KR20170125191A - Pill using aronia berry and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a pill using aronia berries and a manufacturing method thereof. The pill using aronia berries is manufactured by the following steps: supplying water in which aqueous propolis is diluted in 5-20 parts by weight of aronia berry powder and preparing liquid porridge; primarily fermenting the liquid porridge at the temperature of 25-30 degrees for 1-2 hours; inputting the fermented liquid porridge in a mixer set at the temperature of 25-30 degrees, kneading the same for 1-10 hours and prepare dough; making the dough into pills with the diameter of 2-5 mm; and drying the pills at the temperature of 50-60 degrees for 12-24 hours.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for producing a ring using an aronia berry,

The present invention relates to a ring using Aronia berry and a method for producing the ring, and relates to a ring using Aronia berry which can be made into Aronia berry and propolis by a ring and a method for producing the ring.

Aronia (Aronia) is a shrub native to North America, belonging to the Rosaceae, with small, sour fruits, which ripen in the late summer and fall immediately. The leaves are soft, glazed and light green. These Aronia are widely used in the food industry, and Aronia fruit is used as a variety of foods such as juice, beverage, concentrate, wine, jam, jelly, dried fruit and fruit tea.

These Aronia fruits contain a large amount of saccharides (20%), anthocyanins, polyphenols, vitamins B1 and B2, pantothenic acid, and flavonoids. In particular, anthocyanin and polyphenol contribute to the blood circulation in the human body, and contribute to microvessel permeability, vascular resilience, normalization of blood pressure, and particularly, to provide a positive effect on the microvascularity of the eye, . ≪ / RTI >

Propolis is a lipid-soluble complex obtained from a honeycomb, which is the material used by honeybees to strengthen the honeycomb gap to preserve the honey in the honeycomb. Propolis is a resinous, sticky, rubbery substance that combines wax and resin materials collected from flowers, leaves and buds with bees' own salivary secretions.

There have been many studies on the physiological activity of propolis, and it has shown very high activity in the treatment of cancer, antibacterial, antibacterial, antiviral, anti-inflammatory, antifungal, antioxidant and allergic dermatitis.

Korean Patent Registration No. 10-1236047 discloses a method of producing a ring using Aronia barley powder, which comprises the steps of: preparing Aronia berry having various beneficial effects on the human body and various materials in the form of a circle, Which is a method for producing a ring using an Aronia berry powder.

However, the method of producing the ring using the Aronia barley powder does not contain the propolis component, and thus, there is a problem that the effects of anticancer, antibacterial, antibacterial, antiviral, anti-inflammatory, antifungal and antioxidant are inferior.

A problem to be solved by the present invention is to provide a pharmaceutical composition which comprises Aruonia berry and Propolis as a ring to be used as a medicament using Aronia berry which is highly effective for anti-cancer, antibacterial, antibacterial, antiviral, anti-inflammatory, antifungal, And a method of manufacturing the same.

In order to solve the above-mentioned problems, the present invention provides a method for producing a water-soluble propolis, comprising: (a) supplying water diluted with water-soluble propolis to 5 to 20 parts by weight of an Aronia barley powder, (b) primary fermenting the liquid phase at a temperature of 25 to 30 for 1 to 2 hours; (c) placing the fermented liquid phase in an agitator set at a temperature of 25 to 30 and kneading the mixture for 1 to 10 hours; (d) making the dough into a circle having a diameter of about 2 to 5 mm, and (e) drying the ring at a temperature of 50 to 60 for 12 to 24 hours. Method can be provided.

The method of manufacturing a ring using Aronia berry may further comprise the step of adding 3 to 15 parts by weight of a canola powder, 3 to 8 parts by weight of a leaf powder, and 5 to 15 parts by weight of a canola powder before the step (b) The step may further include a step of secondary fermenting the dough to a temperature of 20 to 25 before the step.

