CN102266393B - External application medicament for treating allergic rhinitis and preparation method thereof - Google Patents
External application medicament for treating allergic rhinitis and preparation method thereof Download PDFInfo
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- CN102266393B CN102266393B CN2011102197580A CN201110219758A CN102266393B CN 102266393 B CN102266393 B CN 102266393B CN 2011102197580 A CN2011102197580 A CN 2011102197580A CN 201110219758 A CN201110219758 A CN 201110219758A CN 102266393 B CN102266393 B CN 102266393B
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Abstract
The invention discloses an external application medicament for treating allergic rhinitis. The external application medicament is prepared by crushing the following Chinese herbal medicines in part by weight: 15 to 25 parts of manchurian wildginger, 15 to 25 parts of gansui root, 15 to 25 parts of white mustard seed, 6 to 15 parts of biond magnolia flower, 6 to 15 parts of Siberian cocklour fruit, 6 to 15 parts of Chinese honeylocust abnormal fruit, 8 to 12 parts of angelica dahurica, 2 to 8 parts of clove, 2 to 8 parts of raw ephedra, 2 to 8 parts of mint, 2 to 8 parts of borneol and 1 to 3 parts of musk, mixing and blending by ginger juice to form paste. The external application medicament for treating the allergic rhinitis has obvious effects of dispelling wind, freeing lung, promoting qi circulation, blood circulation, inducing resuscitation with aroma and activating nasal cavity. In the observation of the clinical curative effect of 20 patients, 15 patients are cured clinically, and 5 patients are excellent.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of of allergic rhinitis, particularly relate to a kind of liniment for the treatment of of allergic rhinitis, the invention still further relates to the preparation method of this medicine.
Background technology
Allergic rhinitis claims again allergic rhinitis, is the allergic disease of bronchia mucosal, belongs to traditional Chinese medical science nasal sinusitis category.Rhinocnesmus, paroxysmal sneeze shows effect continuously, a large amount of water sample nasal mucus and nasal obstruction are its classical symptom, and normal companioned with headache, hyposmia, nasal sinuses district pain are then empty endlessly dizzy for a long time, are one of nose section commonly encountered diseases, frequently-occurring disease.Allergic rhinitis is many brings out because sucking pollen or stimulus object such as perfume, smoke, paint, newspaper printing ink, deodorizer or other sprays and cold air and pollutants in air etc.The traditional Chinese medical science thinks that allergic rhinitis mostly is the evil poison of affection due to external wind and heat, or the wind and cold invasion and attack, and for a long time and heat-transformation, pathogenic heat are followed through upper steaming, violate and the nose key; Or gallbladder meridian is hot, with through upper criminal, steams the nose key that burns; Or damp-heat in the spleen and stomach, follow stomach through on disturb etc. and to cause.
The western medical treatment allergic rhinitis mostly is the medicine desensitization therapy at present, such as antihistaminic, Anaphylactic mediator resistance release, corticosteroids medicine etc.; Above medicine all needs long-time for oral administration, and is larger to the stimulation of patient's the intestines and stomach, certain side effect is arranged, and curative effect is not very good yet.
Summary of the invention
The liniment that the purpose of this invention is to provide a kind for the treatment of of allergic rhinitis, this medicine have clearing the nasal passage, antianaphylactic effect take Chinese medicine as crude drug, and the treatment of allergic rhinitis effect is remarkable.
Another object of the present invention provides the preparation method of the liniment of this treatment of allergic rhinitis.
The medicine for the treatment of of allergic rhinitis of the present invention is to select Herba Asari, Radix Kansui, Semen Sinapis Albae, Flos Magnoliae, Fructus Xanthii, Fructus Gleditsiae Abnormalis, the Radix Angelicae Dahuricae, Flos Caryophylli, Herba Ephedrae, Herba Menthae, Borneolum Syntheticum, Moschus to make up, so that each medicine produces synergism, thereby the effectively recurrence for the treatment of of allergic rhinitis.Choice of drug Magnoliae Powder wind and cold of the present invention, clearing the nasal passage is monarch drug, and Herba Asari, Herba Ephedrae, the Radix Angelicae Dahuricae, Fructus Xanthii help the Flos Magnoliae lung qi dispersing, and dispersing wind and cold is ministerial drug, and Fructus Gleditsiae Abnormalis, Borneolum Syntheticum, Moschus, Herba Menthae, Flos Caryophylli fragrance are walked to alter, and helping Flos Magnoliae to open the nose key is adjuvant drug; Radix Kansui, Semen Sinapis Albae eliminate the phlegm and relieve oedema or abdominal distension through diuresis or purgation, and strengthen the permeability of medicine for making medicine.Modern medicine thinks that during the rhinitis, the vertical diaphragm edema of nose is plump, and Radix Kansui has very strong elimination edema effect.All medicines share, and have the effect of dispelling wind and ventilating the lung, promoting flow of QI and blood, causing resuscitation with aromatic drugs, a surname's clearing the nasal passage.
