CN104688984A - Ointment for treating anaphylactic rhinitis and preparation method thereof - Google Patents

Ointment for treating anaphylactic rhinitis and preparation method thereof Download PDF

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CN104688984A
CN104688984A CN201510145975.8A CN201510145975A CN104688984A CN 104688984 A CN104688984 A CN 104688984A CN 201510145975 A CN201510145975 A CN 201510145975A CN 104688984 A CN104688984 A CN 104688984A
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herba
fructus
ointment
mentholum
colophonium
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杨百志
王志强
付海柱
王卫军
杨发祥
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Abstract

The invention discloses an ointment for treating anaphylactic rhinitis. The ointment for treating anaphylactic rhinitis is composed of 20-40 g of small centipeda herbs, 20-60 g of fructus gleditsiae, 10-30 g of castor bean, 4-12 g of cutch, 4-12g of rosin, 4-12g of resina draconis, 5-15 g of pangolin, 5-15 g of pig nails, 2-4 g of calomel, 10-30 g of dahurian patrinia herbs, 10-30 g of berberis poiretii schneid, 10-30 g of honeysuckle, 10-30 g of fructus forsythiae, 10-30 g of polygonum cuspidatum, 10-30 g of nidus vespae, 10-60 g of ephedra, 15-45 g of asarum, 40-80 g of radix angelicae dahuricae, 40-80 g of flos magnoliae, 40-80 g of fructus xanthii, 5-15 g of calamus, 5-15 g of pericarpium papaveris, 5-15 g of borneol, 2-6 g of menthol, 0.2-0.6 g of chlortrimeton, 20-60 g of beewax and 950-2000 g of sesame oil.

Description

Ointment of a kind for the treatment of of allergic rhinitis and preparation method thereof
Technical field
The present invention relates to a kind of drug for treating rhinitis, specifically a kind of ointment and preparation method thereof for the treatment of of allergic rhinitis.
Background technology
At present, due to factors such as air pollutions, Allergic Rhinitis showed increased, though there are the medicine application such as Folium Crossostephii Chinensis capsule clinically, curative effect is unsatisfactory, and patient expects that the good medicine of a kind of curative effect comes out, and solves this difficult problem.
Summary of the invention
The problem to be solved in the present invention is for above problem, provides ointment of a kind for the treatment of of allergic rhinitis and preparation method thereof, and this ointment can alleviate the symptoms such as nasal obstruction, watery nasal discharge fast, Normalization rule, can clinical cure allergic rhinitis, and safety, without any side effects.
For solving the problem, the technical solution adopted in the present invention is:
A kind of ointment for the treatment of of allergic rhinitis, it is characterized in that: be made up of crude drug: Herba Centipedae 20-40g, Fructus Gleditsiae Abnormalis 20-60g, Semen Ricini 10-30g, catechu 4-12g, Colophonium 4-12g, Sanguis Draxonis 4-12g, Squama Manis 5-15g, Unguis Sus domestica 5-15g, Calomelas 2-4g, Herba Patriniae 10-30g, Radix Berberidis 10-30g, Flos Lonicerae 10-30g, Fructus Forsythiae 10-30g, Rhizoma Polygoni Cuspidati 10-30g, Nidus Vespae 10-30g, Herba Ephedrae 10-60g, Herba Asari 15-45g, Radix Angelicae Dahuricae 40-80g, Flos Magnoliae 40-80g, Fructus Xanthii 40-80g, Rhizoma Acori Graminei 5-15g, Pericarpium Papaveris 5-15g, Borneolum Syntheticum 5-15g, Mentholum 2-6g, the quick 0.2-0.6g of Piao Er, Cera Flava 20-60g, Oleum sesami 950-2000g is prepared from.
