CN104491533A - Traditional Chinese medicine for preventing and treating duck virus hepatitis - Google Patents
Traditional Chinese medicine for preventing and treating duck virus hepatitis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for preventing and treating duck virus hepatitis. The problems that the conventional product is high in price and short of source of goods, a stress risk generated to ill young ducks exists in the injection process and the treatment effect is bad can be effectively solved. According to the technical scheme for solving the problems, the traditional Chinese medicine is prepared from the following raw material medicines in parts by weight: 13-15 parts of radix gentianae, 10-12 parts of radix sophorae flavescentis, 8-10 parts of coptis chinensis, 7-9 parts of rhizome of rehmannia, 6-8 parts of radix bupleuri, 4-6 parts of cortex lycii radicis, 4-6 parts of astragalus, 4-6 parts of panax pseudoginseng, 4-6 parts of lalang grass rhizome, 4-6 parts of selfheal, 4-6 parts of chrysanthemum and 4-6 parts of liquorice. The preparation method comprises the following steps: uniformly mixing the raw material medicines, grinding, screening by using an 80-100mesh sieve, and split-charging, thereby obtaining the traditional Chinese medicine. The traditional Chinese medicine disclosed by the invention is strict in formula, exact in curative effect, simple and convenient to use and easy to operate, does not have antibiont residues, can be used for effectively preventing and treating the duck virus hepatitis, is good in service effect and is an innovation of the medicine for treating the duck virus hepatitis.
Description
Technical field
The present invention relates to field of medicaments, particularly a kind of Chinese medicine preventing and treating Duck Hepatitis Virus.
Background technology
Duck viral hepatitis is a kind of Acute exposure sexually transmitted disease being caused duckling by DHV.Primary disease has the feature of high contact, high lethal, and there is generation in area more in the southwest of China, North China, Central China, East China, south China etc., and the four seasons all can be broken out.Primary disease is infected duck only, duckling susceptible disease, and adult duck does not fall ill.In the season of duckling hatching, multiple popular, duckling sickness rate can reach 100%, and in 3 week age, duckling case fatality rate can reach 50 ~ 95%.Their early stage visible duckling spirit is tired, and appetite is absolutely useless, and eye semi-closure is comatose state, ash discharge white or green watery stools.There is nervous symptoms in duckling subsequently, and health is crooked, the spastic paddling of two lower limbs, opisthotonus, dead after a few hours.
Duck viral hepatitis is caused by DHV, is DHV (DHV) I, II, III type respectively, and modal is DHV I type, belongs to enterovirus.Size 20 ~ the 40nm of virus, the resistance of environment is very strong to external world, and at least can survive 10 weeks in the indoor virus of brooding polluted, the virus in dark and damp place feces can be survived 37 days.By feces, crib, drinking-water cause duck only between propagation, easily cause pandemic in breeding-ground compact district, cause huge economic loss.
Treatment is greater than at present for primary disease prevention, stop to buy duckling from morbidity duck field or hatching room, guarantee feeding environment sanitary cleaning, certain guarantee duck immunity, its maternal antibody produced can maintain about 2 weeks time in duckling body, susceptible critical days can be spent, the active immunity of duck hepatitis vaccine can be carried out in epidemic season at duckling 10 ~ 14 age in days.If cannot determine, whether duck is immune, should duckling in 1 age in days active immunity vaccine.Mostly treatment aspect at present for primary disease is to adopt high immunity yolk antibody, and this product exists the feature that price is high, the source of goods is in short supply, and domestic only have several biological product enterprises to produce, and also exist in injection process to sick young produce stress risk.In addition, commercially available also have herbal medicine to treat this disease, but due to formula and using method not rigorous, therapeutic effect is also barely satisfactory.Therefore, the improvement for the treatment of on the medicine of duck viral hepatitis is the problem needing solution at present badly.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the object of the present invention is just to provide a kind of Chinese medicine preventing and treating Duck Hepatitis Virus, effectively can solve that existing product price is high, the source of goods is in short supply, exist in injection process to sick young produce stress risk, the problem of therapeutic effect difference.
The technical scheme that the present invention solves is, this Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 13-15 part, Radix Sophorae Flavescentis 10-12 part, Rhizoma Coptidis 8-10 part, Radix Rehmanniae 7-9 part, Radix Bupleuri 6-8 part, Cortex Lycii 4-6 part, Radix Astragali 4-6 part, Radix Notoginseng 4-6 part, Rhizoma Imperatae 4-6 part, Spica Prunellae 4-6 part, Flos Chrysanthemi 4-6 part and Radix Glycyrrhizae 4-6 part, above-mentioned raw materials medicine is mixed, pulverizes, cross 80-100 mesh sieve, subpackage and get final product.
