CN1943738B - A medicine for treatment of chronic nasosinusitis - Google Patents
A medicine for treatment of chronic nasosinusitis Download PDFInfo
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- CN1943738B CN1943738B CN2006100693744A CN200610069374A CN1943738B CN 1943738 B CN1943738 B CN 1943738B CN 2006100693744 A CN2006100693744 A CN 2006100693744A CN 200610069374 A CN200610069374 A CN 200610069374A CN 1943738 B CN1943738 B CN 1943738B
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Abstract
This invention relates to a kind of medicinal preparation which has the therapeutic function of chronic nasosinusitis. It is characterized in that the medicament is made up of some high grade raw materials including Lonicera japonica Thunb, Dendranthema morifolium, Magnolia liliflora, Fructus xanthii, Herba Menthae, Radix Angelicae Dahuricae, Manchurian Wildginger, Herba Taraxaci, Foliumisatidis, Houttuynia cordata, Ligusticum wallichii, Radix Angelica, Scutellaria, Semen Coicis Coix lachrymal, Gypsum Fibrosuum, Radix Glycyrrhizae and so on. All the raw materials are mixed according to the definite ratio of weight. The medicament is decocted and taken by oral administration. A dosage is taken in a day and fifteen days as a course of treatment. It is characterized in its high curative ratio, obvious therapeutic effectiveness, symptoms removed rapidly, non-toxic side effectiveness, lower cost of therapy, non-relapse and capable of eliminating pains radically. In all, the medicament can be used in therapy of chronic nasosinusitis effectively. According to clinical trial, the effective rate, the effectual rate and the cure rate of the medicament is up to 96.7%, 87.9% and 63.7%, respectively.
Description
Affiliated technical field
The present invention relates to take Chinese herbal medicine, specifically a kind of medicine for the treatment of chronic sinusitis in a kind of.
Background technology
Chronic sinusitis is the able-bodied disease of a kind of serious harm human body, is the suppurative inflammation of nasal sinuses mucosa, often is secondary to acute purulent nasosinusitis.This chronic sinusitis inflammation can be confined to a nasal sinuses, but more common with many nasal sinuses or full nasal sinuses, the traditional Chinese medical science is referred to as chronic sinusitis, sinusitis with purulent discharge, control brain acute diseases such as cholera and sunstroke.Its main pathogenic factor doctor trained in Western medicine is thought acute purulent nasosinusitis malpractice or outbreak repeatedly, and changes chronic sinusitis into; The traditional Chinese medical science thinks that pathogenic heat are accumulate lung, the nose key that steam to burn, damp and hot delay, numbness resistance nasal sinuses venation, and evil poison is detained, stasis of blood resistance nasal sinuses QI and blood, asthenia of pulmonosplenic qi, the evil hole key that stagnates, the hepatic and renal YIN deficiency, the erosion nasal sinuses burns.Along with the quickening of modern life rhythm, the trend that this disease has age of onset rejuvenation, increasing the weight of of pain degree, morbidity colony to generalize.This sick method of treatment mainly contains and take Chinese herbs decoction, Chinese patent medicine, Western medicine and use external nose drops etc., but the effect of various Therapeutic Method and pluses and minuses is different again at present.Take the Chinese herbs decoction Therapeutic Method, organic conception from the traditional Chinese medical science, from starting with of disease at all, reach collateral dredging and rush down the strong kidney of poison, blood circulation promoting and blood stasis dispelling, adjusting lung spleen, positive liver, promoting the circulation of QI to relieve pain, make inflammation disappeared, have a headache gone down, olfactory sensation recovered, thereby reach the basic goal of treatment, but traditional Chinese herbs decoction treatment chronic sinusitis, the effect performance is slower, and the treatment effective percentage is not high, can not in time remove patient's misery.Taking the Chinese patent drugs for treatment method, mainly is to take BIYANKANG, BIYANLING sheet etc., and curative effect is slow, and Time of Administration is long, and cure rate is low.Take the western medicine method, the efficacy of a drug can reach diseased region fast, effectively reach pain relieving, antiinflammatory effect, make patient's ailing puzzlement of getting off quickly, but because its treatment principle is antiinflammatory, pain relieving, produce ailing basic reason and can not remove, pain easily recurs after the drug withdrawal, cure rate is low, and side effect is bigger.Use external nose drops Therapeutic Method, antiinflammatory rapidly, pain relieving produce ailing basic reason but can not remove, also easily recurrence after the drug withdrawal, and cure rate is low.
