CN104398894A - Traditional Chinese medicinal nasal drops for treating chronic rhinitis - Google Patents
Traditional Chinese medicinal nasal drops for treating chronic rhinitis Download PDFInfo
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- CN104398894A CN104398894A CN201410741215.9A CN201410741215A CN104398894A CN 104398894 A CN104398894 A CN 104398894A CN 201410741215 A CN201410741215 A CN 201410741215A CN 104398894 A CN104398894 A CN 104398894A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses traditional Chinese medicinal nasal drops for treating chronic rhinitis. The traditional Chinese medicinal nasal drops are prepared from the following traditional Chinese medicinal materials: 10 to 30 grams of Japanese xylosma barks, 10 to 30 grams of Chinese milkvetch seeds, 2 to 8 grams of common crape myrtle leaves, 1 to 5 grams of wisteria roots, 1 to 5 grams of ramie leaves and 1 to 5 grams of henon bamboo juvenile leaves. A preparation method comprises the steps of putting the traditional Chinese medicinal materials in a decocting device according to a proportion, and adding 1,000 milliliters of pure water; impregnating the traditional Chinese medicinal materials for half an hour to fully wet the traditional Chinese medicinal materials to facilitate full decoction; boiling the traditional Chinese medicinal materials with strong fire, decocting the traditional Chinese medicinal materials for 30 minutes with soft fire, and filtering medicinal residues to obtain traditional Chinese medicinal decoction; heating and concentrating the traditional Chinese medicinal decoction to 200 milliliters to obtain the traditional Chinese medicinal nasal drops. Compared with the prior art, the traditional Chinese medicinal nasal drops for treating chronic rhinitis have the beneficial effects that a using method is convenient, the traditional Chinese medicinal nasal drops have significant curative effects, high efficacy, low recurrence rate and low cost, and side effects are avoided.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine nasal drop for the treatment of chronic rhinitis.
Background technology
Chronic rhinitis is common continuing more than 4 weeks or chronic inflammatory disease under the nasal mucosa of inflammation recurrent exerbation and mucosa, and cardinal symptom is had a stuffy nose, and the traditional Chinese medical science is called " stuffy nose ".Clinical manifestation is mainly intermittence or alternately has a stuffy nose, a little mucus or purulence nasal mucus, headache, olfactory disorder, concha nasalis inferior swelling, smooth surface are moistening, in kermesinus, the soft high resilience of mucosa, can occur depression with probe compressing, remove probe and restore to the original state immediately, this disease can cause patient's giddy, headache so that affect the mental status.The cause of disease of chronic rhinitis is generally that affection of exogenous wind-cold or wind heat are not controlled or treated thoroughly, and evil poison is detained blood stasis, and now sniffle increases the weight of.
Current clinical treatment rhinitis adopts Western medicine topical therapeutic mostly, and Western medicine majority can destroy the normal physiological structure of nasal cavity, and late result can not be satisfactory, and treatment cost is high.Western medicine antibiotics can easily produce drug resistance and toxic and side effects to pathogenic bacterium simultaneously, and the problems such as the reaction of medicamentous rhinitis, systemic toxicity profiles, arrhythmia easily appear in the local Western medicine 1% nitrofural ephedrine nasal drop as conventional.
At present, there is onset slowly in the Chinese medicine of existing orally taken for curing rhinitis, be difficult to the shortcoming improving pathological tissues environment, can not patients symptomatic allowed at short notice to alleviate rapidly, effect be unsatisfactory simultaneously.
Summary of the invention
The object of the invention is exactly the defect in order to make up prior art, provides a kind of instant effect, evident in efficacy, relapse rate is low, has no side effect, the Chinese medicine nasal drop for the treatment of chronic rhinitis that cost is low, realizes particular by following technical scheme:
Treat a Chinese medicine nasal drop for chronic rhinitis, be made up of the Chinese crude drug of following weight: Cortex Xylosmae japonici 10 ~ 30g, Semen astragali sinici 10 ~ 30g, Folium Lagerstroemiae Indicae 2 ~ 8g, Radix wisteriae sinensis 1 ~ 5g, ramie leaf 1 ~ 5g, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 1 ~ 5g.
Preferably, a kind of Chinese medicine nasal drop for the treatment of chronic rhinitis, is made up of the Chinese crude drug of following weight: Cortex Xylosmae japonici 20g, Semen astragali sinici 20g, Folium Lagerstroemiae Indicae 5g, Radix wisteriae sinensis 3g, ramie leaf 3g, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 3g.