Formula of the present invention is rigorous, curative effect remains really, without antibiont, and it is simple, convenient, easy to operate to use, can effective prevention and therapy Duck Hepatitis Virus, and result of use is good, is to treat the innovation on the medicine of duck viral hepatitis.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
This Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 13 parts, Radix Sophorae Flavescentis 12 parts, Rhizoma Coptidis 8 parts, 9 parts, the Radix Rehmanniae, Radix Bupleuri 6 parts, Cortex Lycii 6 parts, the Radix Astragali 4 parts, Radix Notoginseng 6 parts, Rhizoma Imperatae 4 parts, Spica Prunellae 6 parts, Flos Chrysanthemi 4 parts and 6 parts, Radix Glycyrrhizae, above-mentioned raw materials medicine is mixed, pulverizes, cross 80 mesh sieves, subpackage and get final product.
Embodiment 2
This Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 14 parts, Radix Sophorae Flavescentis 11 parts, Rhizoma Coptidis 9 parts, 8 parts, the Radix Rehmanniae, Radix Bupleuri 7 parts, Cortex Lycii 5 parts, the Radix Astragali 5 parts, Radix Notoginseng 5 parts, Rhizoma Imperatae 5 parts, Spica Prunellae 5 parts, Flos Chrysanthemi 5 parts and 5 parts, Radix Glycyrrhizae, above-mentioned raw materials medicine is mixed, pulverizes, cross 90 mesh sieves, subpackage and get final product.
Embodiment 3
This Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Coptidis 10 parts, 7 parts, the Radix Rehmanniae, Radix Bupleuri 8 parts, Cortex Lycii 4 parts, the Radix Astragali 6 parts, Radix Notoginseng 4 parts, Rhizoma Imperatae 6 parts, Spica Prunellae 4 parts, Flos Chrysanthemi 6 parts and 4 parts, Radix Glycyrrhizae, above-mentioned raw materials medicine is mixed, pulverizes, cross 100 mesh sieves, subpackage and get final product.
Chinese veterinarian thinks: duckling honey stomach but the spleen tending to insufficiency usually, and digestive function is poor, the liver being liable to excess, be subject to the infection of DHV, heat-transformation in the ill rear easy biography of duckling, Chang Yindong liver-wind, other internal organs also often cause mixed infection, harm liver, intestinal, spleen, each internal organs of stomach.The ill virus hepatitis of duckling, card belongs to epidemic febrile disease scope, for experience epidemic disease heresy caused by.According to differentiation of disease according to pathological changes of the viscera and their analysis, duck experiences virus attack liver, cause deficiency of heart-QI, blood circulation can not be presided over and to circulate each warp, YIN nourishing whole body, alluvial heat-dissipating, heat in blood is then withered, as now of a specified duration, then causes death, so its Therapeutic Principle should be heat-clearing and toxic substances removing, antiinflammatory protects the liver, soothing the liver spasmolytic, replenishing QI to invigorate the spleen, blood circulation promoting and blood stasis dispelling are main.
According to above-mentioned theory and principle, the invention provides a kind of like this Chinese prescription preventing and treating Duck Hepatitis Virus, comprising: Radix Gentianae, Radix Sophorae Flavescentis, Rhizoma Coptidis, the Radix Rehmanniae, Radix Bupleuri, Cortex Lycii, the Radix Astragali, Radix Notoginseng, Rhizoma Imperatae, Spica Prunellae, Flos Chrysanthemi, Radix Glycyrrhizae.
Radix Gentianae is the dry root welding technology of gentianaceae plant Radix Gentianae, and bitter in the mouth is trembled with fear, and enters liver, gallbladder, urinary bladder channel, has heat clearing and damp drying, let out excess-fire of the liver, the effect of clear dampness-heat of the liver, can treat Liver Channel intenseness of heat, extreme heat causing wind syndrome, tic spasm with Rhizoma Coptidis compatibility.
Radix Sophorae Flavescentis is the dry root of leguminous plant Radix Sophorae Flavescentis, and bitter in the mouth is trembled with fear, and enters urinary bladder channel, has effect of heat clearing and damp drying, treats dampness-heat in the liver and gallbladder with Radix Gentianae with using.Its effective ingredient matrine is inhibited to multiple pathogenic microorganisms, and is improved the function of immunity of organisms.
