CN104398895A - Traditional Chinese medicinal nasal drops for treating chronic rhinitis - Google Patents
Traditional Chinese medicinal nasal drops for treating chronic rhinitis Download PDFInfo
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- CN104398895A CN104398895A CN201410741233.7A CN201410741233A CN104398895A CN 104398895 A CN104398895 A CN 104398895A CN 201410741233 A CN201410741233 A CN 201410741233A CN 104398895 A CN104398895 A CN 104398895A
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- traditional chinese
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention discloses traditional Chinese medicinal nasal drops for treating chronic rhinitis. The traditional Chinese medicinal nasal drops are prepared from the following traditional Chinese medicinal materials: 20 to 40 grams of przewalski savin leaves, 3 to 11 grams of hemianthus micranthemoides, 3 to 11 grams of caloglossa leprieurii, 3 to 7 grams of remote lemongrass herbs, 3 to 7 grams of dasheen petiole and 1 to 5 grams of jasminum nudiflorum leaves. A preparation method comprises the steps of putting the traditional Chinese medicinal materials in a decocting device according to a proportion, and adding 1,000 milliliters of pure water; impregnating the traditional Chinese medicinal materials for half an hour to fully wet the traditional Chinese medicinal materials to facilitate full decoction; boiling the traditional Chinese medicinal materials with strong fire, decocting the traditional Chinese medicinal materials for 30 minutes with soft fire, and filtering medicinal residues to obtain traditional Chinese medicinal decoction; heating and concentrating the traditional Chinese medicinal decoction to 200 milliliters to obtain the traditional Chinese medicinal nasal drops. Compared with the prior art, the traditional Chinese medicinal nasal drops for treating chronic rhinitis have the benefits that a using method is convenient, the traditional Chinese medicinal nasal drops have significant curative effects, high efficacy, low recurrence rate and low cost, and side effects are avoided.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine nasal drop for the treatment of chronic rhinitis.
Background technology
Chronic rhinitis is common continuing more than 4 weeks or chronic inflammatory disease under the nasal mucosa of inflammation recurrent exerbation and mucosa, and cardinal symptom is had a stuffy nose, and the traditional Chinese medical science is called " stuffy nose ".Clinical manifestation is mainly intermittence or alternately has a stuffy nose, a little mucus or purulence nasal mucus, headache, olfactory disorder, concha nasalis inferior swelling, smooth surface are moistening, in kermesinus, the soft high resilience of mucosa, can occur depression with probe compressing, remove probe and restore to the original state immediately, this disease can cause patient's giddy, headache so that affect the mental status.The cause of disease of chronic rhinitis is generally that affection of exogenous wind-cold or wind heat are not controlled or treated thoroughly, and evil poison is detained blood stasis, and now sniffle increases the weight of.
Current clinical treatment rhinitis adopts Western medicine topical therapeutic mostly, and Western medicine majority can destroy the normal physiological structure of nasal cavity, and late result can not be satisfactory, and treatment cost is high.Western medicine antibiotics can easily produce drug resistance and toxic and side effects to pathogenic bacterium simultaneously, and the problems such as the reaction of medicamentous rhinitis, systemic toxicity profiles, arrhythmia easily appear in the local Western medicine 1% nitrofural ephedrine nasal drop as conventional.
At present, there is onset slowly in the Chinese medicine of existing orally taken for curing rhinitis, be difficult to the shortcoming improving pathological tissues environment, can not patients symptomatic allowed at short notice to alleviate rapidly, effect be unsatisfactory simultaneously.
Summary of the invention
The object of the invention is exactly the defect in order to make up prior art, provides a kind of instant effect, evident in efficacy, relapse rate is low, has no side effect, the Chinese medicine nasal drop for the treatment of chronic rhinitis that cost is low, realizes particular by following technical scheme:
Treat a Chinese medicine nasal drop for chronic rhinitis, be made up of the Chinese crude drug of following weight: Cacumen et folium sabinae przewalskii 20 ~ 40g, Herba Phyllanthi Urinariae 3 ~ 11g, Caloglossa Leprieurii 3 ~ 11g, Herba Cymbopogonis 3 ~ 7g, Petiolus Colocasiae Esculentae 3 ~ 7g, Folium Jasmini Nudiflori 1 ~ 5g.
Preferably, a kind of Chinese medicine nasal drop for the treatment of chronic rhinitis, is made up of the Chinese crude drug of following weight: Cacumen et folium sabinae przewalskii 30g, Herba Phyllanthi Urinariae 7g, Caloglossa Leprieurii 7g, Herba Cymbopogonis 5g, Petiolus Colocasiae Esculentae 5g, Folium Jasmini Nudiflori 3g.
