CN104043008A - External traditional Chinese medicinal composition for treating myofascitis and preparation method thereof - Google Patents
External traditional Chinese medicinal composition for treating myofascitis and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of traditional Chinese medicines, and discloses an external traditional Chinese medicinal composition for treating myofascitis. The traditional Chinese medicinal composition is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 10-30 parts of radix clematidis, 5-15 parts of lycopodium clavatum, 5-15 parts of kadsura root-bark, 5-15 parts of cortex erythrinae variegatae, 5-15 parts of Ligusticum wallichii, 3-10 parts of pseudo-ginseng, 3-10 parts of cortex dictamni, 3-10 parts of resurrection lily rhizome and 2-5 parts of turpentine. The invention also provides a preparation method of the traditional Chinese medicinal composition, which comprises the following steps: decocting and extracting the traditional Chinese medicinal raw materials: radix clematidis, lycopodium clavatum, kadsura root-bark, cortex erythrinae variegatae, Ligusticum wallichii, pseudo-ginseng, cortex dictamni and resurrection lily rhizome, adding the turpentine, and uniformly mixing to obtain the active component of the traditional Chinese medicinal composition. On the basis of basic pathogenesis of myofascitis, which is mainly reflected on cold-damp stagnation in ribs, as well as qi-stagnation and blood stasis, the traditional Chinese medicinal composition can be used for effectively treating myofascitis by adopting a basic method of dispelling coldness and eliminating dampness, activating blood circulation to remove stasis, soothing tendons and dredging collaterals.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of external medicine composition that is used for the treatment of myofascitis and preparation method thereof.
Background technology
Myofascitis is common clinical, frequently-occurring disease, and Epidemiological study shows that myofascitis is 9.57% in the prevalence of China, along with this sick sickness rate of transformation of people's daily life style presents the trend raising year by year.Myofascitis main clinic symptoms is pain and dysfunction, its cause of disease is comparatively complicated, think at present main relevant with the factor such as strain, wound, its main pathology shows as musculofascial aseptic inflammation, and severe patient even there will be muscular fasciae adhesion and fiber pathological changes.Myofascitis belongs to Chinese medicine " arthromyodynia " category, and " Plain Questions numbness opinion " thought and " wet three gas of wind and cold are mixed extremely, combined into numbness " referred to that various paathogenic factors cause obstruction of meridians and collaterals obstructed, stagnation of QI and blood may bring about pain.Have researcher to think by long-term large sample clinical research: grain strains, loses in replenishing vital QI with drugs of warm nature is the basic pathogenesis of myofascitis, the solidifying muscle of cold-damp is that main holding concurrently is the basic pattern of syndrome of myofascitis with qi depression to blood stasis, and warm muscle dredging collateral is the basic therapy of myofascitis.Think that about the treatment modern medicine of myofascitis nonsteroidal (NSAIDS) medicine is effective to myofascitis, but because the side effect such as its significant gastrointestinal tract are restricted its use.And be one of Main Means for the treatment of myofascitis at China's Chinese medicine, especially external application Chinese medicine is because it is evident in efficacy and toxic and side effects receives increasing concern compared with little.
Summary of the invention
The object of the present invention is to provide a kind of external medicine composition for the treatment of myofascitis, to reach the therapeutical effect of dispelling cold and removing dampness, blood circulation promoting and blood stasis dispelling, channels sootheing and network vessel quickening.
Another object of the present invention is to the preparation method of the external medicine composition that above-mentioned treatment myofascitis is provided.
For solving the problems of the technologies described above, the external medicine composition for the treatment of myofascitis provided by the present invention, is made up of the raw material of Chinese medicine of following weight portion: 10～30 parts of Radix Clematidis, 5～15 parts of Herba Lycopodiis, 5～15 parts of Cortex cercis chinensiss, 5～15 parts of Cortex erythrinaes, 5～15 parts of Rhizoma Chuanxiongs, 3～10 parts of Radix Notoginseng, 3～10 parts of Cortex Dictamni, 3～10 parts of Rhizoma Kaempferiae, 2～5 parts of Oleum Terebinthinaes.
The external medicine composition for the treatment of myofascitis involved in the present invention, being based on the solidifying muscle of myofascitis cold-damp is main holding concurrently with the basic pathogenesis of qi depression to blood stasis, with dispelling cold and removing dampness, promoting blood circulation to remove obstruction in the collateral is basic therapy, treats safely and effectively myofascitis.
