CN104490946A - Preparation process of uncinata spikemoss herb extract and application thereof in oral cleaning paste and liquid - Google Patents
Preparation process of uncinata spikemoss herb extract and application thereof in oral cleaning paste and liquid Download PDFInfo
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- CN104490946A CN104490946A CN201510001205.6A CN201510001205A CN104490946A CN 104490946 A CN104490946 A CN 104490946A CN 201510001205 A CN201510001205 A CN 201510001205A CN 104490946 A CN104490946 A CN 104490946A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
Abstract
The invention discloses a preparation process of an uncinata spikemoss herb extract and an application thereof in an oral cleaning paste and liquid and relates to an extraction process of active ingredients of uncinata spikemoss herb and an application thereof, which is suitable for demand of industrial production, short in processing period and high in extraction efficiency. The preparation process comprises the following steps: crushing; soaking; heating; concentrating; carrying out backwashing extraction; collecting a pasty material deposited at the bottom and cooling to 15-30 DEG C; evaporating and concentrating; and finishing. In pre-treatment, a state solid-suspension transformation mode, namely powder is soaked to a suspension. An efficient backwashing extraction operation mode is then utilized. In the backwashing extraction operation, the area and time of contact between the raw material and the extracting liquid (ethanol) are effectively increased, so that the extraction effect is enhanced; the active ingredients in the material pre-treated are extracted with the highest efficiency to the maximum extent. The oral cleaning product prepared by the preparation process disclosed by the invention can be used for alleviating swelling and aching of gum and bleeding gums.
Description
Technical field
The invention belongs to Chinese herbal medicine and utilize field, particularly relate to the extraction process to CUIYUNCAO cost-effectively and profit application thereof.
Background technology
CUIYUNCAO meridian distribution of property and flavor: sweet, light, cool; There is heat-clearing and toxic substances removing, dampness removing dredging collateral, preventing phlegm from forming and stopping coughing, effect of hemostasis.For jaundice, dysentery, hyperpyrexia convulsion, cholecystitis, edema, has loose bowels, and spits blood, has blood in stool, rheumatic arthritis, acute mastitis, burn; Inhibitory action is had to staphylococcus aureus.It contains chemical composition of Chinese materia medica: containing diacylglycerol base trimethyl homoserine (diacylglyc-eryltrimethylhomoserine); Flavone, flavonoid glycoside, bisflavone, phenolic compound, ketone, phenols are its main active.
The patent documentation of many sections of Selaginella uncinata extraction methods is had in prior art, as " Selaginella uncinata extraction and its production and use; application number: 2008101985912 ", this case, for the purposes preparing anti-hypoxia or anti-oxidation medicine, proposes the technical scheme of " pulverizing-ethanol water reflux, extract, (merceration, seepage, Soxhlet or circumfluence distillation)-primary extract filtration-ethanol water eluting ".Finally obtain the Related Component required for it.
In addition, title: a kind of Selaginella uncinata extraction and its production and use, application number: the patent documentation of 200910080433.1, discloses another kind of preparation scheme.Its objective is that in extract, total phenolics content is not less than 50%, is more preferably 55%-65%.Its technical scheme comprises: pulverizing, ethanol water extraction, filtration, filtrate reduced in volume, concentrated solution add ethanol make medicinal liquid alcohol content be 45-75%, leave standstill, filter or centrifugal, filtrate or supernatant decompression dealcoholysis, eluting ... final obtained total phenolic acid extract has antiinflammatory, expelling phlegm for arresting cough effect.
The feature that both technical schemes are common is that the preparation process cycle in early stage is longer, extraction usefulness is not high.The former abstraction process adopts the many kinds of measures of dipping class, and its process does not need 2-30 hour not etc..The latter adopts the many kinds of measures such as decoction, alcohol dipping, and process is longer.In extraction usefulness, both are all the schemes of carrying out flooding class to powder, are difficult to be extracted to greatest extent by the effective ingredient (phenols, ketone) in material efficiently.
