reclaim ethanol, obtain medicinal liquid 4;
(6) regulated by medicinal liquid 4 alcohol content to be 30% and get final product.
embodiment 2
Treat a medicine for beriberi, comprise the following steps:
(1) Herba Violae 13g is taken, Radix Sophorae Flavescentis 1g, Rhizoma Chuanxiong 8.6g, Fructus Toosendan 1g, Radix Saposhnikoviae 1g, Fructus Kochiae 8.6g, Calamina 0.5g, cleaning, oven dry, pulverizing;
(2) add the water of crude drug weight 6.5 times, decoct 5 hours, filter, obtain mother solution 1;
(3) add the water of medicinal residues 5.5 times, decoct 2 hours, filter, obtain mother solution 2;
(4) mother solution 1, mother solution is 2-in-1 and be concentrated into 1.2 relative density, add ethanol and make alcohol content be 60%, obtain medicinal liquid 3;
(5) medicinal liquid 1 is left standstill 24 hours, reclaim ethanol, obtain medicinal liquid 4;
(6) regulated by medicinal liquid 4 alcohol content to be 30% and get final product.
embodiment 3
Treat a medicine for beriberi, comprise the following steps:
(1) Herba Violae 9.5g is taken, Radix Sophorae Flavescentis 4.5g, Rhizoma Chuanxiong 6g, Fructus Toosendan 5.5g, Radix Saposhnikoviae 4g, Fructus Kochiae 5g, Calamina 2g, cleaning, oven dry, pulverizing;
(2) add the water of crude drug weight 5.5 times, decoct 4 hours, filter, obtain mother solution 1;
(3) add the water of medicinal residues 6.5 times, decoct 1.75 hours, filter, obtain mother solution 2;
(4) mother solution 1, mother solution is 2-in-1 and be concentrated into 1.2 relative density, add ethanol and make alcohol content be 60%, obtain medicinal liquid 3;
(5) medicinal liquid 1 is left standstill 24 hours, reclaim ethanol, obtain medicinal liquid 4;
(6) regulated by medicinal liquid 4 alcohol content to be 30% and get final product.
Claims (4)
1. treat a medicine for beriberi, be made up of the crude drug of following weight parts: Herba Violae 1.5-13 part, Radix Sophorae Flavescentis 1-8.6 part, Rhizoma Chuanxiong 1-8.6 part g, Fructus Toosendan 1-8.6 part, Radix Saposhnikoviae 1-8.6 part g, Fructus Kochiae 1-8.6 part, Calamina 0.5-4 part.
2. the medicine for the treatment of beriberi as claimed in claim 1, is characterized in that: described medicine is lotion.
3. the medicine for the treatment of beriberi as claimed in claim 2, is characterized in that: the specification of described lotion is that every 1ml lotion is containing primary crude drug 1g.
4. the preparation method of the medicine for the treatment of beriberi as claimed in claim 1, comprises the following steps:
(1) screen crude drug, sample by weight ratio, cleaning, oven dry, pulverizing;
(2) add crude drug weight 5.5-6.5 water doubly, decoct 4-5 hour, filter, obtain mother solution 1;
(3) add medicinal residues 5.5-6.5 water doubly, decoct 1.5-2 hour, filter, obtain mother solution 2;
(4) mother solution 1, mother solution is 2-in-1 and be concentrated into 1.2 relative density, add ethanol and make alcohol content be 60%, obtain medicinal liquid 3;
(5) medicinal liquid 3 is left standstill 24 hours, filter, reclaim ethanol, obtain medicinal liquid 4;
(6) regulate alcohol content to be 30% to medicinal liquid 4 and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410794227.8A CN104524018A (en) | 2014-12-21 | 2014-12-21 | Medicine for treating dermatophytosis and preparation method of medicine |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410794227.8A CN104524018A (en) | 2014-12-21 | 2014-12-21 | Medicine for treating dermatophytosis and preparation method of medicine |
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| Publication Number | Publication Date |
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| CN104524018A true CN104524018A (en) | 2015-04-22 |
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| CN201410794227.8A Pending CN104524018A (en) | 2014-12-21 | 2014-12-21 | Medicine for treating dermatophytosis and preparation method of medicine |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1096213A (en) * | 1994-01-24 | 1994-12-14 | 史建华 | Athlete's foot washing liquid and preparation method thereof |
| CN101084988A (en) * | 2007-06-19 | 2007-12-12 | 沙宝瑜 | Medicine for treating foot diseases and insole containing the said medicine |
| CN102366560A (en) * | 2011-09-21 | 2012-03-07 | 吴江市顺昌日用品有限公司 | Spray for beriberi and preparation method thereof |
| CN102988751A (en) * | 2012-10-30 | 2013-03-27 | 严中明 | Traditional Chinese medicine composition for treating beriberi and preparation method thereof |
| CN103070964A (en) * | 2013-01-12 | 2013-05-01 | 王理林 | Spring healthcare foot washing solution and preparation method thereof |
| CN103735652A (en) * | 2014-01-02 | 2014-04-23 | 许伟 | Traditional Chinese medicine for treating beriberi |
-
2014
- 2014-12-21 CN CN201410794227.8A patent/CN104524018A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1096213A (en) * | 1994-01-24 | 1994-12-14 | 史建华 | Athlete's foot washing liquid and preparation method thereof |
| CN101084988A (en) * | 2007-06-19 | 2007-12-12 | 沙宝瑜 | Medicine for treating foot diseases and insole containing the said medicine |
| CN102366560A (en) * | 2011-09-21 | 2012-03-07 | 吴江市顺昌日用品有限公司 | Spray for beriberi and preparation method thereof |
| CN102988751A (en) * | 2012-10-30 | 2013-03-27 | 严中明 | Traditional Chinese medicine composition for treating beriberi and preparation method thereof |
| CN103070964A (en) * | 2013-01-12 | 2013-05-01 | 王理林 | Spring healthcare foot washing solution and preparation method thereof |
| CN103735652A (en) * | 2014-01-02 | 2014-04-23 | 许伟 | Traditional Chinese medicine for treating beriberi |
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