Rhizoma Coptidis is the dry rhizome of Mao Liangke plant Rhizoma Coptidis, bitter in the mouth is trembled with fear, enter the heart, liver, stomach, large intestine channel, it is the key medicine of heat clearing and damp drying, especially the most suitable with the disease of gastrointestinal stagnation of damp-heat, to escherichia coli, staphylococcus, hepatitis virus and Mycophyta, there is good inhibitory action containing multiple alkaloid, the leukocytic phagocytic function of body can be improved simultaneously.
The Radix Rehmanniae is the dried root of scrophulariaceae rehmannia glutinosa plant, sweet in the mouth, hardship, cold, entering the heart, liver, kidney channel, has effect of clearing away heat and cooling blood and yin nourishing, with Cortex Lycii with treating yin asthenia generating intrinsic heat, having cooling blood for hemostasis, effect of promoting the production of body fluid to quench thirst simultaneously.
Radix Bupleuri is the dry root of umbelliferae bupleurum, bitter in the mouth, is slightly cold, and entering liver, gallbladder, pericardium, tri-jiao channel, have effect of reducing fever by reconciliation, depressed liver-energy dispersing and QI regulating, elevate a turnable ladder yang-energy, is the key medicine for the treatment of SHAO YANG disease by mediation warp.There is antipyretic, analgesia, function of gallbladder promoting, anti-liver injury effect simultaneously inhibited to antibacterial, virus.
Cortex Lycii is the dry root bark of matrimony vine of solanaceae plant, sweet in the mouth, cold, enters lung, kidney, Liver Channel, has clearing away heat and cooling blood, effect of reducing the asthenic fever, with Rhizoma Imperatae with by the various hemorrhages can treated caused by bleeding due to blood-heat.
The Radix Astragali is the dry root of leguminous plant Radix Astragali, and sweet in the mouth, tepor enter spleen, lung meridian, has effect of tonifying Qi and lifting yang, promoting pus discharge and tissue regeneration strengthening, replenishing QI to invigorate the spleen, diuretic detumescent.To the heart of exhaustion, there is cardiotonic, inhibited to streptococcus, staphylococcus.
Radix Notoginseng is the dry root of panax araliaceae plant, sweet in the mouth, micro-hardship, temperature, enters liver, stomach warp, has dissipating blood stasis hemostasis, effect that the stasis of blood is not stayed in reducing swelling and alleviating pain, hemostasis, can shorten blood clotting time, make platelet increase and stop blooding.
Spica Prunellae is the dry fruit ear of labiate Spica Prunellae, and taste bitter, acrid, cold, enter liver and gall warp, and normal and Flos Chrysanthemi is same with letting out liver-fire clearly, Disperse hepatic depression.
Rhizoma Imperatae is the dry rhizome of grass Herba Imperatae, sweet in the mouth, cold, enters lung, stomach warp, has the effect of hemostasis and clearing away heat and cooling blood.
Flos Chrysanthemi is the dry capitulum of feverfew chrysanthemum, sweet in the mouth, hardship, is slightly cold, and enters lung, Liver Channel, has effect of wind and heat dispersing, liver heat removing item and removing toxic substances, has the effect of antibacterial, antiinflammatory, antipyretic and blood pressure lowering.
Radix Glycyrrhizae is the dry rhizome of glycyrrhizic legume, sweet in the mouth, flat, enters 12 warps, has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, the mitigation property of medicine.
Medicament composing prescription of the present invention is the classical prescription good recipe using for reference motherland's traditional medicine, and design in conjunction with the physiological characteristics of duckling and the clinical symptoms of viral hepatitis, this disease mainly infects duckling in 0 ~ 3 week age, occur lethargy, lethargy during their early stage, then occur nervous symptoms, movement disorder, health swings to side, bipod generation spasm, dead front is fallen backward, in opisthotonus attitude, dead after a few hours.Cut open the visible liver enlargement of inspection, age in days is dirty compared with poult duck liver in khaki, above visible obviously petechia and ecchymosis, the larger duckling liver of age in days is soil Red, also shows petechia or ecchymosis.The effective compatibility of Chinese prescription of the present invention, synergism, can be effective to prevention and therapy duck viral hepatitis.Related tests data is as follows:
Chinese medicine of the present invention can adopt following two kinds of methods when using:
The first: directly spice, Chinese medicine: feedstuff (1:100) spice, eats for morbidity duckling, connects and feed 7 days.