Summary of the invention
The present invention is directed to above problem, provide a kind of preparation technology of Selaginella uncinata extraction and the application in oral cavity cleaning cream, liquid thereof; Adapt to the requirement of suitability for industrialized production, the process-cycle is short, and extraction efficiency is high.
Technical scheme of the present invention is: comprise CUIYUNCAO sorting, dry operation, then carry out according to the following steps,
1), pulverize; The CUIYUNCAO of described drying is pulverized for 300-450 order particle;
2), soak; Inserted in water by described particle and soak 16-24 hour, the volume ratio of water and particle is 4-10:1; Obtain liquefied mixture;
3), heat; Described liquefied mixture is heated to 80-100 DEG C, keeps 1.5-2 hour; Obtain liquid mixed juice;
4), concentrated; Being concentrated by described liquid mixed juice, is the 10-30% of described liquefied mixture to volume; Obtain thick concentrated solution;
5), recoil is extracted; Described thick concentrated solution is inserted the top of vertical vessel, down spray; The nozzle of opening upwards is set in the middle part of described vertical vessel and/or bottom and/or bottom, by the ethanol of described nozzle to the top-direction ejection aerosolization of described vertical vessel;
6), gather the pasty material of bottom deposit, be cooled to 15-30 DEG C;
7), evaporation and concentration; Remove ethanol in described pasty material, obtain sticky shape Selaginella uncinata extraction;
8), complete.
Described vertical vessel comprises cylindrical body, in described body interior, is provided with at least one circle top mouth spray, at least one circle bottom nozzle, bottom collection storehouse and discharging opening from top to bottom.
Relief valve and rinse mouth is also provided with at the top of described vertical vessel.
In described recoil abstraction process, during work, pressure is 2-2.5 normal atmosphere, and temperature is 60-75 DEG C.
In described Selaginella uncinata extraction, add its quality 0.5-2 emulsifying agent doubly, carry out emulsifying.
Described emulsifying agent is the one or any two or more composite in lecithin, sucrose fatty acid ester, olive oil, sorbitol anhydride monopalmitate, polyoxyethylene sorbitan monostearate.
The application of Selaginella uncinata extraction in oral cavity cleaning cream adopting preparation technology of the present invention to obtain, carries out according to the following steps,
1), the preparation of CUIYUNCAO toothpaste annex solution;
Comprise the component of following weight portion: Selaginella uncinata extraction 7.5-13 part, dehydrated alcohol 12-18 part, Natural menthol 8-12 part, Borneolum Syntheticum 8-12 part, methyl salicylate 20-29 part, first class Oleum Menthae Rotundifoliae 8-12 part, thymol 3.5-8 part, Oleum Caryophylli 12-18 part; Homogeneous phase mixing, airtight standing 20-30h in 20-30 DEG C of environment, obtains CUIYUNCAO toothpaste annex solution;
2), the preparation of mixture A;
Comprise the component of following weight portion: by CUIYUNCAO toothpaste annex solution 8-12 part, deionized water 8-12 part, sorbitol 21-28 part, saccharin sodium 0.15-0.25 part, tertiary sodium phosphate 0.15-0.25 part, calamitas urinae hominis 2-4 part, stir in 35-40 DEG C of environment, obtain mixture A;
3), the preparation of mixture B;
Comprise the component of following weight portion: by calcium hydrogen phosphate 40-50 part, sodium carboxymethyl cellulose 0.7-1.3 part, sodium lauryl sulfate 2-4 part stir, and obtain mixture B;
4), by aforementioned obtained mixture A, mixture B insert in container, then add Mint Essence 0.7-1.3 weight portion, Homogeneous phase mixing; Sealed container, to container vacuum-pumping, keep keeping vacuum-0.092MPa ~ 0.070MPa in container, temperature is 30-38 DEG C, adopts agitating device in container, maintains the stirring of 30-35min, the obtained oral cavity cleaning cream containing Selaginella uncinata extraction.
