CN104740029A - Pharmaceutical composition for treating gout - Google Patents
Pharmaceutical composition for treating gout Download PDFInfo
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- CN104740029A CN104740029A CN201510195261.8A CN201510195261A CN104740029A CN 104740029 A CN104740029 A CN 104740029A CN 201510195261 A CN201510195261 A CN 201510195261A CN 104740029 A CN104740029 A CN 104740029A
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Abstract
The invention relates to a pharmaceutical composition for treating gout. The pharmaceutical composition is prepared by the following active ingredients in parts by weight: 50 parts of saussurea pulchra, 50 parts of maidenhair spleenwort, 40 parts of diploclisia affinis, 45 parts of garden balsam stem, 40 parts of pilea pumila, 30 parts of meliosma rigida, 35 parts of ainsliaea latifolia, 30 parts of tiarella polyphylla, 30 parts of herba pyrolae, 30 parts of cardiospermum halicacabum, 20 parts of tinomiscium and 10 parts of liquorice. The pharmaceutical composition for treating the gout utilizes natural herbs and has advantages of quick result, good curative effect, non-toxicity and no side effect.
Description
Technical field
The present invention relates to field of medicaments, specifically, relate to a kind of pharmaceutical composition for the treatment of gout.
Background technology
Gout is that urate crystal deposits the pathological changes caused, and can involve foot, the most often involve Metatarsophalangeal joint, cause acute inflammatory reaction synovitis.Gout is that purine metabolic disturbance causes uric acid to synthesize to increase and the metabolic disease that causes.Also uric acid level can be caused to rise because the uric acid clearance of kidney declines during renal dysfunction.Uric acid in blood plasma reaches capacity, and causes monosodium urate crystallization deposition relatively to lack in the tissue of blood vessel around distal joint.The appearance of this crystallization can cause simple joint or multiarticulate acute inflammation synovitis.Gout is comparatively common in male, and big toe is modal affected area, and 50% ~ 70% first attack betides this.Metatarsophalangeal joint can be there is and get involved in the patient with gout of 90% in its certain period in life.Other foot area that may get involved have dorsal portion, heel and ankle.Except involving joint, uric acid crystal can also be deposited on subcutaneous, is referred to as tophus.Show as the serious pain of affected joints, swelling, erythema, stiff, heating during gouty attack,acute, and symptom occurs suddenly.Stage of attack, general last from days was by 1 week.There is no inducement during general morbidity, but can be secondary to mild trauma or edible be rich in the food of purine after.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition for the treatment of gout.
In order to realize object of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of gout, it is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, Herba asplenii trichomanis 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30 parts, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle steep 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts and 10 parts, Radix Glycyrrhizae.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, ointment or suppository.
The present invention also provides the purposes of compositions in the medicine of preparation treatment gout, and described medicine is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, Herba asplenii trichomanis 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30 parts, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle steep 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts and 10 parts, Radix Glycyrrhizae.
In the present compositions, beautiful hieracioides is monarch drug, and Herba asplenii trichomanis, RADIX DIPLOCCISIAE, Herba speranskiae tuberculatae are ministerial drug, and pilea mongolica, Cortex Meliosmatis rigidae Radicis, Herba Ainsliaeae Latifoliae, Herba tiarellae polyphyllae, Cor Cervi grass, triangle bubble, Tinomiscium petiolare Hook. f. et Thoms are adjuvant drug, and Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.
Use natural drug in the medicine for the treatment of gout of the present invention, therefore it has instant effect, good effect, the advantage that has no side effect.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment ointment of the present invention
Take beautiful hieracioides 500 grams, Herba asplenii trichomanis 500 grams, RADIX DIPLOCCISIAE 400 grams, Herba speranskiae tuberculatae 450 grams, pilea mongolica 400 grams, Cortex Meliosmatis rigidae Radicis 300 grams, Herba Ainsliaeae Latifoliae 350 grams, Herba tiarellae polyphyllae 300 grams, Cor Cervi grass 300 grams, triangle steep 300 grams, Tinomiscium petiolare Hook. f. et Thoms 200 grams and 100 grams, Radix Glycyrrhizae, pulverize, cross 100 mesh sieves, then add lanoline 300 grams and 200 grams, vaseline, stir and get final product.
Experimental example
Diagnostic criteria
Reference " internal medicine " (Chen Haozhu. practical internal medicine [M]. the 13rd edition. Beijing: People's Health Publisher, 2009.2364-2370.)) formulate diagnostic criteria, disease see there is suddenly big toe, open up toe, stamp, place's simple joint red and swollen heat pain such as knee joint, or urate is increased, Effects of Colchicine In Treating has specially good effect, and synovial bursa fluid inspection finds urate crystal.
Choose patient 200 example meeting above-mentioned standard, wherein man 100 example, female 100 example; 39 ~ 63 years old age, average 46 years old.
Ointment obtained in embodiment is used to treat, every day 3 times, each affected part using 10 grams of ointments to be evenly coated in swelling pain, continuously treatment 7 days.
Criterion of therapeutical effect
Reference " Chinese medical disease Standardization of diagnosis and curative effect " (State Administration of Traditional Chinese Medicine. Chinese medical disease Standardization of diagnosis and curative effect [M]. Nanjing: publishing house of Nanjing University, 1994.50-51.) formulate.Cure: arthralgia, swelling disappear, and blood uric acid is normal, without recurrence in March.Take a turn for the better: arthralgia, swelling alleviate, have recurrence in March but treat and still can alleviate, blood uric acid declines.Invalid: arthralgia, swelling etc. are without significant change, and blood uric acid is unchanged.
