CN105125704B - A kind of compositions purposes in the medicine of preparation treatment gout - Google Patents
A kind of compositions purposes in the medicine of preparation treatment gout Download PDFInfo
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- CN105125704B CN105125704B CN201510585103.3A CN201510585103A CN105125704B CN 105125704 B CN105125704 B CN 105125704B CN 201510585103 A CN201510585103 A CN 201510585103A CN 105125704 B CN105125704 B CN 105125704B
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Abstract
The present invention relates to a kind of pharmaceutical composition treating gout, it is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, Herba asplenii trichomanis 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30 parts, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle steep 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts and 10 parts of Radix Glycyrrhizae.The pharmaceutical composition for the treatment of gout of the present invention uses natural drug, and therefore it has instant effect, good effect, the advantage that has no side effect.
Description
The present invention is the divisional application of the patent of Application No. 201510195261.8, filing date on April 23rd, 2015, invention entitled " a kind of pharmaceutical composition treating gout ".
Technical field
The present invention relates to field of medicaments, specifically, relate to a kind of pharmaceutical composition treating gout.
Background technology
Gout is that urate crystal deposits the pathological changes caused, and can involve foot, the most often involve Metatarsophalangeal joint, cause acute inflammatory reaction synovitis.Gout is that purine metabolic disturbance causes uric acid to synthesize the metabolic disease increased and cause.Also uric acid level can be caused to rise owing to the uric acid clearance of kidney declines during renal dysfunction.Uric acid in blood plasma reaches saturated, causes monosodium urate crystallization deposition relative in the tissue lacking blood vessel around distal joint.The appearance of this crystallization may result in simple joint or multiarticulate acute inflammation synovitis.Gout is the most common in male, and big toe is modal affected area, and 50%～70% first attack betides this.The patient with gout of 90% can occur Metatarsophalangeal joint to get involved in its certain period in life.Other foot area that may get involved have dorsal portion, heel and ankle.In addition to involving joint, uric acid crystal can also be deposited on subcutaneous, is referred to as tophus.Show as the serious pain of affected joints, swelling, erythema, stiff, heating, and symptom during gouty attack,acute to occur suddenly.Stage of attack general last from days to 1 week.Inducement is not had during general morbidity, but after mild trauma can being secondary to or eating rich in the food of purine.
Summary of the invention
It is an object of the invention to provide a kind of pharmaceutical composition treating gout.
In order to realize the purpose of the present invention, the present invention provides a kind of pharmaceutical composition treating gout, and it is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, Herba asplenii trichomanis 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30 parts, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle steep 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts and 10 parts of Radix Glycyrrhizae.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, ointment or suppository.
The present invention also provides for compositions purposes in the medicine of preparation treatment gout, and described medicine is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, Herba asplenii trichomanis 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30 parts, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle steep 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts and 10 parts of Radix Glycyrrhizae.
In the present compositions, beautiful hieracioides is monarch drug, and Herba asplenii trichomanis, RADIX DIPLOCCISIAE, Herba speranskiae tuberculatae are ministerial drug, and pilea mongolica, Cortex Meliosmatis rigidae Radicis, Herba Ainsliaeae Latifoliae, Herba tiarellae polyphyllae, Cor Cervi grass, triangle bubble, Tinomiscium petiolare Hook. f. et Thoms are adjuvant drug, and Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.
Using natural drug in the medicine for the treatment of gout of the present invention, therefore it has instant effect, good effect, the advantage that has no side effect.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to the basic thought of the present invention, various modifications may be made or improves, but without departing from the basic thought of the present invention, the most within the scope of the present invention.
The preparation of embodiment ointment of the present invention
Weigh beautiful hieracioides 500 grams, Herba asplenii trichomanis 500 grams, RADIX DIPLOCCISIAE 400 grams, Herba speranskiae tuberculatae 450 grams, pilea mongolica 400 grams, Cortex Meliosmatis rigidae Radicis 300 grams, Herba Ainsliaeae Latifoliae 350 grams, Herba tiarellae polyphyllae 300 grams, Cor Cervi grass 300 grams, triangle bubble 300 grams, Tinomiscium petiolare Hook. f. et Thoms 200 grams and 100 grams of Radix Glycyrrhizae, pulverize, cross 100 mesh sieves, it is subsequently adding lanoline 300 grams and 200 grams of vaseline, stirs and get final product.
Experimental example
Diagnostic criteria
Reference " internal medicine " (Chen Haozhu. practical internal medicine [M]. the 13rd edition. Beijing: People's Health Publisher, 2009.2364-2370.)) formulate diagnostic criteria, disease see occur suddenly big toe, open up toe, stamp, knee joint etc. simple joint red and swollen heat pain, or urate increases, Effects of Colchicine In Treating has specially good effect, synovial bursa fluid inspection to find urate crystal.
Choose patient 200 example meeting above-mentioned standard, the maleest 100 examples, female 100 example；Age 39～63 years old, average 46 years old.