The application of Selaginella uncinata extraction in mouth cleaning solution adopting preparation technology of the present invention to obtain, comprises the component of following weight portion,
Water 60-70 part, glycerol 8-12 part, sorbitol 8-12 part, castor oil hydrogenated 3-7 part,
Sodium fluoride 0.15-0.25 part, sodium dihydrogen phosphate 0.12-0.18 part, sodium hydrogen phosphate 0.03-0.08 part, Selaginella uncinata extraction 8-12 part;
Menthanol lactic acid ester 0.07-0.12 part, essence 0.15-0.23 part;
Process according to the following steps:
1), heat water to 55-65 DEG C, then add glycerol, sorbitol and castor oil hydrogenated, stir under 55-65 DEG C of condition, obtain mixture C;
2), use the pH value of phosphate adjustment mixture C to 7-8, then add sodium fluoride, sodium hydrogen phosphate, sodium dihydrogen phosphate and Selaginella uncinata extraction under 55-65 DEG C of condition, stir to obtain mixture D;
3), by menthanol lactic acid ester and essence stir at 15-30 DEG C, obtain mixture E;
4), mixture D, mixture E Homogeneous phase mixing, under the pressure condition of the 50-90% of 1 normal atmosphere, keep constant temperature 40-45 DEG C, stir, the obtained mouth cleaning solution containing Selaginella uncinata extraction.
First the present invention carries out the pretreatment of mass to CUIYUNCAO, in pretreatment, the state that have employed is solid-suspension transformation mode, soaks for suspension by broken end, in order to can batch High-efficient Production, all adopts corresponding control in each step of above conversion.Then high efficiency recoil is utilized to extract operating type; Extract in operation in recoil, effectively add the contact area between raw material and extracting solution (ethanol), time, increase effect of extracting; Meanwhile, utilize ethanol effectively to carry out " dissolve, be separated " the phenols in CUIYUNCAO, ketone, to greatest extent by the effective ingredient in material after pretreatment, with in the shortest time under specific technological parameter condition, extract with the highest efficiency.The oral-cavity cleaning products adopting the present invention to prepare contributes to the situation alleviating gingival swelling and pain, gingival hemorrhage.
Accompanying drawing explanation
Fig. 1 is the structural representation of vertical vessel in the present invention,
In figure, 1 is body, and 2 is nozzles, and 3 is mouth sprays, and 4 is Butterworth Hatch, and 5 is relief valve, and 6 is discharging openings, and 7 is bottom collection storehouses.
Detailed description of the invention
Technical scheme of the present invention is: comprise CUIYUNCAO sorting, dry operation, then carry out according to the following steps,
1), pulverize; The CUIYUNCAO of described drying is pulverized for 300-450 order particle;
2), soak; Inserted in water by described particle and soak 16-24 hour, the volume ratio of water and particle is 4-10:1; Obtain liquefied mixture;
3), heat; Described liquefied mixture is heated to 80-100 DEG C, keeps 1.5-2 hour; Obtain liquid mixed juice;
4), concentrated; Being concentrated by described liquid mixed juice, is the 10-30% of described liquefied mixture to volume; Obtain thick concentrated solution;
5), recoil is extracted; Described thick concentrated solution is inserted the top of vertical vessel, down spray; The nozzle of opening upwards is set in the middle part of described vertical vessel and/or bottom and/or bottom, by the ethanol of described nozzle to the top-direction ejection aerosolization of described vertical vessel;
6), gather the pasty material of bottom deposit, be cooled to 15-30 DEG C;
7), evaporation and concentration; Remove ethanol in described pasty material, obtain sticky shape Selaginella uncinata extraction;
8), complete.
As shown in Figure 1, described vertical vessel comprises cylindrical body 1, inner at described body 1, is provided with at least one circle top mouth spray 3, at least one circle bottom nozzle 2, bottom collection storehouse 7 and discharging opening 6 from top to bottom.