In addition, the method for producing a pearl using Aronia berry is characterized in that before step (c), 2 to 10 parts by weight of a root powder, 5 to 10 parts by weight of a ginger powder, 6 to 15 parts by weight of a ginger powder, 6 to 9 parts by weight of chrysanthemum powder, 7 to 9 parts by weight of top powder, 3 to 6 parts by weight of garlic powder, 3 to 6 parts by weight of cordierite powder, 7 to 9 parts by weight of brown rice powder, 2 to 4 parts by weight of pine needle powder Mixing 2 to 5 parts by weight of the yacon powder, 2 to 4 parts by weight of the beet root powder and 1 to 3 parts by weight of the zeolite powder with alkali reducing water and mixing the mixture with the first fermented liquid phase porridge .

In addition, the method for producing a ring using Aronia berry is characterized in that 0.5 to 1.5 parts by weight of green tea powder, 0.5 to 1.5 parts by weight of apple peel powder, 0.5 to 1.5 parts by weight of tangerine husk powder, 0.5 to 1.5 parts by weight of mulberry leaf powder 0.5 to 1.5 parts by weight of spinach powder and 0.5 to 1.5 parts by weight of charcoal powder to the primary fermented liquid phase.

The method of manufacturing a ring using Aronia berry further comprises coating the surface of the ring with a coating solution after the step (e), wherein the coating solution contains 40 brix of propolis solution, citric acid, green tea extract, ginger juice , Onion juice, aloe extract, and red ginseng solution, and the coating liquid may be used in an amount of 10 to 35 wt% (based on the weight of the ring).

The water-soluble propolis is extracted with an alcohol-free water-soluble extraction method, and the propolis is diluted with the water at a ratio of 1:10 to 2:10. The water-free alcoholic extraction method comprises: pulverizing the propolis raw material; The pulverized propolis raw material is mixed with a solution in which alcohol and water are mixed in a ratio of 6: 4 to 9: 1, and flavonoid (FLAVONOID), terpenoid, polysaccharide and mineral ingredient Extracting the extracted extract; Subjecting the extract to primary filtration; Storing the primary filtered extract at a temperature of minus 10 degrees Celsius to minus 30 degrees Celsius for 24 hours to 72 hours to remove wax, fat and resin components from the primary filtered extract; Secondary filtration of the dewatered product; Concentrating the secondary filtered product at a temperature of 40 to 80 degrees Celsius and a vacuum pressure of 600 to 740 mmHg; Mixing the concentrated concentrate with a dissolving solution mixed with a pH 7.8 to 8.5 weak alkaline water and sodium hydrogencarbonate (NaHCO3) in a ratio of 7: 3 to 9: 1; Stirring the mixture in which the concentrate and the dissolution solution are mixed for 6 hours to 24 hours; A step of subjecting the agitated mixture to a third filtration, and a step of drying the third filtered mixture to prepare a powder.

Also, it is possible to provide a ring using Aronia berry prepared by the above production method.

According to the embodiment of the present invention, the ring using Aronia berry and the method of producing the same have the effect of enhancing anticancer, antibacterial, antibacterial, antiviral, anti-inflammatory, antifungal and antioxidant.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a flowchart sequentially illustrating a method of manufacturing a ring using Aronia berry according to an embodiment of the present invention; FIG.

Hereinafter, the description of the present invention with reference to the drawings is not limited to a specific embodiment, and various transformations can be applied and various embodiments can be made. It is to be understood that the following description covers all changes, equivalents, and alternatives falling within the spirit and scope of the present invention.

In the following description, the terms first, second, and the like are used to describe various components and are not limited to their own meaning, and are used only for the purpose of distinguishing one component from another component.

Like reference numerals used throughout the specification denote like elements.

As used herein, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. It is also to be understood that the terms " comprising, "" comprising, "or" having ", and the like are intended to designate the presence of stated features, integers, And should not be construed to preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, or combinations thereof.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is a flowchart sequentially illustrating a method of manufacturing a ring using Aronia berry according to an embodiment of the present invention.