Preferably, the external medicine composition for the treatment of myofascitis of the present invention, is made up of the raw material of Chinese medicine of following weight portion: 20 parts of Radix Clematidis, 10 parts of Herba Lycopodiis, 10 parts of Cortex cercis chinensiss, 10 parts of Cortex erythrinaes, 10 parts of Rhizoma Chuanxiongs, 5 parts of Radix Notoginseng, 6 parts of Cortex Dictamni, 6 parts of Rhizoma Kaempferiae, 3 parts of Oleum Terebinthinaes.
The external medicine composition for the treatment of myofascitis of the present invention, made by Radix Clematidis, Herba Lycopodii, Cortex cercis chinensis, Cortex erythrinae, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Dictamni, Rhizoma Kaempferiae, Oleum Terebinthinae nine taste raw material of Chinese medicine, in side, Radix Clematidis is monarch drug, it is pungent, salty, and temperature is returned urinary bladder channel, energy expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, the twelve channels and collaterals that can pass through, is the key medicine for the treatment of rheumatic arthralgia; The micro-hardship of Herba Lycopodii, pungent, temperature, returns liver,spleen,kidney warp, energy expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Cortex cercis chinensis hardship, flat, return liver, spleen channel, energy promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.Cortex erythrinae is pungent, bitter, flat, returns liver, stomach, kidney channel, energy expelling wind and removing dampness, channels sootheing and network vessel quickening.Rhizoma Chuanxiong is pungent, and temperature is returned liver, gallbladder, pericardium channel, energy blood-activating and qi-promoting, and wind-expelling pain-stopping, above-mentioned four medicines are assisted effect of monarch drug performance expelling wind and removing dampness altogether for ministerial drug.Sweet, the micro-hardship of Radix Notoginseng, temperature, returns liver, stomach warp, can stop blooding by dissipating blood stasis, subduing swelling and relieving pain.Cortex Dictamni hardship, cold.Return spleen, stomach, urinary bladder channel, heat clearing and damp drying, the removing toxic substances of dispeling the wind.Rhizoma Kaempferiae is pungent, and temperature is returned stomach warp, energy circulation of qi promoting warming middle-JIAO, pain relieving.Above-mentioned three medicines are effect of adjuvant drug performance blood-activating and qi-promoting pain relieving altogether, and Cortex Dictamni is cold in nature simultaneously can restrict again the property that all medicines are warm; Oleum Terebinthinae is for making medicine, and local use can be brought into play the effect of promoting blood circulation and stopping pain, and again can coordinating the actions of various ingredients in a prescription external.
The present invention also provides the preparation method of the external medicine composition of above-mentioned treatment myofascitis, comprises following steps:
(1) take 10～30 parts of raw material of Chinese medicine Radix Clematidis, 5～15 parts of Herba Lycopodiis, 5～15 parts of Cortex cercis chinensiss, 5～15 parts of Cortex erythrinaes, 5～15 parts of Rhizoma Chuanxiongs, 3～10 parts of Radix Notoginseng, 3～10 parts of Cortex Dictamni, 3～10 parts of Rhizoma Kaempferiae according to following weight portion proportioning, carry out water boiling and extraction;
(2) in the extracting solution obtaining in above-mentioned water boiling and extraction, add the Oleum Terebinthinae of 2～5 parts of weight portions, mix homogeneously, obtains the active component of external medicine composition of the present invention.
The water boiling and extraction step of above-mentioned preparation method is: each raw material of Chinese medicine is put into decocting medicine pot, and 3～7 times of volumes that add water, intense fire boils 15～25 minutes.
The preparation method of the external medicine composition for the treatment of myofascitis provided by the present invention, further comprise following steps: on the basis of active component obtained above, further add pharmaceutically acceptable adjuvant, with conventional method of Chinese medicinal, be prepared into the regular dosage form of external medicine composition of the present invention.