The preparation method of the Chinese medicine nasal drop of above-mentioned treatment chronic rhinitis is: first the Chinese crude drug of above-mentioned weight is put into drug-decocting appliance, adds pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
The source of the above-mentioned Chinese crude drug that the present invention selects and pharmacologically active as follows:
Cortex Xylosmae japonici: [source] is the bark of Flacourtiaceae plant Xylosmae japonici.[function cures mainly] dampness, heat extraction.Harness the Yellow River subcutaneous ulcer, scrofula, sore festers.
Semen astragali sinici: [source] is the seed of leguminous plant Herba Astragali Melilotoidis (Herba Astragali Sinici).[function cures mainly] dispelling pathogenic wind for improving eyesight.Main conjunctival congestion and swelling pain.
Folium Lagerstroemiae Indicae: [source] is the leaf of Lythraceae plant Lagerstroemia indica L..[function cures mainly] controls dysentery, eczema, wound hemorrhage.
Radix wisteriae sinensis: [source] is the root of leguminous plant Caulis wisteriae sinensis.[function cures mainly] expelling wind and removing dampness; Relaxing muscles and tendons and activating QI and blood in the collateral.Main gout; Arthromyodynia.
Ramie leaf: [source] is the leaf of contrayerva Boehmeria.[function cures mainly] removing heat from blood, hemostasis, dissipating blood stasis.Control spitting of blood, spit blood, stranguria with blood, hematuria, swelling and pain of anus, red from leukorrhagia, fall and flutter blood stasis, wound hemorrhage, acute mastitis, erysipelas.
Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle: the spire that [source] does not put for the volume of grass phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.[function cures mainly] to clear away heart-fire relieving restlessness, relieves heat and thirst.
The using method of Chinese medicine nasal drop of the present invention is: each every 2, side, and morning and evening every day each use 1 time, dripping with 30 days is continuously a course for the treatment of.
Compared to existing technology, its beneficial effect is the Chinese medicine nasal drop for the treatment of chronic rhinitis of the present invention: using method is easy, evident in efficacy, instant effect, relapse rate are low, have no side effect, cost is low.
detailed description of the invention:
Below in conjunction with embodiment and case, the present invention is further illustrated.
Embodiment 1:
Take Cortex Xylosmae japonici 10g, Semen astragali sinici 30g, Folium Lagerstroemiae Indicae 2g, Radix wisteriae sinensis 5g, ramie leaf 1g, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 5g put into drug-decocting appliance, add pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
Embodiment 2:
Take Cortex Xylosmae japonici 30g, Semen astragali sinici 10g, Folium Lagerstroemiae Indicae 8g, Radix wisteriae sinensis 1g, ramie leaf 5g, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 1g put into drug-decocting appliance, add pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
Embodiment 3:
Take Cortex Xylosmae japonici 20g, Semen astragali sinici 20g, Folium Lagerstroemiae Indicae 5g, Radix wisteriae sinensis 3g, ramie leaf 3g, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 3g put into drug-decocting appliance, add pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
Clinical testing data:
For checking the therapeutic effect of Chinese medicine nasal drop of the present invention, choose the routine chronic rhinitis patient of Liuan City, Anhui Province Shucheng County 140, wherein male 72 example, women 68 example, the range of age 21 ~ 62 years old, 39 years old mean age.Diagnosis basis: (1) to continue nasal obstruction for a long time, or intermittent, alternately have a stuffy nose, nasal mucus amount mostly is cardinal symptom; Or with diseases such as giddy, hypomnesis, insomnia, tinnitus, the inaccessible senses of in ear.(2) course of disease is longer, exacerbation of symptoms after tired, sense is cold; Easy concurrent bulge of the ear, deafness.(3) nasal cavity checks mucous hyperemia, and take on a red color or kermesinus, nasal mucosa swelling is based on concha nasalis inferior.
Therapeutic Method:
140 routine patient's stochastic averagina are divided into four groups, are respectively matched group, treatment group 1, treatment group 2 and treatment group 3, often organize 35 routine patients.Matched group adopts 1% nitrofural ephedrine nasal drop to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.Treatment group 1 adopts the Chinese medicine nasal drop of the embodiment of the present invention 1 to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.Treatment group 2 adopts the Chinese medicine nasal drop of the embodiment of the present invention 2 to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.Treatment group 3 adopts the Chinese medicine nasal drop of the embodiment of the present invention 3 to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.
