CN104522461A - Glossy ganoderma peptide rhizoma polygonati polysaccharide and preparation technology thereof - Google Patents
Glossy ganoderma peptide rhizoma polygonati polysaccharide and preparation technology thereof Download PDFInfo
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- CN104522461A CN104522461A CN201410723880.5A CN201410723880A CN104522461A CN 104522461 A CN104522461 A CN 104522461A CN 201410723880 A CN201410723880 A CN 201410723880A CN 104522461 A CN104522461 A CN 104522461A
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- polysaccharide
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- solomonseal rhizome
- siberian solomonseal
- peptide
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- 150000004676 glycans Chemical class 0.000 title claims abstract description 55
- 229920001282 polysaccharide Polymers 0.000 title claims abstract description 55
- 239000005017 polysaccharide Substances 0.000 title claims abstract description 55
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 26
- 241000222336 Ganoderma Species 0.000 title claims abstract description 16
- 238000005516 engineering process Methods 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 238000001035 drying Methods 0.000 claims abstract description 3
- 238000011049 filling Methods 0.000 claims abstract description 3
- 241000756042 Polygonatum Species 0.000 claims description 20
- 235000008737 Polygonatum biflorum Nutrition 0.000 claims description 20
- 241001508722 Urtica fissa Species 0.000 claims description 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 11
- 240000008397 Ganoderma lucidum Species 0.000 claims description 10
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 7
- 238000000855 fermentation Methods 0.000 claims description 5
- 230000004151 fermentation Effects 0.000 claims description 5
- 235000015097 nutrients Nutrition 0.000 claims description 5
- 230000001580 bacterial effect Effects 0.000 claims description 4
- 239000002131 composite material Substances 0.000 claims description 4
- 241000233866 Fungi Species 0.000 claims description 2
- 238000000227 grinding Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 230000008569 process Effects 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 238000000746 purification Methods 0.000 claims description 2
- MSFSPUZXLOGKHJ-UHFFFAOYSA-N Muraminsaeure Natural products OC(=O)C(C)OC1C(N)C(O)OC(CO)C1O MSFSPUZXLOGKHJ-UHFFFAOYSA-N 0.000 claims 1
- 108010013639 Peptidoglycan Proteins 0.000 claims 1
- 239000003053 toxin Substances 0.000 abstract description 4
- 231100000765 toxin Toxicity 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 3
- 241000219422 Urtica Species 0.000 abstract description 2
- 235000009108 Urtica dioica Nutrition 0.000 abstract description 2
- 238000001914 filtration Methods 0.000 abstract description 2
- 235000013305 food Nutrition 0.000 abstract 4
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 238000013329 compounding Methods 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 4
- 230000036541 health Effects 0.000 description 3
- 235000013402 health food Nutrition 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 239000002574 poison Substances 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000015091 medicinal tea Nutrition 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses glossy ganoderma peptide rhizoma polygonati polysaccharide and a preparation technology thereof. The polysaccharide consists of the following components in percentage by weight: 20-60% of glossy ganoderma peptide polysaccharide, 10-50% of rhizoma polygonati polysaccharide and 10-50%, of nettle polysaccharide, and the polysaccharide is prepared through the steps of culturing, filtering, drying, crushing, compounding and filling. The health-care food provided by the invention has obvious effects of expelling toxin, diminishing inflammation and alleviating pain; and in addition, the health-care food also has the efficacies of dispelling wind, removing obstruction in the meridians and regulating nerve centre, the health-care food does not have toxicity, harm or side effects on human bodies, and the health-care food is suitable for sub-health groups.
Description
Technical field:
The present invention relates to a kind of health food with toxin expelling, anti-inflammatory, analgesia effect, particularly a kind of Ganoderma lucidum Peptides Siberian solomonseal rhizome polysaccharide and preparation technology thereof,
Background technology:
Along with the continuous deterioration of people's living environment, more inferior health colony is tending towards youthization, and prevention and the treatment of cancer, severe are faced with, and the habitually medical medicine that the challenge of environmental pollution is original even produces rejection and lost efficacy.
Summary of the invention:
The object of the invention is to overcome above-mentioned deficiency, provide one to have toxin expelling, anti-inflammatory, analgesic health food, successful.In addition, also there is dispelling wind and removing obstruction in the meridians and reconcile neural effect, have no side effect to human non-toxic is harmless.
The object of the present invention is achieved like this, and it is made up of Ganoderma Peptide Polysaccharide, Siberian solomonseal rhizome polysaccharide, polysaccharide from urtica fissa, and its percentage by weight is: Ganoderma Peptide Polysaccharide 20-60%, Siberian solomonseal rhizome polysaccharide 10-50%, polysaccharide from urtica fissa 10-50%.