It is below the further improvement to technique scheme
An ointment for treatment of allergic rhinitis, be made up of the crude drug of following weight:
Herba Centipedae 20g, Fructus Gleditsiae Abnormalis 20g, Semen Ricini 10g, catechu 4g, Colophonium 4g, Sanguis Draxonis 4g, Squama Manis 5g, Unguis Sus domestica 5g, Calomelas 2g, Herba Patriniae 10g, Radix Berberidis 10g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Rhizoma Polygoni Cuspidati 10g, Nidus Vespae 10g, Herba Ephedrae 20g, Herba Asari 15g, Radix Angelicae Dahuricae 40g, Flos Magnoliae 40g, Fructus Xanthii 40g, Rhizoma Acori Graminei 5g, Pericarpium Papaveris 5g, Borneolum Syntheticum 5g, Mentholum 2g, chlorphenamine 0.2g, Cera Flava 20g, Oleum sesami 950g are prepared from.
Below the further improvement to technique scheme:
Herba Centipedae 40g, Fructus Gleditsiae Abnormalis 60g, Semen Ricini 30g, catechu 12g, Colophonium 12g, Sanguis Draxonis 12g, Squama Manis 15g, Unguis Sus domestica 15g, Calomelas 4g, Herba Patriniae 30g, Radix Berberidis 30g, Flos Lonicerae 30g, Fructus Forsythiae 30g, Rhizoma Polygoni Cuspidati 30g, Nidus Vespae 30g, Herba Ephedrae 60g, Herba Asari 45g, Radix Angelicae Dahuricae 80g, Flos Magnoliae 80g, Fructus Xanthii 80g, Rhizoma Acori Graminei 15g, Pericarpium Papaveris 15g, Borneolum Syntheticum 15g, Mentholum 6g, chlorphenamine 0.6g, Cera Flava 60g, Oleum sesami 2000g are prepared from.
Below the further improvement to technique scheme:
Herba Centipedae 30g, Fructus Gleditsiae Abnormalis 40g, Semen Ricini 15g, catechu 8g, Colophonium 8g, Sanguis Draxonis 8g, Squama Manis 10g, Unguis Sus domestica 10g, Calomelas 3g, Herba Patriniae 20g, Radix Berberidis 20g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Rhizoma Polygoni Cuspidati 23g, Nidus Vespae 16g, Herba Ephedrae 40g, Herba Asari 30g, Radix Angelicae Dahuricae 60g, Flos Magnoliae 60g, Fructus Xanthii 60g, Rhizoma Acori Graminei 10g, Pericarpium Papaveris 10g, Borneolum Syntheticum 10g, Mentholum 4g, chlorphenamine 0.4g, Cera Flava 40g, Oleum sesami 1450g are prepared from.
Symptom not outer nasal obstruction, watery nasal discharge, the distending pain of rhinitis, the not outer ailment said due to cold or exposure of the pathology that gets to the bottom of sb.'s illness invade lung, damp is detained, lung key is inaccessible, modern medicine thinks relevant with inflammation and allergy, said medicine is roughly divided into three groups, Herba Patriniae, Radix Berberidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Fructus Forsythiae, Nidus Vespae are one group, and clearing away heat and discharging pus, has antiinflammation;
Semen Ricini, catechu, Colophonium, Sanguis Draxonis and Calomelas add Squama Manis, Unguis Sus domestica is one group, promoting blood circulation to restore menstrual flow, evacuation of pus of drawing out pus by applying a plaster to the affected part, granulation promoting pain relieving;
Herba Centipedae, Fructus Gleditsiae Abnormalis, Herba Ephedrae, Herba Asari, Fructus Xanthii, the Radix Angelicae Dahuricae, Flos Magnoliae are one group, specially enter lung meridian, expelling pathogenic wind and restoring the functions of orifices in face, eliminating dampness and expelling toxin, for treating the key agents of rhinitis;
Pericarpium Papaveris, Mentholum act on local nerve tip, have anesthetic action, remove local discomfort,
Rhizoma Acori Graminei, Borneolum Syntheticum and Herba Ephedrae are share, and enhance and shrink nasal cavity blood vessel, antiallergic, the function of clearing the nasal passage,
Add that Western medicine chlorphenamine is particularly suitable to allergic rhinitis, said medicine Chinese and Western combines, and the mutual reinforcement between mutual-assistance is use, expelling wind and removing dampness, heat-clearing and toxic substances removing, antiinflammatory antiallergic, to the releasing cause of disease, and relief of symptoms, successful.