The consumption of crude drug component of the present invention is that the inventor draws through a large amount of Exploration and conclusions, and each crude drug amounts of components all has preferably curative effect in the following portions by weight scope.
Herba Asari 15-25, Radix Kansui 15-25, Semen Sinapis Albae 15-25, Flos Magnoliae 6-15, Fructus Xanthii 6-15, Fructus Gleditsiae Abnormalis 6-15, Radix Angelicae Dahuricae 8-12, Flos Caryophylli 2-8, Herba Ephedrae 2-8, Herba Menthae 2-8, Borneolum Syntheticum 2-8, Moschus 1-3.
The further crude drug amounts of components of the present invention is: Herba Asari 17-23, Radix Kansui 17-23, Semen Sinapis Albae 17-23, Flos Magnoliae 8-12, Fructus Xanthii 8-12, Fructus Gleditsiae Abnormalis 8-12, Radix Angelicae Dahuricae 8-12, Flos Caryophylli 4-6, Herba Ephedrae 4-6, Herba Menthae 4-6, Borneolum Syntheticum 4-6, Moschus 1-2.
The preferred crude drug amounts of components of the present invention is: Herba Asari 18-22, Radix Kansui 18-22, Semen Sinapis Albae 18-22, Flos Magnoliae 9-11, Fructus Xanthii 9-11, Fructus Gleditsiae Abnormalis 9-11, Radix Angelicae Dahuricae 9-11, Flos Caryophylli 4-5, Herba Ephedrae 5-6, Herba Menthae 4-6, Borneolum Syntheticum 5-6, Moschus 1-2.
The preparation method of the liniment for the treatment of of allergic rhinitis of the present invention is: described each crude drug is ground into powder, after described parts by weight mixing and stirring, reconciles into unguentum with an amount of Rhizoma Zingiberis Recens juice.Wherein, described Rhizoma Zingiberis Recens juice is to squeeze the juice with fresh ginger to make, and its consumption is for just being degree with described crude drug furnishing paste.
The using method of the liniment for the treatment of of allergic rhinitis of the present invention is: get the unguentum 6-10 gram of above-mentioned preparation, be coated in the plastic sheeting dressing, on the acupuncture points such as, the air door blind in big vertebra, cream of applying ointment or plaster, fei shu, shen shu, cement with medical proof fabric.General dog days, the coldest days of winter respectively use three times, once stick 2-6 hour, and 3 years is a course for the treatment of.
Also can further make disposable paster to above-mentioned unguentum, be placed in the airtight plastic bag for subsequent use.
For showing medicine of the present invention to the therapeutic effect of allergic rhinitis, select 47 routine Allergic Rhinitis to carry out clinical observation on the therapeutic effect.All cases all meet the diagnostic criteria of allergic rhinitis in State Administration of Traditional Chinese Medicine's " disease of tcm Standardization of diagnosis and curative effect ": 1) paroxysmal rhinocnesmus, continuous sneeze, nasal obstruction, the clear rare amount of nasal mucus mostly are cardinal symptom, with hyposmia, ophthalmic pruritus, the throat symptom such as itch.2) onset is rapid, and symptom generally continues several minutes to tens of minutes, and the intermission is without sneeze and nasal obstruction.3) often bring out because of the contact sensitizer or because of variations in temperature.4) the nasal mucosa edema is seen in the nasal cavity inspection, and is pale or congested, and concha nasalis swelling has more clear rare secretions during outbreak.5) lab testing, visible eosinophilia.
