CN104523932B - A kind of Chinese medicine composition for treating children's hyperkinetic syndrome, and its preparation method and application - Google Patents
A kind of Chinese medicine composition for treating children's hyperkinetic syndrome, and its preparation method and application Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of Chinese medicine composition for treating children's hyperkinetic syndrome and its preparation method and application.The Chinese medicine composition is at least as made by roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn.Present invention also offers the preparation method of the Chinese medicine composition, and its application in treatment children's hyperkinetic syndrome medicine is prepared.Compared with prior art, traditional Chinese medicine composition for treating children's hyperkinetic syndrome of the present invention has the effect of highly significant, and not only efficient high, recurrence rate is low, has no toxic side effect, and prescription is simple, and preparation cost is low, and patient is easy to receive.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for treating children's hyperkinetic syndrome and its preparation method and application, belong to Chinese medicine system
Agent field.
Background technology
Children's hyperkinetic syndrome, also known as attention deficit hyperactivity disorder (ADHD), common class mental handicape childhood being.Table
Be now with age and developmental level be disproportionate absent minded and attention the time is of short duration, hyperactivity hyperkinesia and impulsion, be often accompanied by
Difficulty of learning, conduct disorder and maladjustment.Domestic external survey finds illness rate 3%~7%, and men and women's ratio is 4~9：1.Part
Still there is symptom after infant adult, hence it is evident that family life and sociability after influence patient school work, physically and mentally healthy and adult.Cause
This, the medicine for finding safely and effectively treatment children's hyperkinetic syndrome is most important.
At present, it is emerging using maincenter more than medicine to the treatment typically use psychological intervention combination drug therapy of children's hyperkinetic syndrome
Put forth energy the chemicalses such as agent, selective NRI, although these medicine curative effects are rapid, often with
Based on relief of symptoms, cure the symptoms, not the disease, and usually can be with a series of side reaction, and higher recurrence rate.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating children's hyperkinetic syndrome and its preparation method and application.
For foregoing invention purpose, the present invention provides following technical scheme：
The invention provides a kind of Chinese medicine composition for treating children's hyperkinetic syndrome, it is at least by the raw material system of following parts by weight
Into：10 parts of roxburgh anoectochilus terminal bud, 2-18 parts of loosestrife, 2-18 parts of finger citron flower, 2-18 parts of leaves of Hawthorn.
Preferably, the Chinese medicine composition of described treatment children's hyperkinetic syndrome is at least made up of the raw material of following parts by weight：
10 parts of roxburgh anoectochilus terminal bud, 5-15 parts of loosestrife, 5-15 parts of finger citron flower, 5-15 parts of leaves of Hawthorn.
Be used as it is another preferably, the Chinese medicine composition of described treatment children's hyperkinetic syndrome, it is characterised in that its at least by with
The raw material of lower parts by weight is made：10 parts of roxburgh anoectochilus terminal bud, 10 parts of loosestrife, 10 parts of finger citron flower, 10 parts of leaves of Hawthorn.
It is main to include following step present invention also offers the preparation method of the treatment children's hyperkinetic syndrome Chinese medicine composition
Suddenly：
Roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed, mixes, soaks, decocts, produces；
Or mainly comprise the following steps：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is standby；The mother liquor extracted after volatile oil is standby；Extract after volatile oil
The finger citron flower dregs of a decoction are standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), are added water
Extract, extract solution merges with extracting the mother liquor after volatile oil in step (2), obtains total extract solution；Total extract solution in step (2) with carrying
The volatile oil taken uses cooperatively the Chinese medicine composition as the treatment children's hyperkinetic syndrome.
Preferably, the preparation method of the treatment children's hyperkinetic syndrome Chinese medicine composition mainly comprises the following steps：
Roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed, is mixed, plus 8-12 times of water immersion 0.5-1.5h, decoct 1-3
Secondary, each 1-2h, collecting decoction is produced；
Or mainly comprise the following steps：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is standby；The mother liquor extracted after volatile oil is standby；Extract after volatile oil
The finger citron flower dregs of a decoction are standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), plus 8-
14 times of volume of water, boil extraction 1-3 times, each 1-3 hours, merge extract solution, extract solution in step (2) with extracting after volatile oil
Mother liquor merge, obtain total extract solution；Total extract solution uses cooperatively with the volatile oil extracted in step (2) and is used as the treatment children
The Chinese medicine composition of hyperactivity.