A kind of preparation method of ointment for the treatment of of allergic rhinitis:
(1) each ingredient is weighed, single bag;
(2) by catechu, Colophonium, Sanguis Draxonis, Calomelas, Borneolum Syntheticum, Mentholum, chlorphenamine porphyrize list bag;
(3) Fructus Xanthii hammer is smashed every paper; Fructus Gleditsiae Abnormalis hammering is broken, each single bag
(4) Oleum sesami is poured in pot heat, then put into Semen Ricini successively, Rhizoma Polygoni Cuspidati, Fructus Xanthii, Fructus Gleditsiae Abnormalis, Flos Magnoliae, Nidus Vespae, Squama Manis, Unguis Sus domestica, Flos Lonicerae, Fructus Forsythiae, Herba Patriniae, the Radix Angelicae Dahuricae, Herba Asari, Herba Ephedrae, Herba Centipedae, Rhizoma Acori Graminei, Pericarpium Papaveris, Radix Berberidis slow fire fries, said medicine is exploded black after pull out, filter;
(5) the medicine oil after filtering, put into Colophonium Cera Flava and melt, put into the medicated powder that step 2 is obtained after slightly cool, wherein Borneolum Syntheticum, Mentholum is finally put into, stir, dress bottle is for subsequent use.
During use, dip in ointment plug in nasal cavity by swab stick, retain 40 minutes, every day 2-3 time, the present invention has good efficacy to allergic rhinitis, can remove nasal obstruction, rhinorrhea symptom faster, without any side effects, to having better effect of school age population.
Detailed description of the invention
Embodiment 1, an ointment for treatment of allergic rhinitis, is made up of following weight crude drug: Herba Centipedae 20g, Fructus Gleditsiae Abnormalis 20g, Semen Ricini 10g, catechu 4g, Colophonium 4g, Sanguis Draxonis 4g, Squama Manis 5g, Unguis Sus domestica 5g, Calomelas 2g, Herba Patriniae 10g, Radix Berberidis 10g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Rhizoma Polygoni Cuspidati 10g, Nidus Vespae 10g, Herba Ephedrae 20g, Herba Asari 15g, Radix Angelicae Dahuricae 40g, Flos Magnoliae 40g, Fructus Xanthii 40g, Rhizoma Acori Graminei 5g, Pericarpium Papaveris 5g, Borneolum Syntheticum 5g, Mentholum 2g, chlorphenamine 0.2g, Cera Flava 20g, Oleum sesami 950g are prepared from.
A kind of preparation method of ointment for the treatment of of allergic rhinitis:
(1) each ingredient is weighed, single bag;
(2) by catechu, Colophonium, Sanguis Draxonis, Calomelas, Borneolum Syntheticum, Mentholum, chlorphenamine porphyrize list bag;
(3) Fructus Xanthii hammer is smashed every paper; Fructus Gleditsiae Abnormalis hammering is broken, each single bag
(4) Oleum sesami is poured in pot heat, then put into Semen Ricini successively, Rhizoma Polygoni Cuspidati, Fructus Xanthii, Fructus Gleditsiae Abnormalis, Flos Magnoliae, Nidus Vespae, Squama Manis, Unguis Sus domestica, Flos Lonicerae, Fructus Forsythiae, Herba Patriniae, the Radix Angelicae Dahuricae, Herba Asari, Herba Ephedrae, Herba Centipedae, Rhizoma Acori Graminei, Pericarpium Papaveris, Radix Berberidis slow fire fries, said medicine is exploded black after pull out, filter;
(5) the medicine oil after filtering, put into Colophonium, Cera Flava melts, put into the medicated powder that step 2 is obtained after slightly cool, wherein Borneolum Syntheticum, Mentholum is finally put into, stir, dress bottle is for subsequent use.