Referring to FIG. 1, a method for producing a pearl using Aronia berry is provided by supplying water diluted with water-soluble propolis to a Aronia berry powder, a Yoonmeek powder, a lobule powder, (S20), a step of fermenting the first stage of fermentation (S20), triple root powder, gugija powder, safflower root powder, licorice powder, chungkukjang powder, top powder, garlic powder, (S30) mixing the first and second fermented green tea juice with the alkaline reducing water (S30), mixing the green tea powder, Spinning powder and charcoal powder (S40), a step of making a dough (S50) while agitating the primary fermented liquid phase with a stirrer, a step of secondary fermenting the dough (S60), a step The steps for creating the (S70), may include a step (S90) for coating a surface with a ring step (S80), and the coating solution to dry the ring.

(S10) in which the water-diluted water-soluble propolis is diluted in the Aronia barley powder, the yogurt powder, the lobule powder and the sorbit powder is 5 to 20 parts by weight of aronia berry powder, 3 to 15 parts by weight of the yogurt powder , 10 to 20 parts by weight of water diluted with water-soluble propolis may be added to 3 to 8 parts by weight of the leaf blade, 5 to 15 parts by weight of the leaf powder, and then the liquid die can be formed.

Here, alkali reduced water may be used instead of water. Alkali-reduced water is water that is treated with energy such as electrolysis of water, electrostatic field, magnetic field and ultrasonic waves, or ionized water using specific materials. Alkali-reduced water is produced by kneading with a liquid-phase porridge stirrer, and the odor of the dough disappears, and the dough can be prevented from resting.

Propolis can be diluted with water in a ratio of 1:10 to 2:10 to propolis extracted with a non-alcoholic aqueous extraction method. Propolis consists of flavonoid, Caffeic acid Phenethyl ester, Artepillin-c and Gterpen. Propolis has effects such as active noxious oxygen elimination, anti-inflammation, antibacterial, antiviral, immune enhancement, anti-cancer, antiallergic, inhibition of Helicobacter pylori.

The alcohol-free water-soluble extraction method comprises a step (S110) of pulverizing a propolis raw material, mixing the pulverized propolis raw material with a mixed solution of alcohol and water in a ratio of 6: 4 to 9: 1, (S120), extracting the first extract (S130), extracting the first filtered extract at a temperature of minus 10 degrees Celsius to minus 30 degrees Celsius (S120), extracting the extract containing FLAVONOID, TERPENOID, polysaccharide and mineral components (Step S140) of separating the wax, fat and resin components from the primary filtered extract, storing the resulting mixture in a temperature condition of 24 hours to 72 hours, Filtering the resultant filtered product at a temperature of 40 to 80 degrees Celsius and a vacuum pressure of 600 to 740 mmHg at step S160, filtering the concentrated condensate at a pH of 7.8 to 8.5 with weak alkaline water and sodium hydrogen carbonate (NaHCO3) 3 to 9: 1 < RTI ID = 0.0 > (S180) mixing the concentrated mixture with the dissolving solution (S180), stirring the mixed mixture for 6 hours to 24 hours (S190), and performing the third filtered And drying the mixture to prepare it in powder form (S191).

The step (S110) of pulverizing the propolis raw material may be a step of pulverizing the propolis raw material. The step of pulverizing the propolis raw material (S110) may pulverize the propolis raw material to a size of 1 to 100 mesh.

The powdered propolis raw material is mixed with a solution mixed with alcohol and water in a ratio of 6: 4 to 9: 1, and flavonoid (FLAVONOID), terpenoid, polysaccharide and mineral ingredient In step S120 of extracting the contained extract, 100 g of the pulverized propolis raw material is mixed with 500 g of the mixed solution of alcohol and water in a ratio of 6: 4 to 9: 1 through the step of pulverizing the propolis raw material (S110) . In this case, the propolis raw material and the solution may be mixed at a ratio of about 1: 2 to 1: 5. Thereafter, extracts containing flavonoids, terpenoids, polysaccharides and mineral components can be extracted using a non-alcoholic water-based process.

The extract may be primary filtered (S130) by first filtering the extracted extract. The step of performing the primary filtration (S130) of the extract may be performed through a microfilter. In this case, a filter having a hole size of 10 to 600 mu m can be used as the micro filter.