As it is another preferably, the volatile oil can be solidified or with cyclodextrin encapsulated with porous silica.
The present invention finally additionally provides application of the Chinese medicine composition in treatment children's hyperkinetic syndrome medicine is prepared.
Preferably, the Chinese medicine composition is made into oral formulations according to conventional formulation method.
As it is another preferably, the oral formulations be tablet, capsule, oral liquid, granule, powder, pill or drop
Pill
The above-mentioned Chinese medicine composition of the present invention adds required various customary adjuvants when preparing different dosage forms, for example, dilute
Agent, binder, disintegrant, glidant, lubricant, flavouring, inclusion material, sorbing material etc. are prepared with conventional formulation method
Into the oral formulations that any one is conventional, for example, can be granule, powder, tablet, capsule, pill, oral liquid, pill
Deng.
The present invention the Chinese medicine composition principles of formulating prescriptions be：In side roxburgh anoectochilus terminal bud and loosestrife strengthen the body resistance to consolidate the constitution, clearing heat and cooling blood peace
Weigh negative and positive, main ingredient in the side of being.Assistant is with leaves of Hawthorn and finger citron flower invigorating the spleen dissolving stasis, dispersing stagnated hepatoqi.All medicines share, plays nourishing and suppressing Yang altogether,
Allay excitement the work(of intelligence development.It is mainly used in children ADHD, seeing has notice to lax, moves multi-lingual, impulsion is wilful, difficulty of learning, tongue more
Matter is red, the deficiency of the kidney yin such as thready rapid pulse, excess of liver-YANG,dominance of liver-YANG person.
Beneficial effects of the present invention are mainly：
The traditional Chinese medicine composition for treating children's hyperkinetic syndrome of the present invention has the effect of highly significant, not only efficient high, recurrence
Rate is low, has no toxic side effect, and prescription is simple, and preparation cost is low, and patient is easy to receive.
Embodiment
With reference to embodiment, the present invention is described in further detail, but should be noted that the scope of the present invention not by this
Any limitation of a little examples.
Embodiment 1
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 2g, finger citron flower 2g, leaves of Hawthorn 2g
Preparation method：
Add 8 times of amount water to soak 0.5 hour above-mentioned medicinal material, decoct 1 time, 3 hours every time, collecting decoction was produced.
Usage and consumption：One portion per day.
Embodiment 2
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 18g, finger citron flower 18g, leaves of Hawthorn 18g
Preparation method：
Add 12 times of amount water to soak 1.5 hours above-mentioned medicinal material, decoct 3 times, 1 hour every time, collecting decoction was produced.
Usage and consumption：One portion per day.
Embodiment 3
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 10g, finger citron flower 10g, leaves of Hawthorn 10g
Preparation method：
Add 10 times of amount water to soak 1 hour above-mentioned medicinal material, decoct 2 times, 1.5 hours every time, collecting decoction was produced.
Usage and consumption：One portion per day.
Embodiment 4
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 2g, finger citron flower 2g, leaves of Hawthorn 2g
Preparation method：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is standby；The mother liquor extracted after volatile oil is standby；Extract after volatile oil
The finger citron flower dregs of a decoction are standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), plus 8 times
Volume of water, boils extraction 1 time, 3 hours every time, merges extract solution, extract solution is closed with extracting the mother liquor after volatile oil in step (2)
And, obtain total extract solution；
Total extract solution centrifugal filtration, filtrate is condensed into thick paste, thick paste is mixed with dextrin, and particle is made, and dries, by particle
It is well mixed with volatile oil, talcum powder, magnesium stearate obtained by step (2), tabletting produces tablet.