Above-mentioned 47 routine patients are divided into three groups immediately, and wherein treatment group 20 examples use medicine of the present invention to carry out acupoint application treatment, acupoint selection big vertebra, cream are blind, air door, fei shu, shen shu, annual dog days, the coldest days of winter respectively use three times, once stick 2-6 hour, and 3 years is a course for the treatment of.Contrast one group of 15 example, adopt the acupuncture therapy treatment, acupoint selection Yingxiang, the space between the eyebrows, broadcast TV programs by satellite, exceedingly high, connected valleys, tsu san li, fei shu, acupuncture every day 1 time, 10 times is 1 course for the treatment of, treats continuously 2 courses for the treatment of.Contrast two group of 12 example, adopt the pharmacotherapy treatment, take the BIYANKANG sheet, every day 3 times, each 4, three months is a course for the treatment of, takes continuously 2 courses for the treatment of.
Criterion of therapeutical effect foundation " disease of tcm Standardization of diagnosis and curative effect ": clinical recovery: the clinical symptoms complete obiterations such as rhinocnesmus, nasal obstruction, watery nasal discharge, sneeze, headache, concha nasalis is plump to disappear; Effectively: nasal obstruction, watery nasal discharge, sneeze disappear substantially, and other clinical symptoms and concha nasalis plumpness alleviate; Invalid: clinical symptoms and nose section check all without the improver.
Clinical therapeutic efficacy is carried out statistical analysis, and wherein in treatment group 20 examples, clinical recovery 15 examples account for 75%, and produce effects 5 examples account for 25%; Contrast in one group of 15 example, clinical recovery 8 examples account for 53.3%, and produce effects 5 examples account for 33.3%, and invalid 2 examples account for 13.3%.Contrast in two group of 12 example, clinical recovery 5 examples account for 41.7%, and produce effects 6 examples account for 50%, and invalid 1 example accounts for 8.3%.
Medical record is given an example: a * *, and the woman, 35 years old, on June 20th, 2007 was medical.Nasal obstruction repeatedly, sneeze, snivel 3 years, paroxysmal sneeze recurs, and flows a large amount of thin nasal discharge, with early morning, night for very.Once Western medicine diagnose was allergic rhinitis, used once hismanal 10mg over 3 years, and was oral, every day 1 time; Levocabastine spray nose, every day 2 times; Symptom is eased very soon, but is difficult to thorough healing.With turning acupuncture and moxibustion therapy, also can not thoroughly cure.Satisfy and come here medical, entering to paste the hot summer days medicine, after 07,08, the 09 year first day of the first period of the hot season, the second of the three ten-day periods of the hot season, the first day of the last period of the hot season and nine periods one nine, 29, blind, the SHENYU point of 3 years big vertebras of each one-time continuous of three nine-day periods after the winter solstice, air door, fei shu, cream sticks, the patient thoroughly fully recovers after 3 years, follows up a case by regular visits to half a year without recurrence.
The specific embodiment
Embodiment 1
Each crude drug is ground into powder, according to following weight mixing and stirring: Herba Asari 360g, Radix Kansui 400g, Semen Sinapis Albae 380g, Flos Magnoliae 200g, Fructus Xanthii 180g, Fructus Gleditsiae Abnormalis 200g, Radix Angelicae Dahuricae 220g, Flos Caryophylli 85g, Herba Ephedrae 100g, Herba Menthae 80g, Borneolum Syntheticum 120g, Moschus 30g, add the fresh Rhizoma Zingiberis Recens juice furnishing paste that squeezes of 2000g, it is for subsequent use to bottle.
Embodiment 2
Each crude drug is ground into powder, according to following weight mixing and stirring: Herba Asari 190g, Radix Kansui 230g, Semen Sinapis Albae 190g, Flos Magnoliae 90g, Fructus Xanthii 100g, Fructus Gleditsiae Abnormalis 90g, Radix Angelicae Dahuricae 100g, Flos Caryophylli 50g, Herba Ephedrae 60g, Herba Menthae 50g, Borneolum Syntheticum 60g, Moschus 14g, add the fresh Rhizoma Zingiberis Recens juice furnishing paste that squeezes of 1000g, it is for subsequent use to bottle.
Embodiment 3
Each crude drug is ground into powder, according to following weight mixing and stirring: Herba Asari 210g, Radix Kansui 200g, Semen Sinapis Albae 220g, Flos Magnoliae 100g, Fructus Xanthii 110g, Fructus Gleditsiae Abnormalis 110g, Radix Angelicae Dahuricae 100g, Flos Caryophylli 50g, Herba Ephedrae 50g, Herba Menthae 55g, Borneolum Syntheticum 50g, Moschus 16g, add the fresh Rhizoma Zingiberis Recens juice furnishing paste that squeezes of 2000g, it is for subsequent use to bottle.