Embodiment 2, an ointment for treatment of allergic rhinitis, is made up of following weight crude drug: Herba Centipedae 40g, Fructus Gleditsiae Abnormalis 60g, Semen Ricini 30g, catechu 12g, Colophonium 12g, Sanguis Draxonis 12g, Squama Manis 15g, Unguis Sus domestica 15g, Calomelas 4g, Herba Patriniae 30g, Radix Berberidis 30g, Flos Lonicerae 30g, Fructus Forsythiae 30g, Rhizoma Polygoni Cuspidati 30g, Nidus Vespae 30g, Herba Ephedrae 60g, Herba Asari 45g, Radix Angelicae Dahuricae 80g, Flos Magnoliae 80g, Fructus Xanthii 80g, Rhizoma Acori Graminei 15g, Pericarpium Papaveris 15g, Borneolum Syntheticum 15g, Mentholum 6g, chlorphenamine 0.6g, Cera Flava 60g, Oleum sesami 2000g are prepared from.
A kind of preparation method of ointment for the treatment of of allergic rhinitis:
(1) each ingredient is weighed, single bag;
(2) by catechu, Colophonium, Sanguis Draxonis, Calomelas, Borneolum Syntheticum, Mentholum, chlorphenamine porphyrize list bag;
(3) Fructus Xanthii hammer is smashed every paper; Fructus Gleditsiae Abnormalis hammering is broken, each single bag
(4) Oleum sesami is poured in pot heat, then put into Semen Ricini successively, Rhizoma Polygoni Cuspidati, Fructus Xanthii, Fructus Gleditsiae Abnormalis, Flos Magnoliae, Nidus Vespae, Squama Manis, Unguis Sus domestica, Flos Lonicerae, Fructus Forsythiae, Herba Patriniae, the Radix Angelicae Dahuricae, Herba Asari, Herba Ephedrae, Herba Centipedae, Rhizoma Acori Graminei, Pericarpium Papaveris, Radix Berberidis slow fire fries, said medicine is exploded black after pull out, filter;
(5) the medicine oil after filtering, put into Colophonium, Cera Flava melts, put into the medicated powder that step 2 is obtained after slightly cool, wherein Borneolum Syntheticum, Mentholum is finally put into, stir, dress bottle is for subsequent use.
Embodiment 3, an ointment for treatment of allergic rhinitis, is made up of following weight crude drug: Herba Centipedae 30g, Fructus Gleditsiae Abnormalis 40g, Semen Ricini 15g, catechu 8g, Colophonium 8g, Sanguis Draxonis 8g, Squama Manis 10g, Unguis Sus domestica 10g, Calomelas 3g, Herba Patriniae 20g, Radix Berberidis 20g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Rhizoma Polygoni Cuspidati 23g, Nidus Vespae 16g, Herba Ephedrae 40g, Herba Asari 30g, Radix Angelicae Dahuricae 60g, Flos Magnoliae 60g, Fructus Xanthii 60g, Rhizoma Acori Graminei 10g, Pericarpium Papaveris 10g, Borneolum Syntheticum 10g, Mentholum 4g, chlorphenamine 0.4g, Cera Flava 40g, Oleum sesami 1450g are prepared from.
A kind of preparation method of ointment for the treatment of of allergic rhinitis:
(1) each ingredient is weighed, single bag;
(2) by catechu, Colophonium, Sanguis Draxonis, Calomelas, Borneolum Syntheticum, Mentholum, chlorphenamine porphyrize list bag;
(3) Fructus Xanthii hammer is smashed every paper; Fructus Gleditsiae Abnormalis hammering is broken, each single bag
(4) Oleum sesami is poured in pot heat, then put into Semen Ricini successively, Rhizoma Polygoni Cuspidati, Fructus Xanthii, Fructus Gleditsiae Abnormalis, Flos Magnoliae, Nidus Vespae, Squama Manis, Unguis Sus domestica, Flos Lonicerae, Fructus Forsythiae, Herba Patriniae, the Radix Angelicae Dahuricae, Herba Asari, Herba Ephedrae, Herba Centipedae, Rhizoma Acori Graminei, Pericarpium Papaveris, Radix Berberidis slow fire fries, said medicine is exploded black after pull out, filter;
(5) the medicine oil after filtering, put into Colophonium, Cera Flava melts, put into the medicated powder that step 2 is obtained after slightly cool, wherein Borneolum Syntheticum, Mentholum is finally put into, stir, dress bottle is for subsequent use.