In addition, the step (S130) of primary filtration of the extract may be performed by a filter press (pressure: 2.0 kg / cm 2 or less, filter cloth: 800 x 800 x 40 mm).

The step of extracting wax, fat and resin components from the primary filtered extract (S140) by storing the primary filtered extract at a temperature of minus 10 degrees to minus 30 degrees and for 24 to 72 hours, The filtered extract may be stored at a temperature of minus 10 degrees Celsius to minus 30 degrees Celsius for 24 hours to 72 hours to remove the wax, fat and resin components from the primary filtered extract. The step of extracting wax, fat and resin components from the primary filtered extract (S140) by storing the primary filtered extract at a temperature of minus 10 degrees to minus 30 degrees and for 24 to 72 hours, The filtered extract can be stored for 60 hours at a temperature of minus 15 degrees Celsius to remove wax, fat and resin components from the primary filtered extract.

In the step of performing the secondary filtration (S150) on the desalted result, the desalted product may be subjected to the secondary filtration. The step of performing the secondary filtration (S150) of the desalted product may be performed through a microfilter. In this case, a filter having a hole size of 5 to 300 mu m can be used as the micro filter.

In addition, the step of performing secondary filtration (S150) on the desalted product may be performed by a filter press (pressure: 1.5 kg / cm 2 or less, filter cloth: 800 x 800 x 40 mm).

(S160) of concentrating the secondary filtered product at a temperature of 40 to 80 degrees Celsius and a vacuum pressure of 600 to 740 mmHg (S160) is performed at a temperature of 40 to 80 degrees Celsius and a vacuum of 600 to 740 mmHg It can be concentrated under pressure.

In addition, the step (S160) of concentrating the secondary filtered product at a temperature of 40 to 80 degrees Celsius and a vacuum pressure of 600 to 740 mmHg (S160) may be performed at a temperature of 65 degrees Celsius and a vacuum pressure of 640 mmHg Lt; / RTI >

(S170) mixing the concentrated concentrate with a dissolution solution having a pH of 7.8 to 8.5 mixed with weak alkaline water and sodium hydrogencarbonate (NaHCO3) in a ratio of 7: 3 to 9: 1 (S170) Alkaline water and sodium hydrogencarbonate (NaHCO3) in a ratio of 7: 3 to 9: 1.

In addition, the step (S170) of mixing the concentrated concentrate with a dissolving solution having a pH of 7.8 to 8.5 mixed with weak alkaline water and sodium hydrogencarbonate (NaHCO3) in a ratio of 7: 3 to 9: 1 (S170) Alkaline water and sodium hydrogencarbonate (NaHCO3) can be mixed with a dissolving solution mixed in an 8: 2 ratio. Thus, the pH of the concentrated concentrate is changed from slightly acid to alkaline, so that the concentrated concentrate may have improved hydrophilicity with water.

Stirring the mixed mixture of the concentrate and the dissolution solution for 6 to 24 hours (S180) may agitate the mixture of the concentrate and the dissolution solution for 6 to 24 hours. In addition, the step (S180) of stirring the mixed mixture of the concentrate and the dissolving solution for 6 to 24 hours may agitate the mixed mixture of the concentrate and the dissolving solution for 12 hours.

For reference, it is recommended that the mixture containing the concentrate and the dissolving solution is stirred for at least 12 hours. By stirring for more than 12 hours, the concentrate and the dissolving solution can be maintained in a state of being well mixed with each other.

The stirred mixture may be subjected to tertiary filtration (S190). The stirred mixture may be subjected to tertiary filtration. The step of thirdly filtering the stirred mixture (S190) can be filtered through a microfilter. In this case, a filter having a hole size of 2 to 150 mu m can be used as a micro filter.

In addition, the step (S190) of tertiary filtration of the extract may be carried out by a filter press (pressure: 1.0 kg / cm 2 or less, filter cloth: 800 x 800 x 40 mm).

