CN104490946B - A kind of preparation technology of Selaginella uncinata extraction and its application in oral cleaning cream, liquid - Google Patents
A kind of preparation technology of Selaginella uncinata extraction and its application in oral cleaning cream, liquid Download PDFInfo
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- CN104490946B CN104490946B CN201510001205.6A CN201510001205A CN104490946B CN 104490946 B CN104490946 B CN 104490946B CN 201510001205 A CN201510001205 A CN 201510001205A CN 104490946 B CN104490946 B CN 104490946B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
Abstract
A kind of preparation technology of Selaginella uncinata extraction and its application in oral cleaning cream, liquid.It is related to the extraction process to Uncinata Spikemoss Herb cost-effectively and its profit application.The requirement of industrialized production is adapted to, the process-cycle is short, extraction efficiency is high.The present invention is carried out according to the following steps, is crushed；Immersion；Heating；Concentration；Recoil is extracted；The pasty material of bottom deposit is gathered, 15 30 DEG C are cooled to；It is concentrated by evaporation；Finish.In pretreatment, the solid suspension transformation mode of state is employed, i.e., is suspension by powder immersion.Then operating type is extracted using efficient recoil；In operation is extracted in recoil, raw material and extract solution are effectively increased（Ethanol）Between contact area, the time, increase effect of extracting；To greatest extent by the active ingredient in material after pretreatment, extracted with highest efficiency.The oral-cavity cleaning products prepared using the present invention help to alleviate swelling and aching of gum, the situation of bleeding gums.
Description
Technical field
Field is utilized the invention belongs to Chinese herbal medicine, more particularly to the extraction process and its profit to Uncinata Spikemoss Herb cost-effectively should
With.
Background technology
Uncinata Spikemoss Herb meridian distribution of property and flavor：It is sweet, light, it is cool；With clearing heat and detoxicating, dampness removing dredging collateral, preventing phlegm from forming and stopping coughing, effect of hemostasis.With
In jaundice, dysentery, hyperpyretic convulsion, cholecystitis, oedema, diarrhea is spitted blood, had blood in stool, rheumatic arthritis, acute mastitis, burn；To gold
Staphylococcus aureus have inhibitory action.It contains chemical composition of Chinese materia medica：The trimethyl homoserine of base containing diacylglycerol
(diacylglyc-eryltrimethylhomoserine)；Flavones, flavonoid glycoside, biflavone, phenolic compound, ketone, phenols
For its main active.
The patent document of many Selaginella uncinata extraction methods is there are in the prior art, such as " Selaginella uncinata extraction and its system
Preparation Method and purposes, application number：2008101985912 ", the case is proposed for the purposes for preparing anti anoxia or anti-oxidation medicine
" crushing-ethanol water refluxing extraction（Cold soaking, seepage, Soxhlet or circumfluence distillation）- primary extract filtering-ethanol is water-soluble
The technical scheme of liquid elution ".Finally give the Related Component required for it.
In addition, title：A kind of Selaginella uncinata extraction and its production and use, application number：200910080433.1
Patent document, discloses another preparation scheme.It is not less than 50% the purpose is to total phenolics content in extract, more preferably
55%-65%.Its technical scheme includes：Crush, ethanol water is extracted, filter, filtrate decompression is concentrated, concentrate adds ethanol to make medicine
Liquid alcohol content is 45-75%, standing, filtering or centrifugation, filtrate or supernatant decompression dealcoholysis, the final obtained total phenol of elution ...
Sour extract has anti-inflammatory, expelling phlegm and arresting coughing effect.
The characteristics of both technical schemes are common is that the early stage preparation process cycle is longer, it is not high to extract efficiency.The former carries
Take process using many kinds of measures of dipping class, its process is needed 2-30 hours,.The latter is a variety of using decoction, alcohol dipping etc.
Measure, process is longer.In terms of efficiency is extracted, both of which is the scheme that dipping class is carried out to powder, it is difficult to efficiently by material
In active ingredient（Phenols, ketone）Extract to greatest extent.
