CN104491314A - 一种治疗不孕不育的中药制剂及其制备方法 - Google Patents

一种治疗不孕不育的中药制剂及其制备方法 Download PDF

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CN104491314A
CN104491314A CN201410842773.4A CN201410842773A CN104491314A CN 104491314 A CN104491314 A CN 104491314A CN 201410842773 A CN201410842773 A CN 201410842773A CN 104491314 A CN104491314 A CN 104491314A
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赵红霞
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Abstract

本发明是一种治疗不孕不育的中药制剂及其制备方法——“促孕气血通关散”，由下列中药材制成，酒当归，黄芪，枸杞，淮山药，酒白芍，炒桑寄生，菟丝子，香附子，甘草，黑荆芥穗，制穿山甲，大熟地，五味子重量配比如下：酒当归500克，黄芪1000克，枸杞500克，淮山药500克，酒白芍500克，炒桑寄生300克，菟丝子600克，香附子200克，甘草100克，黑荆芥穗100克，制穿山甲200克，大熟地200克，五味子300克(此为5公斤药配比)药粉采用13味药(按精确重量配比)烘干、打磨成粉、经高温灭菌，防霉防腐等措施制成。本发明公开的中药具有调理肝肾行气血和冲任健脾益气达成促孕等功效，经60余载临床效验过程，其疗效优于目前市场治疗不孕不育的中药的产品，具有简、便、廉、疗效强等优点，比传统同类产品效果佳。

Description

一种治疗不孕不育的中药制剂及其制备方法
技术领域
本发明涉及一种治疗不孕不育的中药制剂及其制备方法，属于中药领域。
技术背景
女性不孕的主要原因可归纳为4类：①排卵功能障碍，表现为月经周期中无排卵，或虽然有排卵，但排卵后黄体功能不健全。②生殖器官发育异常或后天性生殖器官病变，阻碍从外阴至输卵管的生殖通道通畅和功能，妨碍精子与卵子相遇，导致不孕。③免疫学因素：系指女性生殖道或血清中存在有抗精子抗体，引起精子互相凝集，丧失活力或死亡，导致不孕或不育。此外，部分不孕妇女的血清中存在有对自身卵子透明带抗体样物质，可阻碍精子穿透卵子精子，亦可引起不孕。④性生活失调、性知识缺乏、全身系统性疾病及不明原因等引起的不孕约占不孕症病因的1/3左右。男性不孕的主要原因可归纳为5类：①性功能障碍包括阳痿、早泄、遗精、不射精等，不射精症占男性不育原因的32.4％。②精液质量异常，包括少精症、无精症、死精症、弱精症、多精症、精量过少及精液不液化等。少精症占男性不育原因的15.4％。③精索静脉曲张引起的男性不育占12％。④免疫学因素：指男子血清或精浆中存在有抗精子抗体，产生自身抗精子免疫反应，导致免疫性不育。⑤生殖道感染、先天性异常、全身性疾病及不明原因引起的不育。
发明内容
本发明的目的就是提供一种通过调理肝肾行气血和冲任健脾益气达成促孕治疗不孕不育的中药制剂及其制备方法(促孕气血通关散)。
本发明所述的中药制剂及其制备方法，它是由：酒当归，黄芪，枸杞，淮山药，酒白芍，炒桑寄生，菟丝子，香附子，甘草，黑荆芥穗，制穿山甲，大熟地，五味子等中药按如下方案制成，本发明药物各组份用量是：酒当归300g-500g，黄芪500g-1000g，枸杞300g-500g，淮山药300g-500g，酒白芍300g-500g，炒桑寄生150g-300g，菟丝子300g-600g，香附子100g-200g，甘草50g-100g，黑荆芥穗50g-100克，制穿山甲100g-200克，大熟地100g-200g，五味子100g-300g.(此为五公斤药的配比)。
制作工艺：当归.白芍分别用酒洗后炒制成微黄色，桑寄生.香附子分别炒至黄色，荆芥穗炒黑存性，穿山甲用沙土炒至黄色，大熟地慢火制干然后将十三位药粉碎过筛成细面。
具体实施方式
本发明所述的促孕气血通关散，它是由：酒当归，黄芪，枸杞，淮山药，酒白芍，炒桑寄生，菟丝子，香附子，甘草，黑荆芥穗，制穿山甲，大熟地，五味子按如下方案制成：
1.本发明药物各组份用量优选为：
酒当归500克，黄芪1000克，枸杞500克，淮山药500克，酒白芍500克，炒桑寄生300克，菟丝子600克，香附子200克，甘草100克，黑荆芥穗100克，制穿山甲200克，大熟地200克，五味子300克(此为制5公斤药的配比)。
2.用药的方法：
具有使用简便，价兼、见效快、疗效高，无药物依赖性，内服未见副作用。用法用量：于月经干净后，每日早，晚空腹服用各12克，10-15天为一疗程。
3.选择病例的标准：
男女不孕不育，如排卵功能障碍，生殖器官发育异常或后天性生殖器官病变，免疫学因素，性生活失调，性知识缺乏，男性性功能障碍，精液质量异常，精索静脉曲张，生殖道感染，先天性异常。
4.诊断标准：
排卵功能障碍，生殖器官发育异常或后天性生殖器官病变，免疫学因素，性生活失调，性知识缺乏，男性性功能障碍，精液质量异常，精索静脉曲张，生殖道感染，先天性异常。采用调理肝肾 行气血 和冲任 健脾益气 达成促孕治疗不孕不育的中药制剂及其制备方法(促孕气血通关散)。
5：治疗方案：
调气血，健脾益气，补肝益肾，和冲任。
6.疗效评定标准：
治愈：根据病情观察，一般1-5疗程可治愈。
有效：有的经过3-8个疗程后，病情立即减轻，慢慢治愈。
7.统计学处理：
根据上述3选择病例的治疗标准对患有不孕不育的1083人采用本发明制成的治疗不孕不育的中药制剂及其制备方法-促孕气血通关散，其中男378人，女705人，年龄最大者40岁，最小者22岁，平均28岁；病程最长者5年，最短者1年，5个疗程统计如下：治愈980人，有效95人，无效8人，总有效率99.38％，在用药期间没发现有任何毒副作用，安全可靠。8.结论
100例临床实验结果显示，此种促孕气血通关散对治疗不孕不育病症具有显著疗效，其综合症状疗效总有效率分别为97.8％。综合对比该中药疗效确切，使用方便，且在应有过程中未发现明显不良反应和无副作用。