The step of drying the tertiary filtered mixture and preparing it in powder form (S191) can be obtained in the form of a powder by drying the tertiary filtered mixture. When the step of drying the tertiary filtered mixture is completed, a small particle size powder can be obtained.

Accordingly, the propolis produced can be in powder form with uniform properties and uniform particle size.

The propolis water-soluble powder according to the embodiment of the present invention is highly effective in enhancing the health of the recipient because of its high absorption rate in the body.

In addition, the propolis water-soluble powder according to the embodiment of the present invention is characterized in that the taste is smooth and the ingestion is easy, unlike the fat-soluble propolis.

Aronia berry is known to have excellent efficacy in cardiovascular diseases, various cancers, dementia, diabetes, liver disease, gastrointestinal diseases, neurological diseases, vision disorders, obesity, infertility, rheumatism, sexual function, urinary diseases, viral diseases, It contains a large amount of sugars, anthocyanins, vitamin B1, vitamin B2, pantothenic acid, flavonoids, and the like.

In particular, anthocyanins contained in Aronia berry are superior to antioxidants in protecting not only the body cells but also the immune system.

In addition, anthocyanin pigments are known to dissolve / excrete the waste materials in blood vessels to prevent heart diseases and strokes, purify blood, prevent and treat visual disturbances such as eye fatigue and visual loss.

Yongan is a dead skin of Dimocarpus longan Loureiro (aphanx and Sapindaceae), which is effective for postpartum edema, anemia, hyperhidrosis, indigestion and anticancer action.

Leaves are leaves and a young stem dried medicine (Korea) of Artemisia argyi Lev. Et Vant., A. princeps Pamp. Var. Orientlis Hara or A. montana Pamp. It makes the uterine and lower abdomen weak and bleeding uterine hemorrhage, bleeding during pregnancy, hematemesis, nosebleed, nausea and hemorrhage reaction because it warms the blood of 气血 and gyeongmaek (经脉). In addition, it is effective for symptoms such as coldness and pain in abdomen, weakness in menstruation, menstrual cramps and subarachnments, and eczema and skin itching.

It is a fruit of Xanthium strumarium L., and it is effective for sinusitis, rhinitis, headache, fever, cough, paralysis of the extremities, irritability, skin itching, otitis media.

The liquid fermentation step (S20) may be performed for 1 to 2 hours at a temperature of 25 to 30.

Mixed with alkaline reducing water, either one of the three kinds of root powder, ginger powder, ginger powder, licorice powder, chrysanthemum powder, top powder, garlic powder, kelp powder, brown rice powder, pine leaf powder, yacon powder, beetroot powder, (S30) of 2 to 10 parts by weight of the root root powder, 5 to 10 parts by weight of the ginger powder, 6 to 15 parts by weight of the ginger root powder and 5 to 10 parts by weight of the licorice powder 6 to 9 parts by weight of chrysanthemum powder, 7 to 9 parts by weight of top powder, 3 to 6 parts by weight of garlic powder, 3 to 6 parts by weight of cordierite powder, 7 to 9 parts by weight of brown rice powder, 2 to 4 parts by weight of pine needle powder, 2 to 5 parts by weight of yacon powder, 2 to 4 parts by weight of beet root powder and 1 to 3 parts by weight of western blot powder may be mixed with alkaline reducing water and mixed into the primary fermented liquid phase porridge. Mixed with alkaline reducing water, either one of the three kinds of root powder, ginger powder, ginger powder, licorice powder, chrysanthemum powder, top powder, garlic powder, kelp powder, brown rice powder, pine leaf powder, yacon powder, beetroot powder, (S30) mixing 2.5 to 5.0 parts by weight of seaweed, 2.0 to 5.0 parts by weight of sea tangle, 3.0 to 4.0 parts by weight of red pepper and 2.0 to 4.0 parts by weight of acacia are further mixed .

It has excellent effect on prevention of adult diseases because dietary roots contain sulfur, nitrogen, potassium, iron, manganese, zinc and saponin.