The preparation method of the Chinese medicine nasal drop of above-mentioned treatment chronic rhinitis is: first the Chinese crude drug of above-mentioned weight is put into drug-decocting appliance, adds pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
The source of the above-mentioned Chinese crude drug that the present invention selects and pharmacologically active as follows:
Cacumen et folium sabinae przewalskii: [source] is the leaf of Cupressaceae plant Qilian mountains Chinese juniper.[function cures mainly] stops blooding, antitussive.
Herba Phyllanthi Urinariae: the herb that [source] is euphorbia plant Cacumen Securinegae Suffruticosae or whole herb with root.[function cures mainly] calming liver and clearing heat, promoting diuresis to remove toxic substance.Control enteritis, dysentery, infectious hepatitis, oedema due to nephritis, urinary tract infection, infantile malnutrition, acute catarrhal conjunctivitis corneal nebula, aphtha head sore, innominate toxic swelling.
Caloglossa Leprieurii: [source] is the frond of the U.S. tongue algae of Delesseriaceae plant.[function cures mainly] anthelmintic parasite killing.Main ascariasis.
Herba Cymbopogonis: [source] is the herb of grass Herba Cymbopogonis.[function cures mainly] induces sweat, and dampness removing is relievingd asthma, cough-relieving.The summer-heat that cures the wound is caught a cold, and gonorrhea, rheumatism muscles and bones is ached, chronic tracheitis.
Petiolus Colocasiae Esculentae: [source] is the petiole of aroid taro.[function cures mainly] dispels the wind; Dampness removing; Removing toxic substances; Blood stasis dispelling.Main nettle single board computer rash; Anaphylactoid purpura; Children with Diarrhoea night sweat impetigo; Innominate toxic swelling; Snake head-like infection; Bee sting.
Folium Jasmini Nudiflori: [source] is the blade of Oleaceae plants Flos Jasmini Nudiflori.[function cures mainly] heat clearing away; Dampness removing; Removing toxic substances.Main cold, fever; Urine leaching pain; Pruritus vulvae; Toxic swelling malignant boil; Traumatic injury; Knife injury is hemorrhage.
The using method of Chinese medicine nasal drop of the present invention is: each every 2, side, and morning and evening every day each use 1 time, dripping with 30 days is continuously a course for the treatment of.
Compared to existing technology, its beneficial effect is the Chinese medicine nasal drop for the treatment of chronic rhinitis of the present invention: using method is easy, evident in efficacy, instant effect, relapse rate are low, have no side effect, cost is low.
detailed description of the invention:
Below in conjunction with embodiment and case, the present invention is further illustrated.
Embodiment 1:
Take Cacumen et folium sabinae przewalskii 20g, Herba Phyllanthi Urinariae 11g, Caloglossa Leprieurii 3g, Herba Cymbopogonis 7g, Petiolus Colocasiae Esculentae 3g, Folium Jasmini Nudiflori 5g put into drug-decocting appliance, add pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
Embodiment 2:
Take Cacumen et folium sabinae przewalskii 40g, Herba Phyllanthi Urinariae 3g, Caloglossa Leprieurii 11g, Herba Cymbopogonis 3g, Petiolus Colocasiae Esculentae 7g, Folium Jasmini Nudiflori 1g put into drug-decocting appliance, add pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
Embodiment 3:
Take Cacumen et folium sabinae przewalskii 30g, Herba Phyllanthi Urinariae 7g, Caloglossa Leprieurii 7g, Herba Cymbopogonis 5g, Petiolus Colocasiae Esculentae 5g, Folium Jasmini Nudiflori 3g put into drug-decocting appliance, add pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
Clinical testing data:
For checking the therapeutic effect of Chinese medicine nasal drop of the present invention, choose the routine chronic rhinitis patient in Feidong County, Hefei City, Anhui Province 100, wherein male 56 example, women 44 example, the range of age 17 ~ 55 years old, 37 years old mean age.Diagnosis basis: (1) to continue nasal obstruction for a long time, or intermittent, alternately have a stuffy nose, nasal mucus amount mostly is cardinal symptom; Or with diseases such as giddy, hypomnesis, insomnia, tinnitus, the inaccessible senses of in ear.(2) course of disease is longer, exacerbation of symptoms after tired, sense is cold; Easy concurrent bulge of the ear, deafness.(3) nasal cavity checks mucous hyperemia, and take on a red color or kermesinus, nasal mucosa swelling is based on concha nasalis inferior.