Specifically, the external medicine composition for the treatment of myofascitis of the present invention, can further be prepared into the external preparation such as cataplasma, gel, liniment, ointment, ointment, spray, tincture, outer lotion.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearer, will be explained in detail the embodiments of the present invention below.But, persons of ordinary skill in the art may appreciate that in the each embodiment of the present invention, in order to make reader understand the application better, many ins and outs are proposed.But, even without these ins and outs and the many variations based on following embodiment and amendment, also can realize the each claim of the application technical scheme required for protection.
Below first further set forth the preparation method of the external medicine composition for the treatment of myofascitis of the present invention by Preparation Example.
The damp and hot application of embodiment 1
Take following raw materials according: Radix Clematidis 20g, Herba Lycopodii 10g, Cortex cercis chinensis 10g, Cortex erythrinae 10g, Rhizoma Chuanxiong 10g, Radix Notoginseng 5g, Cortex Dictamni 6g, Rhizoma Kaempferiae 6g, put into the decocting medicine pot 2000ml that adds water, boil 20 minutes with intense fire, medicine is decocted rear extracting juice and is added Oleum Terebinthinae 3g, obtains the damp and hot application that Chinese medicine composition of the present invention is used for the treatment of myofascitis.
Embodiment 2 cataplasmas
Prescription composition:
Radix Clematidis 20g, Herba Lycopodii 10g, Cortex cercis chinensis 10g, Cortex erythrinae 10g, Rhizoma Chuanxiong 10g, Radix Notoginseng 5g, Cortex Dictamni 6g, Rhizoma Kaempferiae 6g, Oleum Terebinthinae 3g
Preparation method:
By above-mentioned recipe quantity Radix Clematidis, Herba Lycopodii, Cortex cercis chinensis, Cortex erythrinae, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Dictamni, Rhizoma Kaempferiae, the 3 times of volumes that add water, intense fire boils 15 minutes, after water boiling and extraction, obtain mixed medicinal liquid, add appropriate PVPK90 to carry out swelling spending the night, make abundant dissolving; Separately get appropriate dihydroxyaluminum aminoacetate and be scattered in glycerol, form suspension; Above-mentioned medicinal liquid, Oleum Terebinthinae are added in the glycerol suspension containing dihydroxyaluminum aminoacetate, and mix homogeneously, with anti-stick lid lining form covering, cuts into pieces, packs respectively, to obtain final product.
Embodiment 3 gels
Prescription composition:
Radix Clematidis 10g, Herba Lycopodii 5g, Cortex cercis chinensis 6g, Cortex erythrinae 6g, Rhizoma Chuanxiong 5g, Radix Notoginseng 4g, Cortex Dictamni 3g, Rhizoma Kaempferiae 3g, Oleum Terebinthinae 2g
Preparation method:
(1) by above-mentioned recipe quantity Radix Clematidis, Herba Lycopodii, Cortex cercis chinensis, Cortex erythrinae, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Dictamni, Rhizoma Kaempferiae, the 5 times of volumes that add water, intense fire boils 20 minutes, after water boiling and extraction, obtains mixed medicinal liquid; (2) get appropriate Carbomer-940 and be evenly spread in appropriate distilled water, placing spends the night makes it fully swelling; (3), after the Oleum Terebinthinae, ethyl hydroxybenzoate of separately getting above-mentioned recipe quantity dissolves, add propylene glycol, tween 80, mix homogeneously.Under stirring, the material mix homogeneously that (1), (2), (3) step are obtained, stirs, and to obtain final product.
Embodiment 4 liniments
Prescription composition:
Radix Clematidis 30g, Herba Lycopodii 13g, Cortex cercis chinensis 15g, Cortex erythrinae 15g, Rhizoma Chuanxiong 13g, Radix Notoginseng 10g, Cortex Dictamni 10g, Rhizoma Kaempferiae 9g, Oleum Terebinthinae 5g
Preparation method:
(1) by above-mentioned recipe quantity Radix Clematidis, Herba Lycopodii, Cortex cercis chinensis, Cortex erythrinae, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Dictamni, Rhizoma Kaempferiae, the 7 times of volumes that add water, intense fire boils 25 minutes, after water boiling and extraction, obtains mixed medicinal liquid; (2) after the Oleum Terebinthinae of getting above-mentioned recipe quantity adds appropriate amount of ethanol and is stirred to dissolve, add 50% ethanol 100ml, mix, add the admixing medical solutions obtaining in (1), mix, adding 50% ethanol to total amount is 250ml, mixes, leave standstill, filter, to obtain final product.