Embodiment 5
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 18g, finger citron flower 18g, leaves of Hawthorn 18g
Preparation method：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is standby；The mother liquor extracted after volatile oil is standby；Extract after volatile oil
The finger citron flower dregs of a decoction are standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), plus 14
Times volume of water, boils extraction 3 times, 1 hour every time, merges extract solution, extract solution is with extracting the mother liquor after volatile oil in step (2)
Merge, obtain total extract solution；
Total extract solution centrifugal filtration, filtrate is condensed into thick paste, with volatile oil, the polyethylene glycol melted obtained by step (2)
4000 are well mixed, and dripping pill is made in drop, produces pill.
Embodiment 6
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 10g, finger citron flower 10g, leaves of Hawthorn 10g
Preparation method：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is included with hydroxypropyl-β-cyclodextrin, standby；Extract the mother after volatile oil
Liquid is standby；The finger citron flower dregs of a decoction extracted after volatile oil are standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), plus 11
Times volume of water, boils extraction 2 times, 2 hours every time, merges extract solution, extract solution is with extracting the mother liquor after volatile oil in step (2)
Merge, obtain total extract solution；
Total extract solution centrifugal filtration, filtrate is condensed into thick paste, by hydroxypropyl-β-cyclodextrin bag obtained by thick paste and step (2)
The volatile oil of conjunction, appropriate dextrin and Icing Sugar mixing, are made particle, dry, that is, granule is made.
Embodiment 7
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 5g, finger citron flower 5g, leaves of Hawthorn 5g
Preparation method：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is solidified with porous silica, standby；Extract the mother liquor after volatile oil
It is standby；The finger citron flower dregs of a decoction extracted after volatile oil are standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), plus 10
Times volume of water, boils extraction 2 times, 2 hours every time, merges extract solution, extract solution is with extracting the mother liquor after volatile oil in step (2)
Merge, obtain total extract solution；
Total extract solution centrifugal filtration, filtrate is condensed into thick paste, thick paste is mixed with dextrin, and particle is made, and dries, by particle
It is well mixed with volatile oil, talcum powder, the magnesium stearate of porous silica solidification obtained by step (2), tabletting produces tablet.
Embodiment 8
Prescription：Roxburgh anoectochilus terminal bud 10g, loosestrife 15g, finger citron flower 15g, leaves of Hawthorn 15g
Preparation method：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is standby；The mother liquor extracted after volatile oil is standby；Extract after volatile oil
The finger citron flower dregs of a decoction are standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), plus 12
Times volume of water, boils extraction 2 times, 2 hours every time, merges extract solution, extract solution is with extracting the mother liquor after volatile oil in step (2)
Merge, obtain total extract solution；
Total extract solution centrifugal filtration, concentration, plus ethanol to ethanol content reach 60%, and alcohol precipitation 48 hours takes supernatant to return
Ethanol is received, volatile oil and suitable quantity of water obtained by step (2) is added, activated carbon decolorizing, filtering is dispensed into oral liquid bottle, sterilizing, i.e.,
Obtain oral liquid.
The clinical drug therapeutic effect of the present invention of embodiment 9
(1) general information
Yangtze river in nanjing hospital clinical case, chooses children's hyperkinetic syndrome patient totally 180, is randomly divided into four treatment groups and one
Individual control group, every group 36.Every group of sex, age, course of disease etc. are statistically analyzed, no significant difference (P>O.05),
With comparativity.
(2) treatment method
1. control group not drug administration, only according to doctor's advice, carries out conventional psychotherapy and family therapy.
2. therapeutic component is 1 group for the treatment of, treats 2 groups, 3 groups and 4 groups for the treatment of treated, on the basis of control group treatment method
On, the Chinese medicine composition as obtained by the embodiment of the present invention 3,6,7 and 8 is given respectively.
Usage and consumption：It is 1 consumption obtained by each embodiment, is within 30th a course for the treatment of twice daily.
(3) criterion of therapeutical effect
Effectively：Partial symptoms or symptomatology, alleviate or disappear；
Recurrence：The symptom alleviated after treatment or disappeared, aggravated or occurs again within the 1-3 months.