Claims (3)

1.一种治疗不孕不育的中药制剂及其制备方法，其特征在于：有下列中药材制成，酒当归，黄芪，枸杞，淮山药，酒白芍，炒桑寄生，菟丝子，香附子，甘草，黑荆芥穗，制穿山甲，大熟地，五味子等几十种草哟。
2.根据权利要求1所述的一种治疗不孕不育的中药制剂及其制备方法，其特征在于：按照下列重量配比制成，酒当归300g-500g，黄芪500g-1000g，枸杞300g-500g，淮山药300g-500g，酒白芍300g-500g，炒桑寄生150g-300g，菟丝子300g-600g，香附子100g-200g，甘草50g-100g，黑荆芥穗50g-100克，制穿山甲100g-200克，大熟地100g-200g，五味子100g-300g.(此为五公斤配比)。
3.根据权利要求2所述的一种治疗不孕不育的中药制剂及其制备方法，其特征在于：各原料优选重量配比制成，酒当归500克，黄芪1000克，枸杞500克，淮山药500克，酒白芍500克，炒桑寄生300克，菟丝子600克，香附子200克，甘草100克，黑荆芥穗100克，制穿山甲200克，大熟地200克，五味子300克(此为五公斤配比)。
CN201410842773.4A 2014-12-31 2014-12-31 一种治疗不孕不育的中药制剂及其制备方法 Pending CN104491314A (zh)

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Cited By (2)

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Publication number Priority date Publication date Assignee Title
CN104491227A (zh) * 2014-12-31 2015-04-08 闫小旺 一种治疗麦粒肿的中药制剂及其制备方法
CN107648425A (zh) * 2017-11-13 2018-02-02 山西康逸堂生物科技有限公司 一种治疗不孕不育的中药及其制作方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
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尚儒彪: "《武当道医妇科临证灵方妙法》", 31 July 2013, 山西科学技术出版社 *
张玉珍等: ""罗元恺教授治疗不孕不育症学术经验介绍"", 《新中医》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491227A (zh) * 2014-12-31 2015-04-08 闫小旺 一种治疗麦粒肿的中药制剂及其制备方法
CN107648425A (zh) * 2017-11-13 2018-02-02 山西康逸堂生物科技有限公司 一种治疗不孕不育的中药及其制作方法

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Application publication date: 20150408