The content of the invention
The present invention for problem above there is provided a kind of preparation technology of Selaginella uncinata extraction and its oral cleaning cream,
Application in liquid；The requirement of industrialized production is adapted to, the process-cycle is short, extraction efficiency is high.
The technical scheme is that：Process including being sorted to Uncinata Spikemoss Herb, dry, then carry out according to the following steps,
1）, crush；It is 300-450 mesh particles that the Uncinata Spikemoss Herb of the drying, which is crushed,；
2）, immersion；The particle is inserted in water and soaked 16-24 hours, the volume ratio of water and particle is 4-10:1；Obtain liquid
State mixture；
3）, heating；The liquefied mixture is heated up to 80-100 DEG C, kept for 1.5-2 hours；Obtain liquid mixed juice；
4）, concentration；By liquid mixed juice concentration, to the 10-30% that volume is the liquefied mixture；Obtain and slightly concentrate
Liquid；
5）, recoil extract；The thick concentrate is inserted to the top of vertical vessel, down sprayed；In the vertical vessel
Middle part and/or bottom and/or bottom the nozzles of opening upwards is set, by the nozzle to the top of the vertical vessel
Portion direction sprays the ethanol of aerosolization；
6）, collection bottom deposit pasty material, be cooled to 15-30 DEG C；
7）, be concentrated by evaporation；Ethanol in the pasty material is removed, sticky shape Selaginella uncinata extraction is obtained；
8）, finish.
The vertical vessel includes cylindrical body, in the body interior, from top to bottom provided with least one circle top spray
Mouth, at least one circle bottom nozzle, bottom collection storehouse and discharging opening.
Safety valve and rinse mouth are additionally provided with the top of the vertical vessel.
In the recoil abstraction process, pressure is 2-2.5 standard atmospheric pressure during work, and temperature is 60-75 DEG C.
The emulsifying agent of 0.5-2 times of its quality is added in the Selaginella uncinata extraction, emulsification treatment is carried out.
The emulsifying agent is lecithin, sucrose fatty ester, olive oil, sorbitol anhydride monopalmitate, polyoxyethylene mountain
One kind or any two or more compoundings in pears alcohol acid anhydride monostearate.
Using the present invention preparation technology made from application of the Selaginella uncinata extraction in oral cleaning cream, according to the following steps
Carry out,
1）, Uncinata Spikemoss Herb toothpaste annex solution preparation；
Include the component of following parts by weight：7.5-13 parts of Selaginella uncinata extraction, 12-18 parts of absolute ethyl alcohol, Natural menthol
8-12 parts, 8-12 parts of borneol, 20-29 parts of gaultherolin, 8-12 parts of first class spearmint oil, 3.5-8 parts of Thymol, caryophyllus oil
12-18 parts；Uniform mixing, the closed standing 20-30h in 20-30 DEG C of environment obtains Uncinata Spikemoss Herb toothpaste annex solution；
2）, mixture A preparation；
Include the component of following parts by weight：By 8-12 parts of Uncinata Spikemoss Herb toothpaste annex solution, 8-12 parts of deionized water, sorbierite
21-28 parts, 0.15-0.25 parts of saccharin sodium, 0.15-0.25 parts of tertiary sodium phosphate, 2-4 parts of calamitas urinae hominis stirs in 35-40 DEG C of environment
Uniformly, mixture A is obtained；
3）, mixture B preparation；
Include the component of following parts by weight：By 40-50 parts of calcium monohydrogen phosphate, 0.7-1.3 parts of sodium carboxymethylcellulose, laruyl alcohol
2-4 parts of sodium sulfovinate stirs, and obtains mixture B；
4）, foregoing obtained mixture A, mixture B inserted in container, add Mint Essence 0.7-1.3 parts by weight,
Uniform mixing；Sealing container, to container vacuum-pumping, vacuum -0.092MPa ~ 0.070MPa, temperature is kept in holding container
For 30-38 DEG C, agitating device is used in container, 30-35min stirring is maintained, the oral cavity containing Selaginella uncinata extraction is made
Cleansing cream.
