CN1044860C

CN1044860C - Rheumatism medicine

Info

Publication number: CN1044860C
Application number: CN93111928A
Authority: CN
Inventors: 赖玉良
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-08-09
Filing date: 1993-08-09
Publication date: 1999-09-01
Anticipated expiration: 2013-08-09
Also published as: CN1098643A

Abstract

The present invention provides a novel externally-applied liniment for treating rheumatism. Every 100 ml of liniment is prepared from 7 to 12 g go camphore, 0.8 to 2.2g of menthol, 0.2 to 0.7g of thyme oil, 1 to 5 ml of phenylmethanol, 40 to 60 ml of turpentine, and vegetable oil as the rest. The effective components and the auxiliary agents are dissolved and mixed with a known method to prepare the liniment. The liniment is especially used for treating rheumatism, rheumatoid arthritis, etc., and has the effects of fast alleviating pain and eliminating swelling.

Description

The rheumatism liniment

The present invention relates to the medical supplies technical field.

Arthritis is one of common disease that is detrimental to health, particularly rheumatoid arthritis, and home and overseas all has a lot of people inquiring into its cause of disease, seeks the situation that effectively prevention and Therapeutic Method change its prognosis mala.Rheumatoid arthritis is a kind of cause of disease arthritis of not sure chronic progressive external as yet so far, it has been generally acknowledged that it is a kind of autoimmunity illness, be the result that body defending system is killed each other and caused, heredity in addition, infection, zero cold humidity etc. all may be morbific factors.Arthritic mainly is synovial membrane inflammation in early days, synovial membrane hyperemia, swelling, has fibrin to ooze out, and forms hydrarthrosis, and typical inflammatory cell infiltration is arranged in the synovial membrane, involves articular cartilage and osseous tissue then, finally causes ankylosis.That ill joint shows as is red, swollen, hot, pain and moving obstacle, and joint deformity is more and more obvious, and patient's rheumatoid factor is often positive, and the X ray examination has significantly unusual performance.Doctor trained in Western medicine mainly is an oral drug therapy to treatment of rheumatoid arthritis, and salicylic acid formulation example such as aspirin are drug of first choice, is indometacin secondly, and Phenylbutazone and prednisone etc. are to the feasible operative treatment of end-stage patients.Rheumatoid arthritis belongs to " arthromyodynia " scope in motherland's medical science, with the dampness removing collateral dredging, dispelling cold by warming the meridian is main, prescription commonly used is thought for the Radix Angelicae Pubescentis et Herba Taxilli Decoction theory of Chinese medical science, and the rheumatoid origin cause of formation is mostly because the wet outer ailment said due to cold or exposure of invading, feel again of water, or the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, it is wet to hold under the arm to hold concurrently, so that invasion of the body by blended pathogenic wind and dampness and falling ill, linger on as rheumatism and not go, arthralgia can take place, articular instability, or grain contracture, or disease such as apathy, and often with the passing of time delay forms chronic disease.In sum, diseases such as rheumatism, rheumatoid arthritis still do not have specific short in treatment, and existing Drug therapy mainly is all kinds of medicinal preparation for oral administration, need just can cure the disease after intestinal absorption, can not directly alleviate arthralgia and inflammation.In addition, also available Camphora, Mentholum and the terebinthine ZHENGHONGHUA YOU (very imperial board, Radix Achyranthis Bidentatae pharmaceutcal corporation, Ltd in Hong Kong produce) of containing be as liniment, but curative effect is unreliable during diseases such as this ZHENGHONGHUA YOU treatment rheumatism and rheumatoid arthritis, it is low to cure obvious effective rate, is 45%; Effective percentage is low, is 78.3%, and alleviating pain and detumescence onset time is long.

The purpose of this invention is to provide the wind dispelling analgesia, be specifically designed to the external liniment of diseases such as rheumatism, rheumatoid arthritis, have quickly alleviating pain repercussive effect.