Embodiment 5 ointments
Prescription composition:
Radix Clematidis 15g, Herba Lycopodii 8g, Cortex cercis chinensis 9g, Cortex erythrinae 8g, Rhizoma Chuanxiong 7g, Radix Notoginseng 5g, Cortex Dictamni 7g, Rhizoma Kaempferiae 5g, Oleum Terebinthinae 3g
Preparation technology:
(1) by above-mentioned recipe quantity Radix Clematidis, Herba Lycopodii, Cortex cercis chinensis, Cortex erythrinae, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Dictamni, Rhizoma Kaempferiae, 4 times of volumes add water, intense fire boils 20 minutes, after water boiling and extraction, obtain mixed medicinal liquid, add appropriate sodium lauryl sulphate, propylene glycol, ethyl hydroxybenzoate, distilled water, be heated to 70-80 DEG C, obtain water; (2) get stearyl alcohol, white vaseline melts in water-bath, adds the Oleum Terebinthinae of above-mentioned recipe quantity, stirs, and is heated to 70-80 DEG C, obtains oil phase; (3) water is added in synthermal oil phase, be stirred to condensation, obtain ointment.
Embodiment 6 sprays
Prescription composition:
Radix Clematidis 25g, Herba Lycopodii 13g, Cortex cercis chinensis 12g, Cortex erythrinae 12g, Rhizoma Chuanxiong 14g, Radix Notoginseng 8g, Cortex Dictamni 7g, Rhizoma Kaempferiae 8g, Oleum Terebinthinae 4g
Preparation technology:
By above-mentioned recipe quantity Radix Clematidis, Herba Lycopodii, Cortex cercis chinensis, Cortex erythrinae, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Dictamni, Rhizoma Kaempferiae, 6 times of volumes add water, intense fire boils 25 minutes, after water boiling and extraction, obtains mixed medicinal liquid, filter, get filtrate, add Oleum Terebinthinae, appropriate ethyl hydroxybenzoate, mix homogeneously, be packed in spray device the appropriate N of filling simultaneously
2, to obtain final product.
Further set forth externally-applied medicinal composition of the present invention at the beneficial effect aspect treatment myofascitis by clinical observation on the therapeutic effect test example below.
Embodiment 7
1, case selection
1.1 diagnostic criterias:
Adopt " myofascitis diagnostic criteria " in " new Chinese medicine guideline of clinical investigations ".(1) be apt to occur in neck, shoulder, waist, back, onset emergency differs.(2) clinical manifestation local pain, muscle spasm and the dyskinesia.(3) health check-up can find that affected part has local tenderness, and atrophy that muscle is slight can be laid one's hand on and " fiber inflammatory " tuberosity sometimes, and weight has the sense of aching.Common tenderness position is by trapezius muscle, supraspinatus, infraspinatus, posterior superior iliac spine and musculus sacrospinalis.4. auxiliary examination: x-ray check without abnormal, anti-" O ", erythrocyte sedimentation rate (ESR) are normal or higher, other index is many within normal range.
1.2 inclusive criterias:
(1) meet above-mentioned myofascitis diagnostic criteria; (2) 20～60 years old age, male or female; (3) 3 points≤lumbago VAS≤8 points (0～10 point of the score value scope) of marking; 4. this test of voluntary participation, and signature " Informed Consent Form ".
1.3 exclusion standards:
(1) there is spinal surgery history person; (2) there is serious spinal trauma history person; (3) iconography finding has the disorders such as spinal column sclerotin tumor, tuberculosis, osteoporosis; 4. merge serious disease or the insanes such as cardiovascular, cerebrovascular, hemopoietic, digestive system; 5. trimester of pregnancy and women breast-feeding their children; 6. the abnormal person of hepatic and renal function; 7. there are other autoimmune diseasees, allergic disease and acute and chronic infection person; 8. in nearly 1 month, accepted to treat Chinese and western drugs or other naturopathy measure person of primary disease; 9. researcher is thought and is not suitable for participating in this clinical trial person because of other reasons.
1.4 termination criteria:
(1) if patient's pain after treatment in 2 weeks by a definite date even adds severe one without obvious alleviation; (2) in therapeutic process, patient occurs that local skin is uncomfortable and waits the person that is not suitable for continuing external curing.