It is including following heavy using application of the Selaginella uncinata extraction in mouth cleaning solution made from the preparation technology of the present invention
The component of part is measured,
60-70 parts of water, 8-12 parts of glycerine, 8-12 parts of sorbierite, 3-7 parts of rilanit special,
0.15-0.25 parts of sodium fluoride, 0.12-0.18 parts of sodium dihydrogen phosphate, 0.03-0.08 parts of disodium hydrogen phosphate, emerald green cloud
Careless extract 8-12 parts；
0.07-0.12 parts of menthanol lactic acid ester, 0.15-0.23 parts of essence；
Process according to the following steps：
1）, heat water to 55-65 DEG C, add glycerine, sorbierite and rilanit special, stirred under the conditions of 55-65 DEG C
Mix uniform, obtain mixture C；
2）, using phosphate adjust mixture C pH value to 7-8, then under the conditions of 55-65 DEG C add sodium fluoride, phosphoric acid
Disodium hydrogen, sodium dihydrogen phosphate and Selaginella uncinata extraction, stir to obtain mixture D；
3）, menthanol lactic acid ester and essence stirred at 15-30 DEG C, obtain mixture E；
4）, mixture D, mixture E uniformly mix, under the 50-90% of 1 standard atmospheric pressure pressure condition, keep constant temperature
40-45 DEG C, stir, the mouth cleaning solution containing Selaginella uncinata extraction is made.
The present invention carries out the pretreatment of mass to Uncinata Spikemoss Herb first, in pretreatment, and the state that employs consolidates-suspension conversion
Pattern, i.e., be suspension by powder immersion, in order to batch efficiently production, and phase is all used in each step changed more than
The control answered.Then operating type is extracted using efficient recoil；Recoil extract operation in, be effectively increased raw material with
Extract solution（Ethanol）Between contact area, the time, increase effect of extracting；Meanwhile, using ethanol to the phenols in Uncinata Spikemoss Herb, ketone
Class effectively carries out " dissolving, separation ", to greatest extent by the active ingredient in material after pretreatment, in specific technological parameter
Under the conditions of in the shortest time, to be extracted with highest efficiency.The oral-cavity cleaning products prepared using the present invention help to delay
Solve swelling and aching of gum, the situation of bleeding gums.
Brief description of the drawings
Fig. 1 is the structural representation of vertical vessel in the present invention,
1 is body in figure, and 2 be nozzle, and 3 be mouth spray, and 4 be Butterworth Hatch, and 5 be safety valve, and 6 be discharging opening, and 7 be bottom
Collecting bin.
Embodiment
The technical scheme is that：Process including being sorted to Uncinata Spikemoss Herb, dry, then carry out according to the following steps,
1）, crush；It is 300-450 mesh particles that the Uncinata Spikemoss Herb of the drying, which is crushed,；
2）, immersion；The particle is inserted in water and soaked 16-24 hours, the volume ratio of water and particle is 4-10:1；Obtain liquid
State mixture；
3）, heating；The liquefied mixture is heated up to 80-100 DEG C, kept for 1.5-2 hours；Obtain liquid mixed juice；
4）, concentration；By liquid mixed juice concentration, to the 10-30% that volume is the liquefied mixture；Obtain and slightly concentrate
Liquid；
5）, recoil extract；The thick concentrate is inserted to the top of vertical vessel, down sprayed；In the vertical vessel
Middle part and/or bottom and/or bottom the nozzles of opening upwards is set, by the nozzle to the top of the vertical vessel
Portion direction sprays the ethanol of aerosolization；
6）, collection bottom deposit pasty material, be cooled to 15-30 DEG C；
7）, be concentrated by evaporation；Ethanol in the pasty material is removed, sticky shape Selaginella uncinata extraction is obtained；
8）, finish.