Rheumatism liniment of the present invention, the proportioning of its active ingredient and adjuvant is: every 100ml contains Camphora 7-12g, Mentholum 0.8-2.2g, Oleum thymi vulgaris 0.2-0.7g, benzyl alcohol 1-5ml, Oleum Terebinthinae 40-60ml, surplus is that Oleum Gossypii semen adds to 100ml, makes liniment with known method.

Rheumatism liniment of the present invention, its active ingredient and adjuvant proportioning preferably are: every 100ml contains Camphora 8-11g, Mentholum 1.5-2.1g, Oleum thymi vulgaris 0.3-0.6g, benzyl alcohol 2-4ml, Oleum Terebinthinae 45-55ml, surplus is that Oleum Gossypii semen adds to 100ml.

Rheumatism liniment of the present invention, the better proportioning of its active ingredient and adjuvant are that every 100ml contains Camphora 9.5-10g, Mentholum 1.9-2g, and Oleum thymi vulgaris 0.4-0.5g, benzyl alcohol 2.5-3ml, Oleum Terebinthinae 48-50ml, surplus is that Oleum Gossypii semen adds to 100ml.

Rheumatism liniment of the present invention, the best proportioning of its active ingredient and adjuvant is: every 100ml contains Camphora 10g, Mentholum 2g, Oleum thymi vulgaris 0.5g, benzyl alcohol 3ml, Oleum Terebinthinae 50ml, surplus is that Oleum Gossypii semen adds to 100ml.

The method for making of rheumatism liniment of the present invention is as follows, getting Oleum Terebinthinae puts in the rustless steel container, adding the dissolving of Camphora, Mentholum successively stirs evenly, add benzyl alcohol, Oleum thymi vulgaris, Oleum Gossypii semen mixing then successively, stir evenly with blender, leave standstill 24 hours after-filtration, detection, with the filling machine bottling, the storehouse is entered in packing.

The advantage of rheumatism liniment of the present invention is: it is a kind of externally-applied liniment for (1), rheumatism, rheumatoid arthritis etc. had quickly alleviating pain repercussive effect, help rapid control, alleviating pain and inflammation, the confidence and the courage that patient are strengthened struggle with disease.(2) it for scapulohumeral periarthritis severe pain, sprain and get injured by a fall pain, paralysis sick convalescent period and take exercise and be afraid of that pain etc. also has tangible curative effect.(3) it also has effects such as antipruritic detoxification, refreshment concurrently.

Content in the specific embodiment of rheumatism liniment of the present invention among the every 100ml of the proportioning of its active ingredient and adjuvant is as shown in the table.

Each component title	Example 1	Example 2	Example 3	Example 4	Example 5	Example 6
Each component title	Example 1	Example 2	Example 3	Example 4	Example 5	Example 6	Camphora (g/100ml)	7	8	9	11	12	10
Mentholum (g/100ml)	2.2	2.1	1.9	1.5	0.8	2	Camphora (g/100ml)	7	8	9	11	12	10
Mentholum (g/100ml)	2.2	2.1	1.9	1.5	0.8	2	Oleum thymi vulgaris (ml/100ml)	0.7	0.6	0.4	0.3	0.2	0.5
Benzyl alcohol (ml/100ml)	5	4	2.5	2	1	3	Oleum thymi vulgaris (ml/100ml)	0.7	0.6	0.4	0.3	0.2	0.5
Benzyl alcohol (ml/100ml)	5	4	2.5	2	1	3	Oleum Terebinthinae (ml/100ml)	60	55	48	45	40	50
Oleum Gossypii semen ml/100ml)	Surplus is that Oleum Gossypii semen adds to 100ml						Oleum Terebinthinae (ml/100ml)	60	55	48	45	40	50