Consider for safety and health, the relief valve 5 of Butterworth Hatch 4 can also be set at the top of body 1.
In described recoil abstraction process, during work, pressure is 2-2.5 normal atmosphere, and temperature is 60-75 DEG C.Be convenient to the extraction of phenols, letones.
In described Selaginella uncinata extraction, add its quality 0.5-2 emulsifying agent doubly, carry out emulsifying.
Described emulsifying agent is the one or any two or more composite in lecithin, sucrose fatty acid ester, olive oil, sorbitol anhydride monopalmitate, polyoxyethylene sorbitan monostearate.
The application of Selaginella uncinata extraction in oral cavity cleaning cream adopting preparation technology of the present invention to obtain, carries out according to the following steps,
1), the preparation of CUIYUNCAO toothpaste annex solution;
Comprise the component of following weight portion: Selaginella uncinata extraction 7.5-13 part, dehydrated alcohol 12-18 part, Natural menthol 8-12 part, Borneolum Syntheticum 8-12 part, methyl salicylate 20-29 part, first class Oleum Menthae Rotundifoliae 8-12 part, thymol 3.5-8 part, Oleum Caryophylli 12-18 part; Homogeneous phase mixing, airtight standing 20-30h in 20-30 DEG C of environment, obtains CUIYUNCAO toothpaste annex solution;
2), the preparation of mixture A;
Comprise the component of following weight portion: by CUIYUNCAO toothpaste annex solution 8-12 part, deionized water 8-12 part, sorbitol 21-28 part, saccharin sodium 0.15-0.25 part, tertiary sodium phosphate 0.15-0.25 part, calamitas urinae hominis 2-4 part, stir in 35-40 DEG C of environment, obtain mixture A;
3), the preparation of mixture B;
Comprise the component of following weight portion: by calcium hydrogen phosphate (fineness 600 order, percent of pass 99.8%) 40-50 part, sodium carboxymethyl cellulose 0.7-1.3 part, sodium lauryl sulfate 2-4 part stir, and obtain mixture B;
4), by aforementioned obtained mixture A, mixture B insert in container, then add Mint Essence 0.7-1.3 weight portion, Homogeneous phase mixing; Sealed container, to container vacuum-pumping, keep vacuum-0.092MPa ~ 0.070MPa, temperature is 30-38 DEG C, adopts agitating device in container, maintains the stirring of 30-35min, the obtained oral cavity cleaning cream containing Selaginella uncinata extraction.Evacuation, makes finished surface smooth, even, fine and smooth, ensures to combine between each component more tight simultaneously, avoids dissociating.
The application of Selaginella uncinata extraction in mouth cleaning solution adopting preparation technology of the present invention to obtain, comprises the component of following weight portion,
Water 60-70 part, glycerol 8-12 part, sorbitol 8-12 part, castor oil hydrogenated 3-7 part,
Sodium fluoride 0.15-0.25 part, sodium dihydrogen phosphate 0.12-0.18 part, sodium hydrogen phosphate 0.03-0.08 part, Selaginella uncinata extraction 8-12 part;
Menthanol lactic acid ester 0.07-0.12 part, essence 0.15-0.23 part;
Process according to the following steps:
1), heat water to 55-65 DEG C, then add glycerol, sorbitol and castor oil hydrogenated, stir under 55-65 DEG C of condition, obtain mixture C;
2), the pH value of phosphate adjustment mixture C is used to measure to the extensive reagent paper of 7-8(PH), then sodium fluoride, sodium hydrogen phosphate, sodium dihydrogen phosphate and Selaginella uncinata extraction is added under 55-65 DEG C of condition, stir to obtain mixture D;
3), by menthanol lactic acid ester and essence stir at 15-30 DEG C, obtain mixture E;
4), mixture D, mixture E Homogeneous phase mixing, under the pressure condition of the 50-90% of 1 normal atmosphere, keep constant temperature 40-45 DEG C, stir, the obtained mouth cleaning solution containing Selaginella uncinata extraction.Under this pressure condition, wherein more uniformly " dispersion " in the product for oils and fats state substance.