As shown in figure 1, the vertical vessel includes cylindrical body 1, inside the body 1, from top to bottom provided with least
One circle top mouth spray 3, at least one circle bottom nozzle 2, bottom collection storehouse 7 and discharging opening 6.
Consider for safety and health, the safety valve 5 of Butterworth Hatch 4 can also be set at the top of body 1.
In the recoil abstraction process, pressure is 2-2.5 standard atmospheric pressure during work, and temperature is 60-75 DEG C.It is easy to phenol
The extraction of class, letones.
The emulsifying agent of 0.5-2 times of its quality is added in the Selaginella uncinata extraction, emulsification treatment is carried out.
The emulsifying agent is lecithin, sucrose fatty ester, olive oil, sorbitol anhydride monopalmitate, polyoxyethylene mountain
One kind or any two or more compoundings in pears alcohol acid anhydride monostearate.
Using the present invention preparation technology made from application of the Selaginella uncinata extraction in oral cleaning cream, according to the following steps
Carry out,
1）, Uncinata Spikemoss Herb toothpaste annex solution preparation；
Include the component of following parts by weight：7.5-13 parts of Selaginella uncinata extraction, 12-18 parts of absolute ethyl alcohol, Natural menthol
8-12 parts, 8-12 parts of borneol, 20-29 parts of gaultherolin, 8-12 parts of first class spearmint oil, 3.5-8 parts of Thymol, caryophyllus oil
12-18 parts；Uniform mixing, the closed standing 20-30h in 20-30 DEG C of environment obtains Uncinata Spikemoss Herb toothpaste annex solution；
2）, mixture A preparation；
Include the component of following parts by weight：By 8-12 parts of Uncinata Spikemoss Herb toothpaste annex solution, 8-12 parts of deionized water, sorbierite
21-28 parts, 0.15-0.25 parts of saccharin sodium, 0.15-0.25 parts of tertiary sodium phosphate, 2-4 parts of calamitas urinae hominis stirs in 35-40 DEG C of environment
Uniformly, mixture A is obtained；
3）, mixture B preparation；
Include the component of following parts by weight：By calcium monohydrogen phosphate（The mesh of fineness 600, percent of pass 99.8%）40-50 parts, carboxymethyl
0.7-1.3 parts of sodium cellulosate, 2-4 parts of laruyl alcohol sodium sulfovinate stir, and obtain mixture B；
4）, foregoing obtained mixture A, mixture B inserted in container, add Mint Essence 0.7-1.3 parts by weight,
Uniform mixing；Sealing container, to container vacuum-pumping, keeps vacuum -0.092MPa ~ 0.070MPa, temperature is 30-38 DEG C,
Agitating device is used in container, 30-35min stirring is maintained, the oral cleaning cream containing Selaginella uncinata extraction is made.Take out true
Sky, makes that finished surface is smooth, uniform, exquisiteness, while ensureing to combine even closer between each component, it is to avoid free.
It is including following heavy using application of the Selaginella uncinata extraction in mouth cleaning solution made from the preparation technology of the present invention
The component of part is measured,
60-70 parts of water, 8-12 parts of glycerine, 8-12 parts of sorbierite, 3-7 parts of rilanit special,
0.15-0.25 parts of sodium fluoride, 0.12-0.18 parts of sodium dihydrogen phosphate, 0.03-0.08 parts of disodium hydrogen phosphate, emerald green cloud
Careless extract 8-12 parts；
0.07-0.12 parts of menthanol lactic acid ester, 0.15-0.23 parts of essence；
Process according to the following steps：
1）, heat water to 55-65 DEG C, add glycerine, sorbierite and rilanit special, stirred under the conditions of 55-65 DEG C
Mix uniform, obtain mixture C；
2）, using phosphate adjust the pH value of mixture C to 7-8（Determined with the extensive test paper of PH）, then in 55-65 DEG C of condition
Lower addition sodium fluoride, disodium hydrogen phosphate, sodium dihydrogen phosphate and Selaginella uncinata extraction, stir to obtain mixture D；
3）, menthanol lactic acid ester and essence stirred at 15-30 DEG C, obtain mixture E；
4）, mixture D, mixture E uniformly mix, under the 50-90% of 1 standard atmospheric pressure pressure condition, keep constant temperature
40-45 DEG C, stir, the mouth cleaning solution containing Selaginella uncinata extraction is made.Under this pressure condition, wherein grease state material
Can more uniformly " scattered " in the product.
