CN104491621A - 一种治疗糖尿病的中药组合物 - Google Patents

一种治疗糖尿病的中药组合物 Download PDF

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CN104491621A
CN104491621A CN201410756100.7A CN201410756100A CN104491621A CN 104491621 A CN104491621 A CN 104491621A CN 201410756100 A CN201410756100 A CN 201410756100A CN 104491621 A CN104491621 A CN 104491621A
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高田田
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Abstract

本发明公开了一种治疗糖尿病的中药组合物,属于中药技术领域,由下述原料制备而成:党参,人参,天花粉,赤芍,白术,五味子,丹皮,夏枯草,三棱,当归,丹皮,菟丝子,龙骨,党参,麦冬,泽泻,知母,石斛,黄芪,何首乌,地骨皮和甘草。本发明将上述药物组合后,其药效具有协同作用,具有活血通络、益气健脾、滋阴补肾、化痰逐瘀的功效。该种治疗糖尿病的中药组合物在治疗糖尿病方面具有见效快,疗程短、治疗方法简单、费用低、对身体无任何副作用、不会对患者的健康有任何不利影响等优点。

Description

一种治疗糖尿病的中药组合物
技术领域
本发明涉及一种治疗糖尿病的中药组合物,属于中药技术领域。
背景技术
糖尿病是一种以高血糖为特征的代谢性疾病。属于内分泌代谢系统疾病,可导致失明,肾功能衰竭,严重影响人类健康,故称之为人类隐形杀手。随着社会经济的发展和生活方式的改变,糖尿病的患病率正逐渐上升,目前估计全世界已有1.2亿糖尿病病人,我国约有1千多万,且发病率仍呈逐年上升趋势。糖尿病的临床表现以高血糖为主要标志,临床上出现烦渴、多尿、多饮、多食、疲乏、消瘦、尿糖等表现。
目前对于糖尿病尚无根治方法,治疗中医对于治疗糖尿病有一定的疗效,但这些西药普遍毒副作用大,久用会损害肝脏、肾脏及血细胞。由此可见,降糖西药是一把双刃剑,一方面控制血糖,另一方面也在毒害生命。中医药治疗糖尿病毒副作用小,但目前现有的中药制剂治疗糖尿病存在疗程长,疗效不明显等弊端。
发明内容
本发明的目的在于提供一种治疗糖尿病的中药组合物,全部选用天然中草药,治疗糖尿病有显著疗效。
本发明的技术方案是:一种治疗糖尿病的中药组合物,其特征是,由以下重量的中药制成:
党参5-15克,人参5-15克,天花粉5-15克,赤芍5-15克,白术5-15克,五味子5-15克,丹皮5-15克,夏枯草5-15克,三棱5-15克,当归10-20克,丹皮10-20克,菟丝子10-20克,龙骨10-20克,党参10-20克,麦冬10-20克,泽泻10-20克,知母10-20克,石斛10-20克,黄芪15-25克,何首乌15-25克,地骨皮15-25克,甘草3-8克。
优选的,由以下重量的中药制成:
党参10克,人参10克,天花粉10克,赤芍10克,白术10克,五味子10克,丹皮10克,夏枯草10克,三棱10克,当归15克,丹皮15克,菟丝子15克,龙骨15克,党参15克,麦冬15克,泽泻15克,知母15克,石斛15克,黄芪20克,何首乌20克,地骨皮20克,甘草6克。