Therapeutic Method:
100 routine patient's stochastic averagina are divided into four groups, are respectively matched group, treatment group 1, treatment group 2 and treatment group 3, often organize 25 routine patients.Matched group adopts 1% nitrofural ephedrine nasal drop to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.Treatment group 1 adopts the Chinese medicine nasal drop of the embodiment of the present invention 1 to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.Treatment group 2 adopts the Chinese medicine nasal drop of the embodiment of the present invention 2 to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.Treatment group 3 adopts the Chinese medicine nasal drop of the embodiment of the present invention 3 to treat, each every 2, side, and morning and evening every day each use 1 time, drips continuously with 30 days.
Efficacy assessment standard:
Cure: the transference cures such as nasal obstruction, watery nasal discharge, nasal membrane swelling is disappeared, and nasal cavity inspection is normal, and more than 3 months without recurrence.
Effective: the symptoms such as nasal obstruction, watery nasal discharge alleviate, and nasal membrane swelling is obviously alleviated, local sign is obviously improved.
Invalid: sings and symptoms is not improved.
Therapeutic effect:
Matched group: cure 7 examples, account for 28%; Effective 12 examples, account for 48%; Invalid 6 examples, account for 24%; Total effective rate 76%; 5 example recurrences in the patient cured after 3 months, relapse rate is 71.4%.
Treatment group 1: cure 14 examples, account for 56%; Effective 11 examples, account for 44%; Invalid 0 example; Total effective rate 100%; 2 example recurrences in the patient cured after 3 months, relapse rate is 14.3%.
Treatment group 2: cure 16 examples, account for 64%; Effective 9 examples, account for 36%; Invalid 0 example; Total effective rate 100%; 1 example recurrence in the patient cured after 3 months, relapse rate is 6.25%.
Treatment group 3: cure 22 examples, account for 88%; Effective 3 examples, account for 12%; Invalid 0 example; Total effective rate 100%; 0 example recurrence in the patient cured after 3 months, relapse rate is 0.
As can be seen from above-mentioned therapeutic outcome, the Chinese medicine nasal drop of the present invention's three embodiments all has effect of well treatment chronic rhinitis, and total effective rate reaches 100%, wherein, the cure rate of the Chinese medicine nasal drop of embodiment 3 is the highest, reaches 88%, relapse rate is minimum, achieves beyond thought effect.
After treatment, carry out Effect of follow-up visit by telephone to whole 100 routine patients above, follow up time is 3 months ~ 1 year.Do not find any untoward reaction.
Be more than specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Claims (2)
1. treat a Chinese medicine nasal drop for chronic rhinitis, it is characterized in that: be made up of the Chinese crude drug of following weight: Cacumen et folium sabinae przewalskii 20 ~ 40g, Herba Phyllanthi Urinariae 3 ~ 11g, Caloglossa Leprieurii 3 ~ 11g, Herba Cymbopogonis 3 ~ 7g, Petiolus Colocasiae Esculentae 3 ~ 7g, Folium Jasmini Nudiflori 1 ~ 5g; Preparation method is: first the Chinese crude drug of above-mentioned weight is put into drug-decocting appliance, adds pure water 1000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 30 minutes, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 200 milliliters, the Chinese medicine nasal drop of chronic rhinitis must be treated.
2. a kind of Chinese medicine nasal drop for the treatment of chronic rhinitis according to claim 1, is characterized in that: be made up of the Chinese crude drug of following weight: Cacumen et folium sabinae przewalskii 30g, Herba Phyllanthi Urinariae 7g, Caloglossa Leprieurii 7g, Herba Cymbopogonis 5g, Petiolus Colocasiae Esculentae 5g, Folium Jasmini Nudiflori 3g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410741233.7A CN104398895A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal nasal drops for treating chronic rhinitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410741233.7A CN104398895A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal nasal drops for treating chronic rhinitis |
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| CN104398895A true CN104398895A (en) | 2015-03-11 |
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| CN201410741233.7A Pending CN104398895A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal nasal drops for treating chronic rhinitis |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020160059A1 (en) * | 2000-09-13 | 2002-10-31 | Wei Xiao | Cinnamomi and poria composition, method to prepare same and uses thereof |
| CN103006893A (en) * | 2013-01-15 | 2013-04-03 | 鲍旭刚 | Medicine for treating chronic rhinitis and preparation method thereof |
-
2014
- 2014-12-09 CN CN201410741233.7A patent/CN104398895A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020160059A1 (en) * | 2000-09-13 | 2002-10-31 | Wei Xiao | Cinnamomi and poria composition, method to prepare same and uses thereof |
| CN103006893A (en) * | 2013-01-15 | 2013-04-03 | 鲍旭刚 | Medicine for treating chronic rhinitis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 康鉴文化编辑部: "《实用泡澡手册：泡出一个好身体》", 31 July 2014, 广东旅游出版社 * |
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Application publication date: 20150311 |
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