Be described further the present invention particularly below by embodiment, the rights protection scope of patent of the present invention is including, but not limited to this.
embodiment one
It is 300 order particles that CUIYUNCAO is pulverized; Measure 1 liter; Insert in water and soak 16 hours, the water yield gets 4 liters; Obtain liquefied mixture; Heat to 80 DEG C immediately, keep 2 hours; Obtain liquid mixed juice;
Liquid mixed juice is concentrated, to volume 1.5 liters; Obtain thick concentrated solution;
Recoil is extracted; Thick concentrated solution is inserted the top of vertical vessel, down spray; The nozzle of opening upwards is set at the middle part of vertical vessel and bottom, by the ethanol of nozzle to the top-direction ejection aerosolization of vertical vessel; In recoil abstraction process, during work, pressure is 2.5 normal atmospheres, and temperature is 75 DEG C.Because the phenols in material, ketones component are not soluble in water, ethanol extracts in operation in aforementioned recoil and plays " solvent " effect.
Gather the pasty material of bottom deposit, be cooled to 30 DEG C;
Evaporation and concentration; Remove ethanol in pasty material, obtain sticky shape Selaginella uncinata extraction; It should be noted that, suitably can improve evaporating temperature in the process, reduce water content.But the phenols now in material, ketones component can retain in oils and fats state in sticky shape Selaginella uncinata extraction after evaporation.
Obtained sticky shape Selaginella uncinata extraction contains phenols and the letones of oils and fats state, for better carrying out next step application, can carry out emulsifying processing to it.The phenols of oils and fats state and letones can be made to disperse evenly.
embodiment two
It is 450 order particles that CUIYUNCAO is pulverized; Measure 1 liter; Insert in water and soak 24 hours, the water yield gets 10 liters; Obtain liquefied mixture; Heat to 100 DEG C immediately, keep 1.5 hours; Obtain liquid mixed juice;
Liquid mixed juice is concentrated, to volume 1.1 liters; Obtain thick concentrated solution;
Recoil is extracted; Thick concentrated solution is inserted the top of vertical vessel, down spray; The nozzle of opening upwards is set at the middle part of vertical vessel and bottom, by the ethanol of nozzle to the top-direction ejection aerosolization of vertical vessel; In recoil abstraction process, during work, pressure is 2 normal atmospheres, and temperature is 60 DEG C.
Gather the pasty material of bottom deposit, be cooled to 15 DEG C;
Evaporation and concentration; Remove ethanol in pasty material, obtain sticky shape Selaginella uncinata extraction; It should be noted that, suitably can improve evaporating temperature in the process, reduce water content.But the phenols now in material, ketones component can retain in oils and fats state in sticky shape Selaginella uncinata extraction after evaporation.
Obtained sticky shape Selaginella uncinata extraction contains phenols and the letones of oils and fats state, for better carrying out next step application, can carry out emulsifying processing to it.The phenols of oils and fats state and letones can be made to disperse evenly.
embodiment three
It is 370 order particles that CUIYUNCAO is pulverized; Measure 1 liter; Insert in water and soak 20 hours, the water yield gets 8 liters; Obtain liquefied mixture; Heat to 90 DEG C immediately, keep 1.8 hours; Obtain liquid mixed juice;
Liquid mixed juice is concentrated, to volume 2.7 liters; Obtain thick concentrated solution;
Recoil is extracted; Thick concentrated solution is inserted the top of vertical vessel, down spray; The nozzle of opening upwards is set at the middle part of vertical vessel and bottom, by the ethanol of nozzle to the top-direction ejection aerosolization of vertical vessel; In recoil abstraction process, during work, pressure is 2.2 normal atmospheres, and temperature is 70 DEG C.