Gugija has non-specific immune enhancing effect, hematopoietic action, cholesterol lowering action, anti-hepatic action, blood pressure lowering, blood glucose lowering, growth promotion and anti-cancer action.

The root of Seokjipang has a function to strengthen kidney, heart, liver function.

Licorice is effective for detoxification, hepatitis, urticaria, dermatitis, eczema, etc. It also has effects on Jinhae, Gadam, muscle relaxation, diuretic effect.

Chungkukjang is effective in preventing cancer, preventing dementia and improving constipation.

It has a good effect on vascular diseases such as prevention of aging, prevention of adult diseases, hypertension.

Garlic powder has the effect of removing food poisoning bacteria and Helicobacter pylori, and improving immunity.

Hwasungcho has the effects of inflammatory diseases, blood circulation improvement and detoxification.

Brown rice is abundant in dietary fiber, and has the effect of preventing the treatment and the absence of diabetes.

Pine needles can prevent liver, stomach and circulatory diseases.

Yacon is rich in dietary fiber, which is good for improving constipation, and it contains fructo-oligosaccharide, which is good for preventing diabetes.

Beetroot is abundant in calcium, manganese, iron, vitamin C and folic acid, and is effective in erythropoiesis, constipation, cancer, stones removal, anemia treatment.

Seomyeongtae anthocyanin compounds help the collagen function, giving skin elasticity and can prevent stains.

Kelp and elevation can enhance the synergistic effect of antioxidant and antimutagenic effects, and the red pepper seeds are rich in 켑 cisin and vitamin A, D, which promote the production of endorphin, have.

The step (S40) of spraying any one of green tea powder, apple peel powder, tangerine peel powder, mulberry leaf powder, spinach powder and charcoal powder to the first fermented liquid phase porridge comprises 0.5 to 1.5 parts by weight of green tea powder, 0.5 to 1.5 parts by weight of apple peel powder 0.5 to 1.5 parts by weight of mulberry leaf powder, 0.5 to 1.5 parts by weight of mulberry leaf powder, 0.5 to 1.5 parts by weight of spinach powder, and 0.5 to 1.5 parts by weight of charcoal powder are added to the first fermented liquid phase I can sprinkle it.

Green tea helps catechin to release waste products and heavy metals, and polyphenols help adsorb nicotine to the outside.

The apple peel has the effect of preventing the antioxidant activity and aging due to the polyphenol ingredient called quercetin.

The tangerine peel contains a large amount of vitamins, which is good for fatigue recovery and immunity enhancement.

Mulberry leaves lowers hypertension and has an excellent antioxidant effect.

Spinach contains a large amount of folic acid and vitamins A and C, and is effective in preventing gastrointestinal irrigation, anemia and dementia.

Charcoal removes harmful germs and gases in the intestines, which has the effect of smoothly moving the intestines.

The first fermented liquid phase is stirred with a stirrer while the dough is formed (S50). The dough can be made by stirring the liquid fermented in a primary fermenter in a stirrer.

The step of secondary fermenting the dough (S60) allows the dough to be fermented at a temperature of 20 to 25 seconds.

The step of making the dough into a circle (S70) can be made into a circle having a diameter of about 2 to 5 mm. The step of making the dough into a ring (S70) can be made into a sphere-shaped circle by putting a dough into a sphere-shaped mold having a diameter of about 2 to 3 mm, or by rolling it between the palms of two hands.

The step of drying the ring (S80) may be carried out by drying the ring at a temperature of 50 to 60 for 12 to 24 hours, thereby forming a solid state having a constant strength.

The step of coating the surface of the ring with the coating liquid (S90) may coat the surface of the circle with the coating liquid.

The coating solution can be prepared by mixing 40 brix of propolis solution with citric acid, green tea extract, ginger juice, onion juice, aloe extract and red ginseng solution.

The propolis solution, citric acid, green tea extract, ginger juice, onion juice, aloe extract and red ginseng extract have the effect of preventing the rotting of the circle and preventing food poisoning.