Summary of the invention
Purpose of the present invention is exactly for solving chronic sinusitis patient's misery, remove this disease to patient's the spirit and the dual harm of body and mind, a kind of cure rate height, instant effect are provided, have no side effect, treat cost is low, can remove the generation slight illness basic reason, nothing recurrence, and take Chinese herbal medicine in the specially good effect of treatment chronic sinusitis.
Solution of the present invention is based on motherland's medical science to pathogenetic understanding of chronic sinusitis and Therapeutic Principle, with reference to modern pharmacology research, selects for use the high-quality Chinese herbal medicine to carry out reasonable compatibility, in order to effective treatment chronic sinusitis.The present invention treat chronic sinusitis in to take Chinese herbal medicine formulated by pure Chinese medicine, without any side effects to human body.
The technical scheme that the present invention takes is: it is as follows that the present invention treats prescription and the weight proportion of taking Chinese herbal medicine in the chronic sinusitis: Flos Lonicerae 5-30 part, Flos Chrysanthemi 15-20 part, Flos Magnoliae 5-15 part, Fructus Xanthii 10-20 part, Herba Menthae 8-15 part, Radix Angelicae Dahuricae 5-15 part, Herba Asari 3-6 part, Herba Taraxaci 10-30 part, Folium Isatidis 10-30 part, Herba Houttuyniae 10-30 part, Rhizoma Chuanxiong 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Scutellariae 10-15 part, Semen Coicis 10-30 part, Gypsum Fibrosum 10-30 part, Radix Glycyrrhizae 3-6 part.Above-mentioned each Chinese herbal medicine medicine is prepared by weight proportion, after decocting, is taken, every day potion, 15 days is a course of treatment.Use the above-mentioned prescription treatment chronic sinusitis of the present invention's Chinese herbal medicine for oral administration, the cure rate height, curative effect is obvious, and it is rapid to eliminate symptom, has no side effect, and the treatment cost is low, can remove to produce ailing basic reason.Through clinical trial, effective percentage reaches 96.7%, and obvious effective rate reaches 87.9%, and cure rate reaches 63.7%.
Prove according to Traditional Chinese medical theory and modern medicine study, the nature and flavor of various composition medicines in the Chinese herbal medicine of the present invention, return through and useful effect as follows:
Flos Lonicerae: sweet, cold, return lung, spleen, large intestine channel.Heat-clearing and toxic substances removing.Be used for affection due to external wind and heat or epidemic febrile disease from the beginning of.
Flos Chrysanthemi: hot, sweet, bitter, be slightly cold, return liver, lung meridian.Wind and heat dispersing, detoxifcation makes eye bright.Be used for affection due to external wind and heat and epidemic febrile disease from the beginning of.
Flos Magnoliae: hot, warm, attach to the lung and stomach meridians.Dispersing wind and cold, clearing the nasal passage.Be used for headache due to invasion of exogenous pathogens, particularly the nasosinusitis headache nasal obstruction.
Flos Carthami: hot, warm, GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, stimulate the menstrual flow.The disease that is used for hematogenous blockage.
Fructus Xanthii: hot, temperature, bitter, slightly poisonous, return lung meridian.Clearing the nasal passage, wind-damp dispelling, pain relieving.Be used for nasal sinusitis, headache, anosmia, rhinorrhea.
Herba Menthae: hot, cool, return the liver lung meridian.Dispelling wind and heat pathogens, the clear sharp head.Be used for affection due to external wind and heat, have a headache, the person of being slightly cold.