Result
Through treatment, find the arthralgia of all patients, swelling disappearance, blood routine examination blood uric acid within normal range, and follows up a case by regular visits to 3 months without recurrence.Do not find obvious untoward reaction over the course for the treatment of.
Model case
Wang, man, 45 years old, suffer from gout for many years, due to work relationship, often treat with courtesy, the tall and big obesity of build, blood uric acid, lipids contents all exceed normal range, two sufficient big toes, the frequent repeatability congestion and swelling pain of knee joint, when taking medicine, symptom slightly takes a turn for the better, and after drug withdrawal, warp is normal repeatedly, ointment obtained in embodiment is used to treat, every day 3 times, each affected part using 10 grams of ointments to be evenly coated in swelling pain, continuously treatment 7 days.Arthralgia, the swelling of patient disappear, and blood routine examination blood uric acid within normal range, and follows up a case by regular visits to 3 months without recurrence.
Claims (3)
1. treat the pharmaceutical composition of gout for one kind, it is characterized in that, it is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, Herba asplenii trichomanis 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30 parts, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle steep 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts and 10 parts, Radix Glycyrrhizae.
2. the pharmaceutical composition for the treatment of gout according to claim 1, is characterized in that, described pharmaceutical composition can be tablet, dispersible tablet, ointment or suppository.
3. the purposes of compositions in the medicine of preparation treatment gout, it is characterized in that, described medicine is made up by weight of following bulk drugs: beautiful hieracioides 50 parts, Herba asplenii trichomanis 50 parts, RADIX DIPLOCCISIAE 40 parts, Herba speranskiae tuberculatae 45 parts, pilea mongolica 40 parts, Cortex Meliosmatis rigidae Radicis 30 parts, Herba Ainsliaeae Latifoliae 35 parts, Herba tiarellae polyphyllae 30 parts, Cor Cervi grass 30 parts, triangle steep 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts and 10 parts, Radix Glycyrrhizae.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510195261.8A CN104740029B (en) | 2015-04-23 | 2015-04-23 | A kind of pharmaceutical composition for the treatment of gout |
| CN201510585103.3A CN105125704B (en) | 2015-04-23 | 2015-04-23 | A kind of compositions purposes in the medicine of preparation treatment gout |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510195261.8A CN104740029B (en) | 2015-04-23 | 2015-04-23 | A kind of pharmaceutical composition for the treatment of gout |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510585103.3A Division CN105125704B (en) | 2015-04-23 | 2015-04-23 | A kind of compositions purposes in the medicine of preparation treatment gout |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104740029A true CN104740029A (en) | 2015-07-01 |
| CN104740029B CN104740029B (en) | 2015-12-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510585103.3A Expired - Fee Related CN105125704B (en) | 2015-04-23 | 2015-04-23 | A kind of compositions purposes in the medicine of preparation treatment gout |
| CN201510195261.8A Expired - Fee Related CN104740029B (en) | 2015-04-23 | 2015-04-23 | A kind of pharmaceutical composition for the treatment of gout |
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| CN201510585103.3A Expired - Fee Related CN105125704B (en) | 2015-04-23 | 2015-04-23 | A kind of compositions purposes in the medicine of preparation treatment gout |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732498A (en) * | 2008-11-17 | 2010-06-16 | 任风辉 | Formula of Chinese medicament for treating gout |
| CN102793878A (en) * | 2012-09-03 | 2012-11-28 | 吴鎏桢 | Gout fast analgesic paste |
| CN104147377A (en) * | 2014-09-04 | 2014-11-19 | 张湘君 | Traditional Chinese medicinal preparation for treating gout disease |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105106717A (en) * | 2014-02-08 | 2015-12-02 | 吴杰 | Traditional Chinese medicine composition, preparation method and health product made from traditional Chinese medicine composition |
-
2015
- 2015-04-23 CN CN201510585103.3A patent/CN105125704B/en not_active Expired - Fee Related
- 2015-04-23 CN CN201510195261.8A patent/CN104740029B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732498A (en) * | 2008-11-17 | 2010-06-16 | 任风辉 | Formula of Chinese medicament for treating gout |
| CN102793878A (en) * | 2012-09-03 | 2012-11-28 | 吴鎏桢 | Gout fast analgesic paste |
| CN104147377A (en) * | 2014-09-04 | 2014-11-19 | 张湘君 | Traditional Chinese medicinal preparation for treating gout disease |
Non-Patent Citations (2)
| Title |
|---|
| 杨芳，等: "中医外治法治疗痛风性关节炎研究现状", 《新中医》 * |
| 邱爽: "中药外敷法对痛风急性关节炎期疗效研究", 《实用中医内科杂志》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105125704B (en) | 2016-09-28 |
| CN105125704A (en) | 2015-12-09 |
| CN104740029B (en) | 2015-12-09 |
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| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhu Guangyun Inventor after: Qiu Hong Inventor after: Liu Hongjun Inventor before: Wang Ailing |
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| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20151102 Address after: Chinese Medicine Hospital No. 24 Feicheng Changshan street 271600 Shandong city of Tai'an province Feicheng City Applicant after: Zhu Guangyun Address before: 054000, No. 9, middle street, Luo Luo Road, Xingtai County, Xingtai, Hebei Applicant before: Wang Ailing |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151209 Termination date: 20170423 |
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| CF01 | Termination of patent right due to non-payment of annual fee |