The second: boiling water braises, Chinese medicine: water (1:100) adds boiling water, sealing braises 20 ~ 30 minutes, treat that effective ingredient is separated out, freely drink water for morbidity duckling when placing room temperature, connect and feed 7 days, also can add a small amount of electrolyte and vitamin C before drinking-water, supplement duckling ability, promote the performance of drug effect.
experiment one:
For examination duck field: Puyang Qingfeng County, Henan Province watt home town individual duckery.
For examination duck group: 10 ages in days, Cherry Village Ducks duck is young.
Duck group quantity: 900, with group with house, feeding and management condition is identical, because of kind of a duck immuning failure, enter young front sterilization not thorough, feeding and management management condition differences etc. are multifactor and bring out primary disease, morbidity duckling are divided at random 3 groups, are followed successively by Chinese medicine test group 1, Chinese medicine test group 2, high-immunity yolk group.
Therapeutic scheme:
Chinese medicine test group 1:300 only, uses Chinese medicine spice of the present invention to treat.
Chinese medicine test group 2:300 only, uses Chinese medicine of the present invention to drink water and treats.
High-immunity yolk group: 300, uses commercially available duck viral hepatitis high-immunity yolk urgent immunity injection for curing.
(1) Chinese medicine test group 1 therapeutic progresses is as follows:
Take 300g this product (1g/ only), spice 30kg, mixes thoroughly, appoints duck group free choice feeding, continuous use 7 days;
(2) Chinese medicine test group 2 therapeutic progresses is as follows:
Take 300g this product (1g/ only) to add 30L boiling water and braise 20 ~ 30 minutes, centre will notice that the heat insulation effect of container is good, and after effective ingredient is separated out, uncap places room temperature, freely drink water for morbidity duckling, even hello 7 days;
(3) high-immunity yolk group:
Use commercially available duck viral hepatitis high-immunity yolk urgent immunity injection for curing, 0.5ml/ only, once a day, is used in conjunction 7 days;
Experimental result:
| Group | Morbidity duckling number (only) | Death toll (only) | Cure number (only) | Mortality rate % | Cure rate % |
| Chinese medicine test group 1 | 300 | 25 | 275 | 8.3 | 91.7 |
| Chinese medicine test group 2 | 300 | 15 | 285 | 5.0 | 95.0 |
| High-immunity yolk group | 300 | 32 | 268 | 10.6 | 89.4 |
Result shows: Chinese medicine test group 1,2 of the present invention reduces by 2.3 and 5.6 percentage points than the mortality rate of high-immunity yolk group respectively, and Chinese drug-treated group successful of the present invention is better than high-immunity yolk group.
experiment two:
For examination duck field: individual duckery of Liu Ta township, Puyang Qingfeng County, Henan Province.
For examination duck group: 15 ages in days, Beijing meat-type duck duck is young.
Duck group quantity: 1200, plant before duck is laid eggs and do not carry out immunity according to schedule, newborn duckling, when 15 ages in days turn group, is broken out primary disease suddenly, and presents the popularity fashion trend of duck group.Frank for appearance duckling is merged and is divided into 3 groups, be followed successively by this programme Chinese drug-treated group, commercially available Chinese drug-treated group, high-immunity yolk group.
This programme Chinese drug-treated group: 400, uses Chinese medicine of the present invention to drink water and treats.
Commercially available Chinese drug-treated group: 400, uses commercially available treatment duck viral hepatitis Chinese medicine " duck liver health " drinking-water to treat.
High-immunity yolk group: 400, uses commercially available duck viral hepatitis high-immunity yolk urgent immunity injection for curing.