The Radix Angelicae Dahuricae: hot, warm, return lung stomach warp.Dispeiling pathogenic wind and removing dampness, swollen, the pain relieving of the pus that disappears row.Be used for headache due to invasion of exogenous pathogens, supraorbital bone pain.
Herba Asari: hot, warm, return lung, kidney channel.Dispersing cold for relieving pain, a surname's clearing the nasal passage.Be used for headache, arthralgia pain, property is apt to away scurry, dispersing cold for relieving pain.
Herba Taraxaci: bitter, sweet, cold, return liver, stomach warp.Heat-clearing and toxic substances removing.Be used for swollen bitterly skin infection of pyretic toxicity and interior pain and wait disease.
Folium Isatidis: bitter, Great Cold, GUIXIN, lung, stomach warp.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Be used for warm febrile disease, headache, pharyngalgia.
Herba Houttuyniae: hot, be slightly cold, return lung meridian.Heat-clearing and toxic substances removing, evacuation of pus, diuresis.Being used for evacuation of pus disappears bitterly.
Rhizoma Chuanxiong: hot, warm, return liver and gall, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for wind-expelling pain-stopping, the up head of energy is for controlling the key medicine of headache.
Radix Angelicae Sinensis: sweet, Xin Wen, return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, pain relieving.Be used for reducing swelling and alleviating pain, evacuation of pus granulation promoting effect.
Radix Scutellariae: bitter, cold, return lung, gallbladder, stomach, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis.Be used for diseases such as haematemesis due to the high Sheng of interior-heat, the absurd row of forcing blood, hemoptysis, metrorrhagia.
Semen Coicis: sweet, light, be slightly cold, return spleen, stomach, lung meridian.Promoting diuresis to eliminate damp pathogen, spleen invigorating, clearing away heat and discharging pus.Be used for diseases such as dysuria, damp-heat in lower-JIAO edema.
Gypsum Fibrosum: hot, sweet, in Great Cold, attach to the lung and stomach meridians.Clearing away heat-fire, relieving restlessness is quenched the thirst.Be used for headache, toothache due to the flaming up of stomach-fire.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, relieving spasm to stop pain.Be used for laryngopharynx swelling and pain.
This side has the effect of diffusing wind dehumidifying, heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, a surname's stuffy nose relieving hole, detumescence and apocenosis.Fructus Xanthii in the side, Flos Magnoliae two flavors are all gone into lung meridian, diffusing evil, the kind clearing the nasal passage of dispelling wind; The hot temperature of the Radix Angelicae Dahuricae is sensible, cold expelling dispels the wind, and obvious anti-inflammatory analgesic is arranged; The hot cool fragrance of Herba Menthae is walked string, and is kind can exorcising evil spirits turbid, opens clearing the nasal passage; Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong have protective effect with promoting blood circulation and stopping pain, detumescence and apocenosis to the nasal sinuses vascular endothelial cell.Join Flos Lonicerae, Flos Chrysanthemi, Herba Taraxaci, Folium Isatidis, Herba Houttuyniae strengthening the merit of heat-clearing and toxic substances removing, Diplococcus pneumoniae, staphylococcus aureus, streptococcus, the Bacillus proteus of sinusitis had inhibitory action in various degree; Herba Asari has the merit of wind-expelling pain-stopping, suitable clearing the nasal passage.The effect that Radix Scutellariae, Gypsum Fibrosum have clearing away heat-fire, end Yangming Channel headache, the favourable fiery eliminating dampness by diuresis of Semen Coicis, spleen invigorating, clearing away heat and discharging pus; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, relieving spasm to stop pain.All medicines close it, and the merit of the blood and relieving pain of accepting orders for repairs or processing altogether plays anti-inflammatory analgetic, improves hemorheology, improves the effect of blood samples of patients circulation, thereby reach the purpose of treatment chronic sinusitis.