(4) treatment results
The Chinese medicine composition totall effective rate in clinical treatment of the present invention of table 1 and recurrence rate result (%)
Note：Compared with control group, * P<0.05
In all cases, 3 courses for the treatment of are treated.Treatment results are shown in Table 1, the total effective rate 33.3% for the control group that compares,
The total effective rate of four treatment groups is respectively 72.2%, 69.4%, 75.0% and 69.4%, significantly rise, and difference has statistics
Learn meaning (P<0.05), show that Chinese medicine composition of the present invention is substantially better than control group for children's hyperkinetic syndrome curative effect；
Compare the recurrence rate 22.2% of control group, the recurrence rates of four treatment groups is respectively 8.3%, 11.1%,
11.1% and 8.3%, significantly reduce, the statistically significant (P of difference<0.05), show compared with control group, Chinese medicine of the present invention
Composition can significantly reduce children's hyperkinetic syndrome recurrence rate.
And during treatment, all patients for the treatment of group are showed no obvious adverse reaction, show traditional Chinese medicine composition for treating of the present invention
Children's hyperkinetic syndrome safely and effectively, has no side effect.
Claims (7)
1. a kind of Chinese medicine composition for treating children's hyperkinetic syndrome, it is characterised in that it is made up of the raw material of following parts by weight：Gold thread
10 parts of lotus, 2-18 parts of loosestrife, 2-18 parts of finger citron flower, 2-18 parts of leaves of Hawthorn；
The preparation method of the Chinese medicine composition of the treatment children's hyperkinetic syndrome comprises the following steps：
Roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed, is mixed, plus 8-12 times of water immersion 0.5-1.5h, decoction 1-3 times, often
Secondary 1-2h, collecting decoction is produced；
Or mainly comprise the following steps：
(1) roxburgh anoectochilus terminal bud, loosestrife, finger citron flower and leaves of Hawthorn are weighed；
(2) finger citron flower extracts volatile oil, and volatile oil is standby；The mother liquor extracted after volatile oil is standby；Extract the Buddha's hand after volatile oil
Flower pesticide slag is standby；
(3) roxburgh anoectochilus terminal bud, loosestrife and leaves of Hawthorn are mixed with extracting the finger citron flower dregs of a decoction after volatile oil in step (2), plus 8-14 times
Volume of water, boils extraction 1-3 times, each 1-3 hours, merges extract solution, extract solution is with extracting the mother after volatile oil in step (2)
Liquid merges, and obtains total extract solution；Total extract solution is used cooperatively with the volatile oil extracted in step (2) and moved as the treatment children more
The Chinese medicine composition of disease.
2. the Chinese medicine composition for the treatment of children's hyperkinetic syndrome according to claim 1, it is characterised in that it is by following parts by weight
Raw material be made：10 parts of roxburgh anoectochilus terminal bud, 5-15 parts of loosestrife, 5-15 parts of finger citron flower, 5-15 parts of leaves of Hawthorn.
3. the Chinese medicine composition for the treatment of children's hyperkinetic syndrome according to claim 1, it is characterised in that it is by following parts by weight
Raw material be made：10 parts of roxburgh anoectochilus terminal bud, 10 parts of loosestrife, 10 parts of finger citron flower, 10 parts of leaves of Hawthorn.
4. treatment children's hyperkinetic syndrome Chinese medicine composition according to claim 1, it is characterised in that：The volatile oil is with porous
Silica solidifies or with cyclodextrin encapsulated.
5. application of any one of the claim 1-4 Chinese medicine compositions in treatment children's hyperkinetic syndrome medicine is prepared.
6. application according to claim 5, it is characterised in that：The Chinese medicine composition is made according to conventional formulation method
Oral formulations.
7. application according to claim 6, it is characterised in that：The oral formulations be tablet, capsule, oral liquid,
Granula, powder or pill.
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| 中西医治疗ADHD研究进展;张弛等;《河南中医》;20130430;第33卷(第4期);628-632 * |
| 相修平辨治儿童多动症经验;杨玲、王娣;《辽宁中医杂志》;20071231;第34卷(第10期);1367-1368 * |
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