配制及服用方法:
①根据上述的重量称取原料;
②将步骤①中称取的内服药物原料置于砂锅中,然后加水至没过原料2-5cm,浸泡10-20min后,加热至50℃,加盖保温20-50min;然后大火加热至沸腾,转小火煎煮30-90min,过滤,得滤液一,滤渣留于锅中,加水至没过滤渣,继续煎煮10-20min,过滤,得滤液二;
③将滤液一和滤液二合并,混合即可。
分别于早饭前半小时,晚饭后两小时服用。连服15天为一疗程。
各中药的药理作用:
党参:甘,平。入手、足太阴经气分。补中益气,生津,养血。用于中气不足的体虚倦怠,脾胃虚弱,气血两亏,治体倦无力,肺气亏虚。治食少,口渴,久泻,脱肛。及气血双亏的面色萎黄,头晕心悸等。
人参:味甘,微苦,性微温,归肺、脾经,有大补元气,补肺健脾,生津止渴之效。西医实验证明其对糖代谢有双向调节作用。
天花粉:生津,止渴,降火,润燥,排脓,消肿。治热病口喝,消渴,黄疸,肺燥咳血,痈肿。
赤芍:苦,微寒。归肝经。清热凉血,散瘀止痛。用于温毒发斑,吐血衄血,目赤肿痛,肝郁胁痛,经闭痛经,癥瘕腹痛,跌扑损伤,痈肿疮疡。
白术:苦甘,温。入脾、胃经。补脾,益胃,燥湿,和中,安胎。治脾胃气弱,不思饮食,倦怠少气,虚胀,泄泻,痰饮,水肿,黄疸,湿痹,小便不利,头晕,自汗,胎气不安。
五味子:酸,温。入肺、肾经,敛肺,滋肾,生津,收汗,涩精。治肺虚喘咳,口干作渴,自汗,盗汗,劳伤羸瘦,梦遗滑精,久泻久痢。
丹皮:清热,凉血,和血,消瘀。治热入血分,发斑,惊痫,吐、衄、便血,骨蒸劳热,经闭,癥瘕,痈疡,扑损。
夏枯草:苦辛,寒。入肝、胆经。清肝,散结。治瘰疬,瘿瘤,乳痈,乳癌,目珠夜痛,羞明流泪,头目眩晕,口眼歪斜,筋骨疼痛,肺结核,急性黄疸型传染性肝炎,血崩,带下。
三棱:苦辛,平。入肝。脾经。破血,行气,消积,止痛。治癥瘕积聚,气血凝滞,心腹疼痛,胁下胀疼,经闭,产后瘀血腹痛,跌打损伤。疮肿坚硬。
当归:甘辛,温。入心、肝、脾经。补血和血,调经止痛,润燥滑肠。治月经不调,经闭腹痛,癥瘕结聚,崩漏;血虚头痛,眩晕,痿痹;肠燥便难,赤痢后重;痈疽疮窃,跌扑损伤。
丹皮:清热,凉血,和血,消瘀。治热入血分,发斑,惊痫,吐、衄、便血,骨蒸劳热,经闭,癥瘕,痈疡,扑损。
菟丝子:补肝痛,益精髓,明目。治腰膝酸痛,消渴,目暗。
龙骨:镇惊安神,敛汗固精,止血涩肠,生肌敛疮。治惊痫癫狂,失眠多梦,自汗盗汗,遗精淋浊,吐衄便血,崩漏带下,泻痢脱肛。
党参:甘,平。入手、足太阴经气分。补中益气,生津,养血。用于中气不足的体虚倦怠,脾胃虚弱,气血两亏,治体倦无力,肺气亏虚。治食少,口渴,久泻,脱肛。及气血双亏的面色萎黄,头晕心悸等。
麦冬:味甘、微苦,性寒,归肺、胃、心经,有养阴润肺,益胃生津,清心除烦之功。西医实验证明给予家兔服用麦冬水及醇提取物,有降低血糖作用,并能促进胰岛细胞的修复。
泽泻:甘,寒。入肾、膀胱经。利水,渗湿,泄热。治小便不利,水肿胀满,呕吐,泻痢,痰饮,脚气,淋病,尿血。
知母:苦,寒。入肺、胃、肾经。滋阴降火,润燥滑肠。治烦热消渴,骨蒸劳热,肺热咳嗽,大便燥结,小便不利。
石斛:甘淡微咸,寒。入胃、肺,肾经。生津益胃,清热养阴。治热病伤津,口干烦渴,病后虚热,阴伤目暗。
黄芪:性温,味甘。补气升阳,益卫固表、托毒生肌、利水退肿。主治脾胃虚弱,食少倦怠,气虚血脱,表虚自汗、盗汗。
何首乌:苦甘涩,微温。入肝、肾经。补肝,益肾,养血,祛风。治肝肾阴亏,发须早白,血虚头晕,腰膝软弱,筋骨酸痛,遗精,崩带,久疟,久痢,慢性肝炎,痈肿,瘰疬,肠风,痔疾。