Gather the pasty material of bottom deposit, be cooled to 20 DEG C;
Evaporation and concentration; Remove ethanol in pasty material, obtain sticky shape Selaginella uncinata extraction.
Claims (8)
1. a preparation technology for Selaginella uncinata extraction, comprises CUIYUNCAO sorting, dry operation, it is characterized in that, then carry out according to the following steps,
1), pulverize; The CUIYUNCAO of described drying is pulverized for 300-450 order particle;
2), soak; Inserted in water by described particle and soak 16-24 hour, the volume ratio of water and particle is 4-10:1; Obtain liquefied mixture;
3), heat; Described liquefied mixture is heated to 80-100 DEG C, keeps 1.5-2 hour; Obtain liquid mixed juice;
4), concentrated; Being concentrated by described liquid mixed juice, is the 10-30% of described liquefied mixture to volume; Obtain thick concentrated solution;
5), recoil is extracted; Described thick concentrated solution is inserted the top of vertical vessel, down spray; The nozzle of opening upwards is set in the middle part of described vertical vessel and/or bottom and/or bottom, by the ethanol of described nozzle to the top-direction ejection aerosolization of described vertical vessel;
6), gather the pasty material of bottom deposit, be cooled to 15-30 DEG C;
7), evaporation and concentration; Remove ethanol in described pasty material, obtain sticky shape Selaginella uncinata extraction;
8), complete.
2. the preparation technology of a kind of Selaginella uncinata extraction according to claim 1, it is characterized in that, described vertical vessel comprises cylindrical body, in described body interior, is provided with at least one circle top mouth spray, at least one circle bottom nozzle, bottom collection storehouse and discharging opening from top to bottom.
3. the preparation technology of a kind of Selaginella uncinata extraction according to claim 2, is characterized in that, is also provided with relief valve and rinse mouth at the top of described vertical vessel.
4. the preparation technology of a kind of Selaginella uncinata extraction according to claim 1, is characterized in that, in described recoil abstraction process, during work, pressure is 2-2.5 normal atmosphere, and temperature is 60-75 DEG C.
5. the preparation technology of a kind of Selaginella uncinata extraction according to claim 1, is characterized in that, adds its quality 0.5-2 emulsifying agent doubly, carry out emulsifying in described Selaginella uncinata extraction.
6. the preparation technology of a kind of Selaginella uncinata extraction according to claim 5, it is characterized in that, described emulsifying agent is the one or any two or more composite in lecithin, sucrose fatty acid ester, olive oil, sorbitol anhydride monopalmitate, polyoxyethylene sorbitan monostearate.
7. the application of Selaginella uncinata extraction in oral cavity cleaning cream that obtain of the preparation technology of a kind of Selaginella uncinata extraction according to claim 1, is characterized in that, carry out according to the following steps,
1), the preparation of CUIYUNCAO toothpaste annex solution;
Comprise the component of following weight portion: Selaginella uncinata extraction 7.5-13 part, dehydrated alcohol 12-18 part, Natural menthol 8-12 part, Borneolum Syntheticum 8-12 part, methyl salicylate 20-29 part, first class Oleum Menthae Rotundifoliae 8-12 part, thymol 3.5-8 part, Oleum Caryophylli 12-18 part; Homogeneous phase mixing, airtight standing 20-30h in 20-30 DEG C of environment, obtains CUIYUNCAO toothpaste annex solution;
2), the preparation of mixture A;
Comprise the component of following weight portion: by CUIYUNCAO toothpaste annex solution 8-12 part, deionized water 8-12 part, sorbitol 21-28 part, saccharin sodium 0.15-0.25 part, tertiary sodium phosphate 0.15-0.25 part, calamitas urinae hominis 2-4 part, stir in 35-40 DEG C of environment, obtain mixture A;
3), the preparation of mixture B;
Comprise the component of following weight portion: by calcium hydrogen phosphate 40-50 part, sodium carboxymethyl cellulose 0.7-1.3 part, sodium lauryl sulfate 2-4 part stir, and obtain mixture B;
4), by aforementioned obtained mixture A, mixture B insert in container, then add Mint Essence 0.7-1.3 weight portion, Homogeneous phase mixing; Sealed container, to container vacuum-pumping, keep vacuum-0.092MPa ~ 0.070MPa in container, temperature is 30-38 DEG C, adopts agitating device in container, maintains the stirring of 30-35min, the obtained oral cavity cleaning cream containing Selaginella uncinata extraction.