Specifically the present invention is described further below by embodiment, the rights protection scope of patent of the present invention includes
But it is not limited to this.
Embodiment one
It is 300 mesh particles that Uncinata Spikemoss Herb, which is crushed,；Measure 1 liter；Insert in water and soak 16 hours, water takes 4 liters；Obtain liquid mixing
Thing；80 DEG C are heated up to immediately, are kept for 2 hours；Obtain liquid mixed juice；
Liquid mixed juice is concentrated, to 1.5 liters of volume；Obtain thick concentrate；
Recoil is extracted；Thick concentrate is inserted to the top of vertical vessel, down sprayed；At the middle part and bottom of vertical vessel
The nozzle of opening upwards is set, the ethanol of aerosolization is sprayed to the top-direction of vertical vessel by nozzle；Recoil is extracted
In process, pressure is 2.5 standard atmospheric pressures during work, and temperature is 75 DEG C.Because the phenols in material, ketones component are less soluble
Yu Shui, ethanol serves " solvent " in operation is extracted in foregoing recoil.
The pasty material of bottom deposit is gathered, 30 DEG C are cooled to；
It is concentrated by evaporation；Ethanol in pasty material is removed, sticky shape Selaginella uncinata extraction is obtained；It should be noted that mistake herein
Evaporating temperature can be properly increased in journey, water content is reduced.But phenols, ketones component now in material can retain in grease state
In sticky shape Selaginella uncinata extraction after evaporation.
Obtained sticky shape Selaginella uncinata extraction contains the phenols and letones of grease state, is more preferable progress next step
Application, emulsification processing can be carried out to it.Enable to the phenols and letones of grease state evenly scattered.
Embodiment two
It is 450 mesh particles that Uncinata Spikemoss Herb, which is crushed,；Measure 1 liter；Insert in water and soak 24 hours, water takes 10 liters；Liquid is obtained to mix
Compound；100 DEG C are heated up to immediately, are kept for 1.5 hours；Obtain liquid mixed juice；
Liquid mixed juice is concentrated, to 1.1 liters of volume；Obtain thick concentrate；
Recoil is extracted；Thick concentrate is inserted to the top of vertical vessel, down sprayed；At the middle part and bottom of vertical vessel
The nozzle of opening upwards is set, the ethanol of aerosolization is sprayed to the top-direction of vertical vessel by nozzle；Recoil is extracted
In process, pressure is 2 standard atmospheric pressures during work, and temperature is 60 DEG C.
The pasty material of bottom deposit is gathered, 15 DEG C are cooled to；
It is concentrated by evaporation；Ethanol in pasty material is removed, sticky shape Selaginella uncinata extraction is obtained；It should be noted that mistake herein
Evaporating temperature can be properly increased in journey, water content is reduced.But phenols, ketones component now in material can retain in grease state
In sticky shape Selaginella uncinata extraction after evaporation.
Obtained sticky shape Selaginella uncinata extraction contains the phenols and letones of grease state, is more preferable progress next step
Application, emulsification processing can be carried out to it.Enable to the phenols and letones of grease state evenly scattered.
Embodiment three
It is 370 mesh particles that Uncinata Spikemoss Herb, which is crushed,；Measure 1 liter；Insert in water and soak 20 hours, water takes 8 liters；Obtain liquid mixing
Thing；90 DEG C are heated up to immediately, are kept for 1.8 hours；Obtain liquid mixed juice；
Liquid mixed juice is concentrated, to 2.7 liters of volume；Obtain thick concentrate；
Recoil is extracted；Thick concentrate is inserted to the top of vertical vessel, down sprayed；At the middle part and bottom of vertical vessel
The nozzle of opening upwards is set, the ethanol of aerosolization is sprayed to the top-direction of vertical vessel by nozzle；Recoil is extracted
In process, pressure is 2.2 standard atmospheric pressures during work, and temperature is 70 DEG C.