2, EXPERIMENTAL DESIGN
Test case is that qualified myofascitis patient is recruited in Shuguang Hospital's orthopedics department outpatient service, and case acquisition time is year February in November, 2011 to 2014.By 110 random digits of SAS (v9.2) Software Create, each random digit is stored in a lighttight seal envelopes, and preserved by a nurse who does not participate in research, confirming that patient meets into set condition and signs informed consent postscript and open envelope to confirm patient's grouping.Patient is randomized to either treatment group and matched group according to 1:1 ratio.
3, Therapeutic Method
Treatment group is accepted the hot-wet compress of 4 weeks external medicine compositions of the present invention by a definite date; Matched group is accepted 4 weeks by a definite date common hot-wet compresss.If patient's pain after treatment in 2 weeks by a definite date even increases the weight of without obvious alleviation, this patient will be terminated and test and proceed to Pain Management and receive treatment.
3.1 treatment groups:
Get the of the present invention damp and hot application that embodiment 1 prepares, 5～6 layers of gauze are immersed in medicine juice, in the time that temperature is down to 40 DEG C of left and right, gauze is taken out from medicine juice, extrude excessive moisture and spread on fast the most obvious position of pain, within every 30 minutes, change once, each treatment 1 hour, treats 1 every day, treats continuously after 5 days and has a rest and within 2 days, carry out successive treatment again.
3.2 matched groups:
5～6 layers of gauze are immersed in boiled water, in the time that temperature is down to 40 DEG C of left and right, gauze is taken out from water, extrude excessive moisture and spread on fast the most obvious position of pain, within every 30 minutes, change once, each treatment 1 hour, treats 1 every day, treats continuously after 5 days and has a rest and within 2 days, carry out successive treatment again.
4, observation item and method
This research adopts the evaluation of clinical curative effect index of pain visual imitation assessment method (visual analogue scale, VAS) as myofascitis.Respectively before treatment, treatment after, by 2 do not participate in treatment research worker carry out independently evaluation of clinical curative effect.VAS scoring is international pain measurement instrument, and it has good reliability and validity to pain measurement.Score value scope is 0～10 point, and the higher expression pain of mark is more serious, and 0 point indicates without pain, and 10 points of expressions have an intense pain and are impatient at.Observe and record the various untoward reaction that two groups of patients occur.
5, statistical method
Observed data adopts SPSS17.0 software to carry out statistical analysis.Measurement data with
represent, adopt t inspection; Enumeration data x
2inspection., there is statistical significance inspection level α=0.05 taking P<0.05 as difference.Curative effect evaluation adopts Intentionality treatment to analyze (intention-to-treat analysis, ITT), if patient does not have completed treatment to exit or be lost to follow-up, exit or last result data lost to follow-up is carried down (carry-forward) to supplement missing data with patient.
6, result
6.1 physical data:
Recruit to 151 routine myofascitis patients altogether, wherein 41 routine patients meet exclusion condition and are excluded, and have 110 routine cases and enter random packet, each 55 examples for the treatment of group and matched group.In therapeutic process, treatment group has 2 examples, matched group have 4 routine patients to be reluctant to continue to participate in test and exit.Following up a case by regular visits in process of latter 1 month for the treatment of, treatment group has 1 example because not participating in and follow up a case by regular visits in other places, and treatment group has that 50 cases are actual completes whole research; Matched group has 2 examples lost to follow-up, actually completes whole researcher 49 examples.
110 routine cases are Shuguang Hospital's orthopedics department in year April in January, 2011 to 2013, the outpatient service of massage section is recruited qualified myofascitis patient, wherein male's 45 examples, women's 65 examples; 28～60 years old age, average 45.41 years old; The course of disease 3～18 months, average 6.9 months.Two groups of Baseline Data difference not statistically significants (P>0.05), have comparability, in table 1.
Table 1 liang group physical data comparison
The 6.2VAS situation of change of marking:
After treatment in 4 weeks finishes, with two groups treat separately front comparison, VAS scoring after two groups of treatments all significantly reduces (P < 0.001), but the VAS for the treatment of group scoring fall is significantly greater than matched group (P < 0.001), in table 2.