For showing the curative effect of the present invention's Chinese herbal medicine for oral administration, the present invention's Chinese herbal medicine for oral administration has been carried out the clinical comparison test.According to statistics, test group is totally 91 examples, wherein: male 57 examples, women 34 examples, age is at 15-69 between year, 38 years old mean age, medical history 6 months 1 years, average 2.1 years, Therapeutic Method is for taking the present invention's Chinese herbal medicine for oral administration, every day potion, 15 days was 1 course of treatment, took one course of treatment of this medicine; Matched group is totally 67 examples, wherein: male 39 examples, women 28 examples, the age is between 19-51 year, medical history 4 months 1 years, average 1.9 years, Therapeutic Method was for one course of treatment of general Drug therapy.And it is as follows to formulate criterion of therapeutical effect:
Recovery from illness: clinical pain symptom disappears, nasal obstruction, pus tears transference cure, and it is normal that olfactory sensation recovers, and do not have yellow purulent secretion, and nasal cavity is clear, and it is normal that mucosa recovers, and normally followed up a case by regular visits to 1 one 3 years, do not have recurrence.
Produce effects: clinical pain symptom significantly alleviates, and nasal obstruction, pus tears symptom disappear substantially, and it is normal that olfactory sensation recovers, and yellow purulent secretion significantly reduces, and nasal cavity is clear, and it is normal that mucosa recovers.
Take a turn for the better: clinical pain symptom alleviates, and nasal obstruction, pus tears symptom disappear substantially, and yellow purulent secretion reduces, and nasal cavity is clear substantially, and mucosa recovers to some extent.
Invalid: clinical pain symptom and sign do not have the improver.
The upright shelves of warp stay to be looked into and follow up survey, and carries out the statistical analysis contrast, and statistical result is as follows:
Table 1, test group curative effect situation
2, matched group curative effect situation
The specific embodiment
The present invention is further described below in conjunction with embodiment.
Select the high-quality Chinese herbal medicine for use by following weight proportion: Flos Lonicerae 25g, Flos Chrysanthemi 17g, Flos Magnoliae 12g, Fructus Xanthii 18g, Herba Menthae 10g, Radix Angelicae Dahuricae 10g, Herba Asari 5g, Herba Taraxaci 25g, Folium Isatidis 15g, Herba Houttuyniae 25g, Rhizoma Chuanxiong 12g, Radix Angelicae Sinensis 10g, Radix Scutellariae 12g, Semen Coicis 20g, Gypsum Fibrosum 25g, Radix Glycyrrhizae 6g.Above-mentioned each medicine preparation is mixed, after decocting, took for 1 course of treatment, every day potion, per 15 days was 1 course of treatment, took 1-2 course of treatment of this medicine, can effectively control chronic sinusitis.From above-mentioned clinical treatment contrast test, picked at random 4 examples are further to show the therapeutic effect of Chinese patent medicine of the present invention.
Example 1: Zhang Jiazhen, man, 22 years old, Liu market town, Donga County Xiao Feng people from village went to a doctor on October 22nd, 2002, and it is surplus to suffer from chronic sinusitis 8 years, unrelenting headache, nasal obstruction, rhinorrhea, breath is obstructed, increases the weight of in nearly 3 years, once repeatedly capable maxillary sinus puncture, partial inferior turbinectomy in the last year bilateral though the postoperative nasal obstruction has improvement, but still is felt dizzy distending pain, tears are many and turbid, and it is low voice speaking to have a stuffy nose, bitter taste in the mouth and dry throat, come to go to a doctor, see the pale distortion of both sides middle nasal concha, middle inferior nasal meatus has a large amount of sticking purulent secretions, both sides maxillary sinus hole wall thickening is seen in the inspection of X-ray sheet, the centration increase in density, and puncture antral is sticking purulent secretion, amount is many, do not have stench flavor, red tongue with thin fur is white little greasy, moderate pulse.Card belongs to the clearing moist heat key, clear YANG failing to ascend, and turbid pathogen is not changed, phlegm-coagulation and blood-stagnation.Behind 15 doses of clothes the present invention Chinese herbal medicine for oral administration, the turbid tears of conscious headache nasal obstruction stream obviously improve, and first is improved slightly in the nose of both sides, and middle inferior nasal meatus does not have secretions.After obeying 15 doses again, headache nasal obstruction transference cure is followed up a case by regular visits to and was not had recurrence in 3 years.