The pasty material of bottom deposit is gathered, 20 DEG C are cooled to；
It is concentrated by evaporation；Ethanol in pasty material is removed, sticky shape Selaginella uncinata extraction is obtained.
Claims (8)
1. a kind of preparation technology of Selaginella uncinata extraction, including the process for sorting, drying to Uncinata Spikemoss Herb, it is characterised in that press again
Following steps are carried out,
1）, crush；It is 300-450 mesh particles that the Uncinata Spikemoss Herb of the drying, which is crushed,；
2）, immersion；The particle is inserted in water and soaked 16-24 hours, the volume ratio of water and particle is 4-10:1；Liquid is obtained to mix
Compound；
3）, heating；The liquefied mixture is heated up to 80-100 DEG C, kept for 1.5-2 hours；Obtain liquid mixed juice；
4）, concentration；By liquid mixed juice concentration, to the 10-30% that volume is the liquefied mixture；Obtain thick concentrate；
5）, recoil extract；The thick concentrate is inserted to the top of vertical vessel, down sprayed；In the vertical vessel
Portion and/or bottom and/or bottom set the nozzle of opening upwards, by the nozzle to the top side of the vertical vessel
To the ethanol for spraying aerosolization；
6）, collection bottom deposit pasty material, be cooled to 15-30 DEG C；
7）, be concentrated by evaporation；Ethanol in the pasty material is removed, sticky shape Selaginella uncinata extraction is obtained, evaporating temperature is improved, obtains
Phenols, ketones component are in the Selaginella uncinata extraction of grease state；
8）, finish.
2. a kind of preparation technology of Selaginella uncinata extraction according to claim 1, it is characterised in that the vertical vessel bag
Include cylindrical body, in the body interior, from top to bottom provided with least one circle top mouth spray, at least one circle bottom nozzle,
Bottom collection storehouse and discharging opening.
3. the preparation technology of a kind of Selaginella uncinata extraction according to claim 2, it is characterised in that in the vertical vessel
Top be additionally provided with safety valve and rinse mouth.
4. the preparation technology of a kind of Selaginella uncinata extraction according to claim 1, it is characterised in that work is extracted in the recoil
In sequence, pressure is 2-2.5 standard atmospheric pressure during work, and temperature is 60-75 DEG C.
5. the preparation technology of a kind of Selaginella uncinata extraction according to claim 1, it is characterised in that carried in the Uncinata Spikemoss Herb
The emulsifying agent that 0.5-2 times of its quality is added in thing is taken, emulsification treatment is carried out.
6. the preparation technology of a kind of Selaginella uncinata extraction according to claim 5, it is characterised in that the emulsifying agent is ovum
One in phosphatide, sucrose fatty ester, olive oil, sorbitol anhydride monopalmitate, polyoxyethylene sorbitan monostearate
Plant or any two or more compoundings.