Table 2 liang group VAS scoring situation of change comparison
Note: with this group before treatment, * P < 0.001; With the matched group comparison same period,
#p < 0.001; With the comparison of matched group difference, △ P < 0.001
6.3 untoward reaction:
There is local skin allergy in the routine patient for the treatment of group 1, stops treating local symptom after 1 day and disappear and completed follow-up test, and two groups have no other untoward reaction.
Persons of ordinary skill in the art may appreciate that the respective embodiments described above are to realize specific embodiments of the invention, and in actual applications, can do various changes to it in the form and details, and without departing from the spirit and scope of the present invention.
Claims (5)
1. treat the external medicine composition of myofascitis for one kind, it is characterized in that, made by the raw material of Chinese medicine of following weight portion: 10～30 parts of Radix Clematidis, 5～15 parts of Herba Lycopodiis, 5～15 parts of Cortex cercis chinensiss, 5～15 parts of Cortex erythrinaes, 5～15 parts of Rhizoma Chuanxiongs, 3～10 parts of Radix Notoginseng, 3～10 parts of Cortex Dictamni, 3～10 parts of Rhizoma Kaempferiae, 2～5 parts of Oleum Terebinthinaes.
2. the external medicine composition for the treatment of myofascitis according to claim 1, it is characterized in that, made by the raw material of Chinese medicine of following weight portion: 20 parts of Radix Clematidis, 10 parts of Herba Lycopodiis, 10 parts of Cortex cercis chinensiss, 10 parts of Cortex erythrinaes, 10 parts of Rhizoma Chuanxiongs, 5 parts of Radix Notoginseng, 6 parts of Cortex Dictamni, 6 parts of Rhizoma Kaempferiae, 3 parts of Oleum Terebinthinaes.
3. the preparation method of the external medicine composition for the treatment of myofascitis claimed in claim 1, is characterized in that, comprises following steps:
(1) take raw material of Chinese medicine Radix Clematidis, Herba Lycopodii, Cortex cercis chinensis, Cortex erythrinae, Rhizoma Chuanxiong, Radix Notoginseng, Cortex Dictamni and Rhizoma Kaempferiae according to weight portion proportioning claimed in claim 1, carry out water boiling and extraction;
(2) in the extracting solution obtaining in above-mentioned water boiling and extraction, add the Oleum Terebinthinae of weight portion described in claim 1, mix homogeneously, obtains the active component of external medicine composition of the present invention.
4. the preparation method of the external medicine composition for the treatment of myofascitis according to claim 3, it is characterized in that, further comprising the steps of: on the basis of described active component, further add pharmaceutically acceptable adjuvant, with conventional method of Chinese medicinal, be prepared into the regular dosage form of external medicine composition of the present invention.
5. according to the preparation method of the external medicine composition of the treatment myofascitis described in claim 3 or 4, it is characterized in that, described water boiling and extraction step is: each raw material of Chinese medicine is put into decocting medicine pot, and 3～7 times of volumes that add water, intense fire boils 15～25 minutes.
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| CN109432185A (en) * | 2018-12-14 | 2019-03-08 | 上海中医药大学附属曙光医院 | A kind of external medicine composition and its preparation method and application for treating myofascitis |
| CN115737730A (en) * | 2022-11-17 | 2023-03-07 | 南京中医药大学 | Traditional Chinese medicine composition for treating plantar fasciitis and preparation method thereof |
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| CN102526308A (en) * | 2011-12-27 | 2012-07-04 | 李承平 | Chinese medicinal formulation for external treatment by hot compression, fumigation and medicated bath |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109432185A (en) * | 2018-12-14 | 2019-03-08 | 上海中医药大学附属曙光医院 | A kind of external medicine composition and its preparation method and application for treating myofascitis |
| CN109432185B (en) * | 2018-12-14 | 2021-05-18 | 上海中医药大学附属曙光医院 | External traditional Chinese medicine composition for treating myofascitis and preparation method and application thereof |
| CN115737730A (en) * | 2022-11-17 | 2023-03-07 | 南京中医药大学 | Traditional Chinese medicine composition for treating plantar fasciitis and preparation method thereof |
| CN115737730B (en) * | 2022-11-17 | 2023-08-22 | 南京中医药大学 | Traditional Chinese medicine composition for treating plantar fasciitis and preparation method thereof |
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Application publication date: 20140917 |