The concrete preparation technology of Ganoderma Peptide Polysaccharide, Siberian solomonseal rhizome polysaccharide, polysaccharide from urtica fissa is respectively: bacterial classification → inclined-plane cultivate 20 ~ 30 days → Shaking culture, 1 ~ 6 day → fermentation tank culture, 1 ~ 6 day → filter mycelium and refine mycelium → purification polysaccharide → drying → pulverizing in nutrient solution → composite → filling → pack.Cultivate humidity at-2 DEG C ~-4 DEG C, nutrient solution ρ h value is 5---7.8 grinding particle size 80 order---200 orders.The production of Ganoderma lucidum Peptides Siberian solomonseal rhizome polysaccharide is easy to aerobic alcohol and adopts liquid deep layer fermenting technology and large tank collection to fill, and little tank battery is composite to combine.
Described liquid deep layer fermenting technology has aseptic liquid nutrient medium to access bacterial classification in sealed fermentation tank at tank, injects the stirring of filtrated air bottle and ferment.Be characterized in: be easy to heavy industrialization, standardization, automated production, production efficiency is high, quality effectively prevent well each link in conventional method pollution and heavy metals exceeding standard problem.
Ganoderma lucidum Peptides, Siberian solomonseal rhizome polysaccharide be nontoxic, have no side effect, and having changed is the traditional concept of " the good medicine of medicine three points of poison seven points of poison ".This is because intracellular polyse inherently forms the constituent of life cells, and is had by the exocellular polysaccharide that expert is referred to as " sugared quilt " functions such as strengthening immunity.
Ganoderma lucidum Peptides, Siberian solomonseal rhizome polysaccharide can be solids, also can be that liquid is not limited to the forms such as powder, tablet, capsule, granule, pill, medicinal tea.
The mycelium polysaccharides that liquid deep layer fermenting technology is produced, its bioactive ingredients has many kinds, except principle active component fungi polysaccharide, polypeptide, other active ingredient triterpenes, 18 kinds of hincky acids, enzyme, sterol, organic acid, choline, lecithin and trace elements.Large area is improved the audience of inferior health toxin expelling by this.
Glossy ganoderma, sealwort, nettle, due to growing environment restriction, not only yield poorly, biologically active content also there occurs change, particularly the growth cycle of glossy ganoderma is long, by produced in conventional processes, preparation, can not meet the health care demand of tens populations far away.Adopt liquid deep layer fermenting and compounded technology, solve the resource problem of " being medicine three points of poison ", for the mankind benefit!
Detailed description of the invention:
Embodiment one:
The new resources medical-care health food that Ganoderma lucidum Peptides Siberian solomonseal rhizome polysaccharide is made up of Ganoderma Peptide Polysaccharide, Siberian solomonseal rhizome polysaccharide, polysaccharide from urtica fissa, by weight percentage, Ganoderma Peptide Polysaccharide 20%, Siberian solomonseal rhizome polysaccharide 50%, polysaccharide from urtica fissa 30%.
The bacterial classification of Ganoderma Peptide Polysaccharide, Siberian solomonseal rhizome polysaccharide, polysaccharide from urtica fissa through inclined-plane cultivation, Shaking culture, fermentation tank culture, after filtration, purify, dry, pulverize, composite, canned this product obtained.
Embodiment two:
Of the present invention pulp furnish different from described in embodiment one is different, by weight percentage, and Ganoderma Peptide Polysaccharide 60%, Siberian solomonseal rhizome polysaccharide 30%, polysaccharide from urtica fissa 10%.
Embodiment three:
Different from described in embodiment one is that pulp furnish of the present invention is different, by weight percentage, and Ganoderma Peptide Polysaccharide 40%, Siberian solomonseal rhizome polysaccharide 10%, polysaccharide from urtica fissa 50%.
Claims (4)
1. Ganoderma lucidum Peptides Siberian solomonseal rhizome polysaccharide and a preparation technology thereof, it is characterized in that it is made up of Ganoderma Peptide Polysaccharide, sealwort peptide polysaccharide, polysaccharide from urtica fissa, its percentage by weight is: Ganoderma Peptide Polysaccharide 20-60%, Siberian solomonseal rhizome polysaccharide 10-50%, polysaccharide from urtica fissa 10-50%.
2. a kind of Ganoderma lucidum Peptides Siberian solomonseal rhizome polysaccharide according to claim 1 and preparation technology thereof, is characterized in that; The deep liquid fermentation process of fungi, comprise Ganoderma Peptide Polysaccharide, Siberian solomonseal rhizome polysaccharide, polysaccharide from urtica fissa, concrete technology flow process is as follows: bacterial classification → inclined-plane cultivate 20 ~ 30 days → Shaking culture, 1 ~ 6 day → fermentation tank culture, 1 ~ 6 day → filter mycelium and refine mycelium → purification polysaccharide → drying → pulverizing in nutrient solution → composite → filling → pack.
3. a kind of Ganoderma lucidum Peptides Siberian solomonseal rhizome polysaccharide according to claim 2 and preparation technology thereof, is characterized in that: cultivate humidity at-2 DEG C ~-4 DEG C, nutrient solution ρ h value at 5-7.8, grinding particle size 80 order---200 orders.