The coating liquid may be used in an amount of 10 to 35 wt.% Based on the weight of the circle, and a spraying method in which the liquid is sprayed into the sprayer may be used.

Propolis may provide a bioactive effect such as antimicrobial, (antibacterial, antiviral) antioxidant, immune function, and the like.

Propolis is a material made by mixing honey bees and resin materials collected from flowers, leaves and leaf blades of a tree with bees and saliva. It is made of 150 ~ 180 volatile substances and phenol It is a compound such as flavones, flavanones, and flavonols. It is usually in a liquid state in the range of 60 to 70, and has a property of melting in a temperature of 100 or more.

Green tea extract inhibits the growth and growth of bacteria through the anti-inflammatory action of tannin contained in green tea.

In addition, catechin in green tea has strong antioxidant ability and can exterminate Salmonella, Vibrio, and pathogenic Escherichia coli.

Onion juice contains the quercetin component, which inhibits the growth of bacteria causing food poisoning such as Salmonella.

Citric acid changes the urine to alkaline state, so it prevents the occurrence of stones.

Ginger juice prevents cholesterol buildup in blood vessels and can promote blood circulation.

The aloe extract has strong antimicrobial activity against bacteria and fungi, contains aloe tin which neutralizes toxins, has an effect on ulcers, contains aloe vera and alomitin, and has high anticancer effect.

Red ginseng has antidiabetic and anticancer effects, strengthens the heart, and regulates blood pressure.

[Example 1: Ring with the surface of the ring coated with a coating solution]

A step of making a liquid phase (S10), a step of fermenting the liquid phase (S20), a step of making a liquid fermentation (S20) The mixture is mixed with any one of alginate powder, ginger powder, liquorice powder, licorice powder, chrysanthemum powder, top powder, garlic powder, horseradish powder, brown rice powder, pine leaf powder, yacon powder, beetroot powder, (S30) of spraying any one of the green tea powder, the apple peel powder, the orange peel powder, the mulberry leaf powder, the spinach powder and the char powder in the first fermented liquid phase, (Step S50), a step of fermenting the dough (S60), a step of making the dough into a ring (S70), a step of drying the ring (S80), and a step of drying the ring Coating liquid (S90). ≪ RTI ID = 0.0 >

[Example 2: circle not coated with coating liquid]

In the manufacturing method of Example 1, except for the step (S90) of coating the surface of the ring with the coating liquid,

[Experiments: Antimicrobial activity test]

In order to confirm the antibacterial activity of the ring products prepared in Examples 1 and 2, the disk diffusion method (Kirby-Bauer method) was used to carry out the inspection as follows.

2 g of the product was dissolved in 100 ml of water to prepare a sample. 0.1 g of each sample was taken and absorbed into a paper disk (Advantec, Japan) having a diameter of 10 mm for 30 minutes. Then, the fungus was cultured for 27 to 35 hours And the diameter of the clear zone was measured. The results are shown in Table 1 below.

Muller Hinton Agar (Difco, USA) medium was poured into a 4 mm thick watch glass and cooled to room temperature. Bacillus cereus was used as a fungus.

Bacillus cereus was cultured using Sabouraud Dextrose Agar (Difco, USA) medium.

The test strains were plated on Trypticase Soy Agar and cultured for 18 hours. Single colonies were loosely separated and suspended in 4 ml of sterilized saline. The cells were plated on a 0.5 McFarland standard OD (Optical Density).

The bacteria were spread on the surface of the medium with a sterilized cotton swab and dried for about 5 minutes.

Table 1

[Antibacterial activity results of Examples 1 and 2]

As shown in Table 1, there was no change in the diameter of the clear zone with time since Example 1 had no antibacterial activity.

However, in the case of Example 2, it can be seen that as the time is hardened, the diameter of the clear zone gradually increases.

From this, it was proved that the antimicrobial activity of the ring coated with the coating solution prepared by mixing the propolis solution with citric acid, green tea extract, ginger juice, onion juice, aloe extract and red ginseng solution was excellent.

While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, It will be clear to the person.