Example 2: Zhao Xinglong, man, 37 years old, Liu market town, Donga County Da Zhao village peasant.On March 16th, 2004 examined, and patient's nasion and superciliary ridge place pain relate to left temporo, the time behind the nose two of the turbid tears companions of resorption white swell, the photophobia tear that overflows, blurred vision is surplus March, and history of repeated attack is previously arranged, through ophthalmologic examination, intraocular pressure, interior external eyes all do not have obvious pain and become, patient's emaciated physique, and the palm sole of the foot is scorching hot, the light tenderness in superciliary ridge place, eyeball does not have tenderness, and conjunctive bulbi is not congested, and rhinoscopy sees that both sides concha nasalis swelling unbearably, sticking pus is arranged behind Zhong Dao rear end and the olfactory cleft, pharynx rear wall mucosa drying, the diagnosing chronic sphenoiditis, take 5 doses of the present invention's Chinese herbal medicine for oral administration after, the conscious nasion, superciliary ridge place pain and photophobia are clearly better, and cough up phlegm behind the nose and also reduce, and check that pharynx rear wall mucosa is ruddy, the olfactory cleft district is clear, transference cure after 15 doses.Follow up a case by regular visits to no pathological changes recurrence in 2 years.
Example 3: Yang Huaizhong, man, 40 years old.The seven grades of preceding Yangchuan village peasants in town in Yanggu County, go to a doctor in February, 2005.Patient's headache, dizziness, long-term nasal obstruction is year surplus in the of 10, and therapeutic effect is not obvious everywhere.Headache outbreak in the recent period, position pro-jaw, its gesture is as pecking, tending to vomit is had a stuffy nose general, and the few color of tears is clear, the congested swelling of patient's nasal mucosa, there is mucus secretions the middle nasal meatus front upper place, and going up the angle in two eye sockets has obvious tenderness, the tongue fur BOHUANG, the muddy several diseases of arteries and veins belong on the ailment said due to cold or exposure and holding up, fire stagnation is in interior, all disease the knowing of headache nasal obstruction are removed after taking 5 doses of the present invention's Chinese herbal medicine for oral administration, and symptom complete obiteration after 15 doses does not have recurrence so far.
Example 4: Du Tingting, woman, 19 years old.Liaocheng City Dongchangfu District Yu Jidu village village school gives birth to.Go to a doctor in May, 2005.Patient's nasal obstruction of having a headache, it is surplus to flow yellow nasal mucus 2 years, the time heavy when light, school grade descends, to play the beginning pain morning, noon is the heaviest, and is gradually light in the afternoon during morbidity, disappear evening.The diagnosing chronic maxillary sinusitis, take 9 doses of the present invention's Chinese herbal medicine for oral administration after headache light, transference cure after 15 doses does not have recurrence so far.
Below in conjunction with most preferred embodiment the present invention's Chinese herbal medicine for oral administration is described in further detail.Select the high-quality Chinese herbal medicine for use by following weight proportion: Flos Lonicerae 25g, Flos Chrysanthemi 17g, Flos Magnoliae 12g, Fructus Xanthii 18g, Herba Menthae 10g, Radix Angelicae Dahuricae 10g, Herba Asari 5g, Herba Taraxaci 25g, Folium Isatidis 15g, Herba Houttuyniae 25g, Rhizoma Chuanxiong 12g, Radix Angelicae Sinensis 10g, Radix Scutellariae 12g, Semen Coicis 20g, Gypsum Fibrosum 25g, Radix Glycyrrhizae 6g.Above-mentioned each medicine preparation is mixed, after decocting, took for 1 course of treatment, every day potion, per 15 days was 1 course of treatment, took 1-2 course of treatment of this medicine, can effectively control chronic sinusitis.