8. the application of Selaginella uncinata extraction in mouth cleaning solution that obtain of the preparation technology of a kind of Selaginella uncinata extraction according to claim 1, is characterized in that, comprise the component of following weight portion,
Water 60-70 part, glycerol 8-12 part, sorbitol 8-12 part, castor oil hydrogenated 3-7 part,
Sodium fluoride 0.15-0.25 part, sodium dihydrogen phosphate 0.12-0.18 part, sodium hydrogen phosphate 0.03-0.08 part, Selaginella uncinata extraction 8-12 part;
Menthanol lactic acid ester 0.07-0.12 part, essence 0.15-0.23 part;
Process according to the following steps:
1), heat water to 55-65 DEG C, then add glycerol, sorbitol and castor oil hydrogenated, stir under 55-65 DEG C of condition, obtain mixture C;
2), use the pH value of phosphate adjustment mixture C to 7-8, then add sodium fluoride, sodium hydrogen phosphate, sodium dihydrogen phosphate and Selaginella uncinata extraction under 55-65 DEG C of condition, stir to obtain mixture D;
3), by menthanol lactic acid ester and essence stir at 15-30 DEG C, obtain mixture E;
4), mixture D, mixture E Homogeneous phase mixing, under the pressure condition of the 50-90% of 1 normal atmosphere, keep constant temperature 40-45 DEG C, stir, the obtained mouth cleaning solution containing Selaginella uncinata extraction.
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| CN113289374A (en) * | 2021-05-21 | 2021-08-24 | 安徽省徽功夫生物科技有限责任公司 | Method for extracting active ingredients from tea |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101357144A (en) * | 2008-09-17 | 2009-02-04 | 暨南大学 | Selaginella uncinata extraction, its preparation method and application |
| CN102579305A (en) * | 2012-03-29 | 2012-07-18 | 安徽两面针·芳草日化有限公司 | Natural medicine toothpaste with saussurea involucrata as major material |
| CN102772912A (en) * | 2012-07-05 | 2012-11-14 | 西安鸿生生物技术有限公司 | Device and method for extracting effective components from natural plant by high-pressure spraying reverse-flow process |
| CN103520010A (en) * | 2013-10-18 | 2014-01-22 | 柳州两面针股份有限公司 | Application of tetrahydropalmatine and naringin in preparing oral care products |
-
2015
- 2015-01-04 CN CN201510001205.6A patent/CN104490946B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101357144A (en) * | 2008-09-17 | 2009-02-04 | 暨南大学 | Selaginella uncinata extraction, its preparation method and application |
| CN102579305A (en) * | 2012-03-29 | 2012-07-18 | 安徽两面针·芳草日化有限公司 | Natural medicine toothpaste with saussurea involucrata as major material |
| CN102772912A (en) * | 2012-07-05 | 2012-11-14 | 西安鸿生生物技术有限公司 | Device and method for extracting effective components from natural plant by high-pressure spraying reverse-flow process |
| CN103520010A (en) * | 2013-10-18 | 2014-01-22 | 柳州两面针股份有限公司 | Application of tetrahydropalmatine and naringin in preparing oral care products |
Non-Patent Citations (1)
| Title |
|---|
| 郑俊霞等: "翠云草总黄酮的提取工艺研究", 《中药材》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113289374A (en) * | 2021-05-21 | 2021-08-24 | 安徽省徽功夫生物科技有限责任公司 | Method for extracting active ingredients from tea |
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