Camphora is white crystalline powder or colourless translucent lump, has that the zest spy is smelly, flavor is just hot, the back is refrigerant, is soluble in Oleum Terebinthinae (1: 1.5) and is local irritant, and central stimulant has antipruritic, analgesia, effect such as antibiotic.Mentholum is colourless needle-like or prismatic crystallization or white crystalline powder or frit, and the pungent odor of similar Herba Menthae is arranged, and flavor is just scorching hot, and the back is refrigerant, can mix arbitrarily with Oleum Terebinthinae, have anticorrosion, refrigerant, antipruritic, draw effects such as red.Benzyl alcohol is a colorless and odorless liquid, severe pungent is arranged, local anesthesia and antisepsis Oleum thymi vulgaris another name Caulis et folium gaultheriae yunnanensis oil is arranged, it is a kind of quintessence oil that the Caulis et folium gaultheriae yunnanensis herb is made through distillation, mainly containing farnesol and fragrant non-irrigated seed oil phenol and pinene, terpineol, geraniol etc., to brown liquid, is a kind of aromatic for colourless, have strong sterilizing power, and anthelmintic, effect such as antipruritic, anticorrosion are arranged.Oleum Gossypii semen is faint yellow or yellow clear liquid, and odorless or odorless, lightly seasoned almost are excipient, lubricant, and as the substrate of liniment, its can guarantee effect by long-term control stable content, and injured skin is not had any zest and anaphylaxis.The effect of above medicine sees also Shandong science tech publishing house and publishes " department of dermatologry medicine for external use handbook in April, 1981 front page, book number 14195.53, the Shaanxi People's Press publishes " dermatosis prescription, Arzneibucs ", in JIUYUE, 1977 front page, book number 14094.29.Advantages such as simultaneously, it is reliable that this rheumatism liniment has curative effect, and produce effects is quick.

The manufacture method of rheumatism liniment of the present invention is, adopts known method to make liniment according to the proportioning of active ingredient in the various embodiments described above and adjuvant.At first get Oleum Terebinthinae and place rustless steel container, add the dissolving of Camphora, Mentholum successively and stir evenly, add benzyl alcohol, Oleum thymi vulgaris, Oleum Gossypii semen at last successively and mix, stir evenly with blender, leave standstill 24 hours after-filtration, detection, with the filling machine bottling, the storehouse is entered in packing.Its using method is, every day 2-3 time, bottle point place oozes to be coated with puts on the skin, and slightly firmly hot skin is put in massage on the skin, just can reach the quickly alleviating pain effect, and this product is that externally-applied liniment must not take orally.

Claims

1, the rheumatismal liniment of a kind of treatment, include Camphora, Mentholum, Oleum Terebinthinae, it is characterized in that being made up of the active ingredient and the adjuvant of following proportioning: every 100ml contains Camphora 7-12g, Mentholum 0.8-2.2g, Oleum thymi vulgaris 0.2-0.7g, benzyl alcohol 1-5ml, Oleum Terebinthinae 40-60ml, surplus is that Oleum Gossypii semen adds to 100ml, makes liniment with known method.

2, the rheumatismal liniment of treatment according to claim 1, it is characterized in that active ingredient and adjuvant preferably proportioning be: every 100ml contains Camphora 8-11g, Mentholum 1.5-2.1g, Oleum thymi vulgaris 0.3-0.6g, benzyl alcohol 2-4ml, Oleum Terebinthinae 45-55ml, surplus is that Oleum Gossypii semen adds to 100ml.

3, the rheumatismal liniment of treatment according to claim 1 and 2, it is characterized in that the better proportioning of active ingredient and adjuvant is: every 100ml contains Camphora 9.6-10g, Mentholum 1.9-2g, Oleum thymi vulgaris 0.4-0.5g, benzyl alcohol 2.5-3ml, Oleum Terebinthinae 48-50ml, surplus is that Oleum Gossypii semen adds to 100ml.

4, the rheumatismal liniment of treatment according to claim 3, it is characterized in that the best proportioning of active ingredient and adjuvant is: every 100ml contains Camphora 10g, Mentholum 2g, Oleum thymi vulgaris 0.5g, benzyl alcohol 3ml, Oleum Terebinthinae 50ml, surplus is that Oleum Gossypii semen adds to 100ml.