(1) Chinese drug-treated group therapeutic progresses of the present invention is as follows:
Take 400g this product (1g/ only) to add 40L boiling water and braise, 20 ~ 30 minutes, centre will notice that the heat insulation effect of container is good, and after effective ingredient is separated out, uncap places room temperature, freely drink water for morbidity duckling, even hello 7 days;
(2) commercially available Chinese drug-treated group therapeutic progresses is as follows:
Take 400g duck liver health (1g/ only), add 40L boiling water and braise, mix thoroughly, freely drink water for morbidity duckling, connect and feed 7 days;
(3) high-immunity yolk group:
Use commercially available duck viral hepatitis high-immunity yolk urgent immunity injection for curing, 0.5ml/ only, once a day, is used in conjunction 7 days;
Experimental result:
| Group | Morbidity duckling number (only) | Death toll (only) | Cure number (only) | Mortality rate % | Cure rate % |
| Chinese drug-treated group of the present invention | 400 | 21 | 379 | 5.25 | 94.75 |
| Commercially available Chinese drug-treated group | 400 | 39 | 361 | 9.8 | 90.2 |
| High-immunity yolk group | 400 | 44 | 356 | 11.0 | 89.0 |
Result shows: Chinese drug-treated group of the present invention reduces by 4.55 and 5.75 percentage points than the mortality rate of commercially available Chinese drug-treated group and high-immunity yolk group respectively, illustrates that Chinese medicine successful of the present invention is better than commercially available Chinese drug-treated group and high-immunity yolk group.
The present invention many crowdes repeatedly, test of many times, all achieve good Advantageous Effects, shows that Chinese Herbs of the present invention is reliable and stable, has actual using value.
Conclusion:
Formula of the present invention is rigorous, curative effect remains really, without antibiont, and it is simple, convenient, easy to operate to use, can effective prevention and therapy Duck Hepatitis Virus, is prevent and treat the innovation on Duck Hepatitis Virus medicine, has good using value.
Claims (4)
1. prevent and treat the Chinese medicine of Duck Hepatitis Virus for one kind, it is characterized in that, this Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 13-15 part, Radix Sophorae Flavescentis 10-12 part, Rhizoma Coptidis 8-10 part, Radix Rehmanniae 7-9 part, Radix Bupleuri 6-8 part, Cortex Lycii 4-6 part, Radix Astragali 4-6 part, Radix Notoginseng 4-6 part, Rhizoma Imperatae 4-6 part, Spica Prunellae 4-6 part, Flos Chrysanthemi 4-6 part and Radix Glycyrrhizae 4-6 part, above-mentioned raw materials medicine is mixed, pulverizes, cross 80-100 mesh sieve, subpackage and get final product.
2. the Chinese medicine of control Duck Hepatitis Virus according to claim 1, it is characterized in that, this Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 13 parts, Radix Sophorae Flavescentis 12 parts, Rhizoma Coptidis 8 parts, 9 parts, the Radix Rehmanniae, Radix Bupleuri 6 parts, Cortex Lycii 6 parts, the Radix Astragali 4 parts, Radix Notoginseng 6 parts, Rhizoma Imperatae 4 parts, Spica Prunellae 6 parts, Flos Chrysanthemi 4 parts and 6 parts, Radix Glycyrrhizae, above-mentioned raw materials medicine is mixed, pulverizes, cross 80 mesh sieves, subpackage and get final product.
3. the Chinese medicine of control Duck Hepatitis Virus according to claim 1, it is characterized in that, this Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 14 parts, Radix Sophorae Flavescentis 11 parts, Rhizoma Coptidis 9 parts, 8 parts, the Radix Rehmanniae, Radix Bupleuri 7 parts, Cortex Lycii 5 parts, the Radix Astragali 5 parts, Radix Notoginseng 5 parts, Rhizoma Imperatae 5 parts, Spica Prunellae 5 parts, Flos Chrysanthemi 5 parts and 5 parts, Radix Glycyrrhizae, above-mentioned raw materials medicine is mixed, pulverizes, cross 90 mesh sieves, subpackage and get final product.
4. the Chinese medicine of control Duck Hepatitis Virus according to claim 1, it is characterized in that, this Chinese medicine is made up of the material medicine of following weight parts: Radix Gentianae 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Coptidis 10 parts, 7 parts, the Radix Rehmanniae, Radix Bupleuri 8 parts, Cortex Lycii 4 parts, the Radix Astragali 6 parts, Radix Notoginseng 4 parts, Rhizoma Imperatae 6 parts, Spica Prunellae 4 parts, Flos Chrysanthemi 6 parts and 4 parts, Radix Glycyrrhizae, above-mentioned raw materials medicine is mixed, pulverizes, cross 100 mesh sieves, subpackage and get final product.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107981089A (en) * | 2017-12-14 | 2018-05-04 | 安徽金冠农牧科技有限公司 | A kind of feed for preventing Duck Hepatitis Virus and preparation method thereof |
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| CN107981089A (en) * | 2017-12-14 | 2018-05-04 | 安徽金冠农牧科技有限公司 | A kind of feed for preventing Duck Hepatitis Virus and preparation method thereof |
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