7. Selaginella uncinata extraction made from a kind of a kind of preparation technology of Selaginella uncinata extraction described in claim 1 is clear in oral cavity
Application in clean cream, it is characterised in that carry out according to the following steps,
1）, Uncinata Spikemoss Herb toothpaste annex solution preparation；
Include the component of following parts by weight：7.5-13 parts of Selaginella uncinata extraction, 12-18 parts of absolute ethyl alcohol, Natural menthol 8-12
Part, 8-12 parts of borneol, 20-29 parts of gaultherolin, 8-12 parts of first class spearmint oil, 3.5-8 parts of Thymol, caryophyllus oil 12-
18 parts；Uniform mixing, the closed standing 20-30h in 20-30 DEG C of environment obtains Uncinata Spikemoss Herb toothpaste annex solution；
2）, mixture A preparation；
Include the component of following parts by weight：By 8-12 parts of Uncinata Spikemoss Herb toothpaste annex solution, 8-12 parts of deionized water, sorbierite 21-28
Part, 0.15-0.25 parts of saccharin sodium, 0.15-0.25 parts of tertiary sodium phosphate, 2-4 parts of calamitas urinae hominis stirs in 35-40 DEG C of environment,
Obtain mixture A；
3）, mixture B preparation；
Include the component of following parts by weight：By 40-50 parts of calcium monohydrogen phosphate, 0.7-1.3 parts of sodium carboxymethylcellulose, laruyl alcohol sulfuric acid
2-4 parts of ester sodium stirs, and obtains mixture B；
4）, foregoing obtained mixture A, mixture B inserted in container, add Mint Essence 0.7-1.3 parts by weight, uniformly
Mixing；Sealing container, to container vacuum-pumping, vacuum -0.092MPa ~ 0.070MPa in holding container, temperature is 30-38
DEG C, agitating device is used in container, 30-35min stirring is maintained, the oral cleaning cream containing Selaginella uncinata extraction is made.
8. Selaginella uncinata extraction made from a kind of a kind of preparation technology of Selaginella uncinata extraction described in claim 1 is clear in oral cavity
Application in clean liquid, it is characterised in that include the component of following parts by weight,
60-70 parts of water, 8-12 parts of glycerine, 8-12 parts of sorbierite, 3-7 parts of rilanit special,
0.15-0.25 parts of sodium fluoride, 0.12-0.18 parts of sodium dihydrogen phosphate, 0.03-0.08 parts of disodium hydrogen phosphate, Uncinata Spikemoss Herb is carried
Take 8-12 parts of thing；
0.07-0.12 parts of menthanol lactic acid ester, 0.15-0.23 parts of essence；
Process according to the following steps：
1）, heat water to 55-65 DEG C, add glycerine, sorbierite and rilanit special, stir equal under the conditions of 55-65 DEG C
It is even, obtain mixture C；
2）, using phosphate adjust mixture C pH value to 7-8, then under the conditions of 55-65 DEG C add sodium fluoride, phosphoric acid hydrogen two
Sodium, sodium dihydrogen phosphate and Selaginella uncinata extraction, stir to obtain mixture D；
3）, menthanol lactic acid ester and essence stirred at 15-30 DEG C, obtain mixture E；
4）, mixture D, mixture E uniformly mix, under the 50-90% of 1 standard atmospheric pressure pressure condition, keep constant temperature 40-
45 DEG C, stir, the mouth cleaning solution containing Selaginella uncinata extraction is made.
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| CN101357144A (en) * | 2008-09-17 | 2009-02-04 | 暨南大学 | Selaginella uncinata extraction, its preparation method and application |
| CN102579305A (en) * | 2012-03-29 | 2012-07-18 | 安徽两面针·芳草日化有限公司 | Natural medicine toothpaste with saussurea involucrata as major material |
| CN102772912A (en) * | 2012-07-05 | 2012-11-14 | 西安鸿生生物技术有限公司 | Device and method for extracting effective components from natural plant by high-pressure spraying reverse-flow process |
| CN103520010A (en) * | 2013-10-18 | 2014-01-22 | 柳州两面针股份有限公司 | Application of tetrahydropalmatine and naringin in preparing oral care products |
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| CN101357144A (en) * | 2008-09-17 | 2009-02-04 | 暨南大学 | Selaginella uncinata extraction, its preparation method and application |
| CN102579305A (en) * | 2012-03-29 | 2012-07-18 | 安徽两面针·芳草日化有限公司 | Natural medicine toothpaste with saussurea involucrata as major material |
| CN102772912A (en) * | 2012-07-05 | 2012-11-14 | 西安鸿生生物技术有限公司 | Device and method for extracting effective components from natural plant by high-pressure spraying reverse-flow process |
| CN103520010A (en) * | 2013-10-18 | 2014-01-22 | 柳州两面针股份有限公司 | Application of tetrahydropalmatine and naringin in preparing oral care products |
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