Claims (5)
1. the liniment of a treatment of allergic rhinitis is characterized in that being made by the crude drug of following portions by weight: Herba Asari 15-25, Radix Kansui 15-25, Semen Sinapis Albae 15-25, Flos Magnoliae 6-15, Fructus Xanthii 6-15, Fructus Gleditsiae Abnormalis 6-15, Radix Angelicae Dahuricae 8-12, Flos Caryophylli 2-8, Herba Ephedrae 2-8, Herba Menthae 2-8, Borneolum Syntheticum 2-8, Moschus 1-3.
2. the liniment for the treatment of of allergic rhinitis according to claim 1 is characterized in that being made by the crude drug of following portions by weight: Herba Asari 17-23, Radix Kansui 17-23, Semen Sinapis Albae 17-23, Flos Magnoliae 8-12, Fructus Xanthii 8-12, Fructus Gleditsiae Abnormalis 8-12, Radix Angelicae Dahuricae 8-12, Flos Caryophylli 4-6, Herba Ephedrae 4-6, Herba Menthae 4-6, Borneolum Syntheticum 4-6, Moschus 1-2.
3. the liniment for the treatment of of allergic rhinitis according to claim 1 is characterized in that being made by the crude drug of following portions by weight: Herba Asari 18-22, Radix Kansui 18-22, Semen Sinapis Albae 18-22, Flos Magnoliae 9-11, Fructus Xanthii 9-11, Fructus Gleditsiae Abnormalis 9-11, Radix Angelicae Dahuricae 9-11, Flos Caryophylli 4-5, Herba Ephedrae 5-6, Herba Menthae 4-6, Borneolum Syntheticum 5-6, Moschus 1-2.
4. the preparation method of the liniment of claim 1,2 or 3 treatment of allergic rhinitis is characterized in that described each crude drug is ground into powder, after described parts by weight mixing and stirring, reconciles into unguentum with an amount of Rhizoma Zingiberis Recens juice.
5. the preparation method of the liniment for the treatment of of allergic rhinitis according to claim 4, the consumption that it is characterized in that described Rhizoma Zingiberis Recens juice is for just with described crude drug furnishing paste.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011102197580A CN102266393B (en) | 2011-08-03 | 2011-08-03 | External application medicament for treating allergic rhinitis and preparation method thereof |
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| CN2011102197580A CN102266393B (en) | 2011-08-03 | 2011-08-03 | External application medicament for treating allergic rhinitis and preparation method thereof |
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| CN102266393B true CN102266393B (en) | 2013-04-03 |
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251709B (en) * | 2013-05-27 | 2014-06-04 | 丁念善 | External medicine nose through paste for treating rhinitis and preparation method thereof |
| CN104107231A (en) * | 2014-07-24 | 2014-10-22 | 周冠旻 | Traditional Chinese medicinal composition for treating allergic rhinitis for oral administration and external application and preparation method of traditional Chinese medicinal composition |
| CN104491806A (en) * | 2014-12-21 | 2015-04-08 | 张景悦 | External traditional Chinese medicine for treating allergic rhinitis |
| CN104688984A (en) * | 2015-03-31 | 2015-06-10 | 杨发祥 | Ointment for treating anaphylactic rhinitis and preparation method thereof |
| CN104997908A (en) * | 2015-07-01 | 2015-10-28 | 南浦 | External ointment for treating rhinitis |
| CN105326923B (en) * | 2015-10-10 | 2019-04-02 | 浙江中医药大学 | A kind of fermentation rhinitis plaster |
| CN107375422A (en) * | 2017-08-11 | 2017-11-24 | 重庆市中医院 | Treatment part catarrh symptom liniment and preparation method thereof |
| CN108283708A (en) * | 2018-04-08 | 2018-07-17 | 陈康 | A kind of pharmaceutical composition and preparation method thereof for treating acute rhinitis and chronic and allergic rhinitis |
| CN109528997A (en) * | 2018-12-21 | 2019-03-29 | 贵州优可安生物科技有限公司 | A kind of sensible Chinese medicine composition of promoting the dispersing function of the lung |
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