Use the ointment prepared in embodiment to treat, three times a day, use 10 grams of ointments to be coated uniformly on the affected part of swelling pain, treatment 7 days continuously every time.
Criterion of therapeutical effect
Reference " Chinese medical disease Standardization of diagnosis and curative effect " (State Administration of Traditional Chinese Medicine. Chinese medical disease Standardization of diagnosis and curative effect [M]. Nanjing: publishing house of Nanjing University, 1994.50-51.) formulate.Cure: arthralgia, swelling disappear, and blood uric acid is normal, without recurrence in March.Taking a turn for the better: arthralgia, swelling alleviate, have recurrence but treat and remain to alleviate in March, blood uric acid declines.Invalid: arthralgia, swelling etc. are without significant change, and blood uric acid is unchanged.
Result
Through treatment, finding that the arthralgia of all patients, swelling disappear, blood routine examination blood uric acid is within normal range, and follows up a case by regular visits to 3 months without recurrence.Do not find obvious untoward reaction over the course for the treatment of.
Model case
Wang, man, 45 years old, suffer from gout for many years, due to work relationship, often treat with courtesy, the tall and big obesity of build, blood uric acid, lipids contents all beyond normal range, two foot big toes, knee joint frequent repeatability congestion and swelling pain, when taking medicine, symptom slightly takes a turn for the better, through the most repeatedly after drug withdrawal, the ointment prepared in embodiment is used to treat, three times a day, use 10 grams of ointments to be coated uniformly on the affected part of swelling pain, treatment 7 days continuously every time.The arthralgia of patient, swelling disappear, and blood routine examination blood uric acid is within normal range, and follows up a case by regular visits to 3 months without recurrence.
Claims (1)
1. compositions purposes in the medicine of preparation treatment gout, it is characterised in that described
Medicine is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, ferrum angle phoenix tail
Grass 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30
Part, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle bubble 30 parts, great Ye
20 parts of rattan and 10 parts of Radix Glycyrrhizae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510585103.3A CN105125704B (en) | 2015-04-23 | 2015-04-23 | A kind of compositions purposes in the medicine of preparation treatment gout |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510195261.8A CN104740029B (en) | 2015-04-23 | 2015-04-23 | A kind of pharmaceutical composition for the treatment of gout |
| CN201510585103.3A CN105125704B (en) | 2015-04-23 | 2015-04-23 | A kind of compositions purposes in the medicine of preparation treatment gout |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510195261.8A Division CN104740029B (en) | 2015-04-23 | 2015-04-23 | A kind of pharmaceutical composition for the treatment of gout |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105125704A CN105125704A (en) | 2015-12-09 |
| CN105125704B true CN105125704B (en) | 2016-09-28 |
Family
ID=53580651
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510585103.3A Expired - Fee Related CN105125704B (en) | 2015-04-23 | 2015-04-23 | A kind of compositions purposes in the medicine of preparation treatment gout |
| CN201510195261.8A Expired - Fee Related CN104740029B (en) | 2015-04-23 | 2015-04-23 | A kind of pharmaceutical composition for the treatment of gout |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510195261.8A Expired - Fee Related CN104740029B (en) | 2015-04-23 | 2015-04-23 | A kind of pharmaceutical composition for the treatment of gout |
Country Status (1)
| Country | Link |
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| CN (2) | CN105125704B (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732498A (en) * | 2008-11-17 | 2010-06-16 | 任风辉 | Formula of Chinese medicament for treating gout |
| CN102793878B (en) * | 2012-09-03 | 2016-01-13 | 吴鎏桢 | A kind of gout fast analgesic paste |
| CN105055558A (en) * | 2014-02-08 | 2015-11-18 | 刘向荣 | Traditional Chinese medicine combination for treating gout |
| CN104147377A (en) * | 2014-09-04 | 2014-11-19 | 张湘君 | Traditional Chinese medicinal preparation for treating gout disease |
-
2015
- 2015-04-23 CN CN201510585103.3A patent/CN105125704B/en not_active Expired - Fee Related
- 2015-04-23 CN CN201510195261.8A patent/CN104740029B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN104740029B (en) | 2015-12-09 |
| CN105125704A (en) | 2015-12-09 |
| CN104740029A (en) | 2015-07-01 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Lin Inventor after: Tian Chunmei Inventor after: Chen Liang Inventor before: Wang Ailing |
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| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160817 Address after: 661 Department of Radiology, Affiliated Hospital of Binzhou Medical College, two the Yellow River Road, Bincheng District, Shandong, Binzhou 256603, China Applicant after: Zhang Lin Address before: 054000, No. 9, middle street, Luo Luo Road, Xingtai County, Xingtai, Hebei Applicant before: Wang Ailing |
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Granted publication date: 20160928 Termination date: 20170423 |
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| CF01 | Termination of patent right due to non-payment of annual fee |