In the 430 routine Allergic Rhinitis that my institute accepts for medical treatment in recent years, 100 examples use the ointment in embodiment 1,100 examples use the ointment in embodiment 2,130 examples use the ointment in embodiment 3, and 100 examples use Folium Crossostephii Chinensis capsule (Shandong Buchang Pharmaceutical Co., Ltd., the accurate word Z19991040 of traditional Chinese medicines), as a control group, each group of pathology is at age, sex, symptom weight, and course of disease length, has comparability.
The oral Folium Crossostephii Chinensis capsule of matched group, each three, every day three times, treatments period, withdraws other drug.
Treatment standard comprises:
Effective: to yawn, nasal obstruction, watery nasal discharge partial symptoms alleviates;
Effective; Above-mentioned symptom major part disappears;
Clinical cure: above-mentioned symptom disappears substantially, from beginning medication meter, Estimating curative effect after two months, therapeutic effect sees the following form.
   
By above-mentioned contrast, can find out that the clinical cure case of medicine of the present invention is significantly better than matched group, matched group 19 example is cured, and cure rate is 19%, prove that ointment of the present invention is to treatment of allergic rhinitis, there is significant curative effect, in addition in treatment group, the best results of embodiment 3, effective percentage 100%, obvious effective rate 93%, the number of cases of clinical cure is 111 examples, and cure rate reaches 85%.
We are to the patient of the ointment used in the embodiment of the present invention 3, through all paying a return visit, clinical cure case had 6 example recurrences in 1 year, but symptom also obviously alleviates, prove that ointment of the present invention has good late result, relapse rate is only 0.05%, and well-known allergic rhinitis is very easy to recurrence, and adopts the medicine in the embodiment of the present invention 3 to carry out the treatment relapse rate of 1 year to be only 0.05%.

Claims (5)

1. the ointment of a treatment of allergic rhinitis, it is characterized in that: be made up of crude drug: Herba Centipedae 20-40g, Fructus Gleditsiae Abnormalis 20-60g, Semen Ricini 10-30g, catechu 4-12g, Colophonium 4-12g, Sanguis Draxonis 4-12g, Squama Manis 5-15g, Unguis Sus domestica 5-15g, Calomelas 2-4g, Herba Patriniae 10-30g, Radix Berberidis 10-30g, Flos Lonicerae 10-30g, Fructus Forsythiae 10-30g, Rhizoma Polygoni Cuspidati 10-30g, Nidus Vespae 10-30g, Herba Ephedrae 10-60g, Herba Asari 15-45g, Radix Angelicae Dahuricae 40-80g, Flos Magnoliae 40-80g, Fructus Xanthii 40-80g, Rhizoma Acori Graminei 5-15g, Pericarpium Papaveris 5-15g, Borneolum Syntheticum 5-15g, Mentholum 2-6g, the quick 0.2-0.6g of Piao Er, Cera Flava 20-60g, Oleum sesami 950-2000g is prepared from.
2. the ointment of a kind for the treatment of of allergic rhinitis as claimed in claim 1, it is characterized in that: be made up of the crude drug of following weight, it is characterized in that: Herba Centipedae 20g, Fructus Gleditsiae Abnormalis 20g, Semen Ricini 10g, catechu 4g, Colophonium 4g, Sanguis Draxonis 4g, Squama Manis 5g, Unguis Sus domestica 5g, Calomelas 2g, Herba Patriniae 10g, Radix Berberidis 10g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Rhizoma Polygoni Cuspidati 10g, Nidus Vespae 10g, Herba Ephedrae 20g, Herba Asari 15g, Radix Angelicae Dahuricae 40g, Flos Magnoliae 40g, Fructus Xanthii 40g, Rhizoma Acori Graminei 5g, Pericarpium Papaveris 5g, Borneolum Syntheticum 5g, Mentholum 2g, the quick 0.2g of Piao Er, Cera Flava 20g, Oleum sesami 950g is prepared from.