4. a kind of Ganoderma lucidum Peptides Siberian solomonseal rhizome polysaccharide according to claim 2 and preparation technology thereof, is characterized in that: peptidoglycan content can more than 80% according to weight ratio.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410723880.5A CN104522461A (en) | 2014-12-04 | 2014-12-04 | Glossy ganoderma peptide rhizoma polygonati polysaccharide and preparation technology thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410723880.5A CN104522461A (en) | 2014-12-04 | 2014-12-04 | Glossy ganoderma peptide rhizoma polygonati polysaccharide and preparation technology thereof |
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| Publication Number | Publication Date |
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| CN104522461A true CN104522461A (en) | 2015-04-22 |
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| CN201410723880.5A Pending CN104522461A (en) | 2014-12-04 | 2014-12-04 | Glossy ganoderma peptide rhizoma polygonati polysaccharide and preparation technology thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232587A (en) * | 2015-09-25 | 2016-01-13 | 南陵县襄荷产业协会 | Lucid ganoderma health-care capsule processing method |
| CN106834392A (en) * | 2017-02-16 | 2017-06-13 | 江苏中祥高科技实业有限公司 | A kind of method that Ganoderma lucidum Peptides are extracted in the ganoderma lucidum from liquid deep layer fermenting |
| CN111671764A (en) * | 2020-05-06 | 2020-09-18 | 广东华夏友美生物科技有限公司 | Application of ganoderic acid polysaccharide in preparation of skin histamine inhibitor |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010055274A (en) * | 1999-12-10 | 2001-07-04 | 김재수 | Health augmentation food for the anti fatigue |
| CN1429837A (en) * | 2001-12-29 | 2003-07-16 | 福州绿谷生物药业技术研究所 | Grass planted ganoderma polysaccharide peptide and its extraction method |
| CN1865289A (en) * | 2005-05-16 | 2006-11-22 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | Preparation and uses of polysaccharide from urtica fissa |
| CN1896095A (en) * | 2006-05-24 | 2007-01-17 | 中国食品发酵工业研究院 | Lucid ganoderma sugar peptide, its production and use |
| CN101580552A (en) * | 2009-06-24 | 2009-11-18 | 张海悦 | Preparation method of urtica angustifolia polysaccharide and application thereof |
| CN102757513A (en) * | 2012-07-25 | 2012-10-31 | 陕西理工学院 | Preparation technology of polygonatum polysaccharide peptide |
| CN104116755A (en) * | 2014-06-19 | 2014-10-29 | 无限极（中国）有限公司 | Ganoderma lucidum, wolfberry and rhizoma polygonati compound polysaccharide with tumor microenvironment regulation function as well as preparation method and application thereof |
-
2014
- 2014-12-04 CN CN201410723880.5A patent/CN104522461A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010055274A (en) * | 1999-12-10 | 2001-07-04 | 김재수 | Health augmentation food for the anti fatigue |
| CN1429837A (en) * | 2001-12-29 | 2003-07-16 | 福州绿谷生物药业技术研究所 | Grass planted ganoderma polysaccharide peptide and its extraction method |
| CN1865289A (en) * | 2005-05-16 | 2006-11-22 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | Preparation and uses of polysaccharide from urtica fissa |
| CN1896095A (en) * | 2006-05-24 | 2007-01-17 | 中国食品发酵工业研究院 | Lucid ganoderma sugar peptide, its production and use |
| CN101580552A (en) * | 2009-06-24 | 2009-11-18 | 张海悦 | Preparation method of urtica angustifolia polysaccharide and application thereof |
| CN102757513A (en) * | 2012-07-25 | 2012-10-31 | 陕西理工学院 | Preparation technology of polygonatum polysaccharide peptide |
| CN104116755A (en) * | 2014-06-19 | 2014-10-29 | 无限极（中国）有限公司 | Ganoderma lucidum, wolfberry and rhizoma polygonati compound polysaccharide with tumor microenvironment regulation function as well as preparation method and application thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232587A (en) * | 2015-09-25 | 2016-01-13 | 南陵县襄荷产业协会 | Lucid ganoderma health-care capsule processing method |
| CN106834392A (en) * | 2017-02-16 | 2017-06-13 | 江苏中祥高科技实业有限公司 | A kind of method that Ganoderma lucidum Peptides are extracted in the ganoderma lucidum from liquid deep layer fermenting |
| CN111671764A (en) * | 2020-05-06 | 2020-09-18 | 广东华夏友美生物科技有限公司 | Application of ganoderic acid polysaccharide in preparation of skin histamine inhibitor |
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| PB01 | Publication | ||
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| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Huang Yanhong Inventor before: Huang Yanhong Inventor before: Yang Fuguo Inventor before: Liu Fuling Inventor before: Guo Shiping |
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| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160121 Address after: 063000, building 401, room 402, Eastern Mansion, No. 152, Jianshe North Road, Tangshan City hi tech Zone, Hebei, Applicant after: Tangshan Yu Yu Biotechnology Co., Ltd. Address before: 063000 block 152, Eastern Mansion, Tangshan City hi tech Development Zone, Hebei, 401, C Applicant before: Huang Yanhong |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150422 |
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| RJ01 | Rejection of invention patent application after publication |