地骨皮:清热,凉血,治虚劳潮热盗汗,肺热咳喘,痈肿恶疮。
甘草:甘,平。归心、肺、脾、胃经。补脾益气,滋咳润肺,缓急解毒,调和百药。主治咽喉肿痛,痛疽疮疡,胃肠道溃疡以及解药毒、食物中毒等。
本发明的有益效果是:本发明将上述药物组合后,其药效具有协同作用,具有活血通络、益气健脾、滋阴补肾、化痰逐瘀的功效。该种治疗糖尿病的中药组合物在治疗糖尿病方面具有见效快,疗程短、治疗方法简单、费用低、对身体无任何副作用、不会对患者的健康有任何不利影响等优点。
以下结合临床资料及典型病例对本发明的有益效果进一步说明。
一、临床观察
1、临床资料:选糖尿病患者共134例,年龄为33-75岁,平均58.5岁。其中男66例,女69例,病程2个月-21年。
2、诊断标准:
(1)有糖尿病症状(多尿、多饮及不能解释的体重下降),并且随机(餐后任何时间)血浆葡萄糖≥11.1mmol/L(200mg/dl);
(2)或者空腹(禁食至少8小时)血浆葡萄糖≥7.0mmol/L(126mg/dl);
(3)或者OGTT 2小时血浆葡萄糖≥11.1mmol/L(200mg/dl)
空腹血糖损伤(IFG):是指空腹血浆葡萄糖≥6.1mmol/L(110mg/dl),但<7.0mmol/L(126mg/dl)。
糖耐量损伤(IGT):是指OGTT 2小时血浆葡萄糖≥7.8mmol/L(140mg/dl),但<11.1mmol/L(200mg/dl)。
3、治疗方法:服用本发明药物,水煎煮,分两次早晚服用。15天为1个疗程。
4、疗效评定标准:
显效:临床体征以及症状改善明显,餐后2h以及空腹血糖正常;
有效:临床体征以及症状改善出现好转,餐后2h以及空腹血糖水平下降幅度大于25%;
无效:临床体征以及症状无好转迹象,餐后2h以及空腹血糖水平变化不明显。
5、治疗结果:显效118例,为88.1%;有效13例,为9.7%;无效3例,为2.2%;总有效率为97.8%。未发现不良反应和并发症。
综上所述,本发明用于治疗糖尿病的中药组合物,经临床试验,表明其在糖尿病的治疗以及病情控制方面,具有较好的治疗效果,且无明显毒副作用。
二、典型病例
病例1:宋某某,男,56岁,患糖尿病多年,经多家医院治疗,吃了不少药物,总是时好时坏,感到四肢无力、头晕眼花、口渴、夜尿多、长期失眠。自从服用本方剂3个疗程后,经医院检查血、尿糖均恢复到正常值,症状明显减轻,睡眠正常。经巩固治疗1疗程后,已完全康复,现已停药1年,随访至今尚未复发和反弹。
病例2:胡某某,女,67岁。患者近来出现出虚汗、头痛、头晕、视物模糊等症状,在当地医院检查诊断为糖尿病。服用本发明药物治疗1个疗程后,出虚汗、头痛、头晕症状好转,视力恢复,眼睛无不适症状,继续服药治疗2个疗程,出汗、口渴明显好转,身体其它不适症状全部消失。随访至今,无其它不适感觉。
病例3:王某某,男,52岁。患者最近半年来体重下降,饭量增大,浑身无力,腰酸背痛。去医院检查血糖13.5mmol/L尿糖(+++),诊断为Ⅱ型糖尿病。服用西药治疗一段时间后,症状未见明显改善,后来他听从了中医的建议改用中药治疗,在服用本发明药物2个疗程后,糖尿病的并发症现象全部消失,检查血糖、尿糖正常,跟踪回访,一年多以来未复发。
具体实施方式
实施例1:一种治疗糖尿病的中药组合物,由以下重量的中药制成:
党参10克,人参10克,天花粉10克,赤芍10克,白术10克,五味子10克,丹皮10克,夏枯草10克,三棱10克,当归15克,丹皮15克,菟丝子15克,龙骨15克,党参15克,麦冬15克,泽泻15克,知母15克,石斛15克,黄芪20克,何首乌20克,地骨皮20克,甘草6克。
配制及服用方法:
①根据上述的重量称取原料;
②将步骤①中称取的内服药物原料置于砂锅中,然后加水至没过原料2-5cm,浸泡10-20min后,加热至50℃,加盖保温20-50min;然后大火加热至沸腾,转小火煎煮30-90min,过滤,得滤液一,滤渣留于锅中,加水至没过滤渣,继续煎煮10-20min,过滤,得滤液二;
③将滤液一和滤液二合并,混合即可。
分别于早饭前半小时,晚饭后两小时服用。连服15天为一疗程。
实施例2:一种治疗糖尿病的中药组合物,由以下重量的中药制成:
党参10克,人参10克,天花粉10克,赤芍10克,白术10克,五味子10克,丹皮15克,夏枯草15克,三棱15克,当归15克,丹皮15克,菟丝子15克,龙骨15克,党参15克,麦冬15克,泽泻15克,知母15克,石斛15克,黄芪20克,何首乌20克,地骨皮20克,甘草6克。
配制及服用方法:同例1。
实施例3:一种治疗糖尿病的中药组合物,由以下重量的中药制成:
党参10克,人参10克,天花粉10克,赤芍10克,白术10克,五味子10克,丹皮10克,夏枯草10克,三棱10克,当归15克,丹皮15克,菟丝子15克,龙骨15克,党参15克,麦冬20克,泽泻20克,知母20克,石斛20克,黄芪20克,何首乌20克,地骨皮20克,甘草6克。
配制及服用方法:同例1。
实施例4:一种治疗糖尿病的中药组合物,由以下重量的中药制成:
党参10克,人参10克,天花粉10克,赤芍12克,白术12克,五味子12克,丹皮12克,夏枯草12克,三棱12克,当归12克,丹皮12克,菟丝子15克,龙骨15克,党参15克,麦冬15克,泽泻15克,知母15克,石斛15克,黄芪20克,何首乌20克,地骨皮20克,甘草3克。
配制及服用方法:同例1。
实施例5:一种治疗糖尿病的中药组合物,由以下重量的中药制成:
党参10克,人参10克,天花粉10克,赤芍10克,白术10克,五味子10克,丹皮10克,夏枯草10克,三棱10克,当归10克,丹皮10克,菟丝子10克,龙骨10克,党参15克,麦冬15克,泽泻15克,知母15克,石斛15克,黄芪25克,何首乌25克,地骨皮25克,甘草3克。
配制及服用方法:同例1。

Claims (2)

1.一种治疗糖尿病的中药组合物,其特征是,由以下重量的中药制成:
党参5-15克,人参5-15克,天花粉5-15克,赤芍5-15克,白术5-15克,五味子5-15克,丹皮5-15克,夏枯草5-15克,三棱5-15克,当归10-20克,丹皮10-20克,菟丝子10-20克,龙骨10-20克,党参10-20克,麦冬10-20克,泽泻10-20克,知母10-20克,石斛10-20克,黄芪15-25克,何首乌15-25克,地骨皮15-25克,甘草3-8克。
2.根据权利要求1所述的治疗糖尿病的中药组合物,其特征是,由以下重量的中药制成:
党参10克,人参10克,天花粉10克,赤芍10克,白术10克,五味子10克,丹皮10克,夏枯草10克,三棱10克,当归15克,丹皮15克,菟丝子15克,龙骨15克,党参15克,麦冬15克,泽泻15克,知母15克,石斛15克,黄芪20克,何首乌20克,地骨皮20克,甘草6克。
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