3. the ointment of a kind for the treatment of of allergic rhinitis as claimed in claim 1, is characterized in that: Herba Centipedae 40g, Fructus Gleditsiae Abnormalis 60g, Semen Ricini 30g, catechu 12g, Colophonium 12g, Sanguis Draxonis 12g, Squama Manis 15g, Unguis Sus domestica 15g, Calomelas 4g, Herba Patriniae 30g, Radix Berberidis 30g, Flos Lonicerae 30g, Fructus Forsythiae 30g, Rhizoma Polygoni Cuspidati 30g, Nidus Vespae 30g, Herba Ephedrae 60g, Herba Asari 45g, Radix Angelicae Dahuricae 80g, Flos Magnoliae 80g, Fructus Xanthii 80g, Rhizoma Acori Graminei 15g, Pericarpium Papaveris 15g, Borneolum Syntheticum 15g, the quick 0.6g of Mentholum 6g, Piao Er, Cera Flava 60g, Oleum sesami 2000g are prepared from.
4. the ointment of a kind for the treatment of of allergic rhinitis as claimed in claim 1, is characterized in that: Herba Centipedae 30g, Fructus Gleditsiae Abnormalis 40g, Semen Ricini 15g, catechu 8g, Colophonium 8g, Sanguis Draxonis 8g, Squama Manis 10g, Unguis Sus domestica 10g, Calomelas 3g, Herba Patriniae 20g, Radix Berberidis 20g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Rhizoma Polygoni Cuspidati 23g, Nidus Vespae 16g, Herba Ephedrae 40g, Herba Asari 30g, Radix Angelicae Dahuricae 60g, Flos Magnoliae 60g, Fructus Xanthii 60g, Rhizoma Acori Graminei 10g, Pericarpium Papaveris 10g, Borneolum Syntheticum 10g, the quick 0.4g of Mentholum 4g, Piao Er, Cera Flava 40g, Oleum sesami 1450g are prepared from.
5., as the preparation method of the ointment of a kind for the treatment of of allergic rhinitis of claim 1-4 as described in one of them, it is characterized in that:
Weigh each ingredient, single bag;
By catechu, Colophonium, Sanguis Draxonis, Calomelas, Borneolum Syntheticum, Mentholum, Piao Er quick porphyrize list bag;
Fructus Xanthii hammer is smashed every paper; Fructus Gleditsiae Abnormalis hammering is broken, each single bag
Oleum sesami is imported in pot and heats, then put into Semen Ricini successively, Rhizoma Polygoni Cuspidati, Fructus Xanthii, Fructus Gleditsiae Abnormalis, Flos Magnoliae, Nidus Vespae, Squama Manis, Unguis Sus domestica, Flos Lonicerae, Fructus Forsythiae, Herba Patriniae, the Radix Angelicae Dahuricae, Herba Asari, Herba Ephedrae, Herba Centipedae, Rhizoma Acori Graminei, Pericarpium Papaveris, Radix Berberidis slow fire fries, said medicine is exploded black after pull out, filter;
Medicine oil after filtration, put into Colophonium Cera Flava and melt, put into the medicated powder that step 2 is obtained after slightly cool, wherein Borneolum Syntheticum, Mentholum is finally put into, stir, dress bottle is for subsequent use.
CN201510145975.8A 2015-03-31 2015-03-31 Ointment for treating anaphylactic rhinitis and preparation method thereof Pending CN104688984A (en)

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Publication number Priority date Publication date Assignee Title
CN104971202A (en) * 2015-07-23 2015-10-14 王兴通 Externally used ointment for treating scab and preparation method
CN104997908A (en) * 2015-07-01 2015-10-28 南浦 External ointment for treating rhinitis
CN105326924A (en) * 2015-10-28 2016-02-17 周胜光 Allergy-removal rhinitis cream
CN108542944A (en) * 2018-07-12 2018-09-18 合肥七小俊生物科技有限公司 A kind of adult's allergic rhinitis cream and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104997908A (en) * 2015-07-01 2015-10-28 南浦 External ointment for treating rhinitis
CN104971202A (en) * 2015-07-23 2015-10-14 王兴通 Externally used ointment for treating scab and preparation method
CN105326924A (en) * 2015-10-28 2016-02-17 周胜光 Allergy-removal rhinitis cream
CN108542944A (en) * 2018-07-12 2018-09-18 合肥七小俊生物科技有限公司 A kind of adult's allergic rhinitis cream and preparation method thereof

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