Claims (2)
1. a medicine for the treatment of chronic sinusitis is characterized in that it is to be made by the herbal raw material medicine of following weight proportioning: Flos Lonicerae 5-30 part, Flos Chrysanthemi 15-20 part, Flos Magnoliae 5-15 part, Fructus Xanthii 10-20 part, Herba Menthae 8-15 part, Radix Angelicae Dahuricae 5-15 part, Herba Asari 3-6 part, Herba Taraxaci 10-30 part, Folium Isatidis 10-30 part, Herba Houttuyniae 10-30 part, Rhizoma Chuanxiong 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Scutellariae 10-15 part, Semen Coicis 10-30 part, Gypsum Fibrosum 10-30 part, Radix Glycyrrhizae 3-6 part.
2. the medicine of treatment chronic sinusitis as claimed in claim 1 is characterized in that wherein the weight proportion of each crude drug is: Flos Lonicerae 25g, Flos Chrysanthemi 17g, Flos Magnoliae 12g, Fructus Xanthii 18g, Herba Menthae 10g, Radix Angelicae Dahuricae 10g, Herba Asari 5g, Herba Taraxaci 25g, Folium Isatidis 15g, Herba Houttuyniae 25g, Rhizoma Chuanxiong 12g, Radix Angelicae Sinensis 10g, Radix Scutellariae 12g, Semen Coicis 20g, Gypsum Fibrosum 25g, Radix Glycyrrhizae 6g.
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| CN2006100693744A CN1943738B (en) | 2006-10-23 | 2006-10-23 | A medicine for treatment of chronic nasosinusitis |
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Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101491621B (en) * | 2009-03-12 | 2011-01-05 | 许建成 | Traditional Chinese medicine composition for treating sinusitis and preparation method thereof |
| CN101524434B (en) * | 2009-03-27 | 2011-04-06 | 冯苏涛 | Antibacterial cream for treating rhinitis and preparation method thereof |
| CN101926901B (en) * | 2010-09-01 | 2011-08-31 | 吴业刚 | Chinese medicinal oral liquid for treating chronic rhinitis and sinusitis and preparation method thereof |
| CN102205026B (en) * | 2011-05-27 | 2013-03-27 | 李佃场 | Chinese medicinal composition for treating children chronic sinusitis and preparation method thereof |
| CN102526459B (en) * | 2012-02-20 | 2014-01-22 | 徐健 | Traditional Chinese medicine composition for treating nasosinusitis and preparation method thereof |
| CN102614306B (en) * | 2012-04-18 | 2013-06-26 | 南阳医学高等专科学校 | Traditional Chinese herbal preparation for treating chronic nasosinusitis |
| CN102670784B (en) * | 2012-05-09 | 2014-06-04 | 王子英 | Chinese medicinal preparation for treating rhinitis and sinusitis |
| CN103386029B (en) * | 2013-07-25 | 2015-04-29 | 马丽 | Traditional Chinese medicine preparation for treating nasosinusitis |
| CN104337919A (en) * | 2014-10-15 | 2015-02-11 | 四川金堂海纳生物医药技术研究所 | Internal medicine for treating nasosinusitis and preparation method thereof |
| CN104840787A (en) * | 2015-05-15 | 2015-08-19 | 石纯满 | Traditional Chinese medicine decoction for treating nasosinusitis and preparation method thereof |
| CN105125823A (en) * | 2015-09-28 | 2015-12-09 | 卞文青 | Medicine preparation for treating chronic nasosinusitis |
| CN105327016A (en) * | 2015-11-26 | 2016-02-17 | 济南舜祥医药科技有限公司 | Sticking plaster for treating rhinitis and preparation method for sticking plaster |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1386542A (en) * | 2002-06-05 | 2002-12-25 | 曹双全 | Chinese-medicinal oral liquid for treating rhinitis and nasosinusitis and its preparing process |
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| CN1386542A (en) * | 2002-06-05 | 2002-12-25 | 曹双全 | Chinese-medicinal oral liquid for treating rhinitis and nasosinusitis and its preparing process |
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