Claims (7)

(a) supplying 10 to 20 parts by weight of water diluted with water-soluble propolis to 5 to 20 parts by weight of an Aronia barley powder, followed by making a liquid dough;
(b) primary fermenting the liquid phase at a temperature of 25 to 30 for 1 to 2 hours;
(c) placing the fermented liquid phase in an agitator set at a temperature of 25 to 30 and kneading the mixture for 1 to 10 hours;
(d) making the dough into a circle having a diameter of about 2 to 5 mm and
(e) drying the ring at a temperature of 50 to 60 for 12 to 24 hours. The method according to claim 1,
Before the step (b)
Adding 3 to 15 parts by weight of ylang yam powder, 3 to 8 parts by weight of the leaf powder and 5 to 15 parts by weight of the powdery kaolin powder, and
Prior to step (d)
Further comprising the step of subjecting the dough to a secondary fermentation at a temperature of 20 to 25 ° C. The method according to claim 1,
Prior to step (c)
2 to 10 parts by weight of triangular root powder, 5 to 10 parts by weight of ginger powder, 6 to 15 parts by weight of seed ginger root powder, 5 to 10 parts by weight of licorice powder, 6 to 9 parts by weight of chrysanthemum powder, 7 to 9 parts by weight of top powder, 3 to 6 parts by weight of garlic powder, 3 to 6 parts by weight of cordierite powder, 7 to 9 parts by weight of brown rice powder, 2 to 4 parts by weight of pine needle powder, 2 to 5 parts by weight of yacon powder, 2 to 4 parts by weight of beet root powder, And mixing 1 to 3 parts by weight of Seomunghwa powder with alkali reducing water, and mixing the mixture with the first fermented liquid phase porridge. The method according to claim 1,
Prior to step (c)
0.5 to 1.5 parts by weight of green tea powder, 0.5 to 1.5 parts by weight of apple peel powder, 0.5 to 1.5 parts by weight of tangerine peel powder, 0.5 to 1.5 parts by weight of mulberry leaf powder, 0.5 to 1.5 parts by weight of spinach powder and 0.5 to 1.5 parts by weight of charcoal powder Further comprising the step of spraying any one of the first fermented liquid to the porridge of the liquid fermentation. The method according to claim 1,
After the step (e)
Coating the surface of the ring with a coating liquid,
The coating solution is prepared by mixing 40 brix of propolis solution with citric acid, green tea extract, ginger juice, onion juice, aloe extract and red ginseng solution,
Wherein the coating liquid is used in an amount of 10 to 35 wt% (based on the weight of the ring). The method according to claim 1,
The water-soluble propolis is extracted with an alcohol-free water-soluble extraction method, and the propolis is diluted in the water at a ratio of 1:10 to 2:10,
The non-alcoholic aqueous extraction method
Pulverizing the propolis raw material;
The pulverized propolis raw material is mixed with a solution in which alcohol and water are mixed in a ratio of 6: 4 to 9: 1, and flavonoid (FLAVONOID), terpenoid, polysaccharide and mineral ingredient Extracting the extracted extract;
Subjecting the extract to primary filtration;
Storing the primary filtered extract at a temperature of minus 10 degrees Celsius to minus 30 degrees Celsius for 24 hours to 72 hours to remove waxes, fats and resin components from the primary filtered extract;
Secondary filtration of the dewatered product;
Concentrating the secondary filtered product at a temperature of 40 to 80 degrees Celsius and a vacuum pressure of 600 to 740 mmHg;
Mixing the concentrated concentrate with a dissolving solution mixed with a pH 7.8 to 8.5 weak alkaline water and sodium hydrogencarbonate (NaHCO3) in a ratio of 7: 3 to 9: 1;
Stirring the mixture in which the concentrate and the dissolution solution are mixed for 6 hours to 24 hours;
Tertiary filtration of the stirred mixture; and
And drying the third filtered mixture to prepare a powder. The method of producing a pearl using an Aronia berry according to claim 1, 9. A process for producing a fermentation product by using the Aronia berry prepared by the method of any one of claims 1 to 6.

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