Efficacy assessment standard:
Cure: the transference cures such as nasal obstruction, watery nasal discharge, nasal membrane swelling is disappeared, and nasal cavity inspection is normal, and more than 3 months without recurrence.
Effective: the symptoms such as nasal obstruction, watery nasal discharge alleviate, and nasal membrane swelling is obviously alleviated, local sign is obviously improved.
Invalid: sings and symptoms is not improved.
Therapeutic effect:
Matched group: cure 12 examples, account for 34.3%; Effective 16 examples, account for 45.7%; Invalid 7 examples; Total effective rate 80%; 8 example recurrences in the patient cured after 3 months, relapse rate 66.7%.
Treatment group 1: cure 26 examples, account for 74.3%; Effective 9 examples, account for 25.7%; Invalid 0 example; Total effective rate 100%; 2 example recurrences in the patient cured after 3 months, relapse rate 7.7%.
Treatment group 2: cure 24 examples, account for 68.6%; Effective 11 examples, account for 31.4%; Invalid 0 example; Total effective rate 100%; 3 example recurrences in the patient cured after 3 months, relapse rate 12.5%.
Treatment group 3: cure 32 examples, account for 91.4%; Effective 3 examples, account for 8.6%; Invalid 0 example; Total effective rate 100%; 1 example recurrence in the patient cured after 3 months, relapse rate 3.1%.
As can be seen from above-mentioned therapeutic outcome, the Chinese medicine nasal drop of the present invention's three embodiments all has effect of well treatment chronic rhinitis, total effective rate reaches 100%, wherein, the cure rate of the Chinese medicine nasal drop of embodiment 3 is the highest, reach 91.4%, relapse rate is minimum, achieves beyond thought effect.
After treatment, carry out Effect of follow-up visit by telephone to whole 140 routine patients above, follow up time is 3 months ~ 1 year.Do not find any untoward reaction.
Be more than specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Claims (2)
1. treat a Chinese medicine nasal drop for chronic rhinitis, it is characterized in that: be made up of the Chinese crude drug of following weight: Cortex Xylosmae japonici 10 ~ 30g, Semen astragali sinici 10 ~ 30g, Folium Lagerstroemiae Indicae 2 ~ 8g, Radix wisteriae sinensis 1 ~ 5g, ramie leaf 1 ~ 5g, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 1 ~ 5g; Preparation method is: first the Chinese crude drug of above-mentioned weight is put into drug-decocting appliance, adds pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
2. a kind of Chinese medicine nasal drop for the treatment of chronic rhinitis according to claim 1, is characterized in that: be made up of the Chinese crude drug of following weight: Cortex Xylosmae japonici 20g, Semen astragali sinici 20g, Folium Lagerstroemiae Indicae 5g, Radix wisteriae sinensis 3g, ramie leaf 3g, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 3g.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410741215.9A CN104398894A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal nasal drops for treating chronic rhinitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410741215.9A CN104398894A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal nasal drops for treating chronic rhinitis |
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| CN201410741215.9A Pending CN104398894A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal nasal drops for treating chronic rhinitis |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1290541A (en) * | 2000-09-22 | 2001-04-11 | 刘世钱 | Nose drops for rhinitis |
| CN101152252A (en) * | 2007-09-20 | 2008-04-02 | 吴月 | Traditional Chinese medicine for treating chronic rhinitis |
| CN101185680A (en) * | 2007-12-11 | 2008-05-28 | 徐生富 | Collunarium medicine for treating chronic rhinitis |
| CN101313938A (en) * | 2008-07-11 | 2008-12-03 | 吉林省辉南天泰药业股份有限公司 | Magnolia flower volatile oil spray for nose |
-
2014
- 2014-12-09 CN CN201410741215.9A patent/CN104398894A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1290541A (en) * | 2000-09-22 | 2001-04-11 | 刘世钱 | Nose drops for rhinitis |
| CN101152252A (en) * | 2007-09-20 | 2008-04-02 | 吴月 | Traditional Chinese medicine for treating chronic rhinitis |
| CN101185680A (en) * | 2007-12-11 | 2008-05-28 | 徐生富 | Collunarium medicine for treating chronic rhinitis |
| CN101313938A (en) * | 2008-07-11 | 2008-12-03 | 吉林省辉南天泰药业股份有限公司 | Magnolia flower volatile oil spray for nose |
Non-Patent Citations (1)
| Title |
|---|
| 彭序明: "中药滴鼻液治疗急慢性鼻炎92例的临床观察", 《云南中医中药杂志》 * |
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Application publication date: 20150311 |